JPS644629A - Collagen sponge - Google Patents

Collagen sponge

Info

Publication number
JPS644629A
JPS644629A JP62159494A JP15949487A JPS644629A JP S644629 A JPS644629 A JP S644629A JP 62159494 A JP62159494 A JP 62159494A JP 15949487 A JP15949487 A JP 15949487A JP S644629 A JPS644629 A JP S644629A
Authority
JP
Japan
Prior art keywords
collagen
active agent
surface active
mixture
isoelectric point
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62159494A
Other languages
Japanese (ja)
Other versions
JPH0788433B2 (en
Inventor
Takeshi Hayade
Toshio Fujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPI COLLAGEN KOGYO KK
NIPPI KORAAGEN KOGYO KK
Original Assignee
NIPPI COLLAGEN KOGYO KK
NIPPI KORAAGEN KOGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPI COLLAGEN KOGYO KK, NIPPI KORAAGEN KOGYO KK filed Critical NIPPI COLLAGEN KOGYO KK
Priority to JP62159494A priority Critical patent/JPH0788433B2/en
Publication of JPS644629A publication Critical patent/JPS644629A/en
Publication of JPH0788433B2 publication Critical patent/JPH0788433B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Cigarettes, Filters, And Manufacturing Of Filters (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

PURPOSE:To obtain the title sponge having pores of a uniform pore direction and a uniform pore diameter as desired and excellent in air-permeability, water absorption, adsorbability, flexibility, elasticity and blood coagulating property, by adding a given amt. of a surface active agent to an aq. collagen soln. and freeze-drying the mixture. CONSTITUTION:An aq. soln. of collagen of a concn. of 0.05-10% is dispersed homogeneously with its pH adjusted as suitable for each collagen, e.g., to a pH of 2.0-3.5 and 5.0-12.0 for the collagen having an isoelectric point of 4.0-4.5, to a pH of 2.0-4.0 and 6.5-12.0 for the collagen having an isoelectric point of 4.5-5.5, or to a pH of 2.0-5.5 and 10.0-12.0 for the collagen having an isoelectric point of 7.0-9.5. To this dispersion is added a surface active agent (e.g., a nonionic surface active agent of an HLB value of 1.8-40) by 0.1-100% of the dry wt. of the collagen, and the mixture is poured in 5-100mm thickness into a tray, freezed and then freeze-dried to give the title open-cell sponge having pore diameters of 10-1,000mu, with the pores being formed in the same direction as that of the thickness of the mixture and the pore diameters being in a certain range corresponding to the content of the surface active agent.
JP62159494A 1987-06-26 1987-06-26 Collagen sponge Expired - Fee Related JPH0788433B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62159494A JPH0788433B2 (en) 1987-06-26 1987-06-26 Collagen sponge

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62159494A JPH0788433B2 (en) 1987-06-26 1987-06-26 Collagen sponge

Publications (2)

Publication Number Publication Date
JPS644629A true JPS644629A (en) 1989-01-09
JPH0788433B2 JPH0788433B2 (en) 1995-09-27

Family

ID=15694994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62159494A Expired - Fee Related JPH0788433B2 (en) 1987-06-26 1987-06-26 Collagen sponge

Country Status (1)

Country Link
JP (1) JPH0788433B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0341952A (en) * 1989-07-11 1991-02-22 Nippon Zeon Co Ltd wound dressing
WO2008001952A1 (en) * 2006-06-30 2008-01-03 Kyoto University Thin film multilocular structure comprising collagen, material for tissue regeneration containing the same and method for producing the same
WO2018123814A1 (en) * 2016-12-28 2018-07-05 株式会社高研 High-strength collagen sponge
US10219895B2 (en) 2012-10-26 2019-03-05 Wake Forest University Health Sciences Nanofiber-based graft for heart valve replacement and methods of using the same
US10632235B2 (en) 2007-10-10 2020-04-28 Wake Forest University Health Sciences Devices and methods for treating spinal cord tissue

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0341952A (en) * 1989-07-11 1991-02-22 Nippon Zeon Co Ltd wound dressing
WO2008001952A1 (en) * 2006-06-30 2008-01-03 Kyoto University Thin film multilocular structure comprising collagen, material for tissue regeneration containing the same and method for producing the same
JP5142219B2 (en) * 2006-06-30 2013-02-13 国立大学法人京都大学 Thin film multituft structure made of collagen, tissue regeneration member containing the same, and method for producing them
US8388692B2 (en) 2006-06-30 2013-03-05 Kyoto University Thin film multilocular structure made of collagen, member for tissue regeneration containing the same, and method for producing the same
US8709095B2 (en) 2006-06-30 2014-04-29 Kyoto University Thin film multilocular structure made of collagen, member for tissue regeneration containing the same, and method for producing the same
US10632235B2 (en) 2007-10-10 2020-04-28 Wake Forest University Health Sciences Devices and methods for treating spinal cord tissue
US10219895B2 (en) 2012-10-26 2019-03-05 Wake Forest University Health Sciences Nanofiber-based graft for heart valve replacement and methods of using the same
WO2018123814A1 (en) * 2016-12-28 2018-07-05 株式会社高研 High-strength collagen sponge
JPWO2018123814A1 (en) * 2016-12-28 2020-01-09 株式会社高研 High strength collagen sponge

Also Published As

Publication number Publication date
JPH0788433B2 (en) 1995-09-27

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Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

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LAPS Cancellation because of no payment of annual fees