JPS6430A - Gradually releasing preparation - Google Patents

Gradually releasing preparation

Info

Publication number
JPS6430A
JPS6430A JP63068678A JP6867888A JPS6430A JP S6430 A JPS6430 A JP S6430A JP 63068678 A JP63068678 A JP 63068678A JP 6867888 A JP6867888 A JP 6867888A JP S6430 A JPS6430 A JP S6430A
Authority
JP
Japan
Prior art keywords
active ingredients
adenine
certain time
layer
cystine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63068678A
Other languages
Japanese (ja)
Other versions
JP2638604B2 (en
JPH0130A (en
Inventor
Yoshimitsu Iida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP6867888A priority Critical patent/JP2638604B2/en
Publication of JPS6430A publication Critical patent/JPS6430A/en
Publication of JPH0130A publication Critical patent/JPH0130A/en
Application granted granted Critical
Publication of JP2638604B2 publication Critical patent/JP2638604B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To provide the subject preparation in which the active components can release gradually or after a certain time by adding adenine, cystine or tyrosine to active ingredients.
CONSTITUTION: The active ingredients, excipients such as lactic acid, mannitol or hardened oil, and at least one selected from adenine, cystine or tyrosine are mixed to give the subject preparation. The content of adenine and such is over 2wt.%, preferably over 5wt.% based on the total weight of the composition. When the solubility in water of the active ingredients is less than 0.1%, they are crushed into particles of average particle size less than 10μm and combined with lower substituted hydroxypropylcellulose and hydroxypropylcellulose. The layer containing the active ingredients and the other layer not containing are laminated, compressed to give tablets with increased releasability of the active ingredients after a certain time. Or granules which can release the active ingredients after a certain time is prepared by coating the rapidly releasing preparation with a layer of adenine or such.
COPYRIGHT: (C)1989,JPO&Japio
JP6867888A 1987-03-24 1988-03-23 Sustained release formulation Expired - Fee Related JP2638604B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6867888A JP2638604B2 (en) 1987-03-24 1988-03-23 Sustained release formulation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6967787 1987-03-24
JP62-69677 1987-03-24
JP6867888A JP2638604B2 (en) 1987-03-24 1988-03-23 Sustained release formulation

Publications (3)

Publication Number Publication Date
JPS6430A true JPS6430A (en) 1989-01-05
JPH0130A JPH0130A (en) 1989-01-05
JP2638604B2 JP2638604B2 (en) 1997-08-06

Family

ID=26409883

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6867888A Expired - Fee Related JP2638604B2 (en) 1987-03-24 1988-03-23 Sustained release formulation

Country Status (1)

Country Link
JP (1) JP2638604B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059552A1 (en) * 1998-05-15 1999-11-25 Chugai Seiyaku Kabushiki Kaisha Regulated release preparations
WO2008149668A1 (en) * 2007-06-07 2008-12-11 Kobayashi Pharmaceutical Co., Ltd. Protein-containing composition
WO2011004799A1 (en) 2009-07-06 2011-01-13 杏林製薬株式会社 Tablet having hollow structure
KR101111456B1 (en) * 2010-03-12 2012-02-22 (주)경신이엔지 Clamp for a solar cell plate
JP2022529189A (en) * 2019-04-19 2022-06-17 ホフマン・テクノロジーズ・エルエルシー Sustained release formulation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059552A1 (en) * 1998-05-15 1999-11-25 Chugai Seiyaku Kabushiki Kaisha Regulated release preparations
JP5048177B2 (en) * 1998-05-15 2012-10-17 中外製薬株式会社 Controlled release formulation
WO2008149668A1 (en) * 2007-06-07 2008-12-11 Kobayashi Pharmaceutical Co., Ltd. Protein-containing composition
JP2008303176A (en) * 2007-06-07 2008-12-18 Kobayashi Pharmaceut Co Ltd Protein-containing composition
WO2011004799A1 (en) 2009-07-06 2011-01-13 杏林製薬株式会社 Tablet having hollow structure
KR101111456B1 (en) * 2010-03-12 2012-02-22 (주)경신이엔지 Clamp for a solar cell plate
JP2022529189A (en) * 2019-04-19 2022-06-17 ホフマン・テクノロジーズ・エルエルシー Sustained release formulation

Also Published As

Publication number Publication date
JP2638604B2 (en) 1997-08-06

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees