JPS6470476A - Production of isoxazoline derivative and/or isoxazole derivative - Google Patents
Production of isoxazoline derivative and/or isoxazole derivativeInfo
- Publication number
- JPS6470476A JPS6470476A JP22806487A JP22806487A JPS6470476A JP S6470476 A JPS6470476 A JP S6470476A JP 22806487 A JP22806487 A JP 22806487A JP 22806487 A JP22806487 A JP 22806487A JP S6470476 A JPS6470476 A JP S6470476A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- expressed
- formula
- reacted
- isoxazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000002545 isoxazoles Chemical class 0.000 title abstract 2
- 150000002547 isoxazolines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- 125000001559 cyclopropyl group Chemical class [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 2
- -1 nitrosonium tetrafluoroborate Chemical compound 0.000 abstract 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 1
- 229910004064 NOBF4 Inorganic materials 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910002091 carbon monoxide Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006552 photochemical reaction Methods 0.000 abstract 1
- 239000003504 photosensitizing agent Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PURPOSE:To industrially and advantageously obtain the titled compound useful as an antimicrobial agent, by reacting a readily available cyclopropane derivative as a raw material with nitrosonium tetrafluoroborate. CONSTITUTION:A cyclopropane derivative expressed by formula II (R<1> and R<2> are aromatic substituent group) is reacted with nitrosonium tetrafluoroborate (NOBF4), preferably in an aprotic polar solvent, such as acetonitrile or dichloromethane, normally at 0-100 deg.C, preferably at 10-40 deg.C to afford the aimed compound expressed by formula II and/or isoxazole derivative expressed by formula III. Furthermore, as an alternative method, the compound expressed by formula I is reacted with carbon monoxide in the presence of a photosensitizer while being irradiated with ultraviolet rays to provide the compounds expressed by formulas II and III. The wavelength of light for the above-mentioned photochemical reaction is preferably within the range of 250-500nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22806487A JPS6470476A (en) | 1987-09-10 | 1987-09-10 | Production of isoxazoline derivative and/or isoxazole derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22806487A JPS6470476A (en) | 1987-09-10 | 1987-09-10 | Production of isoxazoline derivative and/or isoxazole derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6470476A true JPS6470476A (en) | 1989-03-15 |
Family
ID=16870628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22806487A Pending JPS6470476A (en) | 1987-09-10 | 1987-09-10 | Production of isoxazoline derivative and/or isoxazole derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6470476A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR19990011062A (en) * | 1997-07-21 | 1999-02-18 | 손욱 | Ixoxazolidine ring-containing liquid crystal compound and liquid crystal composition containing the same |
-
1987
- 1987-09-10 JP JP22806487A patent/JPS6470476A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR19990011062A (en) * | 1997-07-21 | 1999-02-18 | 손욱 | Ixoxazolidine ring-containing liquid crystal compound and liquid crystal composition containing the same |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4898654A (en) | Method of producing optically active β-lactam derivatives | |
| PL242009A1 (en) | Process for preparing 1,4-diketopyrrole/3,4-c/pyrroles | |
| JPS646238A (en) | Production of carboxylic amides or esters | |
| SE8406138D0 (en) | NEW RETINOIDE | |
| DE69222183D1 (en) | 22-OXACHOLECALZIFEROL DERIVATIVES AND THEIR PRODUCTION | |
| Okazaki et al. | Synthesis and Reactions of o-Benzothioquinonemethides | |
| ES8304971A1 (en) | Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives. | |
| JPS5699450A (en) | Preparation of n-acyl-n-substituted formamide derivative | |
| SE8401996L (en) | PROCEDURE FOR PRODUCING QUINONS | |
| JPS5622761A (en) | Novel 2,2'-bis(4-cumylphenol)derivative | |
| Schantl et al. | Novel synthesis of n, n'-bis (α-isocyanato alkyl) diazenes | |
| DE3264063D1 (en) | Process for the preparation of alpha-dicyano-trimethylsilyloxy compounds | |
| ES483249A1 (en) | Process for the preparation of dicyclopentylene [2,2'-bis(4-alkyl-6-t-butylphenols)] | |
| Pasto et al. | Self-induced, photochemical, singlet-oxygen oxidation of 4-nitrobenzenesulfenates to 4-nitrobenzenesulfinates | |
| JPS54144348A (en) | Preparation of ketone derivative | |
| Fujihara et al. | A new double bond bridged dibenzodithiocin: Preparation, characterization, and its transannular pπ-(> S+ S+) interaction | |
| HUT48593A (en) | Process for producing asymmetric 1,4-dihydropyridinecarboxylic acid esters | |
| JPS6450848A (en) | Diaminoindane derivative and production thereof | |
| Bird et al. | The dehydrochlorination of succinyl chlorides | |
| Eichner et al. | The photochemistry of 2, 3, 11, 12-tetraphenyl-2, 3, 11, 12-didehydro-18-crown-6 | |
| EP0739885A4 (en) | PROCESS FOR PRODUCING 3-ISOXAZOLECARBOXYLIC ACID | |
| JPS577438A (en) | Production of acid chloride | |
| JPS5726686A (en) | Preparation of indole derivative | |
| ATE60058T1 (en) | ONE-STEP PROCESS FOR THE PREPARATION OF MIXED SUBSTITUTE 1,2-DI-ACYL-SN-GLYCERO-3-PHOSPHOCHOLINES. | |
| SU1634669A1 (en) | Process for preparing 4-amino-5-tosyl-imidazo (1,2:1,6) pyrido (2,3) pyrazine |