JPS6479183A - Pyrrolo(2,3-d)pyrimidine derivative - Google Patents

Pyrrolo(2,3-d)pyrimidine derivative

Info

Publication number
JPS6479183A
JPS6479183A JP20274888A JP20274888A JPS6479183A JP S6479183 A JPS6479183 A JP S6479183A JP 20274888 A JP20274888 A JP 20274888A JP 20274888 A JP20274888 A JP 20274888A JP S6479183 A JPS6479183 A JP S6479183A
Authority
JP
Japan
Prior art keywords
pyrrolo
lower alkyl
oxo
pyrimidine
pyrimidine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP20274888A
Other languages
Japanese (ja)
Other versions
JPH085887B2 (en
Inventor
Keiichi Yokoyama
Takumi Kitahara
Suiji Katou
Kazutaka Tsuru
Akira Awaya
Takuo Nakano
Kazutoshi Horigome
Tadayuki Sasaki
Akira Mizuchi
Akira Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Petrochemical Industries Ltd
Original Assignee
Mitsui Petrochemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Petrochemical Industries Ltd filed Critical Mitsui Petrochemical Industries Ltd
Priority to JP20274888A priority Critical patent/JPH085887B2/en
Publication of JPS6479183A publication Critical patent/JPS6479183A/en
Publication of JPH085887B2 publication Critical patent/JPH085887B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NEW MATERIAL:A 2-piperazino-6-oxo(7H)pyrrolo[2,3-d]pyrimidine derivative expressed by formula I (R<1> is H, benzyl, lower acyl, lower alkoxycarbonyl or 3,4-methylenedioxyphenylmethyl; R<2> is H, lower alkyl, lower alkoxyl- substituted lower alkyl; R<3> is H, lower alkyl or lower akoxycarbonylmethyl; R<4> and R<5> are H or lower alkyl, provided that at least one of R<3>-R<5> is a group other than H or R<1> is a group other than H or benzyl when R<2> is H or lower alkyl) or salt thereof. EXAMPLE:5,6-Dihydro-5-methyl-6-oxo-2-piperazino (7H) pyrrolo[2,3-d]pyrimidine expressed by formula II. USE:A remedy for neuropathy. PREPARATION:2-(4-Benzylpiperazino)-5,6-dihydro-5-methyl-6-oxo(7H)pyrro lo[2,3- d]pyrimidine is hydrogenated.
JP20274888A 1987-08-06 1988-08-16 Pyrrolo [2,3-d pyrimidine derivative Expired - Lifetime JPH085887B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP20274888A JPH085887B2 (en) 1987-08-06 1988-08-16 Pyrrolo [2,3-d pyrimidine derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19526787 1987-08-06
JP20274888A JPH085887B2 (en) 1987-08-06 1988-08-16 Pyrrolo [2,3-d pyrimidine derivative

Publications (2)

Publication Number Publication Date
JPS6479183A true JPS6479183A (en) 1989-03-24
JPH085887B2 JPH085887B2 (en) 1996-01-24

Family

ID=26509018

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20274888A Expired - Lifetime JPH085887B2 (en) 1987-08-06 1988-08-16 Pyrrolo [2,3-d pyrimidine derivative

Country Status (1)

Country Link
JP (1) JPH085887B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515232A (en) * 2002-01-14 2005-05-26 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ Use of modified pyrimidine compounds to promote stem cell migration and proliferation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515232A (en) * 2002-01-14 2005-05-26 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US7618621B2 (en) 2002-01-14 2009-11-17 The Board Of Trustees Of The University Of Illinois Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof
US7635467B2 (en) 2002-01-14 2009-12-22 The Board Of Trustees Of The University Of Illinois Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof
US7687505B2 (en) 2002-01-14 2010-03-30 Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US8192732B2 (en) 2002-01-14 2012-06-05 University Of Central Florida Research Foundation, Inc. Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof
US8273756B2 (en) 2002-01-14 2012-09-25 University Of Central Florida Research Foundation, Inc. Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US9084789B2 (en) 2002-01-14 2015-07-21 Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US9358234B2 (en) 2002-01-14 2016-06-07 The Board Of Trustees Of The University Of Illinois Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof

Also Published As

Publication number Publication date
JPH085887B2 (en) 1996-01-24

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