JPS6058924A - 従属栄養クロレラを有効成分とする血圧降下及び脳卒中予防剤 - Google Patents
従属栄養クロレラを有効成分とする血圧降下及び脳卒中予防剤Info
- Publication number
- JPS6058924A JPS6058924A JP58167375A JP16737583A JPS6058924A JP S6058924 A JPS6058924 A JP S6058924A JP 58167375 A JP58167375 A JP 58167375A JP 16737583 A JP16737583 A JP 16737583A JP S6058924 A JPS6058924 A JP S6058924A
- Authority
- JP
- Japan
- Prior art keywords
- chlorella
- strain
- cellulose
- hypotensor
- cgf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000195649 Chlorella <Chlorellales> Species 0.000 title abstract description 40
- 230000003449 preventive effect Effects 0.000 title abstract description 3
- 206010033799 Paralysis Diseases 0.000 title abstract 2
- 230000002490 cerebral effect Effects 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 210000002421 cell wall Anatomy 0.000 claims abstract description 7
- 239000004480 active ingredient Substances 0.000 claims abstract description 5
- 230000036772 blood pressure Effects 0.000 claims description 11
- 240000009108 Chlorella vulgaris Species 0.000 claims description 9
- 235000007089 Chlorella vulgaris Nutrition 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000009861 stroke prevention Effects 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 6
- 210000004027 cell Anatomy 0.000 abstract description 4
- 238000000926 separation method Methods 0.000 abstract description 4
- 230000002950 deficient Effects 0.000 abstract description 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 210000005056 cell body Anatomy 0.000 abstract 1
- 230000001066 destructive effect Effects 0.000 abstract 1
- 230000001079 digestive effect Effects 0.000 abstract 1
- 230000036543 hypotension Effects 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 238000000053 physical method Methods 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 description 10
- 241000700159 Rattus Species 0.000 description 9
- 238000002474 experimental method Methods 0.000 description 9
- 235000019621 digestibility Nutrition 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 235000005911 diet Nutrition 0.000 description 5
- 230000037213 diet Effects 0.000 description 5
- 230000004083 survival effect Effects 0.000 description 5
- 230000003276 anti-hypertensive effect Effects 0.000 description 4
- 206010020772 Hypertension Diseases 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 108090000284 Pepsin A Proteins 0.000 description 3
- 102000057297 Pepsin A Human genes 0.000 description 3
- 102000004142 Trypsin Human genes 0.000 description 3
- 108090000631 Trypsin Proteins 0.000 description 3
- 230000001651 autotrophic effect Effects 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 238000010253 intravenous injection Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229940111202 pepsin Drugs 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 239000012588 trypsin Substances 0.000 description 3
- 206010051290 Central nervous system lesion Diseases 0.000 description 2
- 235000019750 Crude protein Nutrition 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 108090000783 Renin Proteins 0.000 description 2
- 102100028255 Renin Human genes 0.000 description 2
- 230000004531 blood pressure lowering effect Effects 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 241000195628 Chlorophyta Species 0.000 description 1
- 235000019743 Choline chloride Nutrition 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229940030600 antihypertensive agent Drugs 0.000 description 1
- 239000002220 antihypertensive agent Substances 0.000 description 1
- 238000011888 autopsy Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229960003178 choline chloride Drugs 0.000 description 1
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 235000019814 powdered cellulose Nutrition 0.000 description 1
- 229920003124 powdered cellulose Polymers 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58167375A JPS6058924A (ja) | 1983-09-10 | 1983-09-10 | 従属栄養クロレラを有効成分とする血圧降下及び脳卒中予防剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58167375A JPS6058924A (ja) | 1983-09-10 | 1983-09-10 | 従属栄養クロレラを有効成分とする血圧降下及び脳卒中予防剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6058924A true JPS6058924A (ja) | 1985-04-05 |
| JPH0475206B2 JPH0475206B2 (de) | 1992-11-30 |
Family
ID=15848544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58167375A Granted JPS6058924A (ja) | 1983-09-10 | 1983-09-10 | 従属栄養クロレラを有効成分とする血圧降下及び脳卒中予防剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6058924A (de) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5538336A (en) * | 1978-09-12 | 1980-03-17 | Kurorera Kogyo Kk | Extraction of hypotensive substance |
| JPS55164629A (en) * | 1979-06-07 | 1980-12-22 | Kurorera Kogyo Kk | Extraction of arteriosclerosis-suppressing substance |
| JPS5829074A (ja) * | 1981-08-14 | 1983-02-21 | Toshiba Corp | 光学的文字読取装置 |
-
1983
- 1983-09-10 JP JP58167375A patent/JPS6058924A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5538336A (en) * | 1978-09-12 | 1980-03-17 | Kurorera Kogyo Kk | Extraction of hypotensive substance |
| JPS55164629A (en) * | 1979-06-07 | 1980-12-22 | Kurorera Kogyo Kk | Extraction of arteriosclerosis-suppressing substance |
| JPS5829074A (ja) * | 1981-08-14 | 1983-02-21 | Toshiba Corp | 光学的文字読取装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0475206B2 (de) | 1992-11-30 |
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