JPS6429363A - Heterocyclic derivative - Google Patents

Heterocyclic derivative

Info

Publication number
JPS6429363A
JPS6429363A JP62184864A JP18486487A JPS6429363A JP S6429363 A JPS6429363 A JP S6429363A JP 62184864 A JP62184864 A JP 62184864A JP 18486487 A JP18486487 A JP 18486487A JP S6429363 A JPS6429363 A JP S6429363A
Authority
JP
Japan
Prior art keywords
compound
formula
heterocyclic derivative
action
propylacetophenone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62184864A
Other languages
Japanese (ja)
Inventor
Toshio Hamazaki
Michio Terasawa
Takanori Oe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Yoshitomi Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical Industries Ltd filed Critical Yoshitomi Pharmaceutical Industries Ltd
Priority to JP62184864A priority Critical patent/JPS6429363A/en
Publication of JPS6429363A publication Critical patent/JPS6429363A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I [Ar is pyridine ring or quinoline ring; X is single bond, (CH2)l or CH=CH; l is 1 or 2; Y is OR<1> or NR<2>R<3>; R<1>-R<3> are H or 1-6C straight or branched chain alkyl; R<2>-R<3> may be lower alkenyl, cycloalkyl, lower hydroxyalkyl, dialkylamino(lower alkyl), (substituted) aryl or aralkyl, etc.] and its salts. EXAMPLE:6-( 4-Acetyl-3-hydroxy-2-propylphenoxy ) methylpyridine-2-carboxylic acid ethyl ester. USE:A drug having strong leucotriene-antagonistic action and coronary vasodilating action or its intermediate. PREPARATION:The compound of formula I can be produced by reacting a compound of formula II (Z is reactive atom or group such as Cl) with 2,4- dihydroxy-3-propylacetophenone and, as necessary, hydrolyzing the reaction product.
JP62184864A 1987-07-23 1987-07-23 Heterocyclic derivative Pending JPS6429363A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62184864A JPS6429363A (en) 1987-07-23 1987-07-23 Heterocyclic derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62184864A JPS6429363A (en) 1987-07-23 1987-07-23 Heterocyclic derivative

Publications (1)

Publication Number Publication Date
JPS6429363A true JPS6429363A (en) 1989-01-31

Family

ID=16160645

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62184864A Pending JPS6429363A (en) 1987-07-23 1987-07-23 Heterocyclic derivative

Country Status (1)

Country Link
JP (1) JPS6429363A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021576A (en) * 1989-10-27 1991-06-04 American Home Products Corporation 2-Anilino phenylacetic acid derivatives
US5225422A (en) * 1991-05-31 1993-07-06 Sumitomo Pharmaceuticals Co., Ltd. Pyridine compounds which are useful as leukotriene b4 antagonist

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021576A (en) * 1989-10-27 1991-06-04 American Home Products Corporation 2-Anilino phenylacetic acid derivatives
US5225422A (en) * 1991-05-31 1993-07-06 Sumitomo Pharmaceuticals Co., Ltd. Pyridine compounds which are useful as leukotriene b4 antagonist

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