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Mitsui Toatsu Chemicals Inc
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Mitsui Toatsu Chemicals Inc
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Priority to JP27751587ApriorityCriticalpatent/JPS6460393A/en
Publication of JPS6460393ApublicationCriticalpatent/JPS6460393A/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Abstract
PURPOSE:To obtain L-threonine useful as pharmaceutical and feed additive, using a fermentation process, by culturing a specific bacterial strain belonging to Bacillus genus and resistant to AHV in a nutrient medium. CONSTITUTION:A mutant resistant to AHV (alpha-amino-beta-hydroxyvaleric acid), i.e. OMT-3017 (FERM P-9344), OMT-3018 (FERM P-9650) or OMT-3019 (FERM P-9651) is prepared by the mutagenic treatment of Bacillus subtilis ATCC 6051, Bacillus licheniformis ATCC 14580 or Bacillus cereus ATCC 14579. The obtained strain is aerobically cultured in a medium added with carbon source, nitrogen, source, inorganic ion and, as necessary, organic minor nutrients, etc., at pH 6-8 and 25-45 deg.C for 24-120hr to obtain L-threonine.
JP27751587A1987-05-141987-11-04Production of l-threonine by fermentation
PendingJPS6460393A
(en)
BIOLOGICALLY CULTURE OF THE MICROORGANISM STREPTOMYCES ROSEOSPORUS NRRL 15998 AND A PROCEDURE FOR PREPARING ANTIBIOTIC EFFECTIVE A-21978C COMPLEX OR ANY OR CERO 'C' C 'C' 'C' FACTORS 'CO' FACTORS 'CO'