KR20140124767A - 염증성 질환 및 장애의 치료에 관한 방법 - Google Patents
염증성 질환 및 장애의 치료에 관한 방법 Download PDFInfo
- Publication number
- KR20140124767A KR20140124767A KR1020147022156A KR20147022156A KR20140124767A KR 20140124767 A KR20140124767 A KR 20140124767A KR 1020147022156 A KR1020147022156 A KR 1020147022156A KR 20147022156 A KR20147022156 A KR 20147022156A KR 20140124767 A KR20140124767 A KR 20140124767A
- Authority
- KR
- South Korea
- Prior art keywords
- expression
- level
- patient
- gene
- cfd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12154917 | 2012-02-10 | ||
| EP12154917.4 | 2012-02-10 | ||
| US201261597924P | 2012-02-13 | 2012-02-13 | |
| US61/597,924 | 2012-02-13 | ||
| PCT/EP2013/052629 WO2013117751A2 (en) | 2012-02-10 | 2013-02-11 | Methods related to treatment of inflammatory diseases and disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20140124767A true KR20140124767A (ko) | 2014-10-27 |
Family
ID=48948117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147022156A Withdrawn KR20140124767A (ko) | 2012-02-10 | 2013-02-11 | 염증성 질환 및 장애의 치료에 관한 방법 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2812445A2 (de) |
| KR (1) | KR20140124767A (de) |
| CN (1) | CN104204230A (de) |
| AU (1) | AU2013217940A1 (de) |
| BR (1) | BR112014019274A2 (de) |
| CA (1) | CA2864133A1 (de) |
| MX (1) | MX2014009490A (de) |
| WO (1) | WO2013117751A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230003433A (ko) | 2016-05-20 | 2023-01-05 | 세다르스-신나이 메디칼 센터 | 유전자에 기반한 염증성 장 질환의 진단 |
| CN110244053B (zh) * | 2019-05-09 | 2022-03-11 | 北京大学第三医院(北京大学第三临床医学院) | 用于诊断狼疮肾炎并肺动脉高压疾病的分子标志物及其用途 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4713901A (en) | 1999-12-07 | 2001-06-25 | Parthus Technologies Plc | Model for charge pump phase-locked loop |
| ES2387394T3 (es) | 1999-12-23 | 2012-09-21 | Zymogenetics, Inc. | Procedimiento de tratamiento de la inflamación |
| DE10227527A1 (de) | 2002-06-20 | 2004-01-08 | Clariant Gmbh | Verfahren zur Herstellung von Disazopigmenten |
| US7435800B2 (en) | 2003-05-23 | 2008-10-14 | Chi-Mei Medical Center | Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation |
| EP1697418A2 (de) | 2003-11-21 | 2006-09-06 | ZymoGenetics, Inc. | Anti-il-20-rezeptor-antikörper und bindungspartner und verfahren zur anwendung bei entzündungen |
| WO2007006858A2 (en) * | 2005-07-12 | 2007-01-18 | Oy Jurilab Ltd | Method for treatment of cardiovascular and metabolic diseases and detecting the risk of the same |
| IES20050495A2 (en) | 2005-07-20 | 2006-11-01 | Minroc Techn Promotions Ltd | A drill bit assembly for fluid-operated percussion drill tools |
| WO2007038501A2 (en) | 2005-09-27 | 2007-04-05 | The Feinstein Institute For Medical Research | Rheumatoid arthritis markers |
| WO2007081465A2 (en) | 2005-12-09 | 2007-07-19 | Chi-Mei Medical Center | Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation |
| EP1857559A1 (de) | 2006-05-16 | 2007-11-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Verfahren zur Vorhersage der Sensivität gegenüber TNF-alpha-Blockern |
| US20100267575A1 (en) * | 2006-10-17 | 2010-10-21 | Childrens Hospital Medical Center | Gene array technique for predicting response in inflammatory bowel diseases |
| CA2668955A1 (en) | 2006-11-09 | 2008-05-15 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for predicting therapeutic responsiveness to tnf-alpha blocking agents |
| US20100273671A1 (en) * | 2007-03-01 | 2010-10-28 | Universite Catholique De Louvain | Method for the determination and the classification of rheumatic conditions |
| WO2008132176A2 (en) | 2007-04-27 | 2008-11-06 | Universite Catholique De Louvain | Method for evaluating the response of an individual to tnf blocking therapy |
| SG182183A1 (en) | 2007-06-08 | 2012-07-30 | Biogen Idec Inc | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness |
| US20090004189A1 (en) * | 2007-06-18 | 2009-01-01 | Genentech, Inc. | Biological markers predictive of rheumatoid arthritis response to b-cell antagonists |
| KR20110039218A (ko) | 2008-06-30 | 2011-04-15 | 노보 노르디스크 에이/에스 | 항-인간 인터루킨-20 항체 |
| KR20110048536A (ko) | 2008-08-28 | 2011-05-11 | 와이어쓰 엘엘씨 | 자가면역 질병에서 il-22, il-17 및 il-1 패밀리 시토킨의 용도 |
| NZ594514A (en) | 2009-03-05 | 2013-06-28 | Abbott Lab | Interleukin-17 BINDING PROTEINS |
| US20120020954A1 (en) * | 2009-03-30 | 2012-01-26 | Anat Achiron | Methods of predicting clinical course and treating multiple sclerosis |
| JP5996429B2 (ja) | 2009-09-03 | 2016-09-21 | ジェネンテック, インコーポレイテッド | 関節リウマチの治療、診断及びモニターするための方法 |
| US8580528B2 (en) * | 2009-10-16 | 2013-11-12 | Stichting Vu-Vumc | Method for prognosticating the clinical response of a patient to B-lymphocyte inhibiting or depleting therapy |
| WO2011154139A2 (en) * | 2010-06-07 | 2011-12-15 | Roche Diagnostics Gmbh | Gene expression markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
-
2013
- 2013-02-11 EP EP13704081.2A patent/EP2812445A2/de not_active Withdrawn
- 2013-02-11 KR KR1020147022156A patent/KR20140124767A/ko not_active Withdrawn
- 2013-02-11 WO PCT/EP2013/052629 patent/WO2013117751A2/en not_active Ceased
- 2013-02-11 AU AU2013217940A patent/AU2013217940A1/en not_active Withdrawn
- 2013-02-11 CN CN201380019432.0A patent/CN104204230A/zh not_active Withdrawn
- 2013-02-11 BR BR112014019274A patent/BR112014019274A2/pt not_active IP Right Cessation
- 2013-02-11 CA CA2864133A patent/CA2864133A1/en not_active Withdrawn
- 2013-02-11 MX MX2014009490A patent/MX2014009490A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013117751A3 (en) | 2013-10-03 |
| BR112014019274A2 (pt) | 2017-06-27 |
| AU2013217940A1 (en) | 2014-07-31 |
| EP2812445A2 (de) | 2014-12-17 |
| CN104204230A (zh) | 2014-12-10 |
| WO2013117751A2 (en) | 2013-08-15 |
| MX2014009490A (es) | 2014-08-29 |
| CA2864133A1 (en) | 2013-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Raterman et al. | The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients | |
| Yao et al. | Development of potential pharmacodynamic and diagnostic markers for anti-IFN-α monoclonal antibody trials in systemic lupus erythematosus | |
| US20150315643A1 (en) | Blood transcriptional signatures of active pulmonary tuberculosis and sarcoidosis | |
| WO2016207653A1 (en) | Detection of chromosome interactions | |
| JP2013503643A (ja) | 関節リウマチの治療、診断及びモニターするための方法 | |
| US20250257407A1 (en) | Diagnostic and therapeutic methods for the treatment of rheumatoid arthritis (ra) | |
| JP2011511804A (ja) | 疾患マーカーおよびその使用 | |
| CN104011223A (zh) | 使用il-17拮抗剂及psa应答或非应答等位基因治疗银屑病性关节炎(psa)的方法 | |
| WO2017093750A1 (en) | Methods for predicting response to anti-tnf therapy | |
| US11262358B2 (en) | Infiltrating immune cell proportions predict anti-TNF response in colon biopsies | |
| CA2741114A1 (en) | Biomarkers for predicting the development of chronic autoimmune diseases | |
| WO2010060999A1 (en) | Predicting clinical response to treatment with a soluble tnf-antagonist, or tnf, or a tnf receptor agonist | |
| EP4127244A2 (de) | Biomarkertafeln zur stratifizierung der reaktion auf eine immuncheckpoint-blockade bei krebs | |
| WO2015132241A1 (en) | Treatment of inflammatory diseases | |
| JP6347477B2 (ja) | 関節リウマチ患者に対する抗il−6受容体抗体治療の有効性予測方法 | |
| EP2675915B1 (de) | Cd4+-t-zellen-gensignatur für rheumatoide arthritis (ra) | |
| WO2013117751A2 (en) | Methods related to treatment of inflammatory diseases and disorders | |
| JP2013021932A (ja) | 関節リウマチに対する抗il−6受容体抗体療法の有効性の予測方法 | |
| WO2009150216A1 (en) | A method for predicting the response to a treatment with anakinra | |
| EP2297347B1 (de) | Verfahren und kits zur überwachung der wirkung von immunmodulatoren auf die adaptive immunität | |
| WO2013186352A1 (en) | Assay and method for predicting therapeutic efficacy of immunoglobulin therapy in individual patients with relapsing remitting multiple sclerosis (rr-ms) | |
| EP3121290A1 (de) | Prognoseverfahren für autoimmunerkrankungen durch genotypisierung genetischer variationen des vasoaktiven darmpeptids | |
| JP2014514915A (ja) | 関節リウマチとsstr2遺伝子の多型との間の遺伝的関連 | |
| US20240002941A1 (en) | Method for predicting patient response to cd40-targeted therapies | |
| EP3488014A1 (de) | Verfahren zur unterscheidung einer toleranten person |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20140807 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1202 | Submission of document of withdrawal before decision of registration |
Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment) Patent event code: PC12021R01D Patent event date: 20141216 |
|
| WITB | Written withdrawal of application |