JPS6464653A - Visco-elastic fluid for operation of eye - Google Patents
Visco-elastic fluid for operation of eyeInfo
- Publication number
- JPS6464653A JPS6464653A JP63107739A JP10773988A JPS6464653A JP S6464653 A JPS6464653 A JP S6464653A JP 63107739 A JP63107739 A JP 63107739A JP 10773988 A JP10773988 A JP 10773988A JP S6464653 A JPS6464653 A JP S6464653A
- Authority
- JP
- Japan
- Prior art keywords
- contg
- soln
- polyethylene oxide
- methyl cellulose
- cornea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012530 fluid Substances 0.000 title 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 4
- 210000004087 cornea Anatomy 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Medicinal Preparation (AREA)
Abstract
PURPOSE: To protect the corneas without obscuring the vision of an operator at all and to simultaneously enable the washing the same by preparing a soln. contg. a specific concn. of hydroxypropyl methyl cellulose and polyethylene oxide in a physiologically equil. salt soln. CONSTITUTION: The soln. contg. about >=1% hydroxypropyl methyl cellulose and about >=100ppm polyethylene oxide in the physiologically equil. salt soln. is prepd. as a viscoelastic aq./corpus vitreum substitute for an eye operation. The substitute is used in a method for washing and protecting the cornea tissues during the eye operation. This method includes steps of coating the inner cornea with the physiological salt soln. contg. about 2% hydrxpyropyl methyl cellulose and about 100ppm polyethylene oxide and simultaneously, periodically wetting the outer cornea with the adaptable physiological salt soln. contg. about half the hydroxypropyl methyl cellulose and about twice the polyethylene oxide.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4532687A | 1987-05-04 | 1987-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6464653A true JPS6464653A (en) | 1989-03-10 |
Family
ID=21937238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63107739A Pending JPS6464653A (en) | 1987-05-04 | 1988-05-02 | Visco-elastic fluid for operation of eye |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0359766A4 (en) |
| JP (1) | JPS6464653A (en) |
| AU (1) | AU1726088A (en) |
| CA (1) | CA1317226C (en) |
| GB (1) | GB2204238A (en) |
| WO (1) | WO1988008709A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008308503A (en) * | 2000-12-20 | 2008-12-25 | Alcon Inc | Intraocular irrigating solution having improved flow characteristics |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4020623C2 (en) * | 1990-06-29 | 1996-06-05 | Mezotraslevoj Nt Kompleks Mikr | Corneal protector and method for its production |
| CA2161774C (en) * | 1993-04-30 | 2000-01-04 | Nestle S.A. | Synthetic viscoelastic material for ophthalmic applications |
| RU2115413C1 (en) * | 1997-03-03 | 1998-07-20 | Малое государственное предприятие "Научно-экспериментальное производство" | Irrigation solution "intrasol" |
| EP1132065A1 (en) * | 2000-03-07 | 2001-09-12 | Gerrit Reinold Jacob Melles | Coloured visco-elastic composition |
| AU2002228955B2 (en) | 2000-12-20 | 2005-09-29 | Alcon Inc. | Solution for removing cataracts via liquefracture |
| US7084130B2 (en) | 2001-12-11 | 2006-08-01 | Alcon, Inc. | Intraocular irrigating solution having improved flow characteristics |
| TWI544922B (en) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | High concentration europart ingot ophthalmic composition |
| CN105749360B (en) * | 2016-03-28 | 2019-06-18 | 赛克赛斯生物科技股份有限公司 | A kind of composition and the preparation method and application thereof for protecting cornea |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1340517A (en) * | 1969-12-01 | 1973-12-12 | Burton Parsons Chemicals Inc | Ophthalmic solution |
| US3856919A (en) * | 1970-06-08 | 1974-12-24 | Burton Parsons Chemicals Inc | Ophthalmic solution |
| US3947573A (en) * | 1969-12-01 | 1976-03-30 | Burton, Parsons And Company, Inc. | Opthalmic solution |
| NL188266C (en) * | 1975-07-29 | 1992-05-18 | Merck & Co Inc | PROCESS FOR THE PREPARATION OF AN ORGANIC IMPLANT. |
| US4287175A (en) * | 1978-06-22 | 1981-09-01 | Merck & Co., Inc. | Contact lens wetting agents |
| US4629623A (en) * | 1984-06-11 | 1986-12-16 | Biomatrix, Inc. | Hyaluronate-poly (ethylene oxide) compositions and cosmetic formulations thereof |
| GB2167300B (en) * | 1984-11-23 | 1988-11-23 | Fisons Plc | Formulations |
-
1988
- 1988-03-30 CA CA000562926A patent/CA1317226C/en not_active Expired - Fee Related
- 1988-04-15 GB GB08808983A patent/GB2204238A/en not_active Withdrawn
- 1988-04-27 WO PCT/US1988/001389 patent/WO1988008709A1/en not_active Ceased
- 1988-04-27 AU AU17260/88A patent/AU1726088A/en not_active Abandoned
- 1988-04-27 EP EP19880904341 patent/EP0359766A4/en not_active Withdrawn
- 1988-05-02 JP JP63107739A patent/JPS6464653A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008308503A (en) * | 2000-12-20 | 2008-12-25 | Alcon Inc | Intraocular irrigating solution having improved flow characteristics |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2204238A (en) | 1988-11-09 |
| CA1317226C (en) | 1993-05-04 |
| EP0359766A1 (en) | 1990-03-28 |
| WO1988008709A1 (en) | 1988-11-17 |
| EP0359766A4 (en) | 1990-12-19 |
| AU1726088A (en) | 1988-12-06 |
| GB8808983D0 (en) | 1988-05-18 |
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