JPS6483065A - Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent - Google Patents

Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent

Info

Publication number
JPS6483065A
JPS6483065A JP24186887A JP24186887A JPS6483065A JP S6483065 A JPS6483065 A JP S6483065A JP 24186887 A JP24186887 A JP 24186887A JP 24186887 A JP24186887 A JP 24186887A JP S6483065 A JPS6483065 A JP S6483065A
Authority
JP
Japan
Prior art keywords
formula
endo
antiarhythmic
cyclopropylene
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP24186887A
Other languages
Japanese (ja)
Inventor
Daisuke Irie
Hiroshi Sumiyama
Ichiro Matsuo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resonac Corp
Original Assignee
Hitachi Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Chemical Co Ltd filed Critical Hitachi Chemical Co Ltd
Priority to JP24186887A priority Critical patent/JPS6483065A/en
Publication of JPS6483065A publication Critical patent/JPS6483065A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I [X is 2-5C alkylene or group of formula II; Y is dialkylamino or group of formula III-formula V; Z is H (the dotted line is C-C bond) or halogen (the dotted line is not C-C bond)] and its acid addition salt. EXAMPLE:N-beta-dimethylaminoethyl endo-cis-3,6-endo cyclopropylene-DELTA<4>-tetrahydro- 1,2-phthalic acid amide. USE:A drug having antiarhythmic action, bronchodilating action, anticholine action and muscle relaxing action. PREPARATION:A compound of formula I wherein Z is H can be produced e.g. by reacting 3,6-endocyclopropylene-DELTA<4>-tetrahydrophthalic anhydride with an amine of formula H2N-X-Y.
JP24186887A 1987-09-25 1987-09-25 Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent Pending JPS6483065A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP24186887A JPS6483065A (en) 1987-09-25 1987-09-25 Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24186887A JPS6483065A (en) 1987-09-25 1987-09-25 Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent

Publications (1)

Publication Number Publication Date
JPS6483065A true JPS6483065A (en) 1989-03-28

Family

ID=17080720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP24186887A Pending JPS6483065A (en) 1987-09-25 1987-09-25 Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent

Country Status (1)

Country Link
JP (1) JPS6483065A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004723A1 (en) * 1993-08-04 1995-02-16 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylalkylamine derivative and pharmaceutical composition thereof
JP2007521273A (en) * 2003-06-20 2007-08-02 シガ テクノロジーズ,インコーポレーテッド Compounds, compositions and methods for treating and preventing orthopoxvirus infection and related diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004723A1 (en) * 1993-08-04 1995-02-16 Yamanouchi Pharmaceutical Co., Ltd. Imidazolylalkylamine derivative and pharmaceutical composition thereof
JP2007521273A (en) * 2003-06-20 2007-08-02 シガ テクノロジーズ,インコーポレーテッド Compounds, compositions and methods for treating and preventing orthopoxvirus infection and related diseases

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