JPS6416708A - Composition for extracting sphingolipid and method for extraction thereof - Google Patents

Composition for extracting sphingolipid and method for extraction thereof

Info

Publication number
JPS6416708A
JPS6416708A JP62170752A JP17075287A JPS6416708A JP S6416708 A JPS6416708 A JP S6416708A JP 62170752 A JP62170752 A JP 62170752A JP 17075287 A JP17075287 A JP 17075287A JP S6416708 A JPS6416708 A JP S6416708A
Authority
JP
Japan
Prior art keywords
sphingolipid
composition
agent
sulfatide
sphingomyelin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62170752A
Other languages
Japanese (ja)
Inventor
Kenji Matsui
Yutaka Ando
Kyoko Hitomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ichimaru Pharcos Co Ltd
Original Assignee
Ichimaru Pharcos Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ichimaru Pharcos Co Ltd filed Critical Ichimaru Pharcos Co Ltd
Priority to JP62170752A priority Critical patent/JPS6416708A/en
Publication of JPS6416708A publication Critical patent/JPS6416708A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PURPOSE:To obtain the titled composition, containing cerebroside, sulfatide and sphingomyelin in specific amounts or more as main constituent substances and useful as an emulsion stabilizer for cosmetics or medicines, liposome forming agent, etc. CONSTITUTION:A sphingolipid contained in a visceral tissue, such as bovine brain, is extracted. In the process, a mixed solvent containing hexane and isopropanol at 9:5 ratio of the former to the latter is used a solvent in crude extraction thereof to efficiently afford the aimed sphingolipid extract composition, containing cerebroside, sulfatide and sphingomyelin as main constituent substances in a high purity of >=30.0% when determined as sphingosine and useful as the above-mentioned stabilizer, agent and a protecting agent for the skin or hair, remedy for xeroderma accompanied by pruritis, etc., on an industrial production scale by simple operation. Furthermore, phospholipid can also be extracted in high purity without waste.
JP62170752A 1987-07-08 1987-07-08 Composition for extracting sphingolipid and method for extraction thereof Pending JPS6416708A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62170752A JPS6416708A (en) 1987-07-08 1987-07-08 Composition for extracting sphingolipid and method for extraction thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62170752A JPS6416708A (en) 1987-07-08 1987-07-08 Composition for extracting sphingolipid and method for extraction thereof

Publications (1)

Publication Number Publication Date
JPS6416708A true JPS6416708A (en) 1989-01-20

Family

ID=15910732

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62170752A Pending JPS6416708A (en) 1987-07-08 1987-07-08 Composition for extracting sphingolipid and method for extraction thereof

Country Status (1)

Country Link
JP (1) JPS6416708A (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2692781A1 (en) * 1992-06-24 1993-12-31 Sederma Sa Cosmetic compsn., for improving skin - contains sphingomyelin(s) of milk or fish as natural precursor ceramide(s), avoiding use of sphingo:lipid(s) from mammals, esp. cattle
JPH06179613A (en) * 1992-12-12 1994-06-28 Taiyo Kagaku Co Ltd Cosmetics
JPH06199627A (en) * 1992-12-26 1994-07-19 Taiyo Kagaku Co Ltd Cosmetics
JPH08506811A (en) * 1993-02-11 1996-07-23 スベンスカ、メジェリールナス、リクスフェレニング、エコノミー、アクチェボラーグ Sphingomyelin extraction method
JPH08217666A (en) * 1995-02-10 1996-08-27 Mikimoto Pharmaceut Co Ltd Oil-in-water type cream base
FR2752526A1 (en) * 1996-08-26 1998-02-27 Dong Kook Pharm Co Ltd ANTIHEMOLYTIC LIPOSOMAL PREPARATION
US5912152A (en) * 1995-02-28 1999-06-15 Yakurigaku Chuo Kenkyusho Process for preparing sphingomyelin and ceramide from erythrocyte as a starting material and a curing agent or cosmetic formulated with ceramide
JP2002003378A (en) * 2000-06-22 2002-01-09 Kanebo Ltd External antipruritic agent
JP2005002324A (en) * 2003-03-19 2005-01-06 Fisheries Research Agency Method for producing sphingolipids from aquatic organisms
JPWO2004009041A1 (en) * 2002-07-22 2005-12-08 辻製油株式会社 Skin cosmetic composition
WO2007034927A1 (en) * 2005-09-22 2007-03-29 Snow Brand Milk Products Co., Ltd. Medicine, food and drink or feed containing sphingomyelin
JP2007112793A (en) * 2005-09-22 2007-05-10 Snow Brand Milk Prod Co Ltd Sphingomyelin-containing medicine, food or drink or feed
JP2012167104A (en) * 2005-09-22 2012-09-06 Snow Brand Milk Products Co Ltd Sphingomyelin-containing medicine
JP2018524286A (en) * 2015-05-22 2018-08-30 バイオイベリカ ソシエダッド アノニマ Process for preparing animal brain extracts

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163888A (en) * 1984-02-03 1985-08-26 Pola Chem Ind Inc Production of lipid component
JPS60163806A (en) * 1984-02-03 1985-08-26 Pola Chem Ind Inc Skin pharmaceutical for external use
JPS61260008A (en) * 1985-05-15 1986-11-18 Sunstar Inc Cosmetic composition
JPS61271205A (en) * 1985-05-24 1986-12-01 Kanebo Ltd Skin cosmetic
JPS61286307A (en) * 1985-06-13 1986-12-16 Kanebo Ltd Skin cosmetic
JPS6256414A (en) * 1985-09-06 1987-03-12 Noebia:Kk Cosmetic

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163888A (en) * 1984-02-03 1985-08-26 Pola Chem Ind Inc Production of lipid component
JPS60163806A (en) * 1984-02-03 1985-08-26 Pola Chem Ind Inc Skin pharmaceutical for external use
JPS61260008A (en) * 1985-05-15 1986-11-18 Sunstar Inc Cosmetic composition
JPS61271205A (en) * 1985-05-24 1986-12-01 Kanebo Ltd Skin cosmetic
JPS61286307A (en) * 1985-06-13 1986-12-16 Kanebo Ltd Skin cosmetic
JPS6256414A (en) * 1985-09-06 1987-03-12 Noebia:Kk Cosmetic

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2692781A1 (en) * 1992-06-24 1993-12-31 Sederma Sa Cosmetic compsn., for improving skin - contains sphingomyelin(s) of milk or fish as natural precursor ceramide(s), avoiding use of sphingo:lipid(s) from mammals, esp. cattle
JPH06179613A (en) * 1992-12-12 1994-06-28 Taiyo Kagaku Co Ltd Cosmetics
JPH06199627A (en) * 1992-12-26 1994-07-19 Taiyo Kagaku Co Ltd Cosmetics
JPH08506811A (en) * 1993-02-11 1996-07-23 スベンスカ、メジェリールナス、リクスフェレニング、エコノミー、アクチェボラーグ Sphingomyelin extraction method
AU675116B2 (en) * 1993-02-11 1997-01-23 Svenska Mejeriernas Riksforening Ekonomi Ab Method for extracting sphingomyelin from phospholipid con taining fat concentrate
JPH08217666A (en) * 1995-02-10 1996-08-27 Mikimoto Pharmaceut Co Ltd Oil-in-water type cream base
US5912152A (en) * 1995-02-28 1999-06-15 Yakurigaku Chuo Kenkyusho Process for preparing sphingomyelin and ceramide from erythrocyte as a starting material and a curing agent or cosmetic formulated with ceramide
FR2752526A1 (en) * 1996-08-26 1998-02-27 Dong Kook Pharm Co Ltd ANTIHEMOLYTIC LIPOSOMAL PREPARATION
JP2002003378A (en) * 2000-06-22 2002-01-09 Kanebo Ltd External antipruritic agent
JPWO2004009041A1 (en) * 2002-07-22 2005-12-08 辻製油株式会社 Skin cosmetic composition
JP2005002324A (en) * 2003-03-19 2005-01-06 Fisheries Research Agency Method for producing sphingolipids from aquatic organisms
WO2007034927A1 (en) * 2005-09-22 2007-03-29 Snow Brand Milk Products Co., Ltd. Medicine, food and drink or feed containing sphingomyelin
JP2007112793A (en) * 2005-09-22 2007-05-10 Snow Brand Milk Prod Co Ltd Sphingomyelin-containing medicine, food or drink or feed
JP2012167104A (en) * 2005-09-22 2012-09-06 Snow Brand Milk Products Co Ltd Sphingomyelin-containing medicine
US9186366B2 (en) 2005-09-22 2015-11-17 Megmilk Snow Brand Co., Ltd. Medicine, food and drink or feed containing sphingomyelin
JP2018524286A (en) * 2015-05-22 2018-08-30 バイオイベリカ ソシエダッド アノニマ Process for preparing animal brain extracts

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