JPS61502817A - ゲル含有製剤学的調製物 - Google Patents

ゲル含有製剤学的調製物

Info

Publication number: JPS61502817A
Authority: JP; Japan
Prior art keywords: agent; active substance; pluronic; drug; prostaglandin
Prior art date: 1984-07-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP60503347A

Other languages

English (en)

Japanese (ja)

Inventor

ベター，ベルナルト

グローセ，エーフエリイン

ツインマーマン，イングフリート

タツク，ヨハネス‐ヴイルヘルム

Original Assignee

シエ−リング　アクチエンゲゼルシヤフト

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-27

Filing date

1985-07-18

Publication date

1986-12-04

1985-07-18 Application filed by シエ−リング　アクチエンゲゼルシヤフト filed Critical シエ−リング　アクチエンゲゼルシヤフト

1986-12-04 Publication of JPS61502817A publication Critical patent/JPS61502817A/ja

Status Pending legal-status Critical Current

Links

239000000825 pharmaceutical preparation Substances 0.000 title claims description 4
239000013543 active substance Substances 0.000 claims description 20
239000003795 chemical substances by application Substances 0.000 claims description 14
229920001992 poloxamer 407 Polymers 0.000 claims description 13
239000003814 drug Substances 0.000 claims description 12
239000002872 contrast media Substances 0.000 claims description 10
238000004519 manufacturing process Methods 0.000 claims description 10
229940079593 drug Drugs 0.000 claims description 9
229920001983 poloxamer Polymers 0.000 claims description 8
150000003180 prostaglandins Chemical class 0.000 claims description 5
239000003242 anti bacterial agent Substances 0.000 claims description 3
229940121375 antifungal agent Drugs 0.000 claims description 3
239000003429 antifungal agent Substances 0.000 claims description 3
238000002360 preparation method Methods 0.000 claims description 3
239000003270 steroid hormone Substances 0.000 claims description 3
239000000032 diagnostic agent Substances 0.000 claims 4
229940039227 diagnostic agent Drugs 0.000 claims 4
238000002405 diagnostic procedure Methods 0.000 claims 3
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 2
230000003115 biocidal effect Effects 0.000 claims 2
229940011871 estrogen Drugs 0.000 claims 2
239000000262 estrogen Substances 0.000 claims 2
229910052740 iodine Inorganic materials 0.000 claims 2
239000011630 iodine Substances 0.000 claims 2
229940127557 pharmaceutical product Drugs 0.000 claims 2
238000002604 ultrasonography Methods 0.000 claims 2
206010000234 Abortion spontaneous Diseases 0.000 claims 1
238000005520 cutting process Methods 0.000 claims 1
XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 claims 1
229960002986 dinoprostone Drugs 0.000 claims 1
239000012216 imaging agent Substances 0.000 claims 1
238000003384 imaging method Methods 0.000 claims 1
230000000977 initiatory effect Effects 0.000 claims 1
208000015994 miscarriage Diseases 0.000 claims 1
239000008177 pharmaceutical agent Substances 0.000 claims 1
XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 claims 1
150000003166 prostaglandin E2 derivatives Chemical class 0.000 claims 1
208000000995 spontaneous abortion Diseases 0.000 claims 1
238000009472 formulation Methods 0.000 description 16
239000000203 mixture Substances 0.000 description 16
239000000243 solution Substances 0.000 description 13
239000000499 gel Substances 0.000 description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
239000007864 aqueous solution Substances 0.000 description 3
230000001225 therapeutic effect Effects 0.000 description 3
RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 2
-1 Polyoxyethylene Polymers 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000036760 body temperature Effects 0.000 description 2
238000010586 diagram Methods 0.000 description 2
238000002347 injection Methods 0.000 description 2
239000007924 injection Substances 0.000 description 2
238000000034 method Methods 0.000 description 2
229940094443 oxytocics prostaglandins Drugs 0.000 description 2
241000512259 Ascophyllum nodosum Species 0.000 description 1
241000700198 Cavia Species 0.000 description 1
102000011782 Keratins Human genes 0.000 description 1
108010076876 Keratins Proteins 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 description 1
229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
208000036029 Uterine contractions during pregnancy Diseases 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
239000012670 alkaline solution Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
239000012752 auxiliary agent Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
229920001400 block copolymer Polymers 0.000 description 1
230000000903 blocking effect Effects 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
238000001816 cooling Methods 0.000 description 1
239000003599 detergent Substances 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
SDIXRDNYIMOKSG-UHFFFAOYSA-L disodium methyl arsenate Chemical compound [Na+].[Na+].C[As]([O-])([O-])=O SDIXRDNYIMOKSG-UHFFFAOYSA-L 0.000 description 1
239000013583 drug formulation Substances 0.000 description 1
239000002961 echo contrast media Substances 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
239000010931 gold Substances 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
239000012456 homogeneous solution Substances 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920001451 polypropylene glycol Polymers 0.000 description 1
239000011148 porous material Substances 0.000 description 1
230000000069 prophylactic effect Effects 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
239000007921 spray Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
229960003400 sulprostone Drugs 0.000 description 1
UQZVCDCIMBLVNR-TWYODKAFSA-N sulprostone Chemical compound O[C@@H]1CC(=O)[C@H](C\C=C/CCCC(=O)NS(=O)(=O)C)[C@H]1\C=C\[C@@H](O)COC1=CC=CC=C1 UQZVCDCIMBLVNR-TWYODKAFSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)

JP60503347A 1984-07-27 1985-07-18 ゲル含有製剤学的調製物 Pending JPS61502817A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19843428264 DE3428264A1 (de)	1984-07-27	1984-07-27	Gelhaltige pharmazeutische zubereitungen
DE3428264.5		1984-07-27

Publications (1)

Publication Number	Publication Date
JPS61502817A true JPS61502817A (ja)	1986-12-04

Family

ID=6242046

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP60503347A Pending JPS61502817A (ja)	1984-07-27	1985-07-18	ゲル含有製剤学的調製物

Country Status (8)

Country	Link
EP (1)	EP0227656A1 (da)
JP (1)	JPS61502817A (da)
AU (1)	AU4672385A (da)
DE (1)	DE3428264A1 (da)
DK (1)	DK111686A (da)
ES (1)	ES8705763A1 (da)
IL (1)	IL75921A0 (da)
WO (1)	WO1986000813A1 (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990012576A1 (fr) *	1989-04-25	1990-11-01	The Green Cross Corporation	Composition liquide de prostaglandine
JPH07309782A (ja) *	1994-01-24	1995-11-28	Takahiro Ogawa	造影剤

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0386960A3 (en) *	1989-03-07	1991-10-23	American Cyanamid Company	Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings
CA2040460C (en) *	1990-05-01	1997-06-10	Tacey X. Viegas	Drug delivery with thermoreversible gels
US5593683A (en) *	1990-05-01	1997-01-14	Mdv Technologies, Inc.	Method of making thermoreversible polyoxyalkylene gels
US5948387A (en) *	1990-06-01	1999-09-07	Imarx Pharmaceutical Corp.	Contrast media for ultrasonic imaging
WO1994028872A1 (en) *	1993-06-04	1994-12-22	Warner-Lambert Company	Non-alcoholic cold and sinus medication
US6669927B2 (en)	1998-11-12	2003-12-30	3M Innovative Properties Company	Dental compositions
US6312666B1 (en)	1998-11-12	2001-11-06	3M Innovative Properties Company	Methods of whitening teeth
US6312667B1 (en)	1998-11-12	2001-11-06	3M Innovative Properties Company	Methods of etching hard tissue in the oral environment
US6620405B2 (en) *	2001-11-01	2003-09-16	3M Innovative Properties Company	Delivery of hydrogel compositions as a fine mist
EP3790597A4 (en) *	2018-07-12	2022-03-09	Arshintseva, Elena Valentinovna	THERMAL PROCESS FOR THE STERILIZATION OF POLOXAMER WITH LIQUID PHARMACEUTICALS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3867521A (en) *	1970-08-26	1975-02-18	Scherer Corp R P	Method for absorption of drugs
US3852210A (en) *	1972-08-11	1974-12-03	Flow Pharma Inc	Stable liquid detergent concentrates containing active oxygen
CA1051776A (en) *	1974-08-09	1979-04-03	Murray W. Winicov	Poloxamer-iodine gel
US4100271A (en) *	1976-02-26	1978-07-11	Cooper Laboratories, Inc.	Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
CA1072413A (en) *	1976-07-13	1980-02-26	West Laboratories	Poloxamer gel systems with gelling temperatures higher than room temperature
US4365516A (en) *	1978-01-06	1982-12-28	Rockwell International Corporation	Ultrasonic couplant gel compositions and method for employing same
DE2966768D1 (en) *	1978-12-19	1984-04-12	Byk Gulden Lomberg Chem Fab	Solutions of x-ray contrast agents
SE431821B (sv) *	1979-01-29	1984-03-05	Perstorp Ab	Lagringsstabilt, prostaglandininnehallande medicinskt preparat

1984
- 1984-07-27 DE DE19843428264 patent/DE3428264A1/de not_active Withdrawn
1985
- 1985-07-18 JP JP60503347A patent/JPS61502817A/ja active Pending
- 1985-07-18 AU AU46723/85A patent/AU4672385A/en not_active Abandoned
- 1985-07-18 EP EP85903649A patent/EP0227656A1/de not_active Withdrawn
- 1985-07-18 WO PCT/DE1985/000237 patent/WO1986000813A1/de not_active Ceased
- 1985-07-26 ES ES545616A patent/ES8705763A1/es not_active Expired
- 1985-07-26 IL IL75921A patent/IL75921A0/xx unknown
1986
- 1986-03-11 DK DK111686A patent/DK111686A/da not_active Application Discontinuation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990012576A1 (fr) *	1989-04-25	1990-11-01	The Green Cross Corporation	Composition liquide de prostaglandine
JPH07309782A (ja) *	1994-01-24	1995-11-28	Takahiro Ogawa	造影剤

Also Published As

Publication number	Publication date
IL75921A0 (en)	1985-12-31
DK111686D0 (da)	1986-03-11
ES545616A0 (es)	1987-06-01
AU4672385A (en)	1986-02-25
DK111686A (da)	1986-03-11
WO1986000813A1 (fr)	1986-02-13
DE3428264A1 (de)	1986-03-06
EP0227656A1 (de)	1987-07-08
ES8705763A1 (es)	1987-06-01

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EP0946143B1 (en)	2006-04-19	A nitroimidazole gel composition
EP0662320B1 (en)	2001-05-30	Dry gel composition
FI103714B (fi)	1999-08-31	Geeliä muodostava nesteväliainekoostumus
US3711602A (en)	1973-01-16	Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso
JP4555402B2 (ja)	2010-09-29	痔核用組成物および使用方法
US5847023A (en)	1998-12-08	Thermal irreversible gel corneal contact lens formed in situ
US5071644A (en)	1991-12-10	Topical drug delivery with thermo-irreversible gels
JPS62190119A (ja)	1987-08-20	高粘度ヒドロゲル又は懸濁液を得るための製剤
JPS61502817A (ja)	1986-12-04	ゲル含有製剤学的調製物
US5376693A (en)	1994-12-27	Thermo-irreversible gel corneal contact lens formed in situ
JPH02300114A (ja)	1990-12-12	薬物送達組成物と外傷包帯組成物
EA015356B1 (ru)	2011-06-30	Способы лечения эндометриоза
JPS63253023A (ja)	1988-10-20	アセトアゾラミドを含有する安定な眼科用製剤
JP4449213B2 (ja)	2010-04-14	坐剤用組成物
JPH08253412A (ja)	1996-10-01	ポリエチレングリコールのためのゲル化剤
SE431821B (sv)	1984-03-05	Lagringsstabilt, prostaglandininnehallande medicinskt preparat
KR20210099553A (ko)	2021-08-12	주사 가능한 서방형 항생 제제
JPS5931714A (ja)	1984-02-20	避妊組成物
JP2023547578A (ja)	2023-11-13	新規な獣用子宮注入剤、その調製方法及び使用
KR102089117B1 (ko)	2020-04-16	올리고머 락트산을 포함하는 약제학적 조성물
JPS63166832A (ja)	1988-07-11	鼻用溶液
JPH04502004A (ja)	1992-04-09	オキシプリノールおよび／またはそのアルカリおよびアルカリ土類塩の調合物
JPH0364483B2 (da)	1991-10-07
JP2018535253A (ja)	2018-11-29	女性対象における不妊症の治療ための組成物
WO2024194781A1 (en)	2024-09-26	Improved compositions

JPS61502817A - ゲル含有製剤学的調製物 - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (2)

Publications (1)

Family

ID=6242046

Family Applications (1)

Country Status (8)

Cited By (2)

Families Citing this family (10)

Family Cites Families (8)

Cited By (2)

Also Published As

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