JPS6450896A - Contraction suppressing peptide - Google Patents

Contraction suppressing peptide

Info

Publication number
JPS6450896A
JPS6450896A JP62207784A JP20778487A JPS6450896A JP S6450896 A JPS6450896 A JP S6450896A JP 62207784 A JP62207784 A JP 62207784A JP 20778487 A JP20778487 A JP 20778487A JP S6450896 A JPS6450896 A JP S6450896A
Authority
JP
Japan
Prior art keywords
formula
protecting group
amino
group
cha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62207784A
Other languages
Japanese (ja)
Inventor
Hideo Okai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanshin Chemical Industry Co Ltd
Original Assignee
Sanshin Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanshin Chemical Industry Co Ltd filed Critical Sanshin Chemical Industry Co Ltd
Priority to JP62207784A priority Critical patent/JPS6450896A/en
Publication of JPS6450896A publication Critical patent/JPS6450896A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:A peptideamide expressed by the formula [X is Gly, D(L)-Ala, D(L)-Asn, D(L)-Gln, etc.; CHA is cyclohexylamidated product of carboxyl group of amino acid.; n is 1 or 2; m is 0 or 1]. USE:A muscle contraction suppressing agent. PREPARATION:For example, the formula Z-Arg(NO2)-OH (Z is protecting group of amino group) activated in a solvent is reacted with the formula D-Ala- CHA.HCl and then the resultant compound is reduced with hydrogen in the presence of Pd-black and protecting group is removed to give the formula Arg-D-Ala-CHA, which is then dissolved in water and reacted with the formula Boc-Met-OH (Boc is protecting group of amino group) and the amino protecting group is removed and then the solution is reacted with the formula PMZ-Phe-OH (PMZ is protecting group of amino group) and amino protecting group is removed to provide the compound expressed by the formula.
JP62207784A 1987-08-20 1987-08-20 Contraction suppressing peptide Pending JPS6450896A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62207784A JPS6450896A (en) 1987-08-20 1987-08-20 Contraction suppressing peptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62207784A JPS6450896A (en) 1987-08-20 1987-08-20 Contraction suppressing peptide

Publications (1)

Publication Number Publication Date
JPS6450896A true JPS6450896A (en) 1989-02-27

Family

ID=16545448

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62207784A Pending JPS6450896A (en) 1987-08-20 1987-08-20 Contraction suppressing peptide

Country Status (1)

Country Link
JP (1) JPS6450896A (en)

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