JPS6492A - Novel glycerin derivative, production thereof, hypotensor containing said derivative - Google Patents

Novel glycerin derivative, production thereof, hypotensor containing said derivative

Info

Publication number: JPS6492A
Authority: JP; Japan
Prior art keywords: derivative; formula; production; alkyl; hypotensor
Prior art date: 1986-07-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP62176654A

Other languages

English (en)

Other versions

JP2512311B2 (ja

JPH0192A (ja

Inventor

Mitsuo Mazaki

Hiromitsu Takeda

Toshiro Kamishiro

Masao Yamamoto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Nippon Chemiphar Co Ltd

Original Assignee

Nippon Chemiphar Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-14

Filing date

1987-07-14

Publication date

1989-01-05

1987-07-14 Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd

1989-01-05 Publication of JPH0192A publication Critical patent/JPH0192A/ja

1989-01-05 Publication of JPS6492A publication Critical patent/JPS6492A/ja

1996-07-03 Application granted granted Critical

1996-07-03 Publication of JP2512311B2 publication Critical patent/JP2512311B2/ja

2011-07-03 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

150000002314 glycerols Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
-1 2-Acetyloxy-3-hexadecyloxypropyl 1, 1-dimethylpiperidinio-3-yl Chemical group 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
150000008065 acid anhydrides Chemical class 0.000 abstract 1
150000001263 acyl chlorides Chemical class 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
235000021317 phosphate Nutrition 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP62176654A 1986-07-14 1987-07-14 新規なグリセリン誘導体及び血圧降下剤 Expired - Lifetime JP2512311B2 (ja)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP61-165330		1986-07-14
JP16533086		1986-07-14
JP6219487		1987-03-17
JP62-62194		1987-03-17

Publications (3)

Publication Number	Publication Date
JPH0192A JPH0192A (ja)	1989-01-05
JPS6492A true JPS6492A (en)	1989-01-05
JP2512311B2 JP2512311B2 (ja)	1996-07-03

Family

ID=26403252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP62176654A Expired - Lifetime JP2512311B2 (ja)	1986-07-14	1987-07-14	新規なグリセリン誘導体及び血圧降下剤

Country Status (5)

Country	Link
US (1)	US5053402A (ja)
EP (1)	EP0257762B1 (ja)
JP (1)	JP2512311B2 (ja)
DE (1)	DE3765502D1 (ja)
ES (1)	ES2036210T3 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2010037308A (ja) *	2008-08-08	2010-02-18	Miyoshi Oil & Fat Co Ltd	リン酸化物
JP2012056897A (ja) *	2010-09-09	2012-03-22	Otsuka Chem Co Ltd	環状第４級アンモニウム塩、それを用いた電解質組成物、及び該電解質組成物を用いた電気化学デバイス

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0284395B1 (en) *	1987-03-24	1993-06-23	Nippon Chemiphar Co., Ltd.	Novel glycerol derivative and anti-hypertensive agent
US6172050B1 (en)	1992-07-11	2001-01-09	Asta Medica Aktiengesellschaft	Phospholipid derivatives
DE4222910A1 (de) *	1992-07-11	1994-01-13	Asta Medica Ag	Neue Phospholipidderivate
US9771385B2 (en)	2014-11-26	2017-09-26	Vascular Biogenics Ltd.	Oxidized lipids
EP3223824B1 (en)	2014-11-26	2021-01-06	Vascular Biogenics Ltd.	Oxidized lipids and treatment or prevention of fibrosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4493832A (en) *	1981-07-03	1985-01-15	Fujisawa Pharmaceutical Co., Ltd.	Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
US4710579A (en) *	1984-11-09	1987-12-01	Takeda Chemical Industries, Ltd.	2-(acetoacetyloxy)-3-(octadecyloxy)propyl-3-trimethylammoniopropyl phosphate or a pharmaceutically acceptable salt thereof

1987
- 1987-07-14 ES ES198787306211T patent/ES2036210T3/es not_active Expired - Lifetime
- 1987-07-14 DE DE8787306211T patent/DE3765502D1/de not_active Expired - Fee Related
- 1987-07-14 EP EP87306211A patent/EP0257762B1/en not_active Expired - Lifetime
- 1987-07-14 JP JP62176654A patent/JP2512311B2/ja not_active Expired - Lifetime
1989
- 1989-11-22 US US07/438,996 patent/US5053402A/en not_active Expired - Fee Related

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2010037308A (ja) *	2008-08-08	2010-02-18	Miyoshi Oil & Fat Co Ltd	リン酸化物
JP2012056897A (ja) *	2010-09-09	2012-03-22	Otsuka Chem Co Ltd	環状第４級アンモニウム塩、それを用いた電解質組成物、及び該電解質組成物を用いた電気化学デバイス

Also Published As

Publication number	Publication date
JP2512311B2 (ja)	1996-07-03
US5053402A (en)	1991-10-01
EP0257762B1 (en)	1990-10-10
ES2036210T3 (es)	1993-05-16
EP0257762A2 (en)	1988-03-02
DE3765502D1 (de)	1990-11-15
EP0257762A3 (en)	1988-05-11

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