JPS6176406A - Drugs in plastic containers - Google Patents

Abstract

PURPOSE:The titled drug prevented from deformation of a container by substituting the air in the space thereof with nitrogen gas when enclosing an emusifiable concentrate containing O-secondary-butylphenyl N-methyl-carbamate and a specific surfactant in a plastic container. CONSTITUTION:A drug in a plastic container capable of improving a commodity value by preventing a change of external appearance with the passage of time by protecting a container from deformation occurring during preservation of products by substituting the air in an upper space of the container made after charging a specific amount of the drug therein with nitrogen gas when producing the above-mentioned contained drug useful to control agriculturally, disin fectionally and industrially harmful microorganisms, insects and weeds by enclos ing an emulsifiable concentrate containing O-secondary-butylphenyl N-methyl carbamate and 1 or more of surfactants selected from polyoxyalkylene alkylaryl ether and alkylarylsulfonate in the plastic container.

Description

Detailed Description of the Invention (Field of Industrial Application) The present invention provides a chemical agent packed in a plastic container useful for controlling microorganisms, insects, weeds, etc. that are harmful in agriculture, epidemic prevention, and industry. This is what we provide. The purpose of this is to prevent deformation of the container that occurs during storage of a product, prevent changes in appearance that occur regularly, and improve the commercial value of the product.

(Prior art) Plastic containers have been used as supplies in various fields in place of glass bottles because of their resistance to breakage, ease of cleanup after use, and the ability to be incinerated. Widely used for packaging.

(The point to be solved by the invention) Plastic containers that have many advantages as described above are also 1.
Disadvantages include changes in the contents, slight permeability to gases and liquid vapors, and corrosion of the container by special solvents, 1 which leads to deformation of the container.

In order to prevent this, we have conventionally investigated container materials and solvents, and increased the area weight, but these methods have been expensive in terms of cost.For example, in the case of pesticides, when spraying them on plants, There are only a few cases in which it has been sufficiently successful in causing drug damage. Of course, not all drugs deform plastic containers (types of drugs, solvent 1 surfactant 1)
In some cases, deformation is prevented by selecting auxiliary agents.

(Means for solving the intercondylar point)
- Keimi 1 made of plastic, which was made by intensive research on the deformation of the container for drugs containing an emulsion containing secondary butylphenyl N-methyl carbamate (hereinafter referred to as BPMO) and polyoxyalkylene alkylaryl ether or alkylaryl sulfonate. After putting a certain amount of drug into the container, we replace the air in a part of the space with nitrogen gas.
I was able to prevent the dent and found my heart. In terms of packaging technology, filling a container with nitrogen gas is used to prevent deterioration of the contents due to oxidation in food products, etc.
There are no examples of nitrogen gas being filled in to prevent deformation of containers made of plastic.

The general formula of the polyoxyalkylene alkylaryl ether used in the present invention is as follows.

RAr O(-(OHm), o-3-nH (S in the formula
R is an alkyl group, Ar is a phenyl group, and N is a naphthyl group.
m % n represents an integer. ) Specific examples include polyoxyethylene octylphenyl ether, polyoxyethylene isooctyl phenyl ether, polyoxyethylene nonylphenyl ether, and the like.

Further, 1-alkylaryl sulfonate is exemplified by the general formula %. However, in the formula, R' represents an alkyl group, Ar represents a phenyl group or naphthyl group, and M represents a salt-forming group. n indicates an integer.

Specifically, sodium salts such as dodecylbenzenesulfonic acid, dipropylnaphthalenesulfonic acid, dibutylnaphthalenesulfonic acid, dioctylnaphthalenesulfonic acid, etc.
Potassium salts 1 Calcium salts and amine salts are listed.

In addition to the above-mentioned surfactants, the drug of the present invention includes mono-anionic surfactants such as sodium lauryl sulfate, sodium oleyl sulfate, sodium oleate sulfate, and sodium isethionate sulfate. Nonionic surfactants. Polyoxyethylene fatty acid ester, polyoxyethylene sorbitan monolaurate 1 as agent
Examples include polyoxyethylene sorbitol laure-1, polyoxyethylene sorbitol oleate, and polyoxyethylene derivatives of tall oil fatty acid lubitol ester. These surfactants can also be used in combination.As organic solvents, benzene, xylene, aromatic hydrocarbon/ketone solvents such as toluene, alcoholic solvents,
An aliphatic hydrocarbon solvent is used.

Next, the plastic container used in the present invention is usually
Containers are manufactured industrially by blow molding, and are made of materials such as polypropylene, low density polyethylene, high density polyethylene 1 polyester, vinyl chloride, polyvinylidene chloride, and nylon.

The capacity of plastic containers is 1.For example, those commonly used for agricultural chemicals are 100CC, 300CG, and 500CC.

i e3.5-el and 18.13, etc., but the volume and size of the drug according to the present invention are not particularly important.

Next, in the method for producing a drug packaged in a plastic container of the present invention, a BPMo solvent, a surfactant, etc. are added to a plastic container, and after dissolving, the emulsion is uniformly mixed and the resulting emulsion is poured into a plastic container at a constant rate using a filling machine. After filling the container, a simple method of filling the upper space with nitrogen gas directly through a nozzle may be sufficient.

The drug of the present invention can also contain active ingredients other than BPMO. It would be perfect if nitrogen gas was sealed in after the air in the space was absorbed and removed, but if more than about the space in the upper layer is replaced with nitrogen, the deformation of the container, which is the purpose of the present invention, can be prevented. .

(Example) Next, the present invention will be specifically explained with reference to Examples.

(Example 1) Salicion 27 in a 500CC plastic container
Parts by weight - xylene 63 parts by weight \ polyoxyethylene nonylphenyl ether 3 parts by weight - totisylbenzenesulfonic acid calcium salt 5 ff1ii.

An emulsion in which 2 parts by weight of polyoxyethylene fatty acid ester was uniformly dissolved was added, and nitrogen gas was then introduced to replace the air remaining in the container.

(Example 2) 20 parts by weight of BPMO S in a 500-piece plastic container
0.0-dimethyl-〇-(3-methyl-4-nitrophenyl)naophosphate 3011i parts, xylene 4
Example 1 Example 1 Do the same as.

(Function) Although the mechanism of preventing deformation of plastic containers by nitrogen gas filling according to the present invention is not fully elucidated,
As follows (estimated)

(1) Difference in reactivity of air and nitrogen to drugs.

Among the active ingredients of the drug, 1 superactive agent, 1 surfactant, and 1 other ingredients, there are some that undergo oxidative decomposition little by little. As the oxygen in the air is digested by the decomposition reaction, the pressure inside the container progresses and the container becomes ``dented.'' However, by replacing it with nitrogen, oxidative decomposition and depressurization can be prevented and the deformation of 1 volume can be prevented. It can be prevented.

(2) Differences in the reactivity of air and nitrogen to plastic containers.

Nitrogen has less influence on the container itself than air, such as oxidation and corrosion, so deformation of the container can be prevented.

(Effects of the Invention) In the nitrogen gas-filled drug of the present invention, the plastic container used as the packaging container thereof does not deform over a long period of time. Next, the effect will be explained using test examples.

(Test example) (11 Test container 500 CG capacity plastic container used for agricultural chemicals 1 Material: Carb) Nylon double layer
56 ± 12 (2) Nitrogen gas filling procedure After filling each drug into a SOCC plastic container (5 bottles per drug) (a) Nitrogen gas filled product: Inject gas from the container mouth for 20 seconds (b) Products filled with nitrogen gas: % of the space volume was replanted with soybean using a vacuum trap, and both were sealed with caps after filling.

(31 Storage conditions: left at room temperature for 30 days and 60 days (March to April)
(4) Deformation rate: The outer diameter of the center of the body of the container was measured, and the deformation rate was calculated using the following formula.

Note that if the deformation rate is less than 74, the deformation will not be visible to the naked eye. do not feel.

(5) Results: Shown in Table 1.

Table 1

Claims (1)

[Claims] placing an emulsion containing o-secondary butylphenyl N-methyl carbamate and one or more surfactants selected from polyoxyalkylene alkylaryl ether and alkylaryl sulfonate in a plastic container;
A drug packaged in a plastic container that replaces the air in the space with nitrogen gas.