JPS6471493A - Rat il-1beta gene - Google Patents
Rat il-1beta geneInfo
- Publication number
- JPS6471493A JPS6471493A JP22931087A JP22931087A JPS6471493A JP S6471493 A JPS6471493 A JP S6471493A JP 22931087 A JP22931087 A JP 22931087A JP 22931087 A JP22931087 A JP 22931087A JP S6471493 A JPS6471493 A JP S6471493A
- Authority
- JP
- Japan
- Prior art keywords
- rat
- 1beta
- gene
- dna
- separating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101001076393 Rattus norvegicus Interleukin-1 beta Proteins 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 239000013600 plasmid vector Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE:To obtain a gene having a specific amino acid sequence and coding rat IL-1beta. CONSTITUTION:Rat IL-1beta is produced in a mass by a genetic engineering technique using a gene having an amino acid sequence of formula. The gene can be produced by preparing a DNA from an mRNA derived from a rat IL-1beta- producing cell, connecting the DNA to a proper vector such as plasmid vector of Escherichia coli, proliferating in a microbial cell, separating a clone capable of expressing rat IL-1beta and separating a DNA obtained by inserting the separated clone into a plasmid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22931087A JPS6471493A (en) | 1987-09-11 | 1987-09-11 | Rat il-1beta gene |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22931087A JPS6471493A (en) | 1987-09-11 | 1987-09-11 | Rat il-1beta gene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6471493A true JPS6471493A (en) | 1989-03-16 |
Family
ID=16890134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22931087A Pending JPS6471493A (en) | 1987-09-11 | 1987-09-11 | Rat il-1beta gene |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6471493A (en) |
-
1987
- 1987-09-11 JP JP22931087A patent/JPS6471493A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| J.IMMUNOL.=1986 * |
| NUCLEIC ACIDS RES.=1986 * |
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