KR20010040932A - 인터루킨-12 및 호흡기 합포체 바이러스 항원을 포함하는백신 - Google Patents

인터루킨-12 및 호흡기 합포체 바이러스 항원을 포함하는백신 Download PDF

Info

Publication number
KR20010040932A
KR20010040932A KR1020007008845A KR20007008845A KR20010040932A KR 20010040932 A KR20010040932 A KR 20010040932A KR 1020007008845 A KR1020007008845 A KR 1020007008845A KR 20007008845 A KR20007008845 A KR 20007008845A KR 20010040932 A KR20010040932 A KR 20010040932A
Authority
KR
South Korea
Prior art keywords
aloh
rsv
protein
interleukin
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020007008845A
Other languages
English (en)
Korean (ko)
Inventor
핸콕제랄드이.
엘드릿지존에이치.
Original Assignee
윌리암 에이취 캘넌, 에곤 이 버그
아메리칸사이아나미드컴파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 윌리암 에이취 캘넌, 에곤 이 버그, 아메리칸사이아나미드컴파니 filed Critical 윌리암 에이취 캘넌, 에곤 이 버그
Publication of KR20010040932A publication Critical patent/KR20010040932A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • A61K2039/55527Interleukins
    • A61K2039/55538IL-12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020007008845A 1998-02-12 1999-02-10 인터루킨-12 및 호흡기 합포체 바이러스 항원을 포함하는백신 Withdrawn KR20010040932A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7445098P 1998-02-12 1998-02-12
US60/074,450 1998-02-12
PCT/US1999/002848 WO1999040937A2 (fr) 1998-02-12 1999-02-10 Vaccins renfermant l'interleukine-12 et antigenes du virus respiratoire syncytial

Publications (1)

Publication Number Publication Date
KR20010040932A true KR20010040932A (ko) 2001-05-15

Family

ID=22119624

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007008845A Withdrawn KR20010040932A (ko) 1998-02-12 1999-02-10 인터루킨-12 및 호흡기 합포체 바이러스 항원을 포함하는백신

Country Status (9)

Country Link
EP (1) EP1053016A2 (fr)
JP (1) JP2002502883A (fr)
KR (1) KR20010040932A (fr)
CN (1) CN1295480A (fr)
AU (1) AU2596699A (fr)
BR (1) BR9907885A (fr)
CA (1) CA2320042A1 (fr)
IL (1) IL137810A0 (fr)
WO (1) WO1999040937A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515322A (en) 1999-05-13 2004-03-26 Wyeth Corp Adjuvant combination formulations
AU2001270031B2 (en) * 2000-06-22 2005-11-03 Wyeth Holdings Corporation QS-21 and IL-12 as an adjuvant combination
US20030129161A1 (en) * 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
CN108300705B (zh) * 2017-01-12 2021-10-22 厦门大学 稳定呼吸道合胞病毒融合蛋白的方法
CN110684747B (zh) 2018-07-06 2024-05-24 厦门大学 灭活及保存呼吸道合胞病毒的方法
CN118141910B (zh) * 2024-04-03 2025-10-28 河北医科大学 甲基转移酶抑制剂作为呼吸道合胞病毒疫苗及过敏疫苗佐剂的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571515A (en) * 1994-04-18 1996-11-05 The Wistar Institute Of Anatomy & Biology Compositions and methods for use of IL-12 as an adjuvant
DK0784486T3 (da) * 1994-10-05 2006-08-14 Univ Vanderbilt Interleukin-12 som en adjuvans til Paramyxoviridae-vacciner
GB9422990D0 (en) * 1994-11-15 1995-01-04 Cortecs Ltd Immunogenic compositions

Also Published As

Publication number Publication date
CN1295480A (zh) 2001-05-16
WO1999040937A2 (fr) 1999-08-19
WO1999040937A3 (fr) 1999-10-28
BR9907885A (pt) 2000-11-14
AU2596699A (en) 1999-08-30
JP2002502883A (ja) 2002-01-29
IL137810A0 (en) 2001-10-31
EP1053016A2 (fr) 2000-11-22
CA2320042A1 (fr) 1999-08-19

Similar Documents

Publication Publication Date Title
AU648509B2 (en) Stable vaccine compositions containing interleukins
CN1292706A (zh) 用白细胞介素-12配制的肺炎球菌和脑膜炎球菌疫苗
EP0482068A1 (fr) Cytokine et supports d'hormone pour vaccins conjugues
CA2409406C (fr) Qs-21 et il-12 utilises comme combinaison d'adjuvants
KR100622716B1 (ko) 인터루킨-12 및 허피스 심플렉스 바이러스 항원을포함하는 백신
AU2001270031A1 (en) QS-21 and IL-12 as an adjuvant combination
CA2215968A1 (fr) Methode d'amelioration de la reponse d'anticorps a des antigenes specifiques avec l'interleukine-10
AU758111B2 (en) Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects
EP1178825B1 (fr) Preparations de combinaisons d'adjuvants
KR20010040932A (ko) 인터루킨-12 및 호흡기 합포체 바이러스 항원을 포함하는백신
EP0913157B1 (fr) Vaccin composite contenant un antigene, un anticorps et un adn recombinant et son procede de preparation
KR20070048140A (ko) 온코세르카 볼불러스의 천연 생성물의 항원보강성 및 면역강화 특성
KR100863368B1 (ko) 조합 보조 제제
MXPA00007881A (en) Vaccines comprising interleukin-12 and respiratory syncytial viral antigens
MXPA00007878A (fr)

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20000811

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid