JPS6450877A - Oxygen radical catching and removing agent - Google Patents
Oxygen radical catching and removing agentInfo
- Publication number
- JPS6450877A JPS6450877A JP62207236A JP20723687A JPS6450877A JP S6450877 A JPS6450877 A JP S6450877A JP 62207236 A JP62207236 A JP 62207236A JP 20723687 A JP20723687 A JP 20723687A JP S6450877 A JPS6450877 A JP S6450877A
- Authority
- JP
- Japan
- Prior art keywords
- baicalein
- purified water
- agent
- scutellaria baicalensis
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 4
- 229910052760 oxygen Inorganic materials 0.000 title abstract 3
- 239000001301 oxygen Substances 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- FXNFHKRTJBSTCS-UHFFFAOYSA-N Baicalein Natural products C=1C(=O)C=2C(O)=C(O)C(O)=CC=2OC=1C1=CC=CC=C1 FXNFHKRTJBSTCS-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 3
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 3
- UDFLTIRFTXWNJO-UHFFFAOYSA-N baicalein Chemical compound O1C2=CC(=O)C(O)=C(O)C2=C(O)C=C1C1=CC=CC=C1 UDFLTIRFTXWNJO-UHFFFAOYSA-N 0.000 abstract 3
- 229940015301 baicalein Drugs 0.000 abstract 3
- 238000000605 extraction Methods 0.000 abstract 3
- 239000008213 purified water Substances 0.000 abstract 3
- 230000003213 activating effect Effects 0.000 abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 2
- 239000000706 filtrate Substances 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 208000003351 Melanosis Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000004677 Nylon Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229940041181 antineoplastic drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229930003935 flavonoid Natural products 0.000 abstract 1
- 150000002215 flavonoids Chemical class 0.000 abstract 1
- 235000017173 flavonoids Nutrition 0.000 abstract 1
- 230000003779 hair growth Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000007654 immersion Methods 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 229920001778 nylon Polymers 0.000 abstract 1
- 230000037303 wrinkles Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE:To obtain the titled agent to be blended with a system of prescription of drug and cosmetic fields, having excellent cell activating ability and immune activating ability, catching and removing oxygen radicals, using baicalein. CONSTITUTION:An oxygen radical catching and removing agent comprising baicalein of flavonoid system contained in Scutellaria baicalensis or an extract containing the same. In extraction of baicalein, for example, powder of Scutellaria baicalensis is blended with purified water, previously immersed in the purified water at 50 deg.C for 3hr, an alcohol such as ethanol is added to the water, immersion extraction or extraction under heating is carried out to give filtrate, which is treated with nylon and filtered. 1pt.wt. filtrate is mixed with 2pts.wt. purified water to precipitate yellow essence powder, which is dried to give an extract of Scutellaria baicalensis. The agent can prevent and treat various cancers and suppress side effects by blending with other anti-cancer drugs and is effective for preventing stain, freckle and wrinkles in the form of application of outer use of cosmetic, prevents removal of hair and promotes hair growth and restoration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62207236A JPS6450877A (en) | 1987-08-20 | 1987-08-20 | Oxygen radical catching and removing agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62207236A JPS6450877A (en) | 1987-08-20 | 1987-08-20 | Oxygen radical catching and removing agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6450877A true JPS6450877A (en) | 1989-02-27 |
| JPH0434969B2 JPH0434969B2 (en) | 1992-06-09 |
Family
ID=16536477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62207236A Granted JPS6450877A (en) | 1987-08-20 | 1987-08-20 | Oxygen radical catching and removing agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6450877A (en) |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01128933A (en) * | 1987-11-12 | 1989-05-22 | Shiseido Co Ltd | Hyaluronidase inhibitor |
| JPH01128934A (en) * | 1987-11-12 | 1989-05-22 | Shiseido Co Ltd | Protease inhibitor |
| JPH0393782A (en) * | 1989-08-30 | 1991-04-18 | Pacific Chem Ind Co | Cell protective agent for protecting cell from activated oxygens and method of its preparation |
| JPH03240736A (en) * | 1990-02-16 | 1991-10-28 | Ichimaru Pharcos Co Ltd | Cell activating substance derived from sophora angustifolia sieb. et zucc. |
| JPH0656669A (en) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | Pterine derivative preparation having active oxygen-scavenging action |
| US5321632A (en) * | 1991-02-26 | 1994-06-14 | Nippon Telegraph And Telephone Corporation | Method and apparatus for measuring the length of a transmission line in accordance with a reflected waveform |
| JPH0725761A (en) * | 1993-07-09 | 1995-01-27 | Kureha Chem Ind Co Ltd | Cartilage protectant |
| JPH07187988A (en) * | 1993-12-27 | 1995-07-25 | Nagase & Co Ltd | Melanin production inhibitor, method for producing the same and whitening cosmetic containing the same |
| JPH10158146A (en) * | 1996-11-29 | 1998-06-16 | Nonogawa Shoji Kk | Skin preparation for external use |
| WO1998049256A1 (en) * | 1997-04-29 | 1998-11-05 | Lamer-Zarawska, Eliza | Natural antioxidant |
| JPH11292753A (en) * | 1998-04-14 | 1999-10-26 | Dowa Yakushou Kk | Agent for external use for head skin |
| JP2000319154A (en) * | 1999-05-06 | 2000-11-21 | Nippon Menaade Keshohin Kk | Phototoxicity inhibitor |
| JP2001122765A (en) * | 2000-09-28 | 2001-05-08 | Naris Cosmetics Co Ltd | Active oxygen scavenger and cosmetic |
| KR20020014451A (en) * | 2000-08-18 | 2002-02-25 | 김해관 | Sun-tan preventing makeup compositions having antioxidation effects |
| JP2003526658A (en) * | 2000-03-14 | 2003-09-09 | ポルテラ アンド コンパニーア ソシエダット アノニマ | Composition comprising an L-dopa kidney cell transfer inhibitor for the treatment of Parkinson's disease |
| EP1556031A4 (en) * | 2002-10-22 | 2009-03-25 | Jenken Biosciences Inc | Chromones and chromone derivatives and uses thereof |
| JP2009091355A (en) * | 2007-09-19 | 2009-04-30 | Noevir Co Ltd | Humectant, anti-aging agent, antioxidant agent, immunostimulator, skin-lightening agent, external preparation for skin and functional oral composition |
| US20130101616A1 (en) * | 2003-09-08 | 2013-04-25 | James Dao | Compositions of botanical extracts for cancer therapy |
| JP2014012645A (en) * | 2012-07-04 | 2014-01-23 | Kao Corp | Cuticle cell differentiation promoter |
| CN106999528A (en) * | 2014-10-06 | 2017-08-01 | 株式会社爱茉莉太平洋 | For preventing hair loss or stimulating the composition for including high mountain radix scutellariae extract of natural on-off cycles of hair growth |
| JP2018104319A (en) * | 2016-12-26 | 2018-07-05 | サンスター株式会社 | Hair growth composition |
-
1987
- 1987-08-20 JP JP62207236A patent/JPS6450877A/en active Granted
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01128933A (en) * | 1987-11-12 | 1989-05-22 | Shiseido Co Ltd | Hyaluronidase inhibitor |
| JPH01128934A (en) * | 1987-11-12 | 1989-05-22 | Shiseido Co Ltd | Protease inhibitor |
| JPH0393782A (en) * | 1989-08-30 | 1991-04-18 | Pacific Chem Ind Co | Cell protective agent for protecting cell from activated oxygens and method of its preparation |
| JPH03240736A (en) * | 1990-02-16 | 1991-10-28 | Ichimaru Pharcos Co Ltd | Cell activating substance derived from sophora angustifolia sieb. et zucc. |
| US5321632A (en) * | 1991-02-26 | 1994-06-14 | Nippon Telegraph And Telephone Corporation | Method and apparatus for measuring the length of a transmission line in accordance with a reflected waveform |
| JPH0656669A (en) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | Pterine derivative preparation having active oxygen-scavenging action |
| JPH0725761A (en) * | 1993-07-09 | 1995-01-27 | Kureha Chem Ind Co Ltd | Cartilage protectant |
| JPH07187988A (en) * | 1993-12-27 | 1995-07-25 | Nagase & Co Ltd | Melanin production inhibitor, method for producing the same and whitening cosmetic containing the same |
| JPH10158146A (en) * | 1996-11-29 | 1998-06-16 | Nonogawa Shoji Kk | Skin preparation for external use |
| WO1998049256A1 (en) * | 1997-04-29 | 1998-11-05 | Lamer-Zarawska, Eliza | Natural antioxidant |
| JPH11292753A (en) * | 1998-04-14 | 1999-10-26 | Dowa Yakushou Kk | Agent for external use for head skin |
| JP2000319154A (en) * | 1999-05-06 | 2000-11-21 | Nippon Menaade Keshohin Kk | Phototoxicity inhibitor |
| JP2003526658A (en) * | 2000-03-14 | 2003-09-09 | ポルテラ アンド コンパニーア ソシエダット アノニマ | Composition comprising an L-dopa kidney cell transfer inhibitor for the treatment of Parkinson's disease |
| KR20020014451A (en) * | 2000-08-18 | 2002-02-25 | 김해관 | Sun-tan preventing makeup compositions having antioxidation effects |
| JP2001122765A (en) * | 2000-09-28 | 2001-05-08 | Naris Cosmetics Co Ltd | Active oxygen scavenger and cosmetic |
| EP1556031A4 (en) * | 2002-10-22 | 2009-03-25 | Jenken Biosciences Inc | Chromones and chromone derivatives and uses thereof |
| US20130101616A1 (en) * | 2003-09-08 | 2013-04-25 | James Dao | Compositions of botanical extracts for cancer therapy |
| JP2009091355A (en) * | 2007-09-19 | 2009-04-30 | Noevir Co Ltd | Humectant, anti-aging agent, antioxidant agent, immunostimulator, skin-lightening agent, external preparation for skin and functional oral composition |
| JP2014012645A (en) * | 2012-07-04 | 2014-01-23 | Kao Corp | Cuticle cell differentiation promoter |
| CN106999528A (en) * | 2014-10-06 | 2017-08-01 | 株式会社爱茉莉太平洋 | For preventing hair loss or stimulating the composition for including high mountain radix scutellariae extract of natural on-off cycles of hair growth |
| JP2018104319A (en) * | 2016-12-26 | 2018-07-05 | サンスター株式会社 | Hair growth composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0434969B2 (en) | 1992-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bollag | Therapy of chemically induced skin tumors of mice with vitamin A palmitate and vitamin A acid | |
| NZ504026A (en) | Methods for treating hypercoagulable states or acquired protein C deficiency using human-activated protein C | |
| IL77062A0 (en) | Method and apparatus for removing immunosuppressive components from the blood of mammals | |
| KANTOR et al. | The difference in permeability of cartilage to cationic and anionic dyes | |
| EP0602686A3 (en) | Concentrates of mistletoe extract lectins and standardized compositions, stabilized of the corresponding mistletoe lectins, process for their preparation, as well as medicaments containing them and their use. | |
| ATE4115T1 (en) | 6-SUBSTITUTED 11-ALKYLENE-MORPHANTRIDINES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM. | |
| DE3369695D1 (en) | Aqueous polysiloxane dispersions, process for preparing them and their use in the treatment of textiles | |
| PT82848A (en) | NEW 11-STAGE-SUBSTITUTED 3,11-DIHYDRO-6H-OYRIDO- <2,3-B> <1,4> BENZODIAZEPINE-6-ONE METHOD FOR THE PRODUCTION THEREOF, AND THE MEDICAMENT CONTAINING SUCH COMPOUNDS | |
| HU9200015D0 (en) | Podofillotoxine preparation containing triglicerides | |
| CN108158912A (en) | A kind of milk thistle anti-acne repaiies trace gel and preparation method thereof | |
| JPH0725657B2 (en) | Hair treatment composition | |
| CA2103707A1 (en) | Treatment of non-small cell lung carcinoma | |
| JPS5557520A (en) | Preparation of carcinostatic substance | |
| Seidel et al. | Erythroid stem cell regeneration in normal and plethoric mice treated by cytosinarabinoside | |
| JPS6475428A (en) | Prophylactic and remedy for vibrio auldery in fishes | |
| ATE66375T1 (en) | USE OF INTERFERON-GAMMA (IFN-GAMMA) CONTAINING PREPARATIONS FOR THE SYSTEMIC TREATMENT OF VARIOUS HUMAN DISEASES AT LOW DOSES. | |
| DE69213886D1 (en) | VEGETABLE ANTINEOPLASTIC CHEMOTHERAPEUTIC, WITH HIGH SELECTIVITY AND VERY REDUCED TOXICITY, AND METHOD FOR THE PRODUCTION THEREOF | |
| Bedrak | Enzymic responses following administration of ACTH to birds | |
| JPS57206370A (en) | Preparation of healthy drink | |
| JPS5750921A (en) | Carcinostatic agent for oral administration | |
| Zhang et al. | Clinical evaluation of enoxacin | |
| JPS5621682A (en) | Filtering and sterilizing device | |
| Sasaki et al. | Antitumor activity of egg lectin from frog. II. Increase of antitumor activity of egg lectin from Rana japonica in temporary stop of regional blood circulation after intravenous injection (author's transl) | |
| Abdelbaset et al. | Effect of zomepirac sodium after acute and subacute treatments on male laboratory rats: Effects on nucleic acids. | |
| Gohji et al. | Anti-neoplastic activity of a human recombinant tumor necrosis factor (Hu-rec-TNF) alone or in combination with human recombinant gamma-interferon, doxorubicin or cis-platinum on a human renal cell carcinoma line |