KR20090077666A - Liquid composition for caries prevention - Google Patents
Liquid composition for caries prevention Download PDFInfo
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- KR20090077666A KR20090077666A KR1020080127590A KR20080127590A KR20090077666A KR 20090077666 A KR20090077666 A KR 20090077666A KR 1020080127590 A KR1020080127590 A KR 1020080127590A KR 20080127590 A KR20080127590 A KR 20080127590A KR 20090077666 A KR20090077666 A KR 20090077666A
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- tooth decay
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- 208000002925 dental caries Diseases 0.000 title claims abstract description 30
- 239000000203 mixture Substances 0.000 title claims abstract description 14
- 239000007788 liquid Substances 0.000 title claims abstract description 10
- 230000002265 prevention Effects 0.000 title claims 3
- 150000003839 salts Chemical class 0.000 claims abstract description 14
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000011737 fluorine Substances 0.000 claims abstract description 9
- 229910052731 fluorine Inorganic materials 0.000 claims abstract description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 7
- 239000011775 sodium fluoride Substances 0.000 claims abstract description 6
- 235000013024 sodium fluoride Nutrition 0.000 claims abstract description 6
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims abstract 3
- 239000011780 sodium chloride Substances 0.000 claims description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 3
- 239000011575 calcium Substances 0.000 claims description 3
- 229910052791 calcium Inorganic materials 0.000 claims description 3
- 235000019643 salty taste Nutrition 0.000 abstract description 3
- 108010011485 Aspartame Proteins 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract description 2
- 239000000605 aspartame Substances 0.000 abstract description 2
- 235000010357 aspartame Nutrition 0.000 abstract description 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 abstract description 2
- 229960003438 aspartame Drugs 0.000 abstract description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract description 2
- 235000019204 saccharin Nutrition 0.000 abstract description 2
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 abstract description 2
- 229940081974 saccharin Drugs 0.000 abstract description 2
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 abstract description 2
- 239000000811 xylitol Substances 0.000 abstract description 2
- 235000010447 xylitol Nutrition 0.000 abstract description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract description 2
- 229960002675 xylitol Drugs 0.000 abstract description 2
- 239000001736 Calcium glycerylphosphate Substances 0.000 abstract 1
- MEYPRMGRFQCXHY-UHFFFAOYSA-N [Na].F[Si](F)(F)F Chemical compound [Na].F[Si](F)(F)F MEYPRMGRFQCXHY-UHFFFAOYSA-N 0.000 abstract 1
- UHHRFSOMMCWGSO-UHFFFAOYSA-L calcium glycerophosphate Chemical compound [Ca+2].OCC(CO)OP([O-])([O-])=O UHHRFSOMMCWGSO-UHFFFAOYSA-L 0.000 abstract 1
- 229940095618 calcium glycerophosphate Drugs 0.000 abstract 1
- 235000019299 calcium glycerylphosphate Nutrition 0.000 abstract 1
- 230000000873 masking effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 description 9
- 210000000214 mouth Anatomy 0.000 description 9
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 6
- 235000000346 sugar Nutrition 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 239000002324 mouth wash Substances 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 208000003265 stomatitis Diseases 0.000 description 3
- 206010006326 Breath odour Diseases 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 210000003298 dental enamel Anatomy 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 239000004278 EU approved seasoning Substances 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 208000032974 Gagging Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 206010038776 Retching Diseases 0.000 description 1
- 230000000922 anti-bactericidal effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 229940091249 fluoride supplement Drugs 0.000 description 1
- 238000003682 fluorination reaction Methods 0.000 description 1
- 150000002222 fluorine compounds Chemical class 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- YUOWTJMRMWQJDA-UHFFFAOYSA-J tin(iv) fluoride Chemical compound [F-].[F-].[F-].[F-].[Sn+4] YUOWTJMRMWQJDA-UHFFFAOYSA-J 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
Description
본 발명은 충치를 예방하기 위한 구강용 세정액에 관한 것으로서, 더욱 상세하게는 알칼리수를 용매로 하고 여기에 소금과 불소를 첨가하여 충치를 예방하는 것을 특징으로 하는 충치예방용 액체 조성물에 관한 것이다. The present invention relates to a mouthwash for preventing tooth decay, and more particularly to a liquid composition for preventing tooth decay, characterized in that alkaline water is used as a solvent and salt and fluorine are added thereto to prevent tooth decay.
충치를 예방하기 위하여 가장 많이 사용하는 방법은 치약을 이용한 칫솔질이다. 그러나 칫솔질로는 치아에 묻은 음식물찌꺼기는 닦아낼 수 있지만, 혀와 입천장에 묻은 것은 다 닦아낼 수가 없다. 또한 간식이나 음료를 먹고 마시면 여기에 포함된 당분이 구강 내에 남아 있지만, 그때마다 양치질을 할 수도 없고, 자주 양치질을 하게 되면 치아가 빨리 마모될 우려가 있다. 치약 외에 구강세정제가 나와 있지만, 그것은 대부분 살균 및 항균제를 사용하여 치과 치료 후에 염증을 예방하기 위한 것이 주목적이며, 또한 제약회사에서는 장기적으로 사용하면 부작용이 발생하므로 한 달 이상 사용하지 말 것을 권장하고 있다. 기타 생약추출물로 만든 구강세정제가 있지만, 충치의 근본 원인이 되는 당분과 산성분을 희석하는 것이 아니라, 충치균에 대한 항균 및 살균을 위한 것이므로 충치를 근본적으로 예방하기에 부족하다.The most common way to prevent tooth decay is to brush your teeth with toothpaste. However, while brushing can wipe off food debris on your teeth, you can't wipe everything off your tongue and palate. In addition, if you eat snacks and drinks, the sugar contained in it remains in the oral cavity, but you can not brush your teeth every time, and if you brush your teeth frequently, there is a fear that teeth wear out quickly. In addition to toothpaste, mouthwashes are available, but most of them use antiseptic and antimicrobial agents to prevent inflammation after dental treatment, and drug companies recommend not to use it for more than a month because long-term use may cause side effects. . There are mouthwashes made from other herbal extracts, but they do not dilute sugar and acid components, which are the root cause of tooth decay, but are antibacterial and sterilized against caries, which is insufficient to prevent tooth decay.
따라서 본 발명에서는 충치균에 대한 항균이나 살균이 목적이 아니라, 알칼리수와 소금과 불소를 이용하여 충치균의 서식환경을 어렵게 만들고, 나아가 치아를 튼튼하게 하여 충치를 예방하는 것을 특징으로 하는 충치예방용 액체 조성물을 제공하는 것을 목적으로 한다.Therefore, the present invention is not intended for the antibacterial or sterilization of caries, but using alkaline water, salt and fluorine to make the habitat environment of the caries difficult, further strengthen the teeth to prevent tooth decay, characterized in that to prevent tooth decay. The purpose is to provide.
위와 같은 목적을 달성하기 위하여 산성분을 희석하는 ph10정도의 알칼리수를 용매로 하여, 여기에 당분을 희석하는 소금을 첨가해 0.9 ~ 2.5 중량%의 염도를 가진 알칼리성 식염수로 만들고, 치아를 튼튼하게 하여 충치를 예방하는 불소 0.02~ 1.5 중량%을 첨가한다. 짠맛을 마스킹하고 청량감을 주기 위하여 소비자의 취향과 제조자의 필요에 따라 향미료와 청량제 등을 첨가할 수 있다.In order to achieve the above object, the solvent is made of alkaline water having a pH of about 10 diluting the acid component, and salt is added to dilute sugar to make alkaline saline with a salinity of 0.9 to 2.5% by weight. Add 0.02 to 1.5% by weight of fluoride to prevent tooth decay. In order to mask salty taste and give a refreshing feeling, flavors and refreshing agents may be added according to the taste of the consumer and the needs of the manufacturer.
상기 과제해결수단에 따른 본 발명의 충치예방용 액체 조성물로 가글을 하면 구강 내의 산도가 낮아지고 알칼리성으로 변화되기 때문에 충치균이 활동하기 어려워지고, 염분이 충치균의 양분인 당분을 희석하여 충치균의 서식하기 어려운 환경이 된다. 또한 식초와 같은 산성분을 중화해 치아를 보호하며, 나아가 치아를 튼튼하게 하여 충치를 예방하는 효과가 있다.When the gargle with the liquid composition for preventing caries of the present invention according to the above-mentioned solutions to the problem, the acidity in the oral cavity is lowered and changes to alkaline, so it becomes difficult for the cavities to become active, and the salt is diluted with the nutrients of the cavities to incubate the cavities. It is a difficult environment. In addition, by neutralizing acid components such as vinegar to protect the teeth, it is also effective to prevent tooth decay by strengthening the teeth.
더 나아가 구강 내의 음식물찌꺼기를 제거하여 구취와 구내염도 예방할 수 있다.Furthermore, you can prevent bad breath and stomatitis by removing food debris from your mouth.
본 발명에 따른 충치예방용 액체 조성물을 조성하기 위한 구체적인 설명은 다음과 같다.Detailed description for the composition of the liquid composition for preventing caries according to the present invention is as follows.
본 발명의 구성은 ph7.5 ~ ph 10.5 바람직하게는 ph8.5 ~ ph 10의 알칼리수에 죽염이나 구운 소금을 첨가하여 0.9 ~ 2.5 중량%의 염도를 가진 알칼리성 식염수를 만들고 여기에 불소 0.02 ~ 1.5 중량%을 첨가한 것을 특징으로 하는 충치예방용 액체 조성물을 만든다.The composition of the present invention is added to the alkaline water of ph7.5 ~ ph 10.5 preferably ph8.5 ~ ph 10 to make alkaline saline having a salinity of 0.9 to 2.5 wt% by adding bamboo salt or roasted salt and 0.02 to 1.5 wt% fluorine A liquid composition for preventing tooth decay is added.
본 발명은 구강 내의 산도를 낮추어 치아를 산성분으로부터 보호하는 것을 주목적으로 하므로 알칼리수를 용매로 사용한다. 충치가 발생하는 원인은 충치균이 치아에 묻은 당분류를 먹고 배설하는 산에 의해서 법랑질이 상하고, 또한 식초와 같은 조미료로 인하여 치아가 탈석회화되기 때문이다. 충치균이 ph5.5%에서 가장 왕성하게 활동하는데 알칼리수로 가글을 하면 구강 내의 환경이 중성 내지 염기성으로 변하므로 충치균이 활동하기 어려운 환경이 조성된다.The present invention uses alkaline water as a solvent because the main purpose is to protect the teeth from acid by lowering the acidity in the oral cavity. The cause of tooth decay is because the enamel is damaged by the acid from which caries are eaten and excreted from the carbohydrates, and the teeth are demineralized by seasonings such as vinegar. Tooth decay bacteria are most active at pH 5.5%. Gargle with alkaline water changes the environment in the oral cavity from neutral to basic.
알칼리수에 첨가된 소금으로 0.9 ~ 2.5 중량%의 염도를 가진 알칼리성 식염수가 당분을 희석하여 충치균이 서식하기 어려운 환경이 된다. 그리고 음식물에서 포함된 당분은 끈적이는 성질로 구강 내에 잘 접착이 되지만, 염분으로 가글 하면 당분의 끈적이는 성질이 희석되어 치아와 구강 내의 피부로부터 쉽게 분리배출된다.Salt added to alkaline water is alkaline saline with a salt content of 0.9 to 2.5% by weight to dilute sugars, making it difficult for the caries to live. The sugar contained in the food is adhered to the oral cavity with a sticky property, but when salted with salt, the sticky property of the sugar is diluted so that it is easily separated and discharged from the teeth and the skin in the oral cavity.
또한, 소금의 항염증성과 살균 효과로 구내염을 예방된다.In addition, stomatitis is prevented by the anti-inflammatory and bactericidal effect of salt.
상기 알칼리성 식염수에 불소 0.02~ 1.5 중량%, 바람직하게는 0.05 ~ 1.0 중 량%을 첨가하면 불소가 치아에 도포되어 산성분으로부터 치아를 보호하게 되고, 또한 침(타액)에 존재하는 칼슘과 인산염 등의 무기질을 끌어 모아 치아표면에 부착시켜 손상된 범랑질을 재석회화하게 한다. 여기에 사용되는 불소화합물로는 일불소인산나트륨, 불화나트륨, 불화주석,산성 불화인산염 등이 있지만, 본 발명에서는 수돗물 불소화에 주로 사용되는 불화나트륨과 불화규소나트륨을 1종 선택하여 첨가한다.When 0.02 to 1.5% by weight of fluorine, preferably 0.05 to 1.0% by weight, is added to the alkaline saline solution, fluorine is applied to the teeth to protect the teeth from acid components, and calcium and phosphate in saliva (saliva), etc. It collects the minerals and attaches them to the tooth surface to remineralize the damaged enamel. Examples of the fluorine compound used herein include sodium monofluorophosphate, sodium fluoride, tin fluoride, and acid phosphate. In the present invention, sodium fluoride and sodium fluoride which are mainly used for fluorination of tap water are selected and added.
그리고 재석회화에 효과가 우수한 칼슘글리세로포스페이트 0.05 ~ 2.0 중량%을 첨가할 수도 있다.And it is also possible to add 0.05 to 2.0% by weight of calcium glycophosphate excellent in remineralization effect.
한편 알칼리수를 만드는 방법은 안정성이 입증되어 있는 수산화나트륨액을 증류수에 희석하여 만들거나, 수돗물을 전기분해하여 ph 7.5 ~ ph10.5의 알칼리수를 조성한다. 불소와 소금을 첨가한 후에도 수소이온농도(ph)가 7.5 ~ 10.5의 알칼리수가 되게 조성한다.On the other hand, the method of making alkaline water is made by diluting sodium hydroxide solution, which has been proven to be stable, or electrolyzing tap water to form alkaline water of pH 7.5 to ph10.5. Even after the addition of fluorine and salt, the hydrogen ion concentration (ph) is formed so that the alkaline water of 7.5 ~ 10.5.
그리고 본 발명에서 짠맛을 마스킹하기 위하여 사카린, 아스파탐, 자일리톨 등을 첨가하고,가글을 했을 때 청량감을 주고 구취를 가리기 위하여 페퍼민트오일, 멘톨, 솔잎추출물이나 녹차추출물 등을 단독 또는 혼용하여 첨가하는 것이 바람직하다고 하겠다.In addition, saccharin, aspartame, xylitol, and the like are added in order to mask salty taste in the present invention, and it is preferable to add peppermint oil, menthol, pine needle extract or green tea extract, etc. alone or in combination, in order to give a refreshing feeling when gagging. I will say.
이렇게 조성된 충치예방용 액체 조성물 10cc정도를 입에 넣고 20초정도 가글을 한 후에 뱉어내면 구강 내의 환경이 알칼리성으로 변화되어 충치균의 활동을 어렵게 만들고, 산성분으로부터 치아가 보호되며, 또한 불소가 치아를 산성분으로부터 보호할 뿐만 아니라 치아의 재석회화를 돕기 때문에 충치를 예방하게 된다.If 10cc of liquid composition for preventing tooth decay is put into the mouth and spited for about 20 seconds, then spit out, the environment in the oral cavity becomes alkaline, making the activity of dental caries difficult, and the tooth protected from acid. Protects against tooth decay because it not only protects against acid, but also helps remineralize teeth.
나아가 구취와 구내염을 예방할 수 있다. Furthermore, bad breath and stomatitis can be prevented.
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| US12318406B2 (en) | 2013-03-15 | 2025-06-03 | Cda Research Group, Inc. | Methods of treatment using topical copper ion formulations |
| US11318089B2 (en) | 2013-03-15 | 2022-05-03 | Cda Research Group, Inc. | Topical copper ion treatments and methods of making topical copper ion treatments for use in various anatomical areas of the body |
| US11007143B2 (en) | 2013-03-15 | 2021-05-18 | Cda Research Group, Inc. | Topical copper ion treatments and methods of treatment using topical copper ion treatments in the oral-respiratory-otic areas of the body |
| US11000545B2 (en) | 2013-03-15 | 2021-05-11 | Cda Research Group, Inc. | Copper ion compositions and methods of treatment for conditions caused by coronavirus and influenza |
| US11083750B2 (en) | 2013-03-15 | 2021-08-10 | Cda Research Group, Inc. | Methods of treatment using topical copper ion formulations |
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