JPS6422853A - Nucleoside analog - Google Patents

Nucleoside analog

Info

Publication number
JPS6422853A
JPS6422853A JP17723487A JP17723487A JPS6422853A JP S6422853 A JPS6422853 A JP S6422853A JP 17723487 A JP17723487 A JP 17723487A JP 17723487 A JP17723487 A JP 17723487A JP S6422853 A JPS6422853 A JP S6422853A
Authority
JP
Japan
Prior art keywords
adenine
amino
compound
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17723487A
Other languages
Japanese (ja)
Inventor
Yasushi Matsumura
Yoshitomi Morisawa
Arata Yasuda
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP17723487A priority Critical patent/JPS6422853A/en
Publication of JPS6422853A publication Critical patent/JPS6422853A/en
Pending legal-status Critical Current

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  • Pyridine Compounds (AREA)

Abstract

NEW MATERIAL:A compound of the formula (B is residue of nucleic acid base). EXAMPLE:9-[2,3-Dideoxy-4a-(hydroxymethyl)-2-cyclopentene-1a-yl]adenine. USE:Antitumor agent, antiviral or agrochemicals. PREPARATION:For example, in the preparation of adenosine, the reaction of 5-amino-4,6-dichloropyrimidine with cis-4-amino-2-cyclopentanemethanol gives a diaminopyrimidine derivative, then ethyl orthoformate is used to form the purine skeleton, further the chlorine atom in the 6-position of the purine ring is treated with ammonia to convert into adenine to give the compound of the formula.
JP17723487A 1987-07-17 1987-07-17 Nucleoside analog Pending JPS6422853A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17723487A JPS6422853A (en) 1987-07-17 1987-07-17 Nucleoside analog

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17723487A JPS6422853A (en) 1987-07-17 1987-07-17 Nucleoside analog

Publications (1)

Publication Number Publication Date
JPS6422853A true JPS6422853A (en) 1989-01-25

Family

ID=16027498

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17723487A Pending JPS6422853A (en) 1987-07-17 1987-07-17 Nucleoside analog

Country Status (1)

Country Link
JP (1) JPS6422853A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034394A (en) * 1988-06-27 1991-07-23 Burroughs Wellcome Co. Therapeutic nucleosides
WO1991015489A1 (en) * 1990-04-06 1991-10-17 Glaxo Inc. Process for the synthesis of cyclopentene derivatives
WO1991015490A1 (en) * 1990-04-06 1991-10-17 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5922694A (en) * 1988-01-20 1999-07-13 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
JP2008515962A (en) * 2004-10-12 2008-05-15 グレンマーク・ファーマシューティカルズ・エスエー Novel dipeptidyl peptidase IV inhibitors, pharmaceutical compositions containing them, and processes for preparing them

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922694A (en) * 1988-01-20 1999-07-13 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5962684A (en) * 1988-01-20 1999-10-05 Regents Of The University Of Minnesota Method of preparation of dideoxycarbocyclic nucleosides
US6072053A (en) * 1988-01-20 2000-06-06 Univ Minnesota Dideoxycarbocyclic nucleosides
US5034394A (en) * 1988-06-27 1991-07-23 Burroughs Wellcome Co. Therapeutic nucleosides
US5049671A (en) * 1988-06-27 1991-09-17 Burroughs Wellcome Co. 6-substituted purine carbocyclic nucleosides
WO1991015489A1 (en) * 1990-04-06 1991-10-17 Glaxo Inc. Process for the synthesis of cyclopentene derivatives
WO1991015490A1 (en) * 1990-04-06 1991-10-17 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5144034A (en) * 1990-04-06 1992-09-01 Glaxo Inc. Process for the synthesis of cyclopentene derivatives of purines
JP2008515962A (en) * 2004-10-12 2008-05-15 グレンマーク・ファーマシューティカルズ・エスエー Novel dipeptidyl peptidase IV inhibitors, pharmaceutical compositions containing them, and processes for preparing them

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