JPS60168352A - Spreader of feed for fish farming - Google Patents

Abstract

PURPOSE:The titled spreader, consisting of sodium alginate, sodium polyacrylate and beer yeast, and having improved spreading property on cut feed or round bar food. CONSTITUTION:A spreader of feed for fish farming obtained by incorporating (a) a mixture of sodium alginate with sodium polyacrylate at 1:1-7 weight ratio with (b) beer yeast at 1:0.3-3 weight ratio between (a) and (b). A nutritious agent, feedin promoter, mineral , dyestuff, antioxidant, antimicrobial agent, etc. are mixed if necessary with the spreader, and 0.2-1% resultant mixture is added to a feed, e.g. a cut feed or round bar food. Thus, active constituents in drugs can be spread over the surface of the feed with a small amount of the spreader, and the feed can be taken in by cultured fish surely without outflow nor loss after feeding.

Description

[Detailed description of the invention] The present invention relates to a spreading agent for fish feed.

Currently, marine fish such as bush, sea bream, horse mackerel, blowfish, flounder, and coho salmon are farmed using Japanese sardines and hard sardines.

Highly caught fish such as mackerel, saury, locust, hake, and onion are minced according to the growth stage of the farmed fish.
This is done by cutting them (Kirimochi) or feeding them whole (Marutobyo). In other words, it is difficult for small fish to feed in Kirimochi and Marutai due to their small mouths, so they are usually minced and administered to large fish.On the other hand, when administered to large fish in minced form, the Not only does a strong water current scatter the mince finely, making the water cloudy and difficult to catch, but even if the cod is caught, it evaporates from between the cod along with the breathing water and hardly ever enters the esophagus, causing cut mochi and log disease. It is common to give. In some cases, these feeds (live baits) are fed as fresh fish without being frozen or preserved after being caught, but the timing of fishing, amount of fishing, area of fishing, etc. do not match the demands of the aquaculture industry. Because of this, they are often kept frozen until they are fed. Therefore, when feeding, frozen live food is thawed in the air or in water, but the disadvantages of thawing frozen fish are the loss of nutrients and environmental pollution due to the leaching of meat juices during thawing, as well as the risk of environmental pollution. There are problems with deterioration of freshness such as oxidation deterioration of fats and oils, deterioration of proteins and amino acids, decomposition of vitamins, and bacterial growth. There are also increasing methods of feeding fish directly.

On the other hand, as aquaculture and fisheries become more popular, fish diseases are becoming more common year by year, and as a countermeasure, there are increasing opportunities to supplement feed with nutrients or to mix antibacterial agents into feed and administer them orally. When adding nutrients or antibacterial agents to the above-mentioned feed format and feeding them to fish, simply adding and mixing them will cause the additives to dissolve into the water and dissipate, reducing the amount ingested by the fish. Generally, substances with adhesive or spreading properties (hereinafter sometimes referred to as glues) are used.
Efforts have been made to reduce elution and dissipation into the water by adding it to live bait along with nutrients and antibacterial agents, but most of these solutions involve adding a glue to the minced meat to prevent the bait itself from dissipating. This is intended to prevent the chemicals from escaping. Examples of thickening agents include guar gum and xanthan gum.

Locust bean gum, sodium alginate.

In addition to natural thickeners such as carrageenan, wheat gluten, and alpha synthetic fiber powder, sodium polyacrylate/1/acid and sodium carboxymethyl cellulose are used.

However, in the case of Kirimochi and log disease, the paste is not mixed with the bait like minced food, but is simply attached to the surface of the bait, so even if the paste gives good results with minced meat, it cannot be used as a drug. It is not possible to prevent the dissipation of additives such as
I can't say that there is still a glue that satisfies me. Particularly in the case of frozen feed for cut mochi and log disease, even if the glue is added to the feed as a powder, it will slide off the surface of the feed, so add water to the glue to make a paste-like liquid before adding it to the feed. Although there are methods such as pouring water on the surface of the frozen feed to thaw it a little and then sprinkling glue on it, most of the nutrients and drugs added by any of these methods are lost to the feed in water. The disadvantage that it is not ingested by fish because it separates from the water and dissipates is enormous.

The inventors of the present invention have made extensive studies to solve these drawbacks, and have found that by combining a specific type of paste in a specific ratio, and further mixing a specific ratio of B/l/drinking mash. We have completed the present invention by discovering that it has extremely excellent spreading properties on cut mochi and log disease containing frozen feed.

=3- That is, the present invention contains sodium alginate, sodium polyacrylate, and brewer's yeast, and the weight ratio of sodium alginate and sodium polyacrylate/1/acid is 1:1 to 7, and the total amount thereof and beer yeast in a weight ratio of 1:0.3 to 3.

As the sodium alginate, sodium polyacrylate, and brewer's yeast that constitute the spreading agent of the present invention, commercially available products can be used as appropriate. When mixing these three components, the order of mixing is not particularly limited, and examples include a method of mixing the three components at the same time, a method of mixing two components, and then adding the remaining component and mixing again. This can be carried out using a mixing method and apparatus known per se. Also,
At the time of mixing, water or other solvent may be added and mixed/stirred.
/For yeast, its dry weight is 0.0% relative to the total amount of sodium alginate and sodium polyacrylate.
As long as the ratio is between 3 and 3, 4- itself may be used in a moist state.

Among the above ratios, it is more preferable that the weight ratio of sodium alginate to sodium polyacrylate is 1:5 to 6, and that the weight ratio of their total amount to brewer's yeast is 1:1 to 2. More preferred.

Examples of the form of the spreading agent of the present invention include powder and pasty liquid, and the powder can also be used as pasty liquid by adding water or other solvents at the time of use. Also, as appropriate,
Excipients such as flour and rice bran may also be added.

The spreading agent of the present invention can be used, for example, by mixing a drug to be spread and adding it to cut mochi or log disease, or as a feed with an extremely low drug elution rate for cultivating various saltwater fish. be able to.

Examples of drugs that are likely to spread include nutritional supplements such as vitamins, chlorella, and garlic (4If).
enhancer, calcium, phosphorus, cobalt, magnesium,
These include mineflus such as zinc, pigments such as carotene, antioxidants to prevent rancidity of fats and oils in feed, and antibacterial agents such as cephalosporins, penicillin threads, tetracyclines, macrolides, sulfa drugs, and chloramphenicol. It will be done.

When mixing the spreading agent and the agent to be spread, for example, add sodium alginate, sodium polyacrylate, and brewer's yeast to a premixed and stirred mixture.
Alternatively, the preparation to be spread can be added to the mixture and stirred before mixing and stirring. The agent to be spread may be one type, or two or more types may be used as necessary. Further, depending on the drug to be spread, water (using one solvent, for example, as a solution, suspension, or emulsion) may be used for mixing with a spreading agent. Among the above-mentioned drugs, antibacterial agents are preferably mixed with the spreading agent of the present invention at the time of use.

Examples of the form of the mixture of the spreading agent of the present invention and the agent to be spread include powders and pasty liquids, and the composition is used as aquaculture feed for various freshwater fish by adding it to cut mochi and log disease. can do. When cut mochi or log rot is frozen, it is preferable to add a paste-like liquid or a paste-like liquid by adding water to the powder.

The spreading agent of the present invention may be added in an amount of 0.2 to 1% based on the feed, but the amount added should not be less than one-fifth of the amount of the drug to be spread. is preferred.

When used as a paste-like liquid, the appropriate amount of water to be added is 5 to 10 times the amount of the spreading agent of the present invention, but it may be adjusted as appropriate depending on the type of drug to be spread and the excipient. Needless to say, it is good.

The spreading agent of the present invention spreads the active ingredient of the drug on the surface of cut rice cakes and raw fish with log disease in a small amount, prevents it from being washed away or dissipated during feeding, and ensures that it is ingested by farmed fish, thereby increasing the effectiveness of the drug. Extremely accurate and high.

Sodium polyacrylate constituting the spreading agent of the present invention,
Sodium alginate is well known as a glue for mixed feed and raw minced feed, and is an easily available and highly safe substance. Brewer's yeast is also beneficial to fish, as it is often used as an auxiliary ingredient in feed as a source of trace nutrients such as vitamins and minerals.

EXAMPLES Experimental examples and examples will be shown below to specifically explain the present invention, but the present invention should not be limited to these.

Experimental Example 1 - Approximately 10 pieces of sardines (50g in weight) frozen in
111111 cut into lengths (frozen cut bait), cut and thawed by leaving at room temperature (24"C) for 60 minutes (thawed cut mochi), and thawed and minced (minced bait) are prepared. On the other hand, 8 g of water was added to a mixture of glue 19 and a preparation tg (LOOIP titer) in which the antibiotic ampicillin was triturated with lactose, mixed well, and 3 g of the mixture was added to the above raw bait 100 min. After the addition, the mixture was well stirred and placed in a container containing 300 s/liter of seawater (inner diameter 13.0 liters), which had been shaken in advance with a horizontal shaker (120 times per minute).
8 cm) and shaken for 5 seconds. After shaking 1
Sieve the entire amount through a 0-mesh sieve, put only the sieved portion into a stoppered Erlenmeyer flask, and shake for 5 minutes with a vertical shaker (300 mouths shaking per minute) to make a homogeneous liquid. The amount of ampicillin contained therein was quantified using a bioassay method, the total amount eluted into seawater was calculated, and the elution rate (%) relative to the amount added to the bait was calculated.

As shown in Table 1, the dissolution rate was generally lower for minced meat than for cut rice cakes. Among the starch ingredients, sodium alginate and sodium polyacrylate had a low elution rate in minced meat alone, and a mixture of them had a low elution rate in cut mochi, but by combining brewer's yeast, the elution rate was further reduced in cut mochi. The effect of the present invention as a spreading agent was the most excellent.

Table 1 Locust Bean Gum 16.4 Omi 46 lll 5
44 Gum Arabic 240 1 41.3' -**
Pectin 241; 68.8' -**Sodium alginate 8.21 18.6 21.9 Carrageenan 14.0 47.9 5λ2 Farcelan 14.0
50.1 5a3 xanthus gum 11.6 ' 3
5.5 57.5 Polyacryno W Sodium 7.6
, 17.2 31.5 Argiogadolium 1 part
゛1 part of polyacrynoitorium, 7.3' 4.1
471 (This invention) □ Ne Ampicillin was added and mixed into the feed** Experimental example 2 not measured The elution rate of ampicillin in frozen bait was determined in the same manner as in Experimental Example 1 using yeast other than Bee μ yeast and yeast extract, as well as a paste containing extracts rich in protein and minerals like Bee/14 mother. compared. As shown in Table 2, the results confirmed that the present invention was superior to any combination.

Table 2 Experimental Example 3 In order to examine the blending ratio of sodium alginate, sodium polyacrylate, and B/14 base of the present invention and their effectiveness as a spreading agent, various formulations were freeze-cut using the method shown in Experimental Example 1. The dissolution rate of ampicillin in the feed was measured.

The results are shown in Table 3.

Example 1 A mixture of 15% sodium alginate, 35% sodium polyacrylate, 50% brewer's yeast 0.4 kfl and a commercially available vitamin preparation with the composition shown in Table 4 0.6 klj
After mixing well, add water to make 4 to 9, stir well with a whistle to make a homogeneous liquid, add it to 200 g of frozen sardine slices, mix, and then feed this bait to a fish weighing 0.9 kg.
72.0 (By feeding 10 fish per day, twice a day, the growth slowdown and disease outbreak caused by continuous administration of sardines can be prevented. be able to.

Vitamin B+ 6 Q Inositol 3g Vitamin B
t 3g Vitamin A 500,000 units Vitamin B.2
g Vitamin D3 loMi vitamin K O, 29 Vitamin E 8 g Niche 4 role amide 5 g Vitamin C 15 g Panthio-calcium 10 9 Wheat flour Residue Acid 0.5 g Example 2 Sodium alginate 5%, Sodium polyacrylate 25% Mix well 0.8 kg of a mixture of 70% brewer's yeast and 2 kg of sulfisozole milk, a sulfa drug, and sprinkle it over 150 kg of thawed small mackerel log bait while stirring to prevent it from becoming lopsided as much as possible. It is given to each ton of farmed yellowtail that is infected with Nocardia disease. By continuing this daily dose for 7 to 10 days, effective treatment results for Nocardia disease can be obtained.

Example 3 A mixture with the composition shown in Tables 5 and 6 was prepared, 0.3 kg of the mixture was added with 1.5 kQ of water, stirred and mixed, and spread on 100 # of thawed cut saury bait for one day. Once, weight 0.
By feeding 41,500 7kQ farmed Ladda every day,
It makes up for the lack of vitamin B caused by feeding saury, prevents liver damage caused by fat peroxide, and allows red sea bream to grow in good health.

Table 5 Composition of the mixture Sodium alginate 8% Polyacrylic/I/storium acid 32% Vitamin mixture 9 5% Brewer's yeast 55% Dibenzoylthiamine 4.09 Biotin 4. Oq
Vitamin Bs 3.69 Choline chloride 10.09 Vitamin B @ 4.4g Inosito-1v2.9 Vitamin B
+94'! / Vitamin A 2 million units Nicotinamide 6.09 Vitamin D 3.4 million degree pantochi 4
Back cuckoo 4 times 10. Og Vitamin E 8. OIF folic acid 0.69 Flour residual vitamin C 15.0g

Claims (1)

[Claims] It contains sodium alginate, sodium polyacrylate, and brewer's yeast, the weight ratio of sodium alginate and sodium polyacrylate is 1:1 to 7, and the weight ratio of their total amount to brewer's yeast is 1:0.
3 or 3. A spreading agent for fish feed.