KR20170020383A - Mic-1 융합 단백질 및 그것의 사용 - Google Patents

Mic-1 융합 단백질 및 그것의 사용 Download PDF

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Publication number: KR20170020383A
Authority: KR; South Korea
Prior art keywords: seq; ala; mic; glu; asp
Prior art date: 2014-06-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

KR1020167037059A

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English (en)

Korean (ko)

Inventor

알란 크리스티안 셔

샤를로트 헬그스트란

미카엘 파올로 바스트너 산드리니

세바스티안 벡 요르겐센

헤닝 토거슨

크리스티안 사스-오룸

스벤 하스트루프

킴 빌바우어 안데르센

Original Assignee

노보 노르디스크 에이/에스

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-06-24

Filing date

2015-06-17

Publication date

2017-02-22

2015-06-17 Application filed by 노보 노르디스크 에이/에스 filed Critical 노보 노르디스크 에이/에스

2017-02-22 Publication of KR20170020383A publication Critical patent/KR20170020383A/ko

Status Withdrawn legal-status Critical Current

Links

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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

KR1020167037059A 2014-06-24 2015-06-17 Mic-1 융합 단백질 및 그것의 사용 Withdrawn KR20170020383A (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP14173664		2014-06-24
EP14173664.5		2014-06-24
PCT/EP2015/063596 WO2015197446A1 (en)	2014-06-24	2015-06-17	Mic-1 fusion proteins and uses thereof

Publications (1)

Publication Number	Publication Date
KR20170020383A true KR20170020383A (ko)	2017-02-22

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ID=51032955

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Application Number	Title	Priority Date	Filing Date
KR1020167037059A Withdrawn KR20170020383A (ko)	2014-06-24	2015-06-17	Mic-1 융합 단백질 및 그것의 사용

Country Status (15)

Country	Link
US (2)	US9272019B2 (2)
EP (1)	EP3160496B1 (2)
JP (1)	JP6696915B2 (2)
KR (1)	KR20170020383A (2)
CN (1)	CN106459222A (2)
AR (1)	AR100945A1 (2)
AU (1)	AU2015279525A1 (2)
BR (1)	BR112016029848A2 (2)
CA (1)	CA2952293A1 (2)
IL (1)	IL249327A0 (2)
MX (1)	MX2016016063A (2)
RU (1)	RU2017101436A (2)
TW (1)	TW201613958A (2)
WO (1)	WO2015197446A1 (2)
ZA (1)	ZA201608214B (2)

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WO2021194257A1 (ko) *	2020-03-25	2021-09-30	(주) 업테라	세포 투과성 펩티드 이량체, 이의 제조방법 및 이를 이용한 카고 전달 시스템

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GB201700567D0 (en)	2017-01-12	2017-03-01	Genagon Therapeutics Ab	Therapeutic agents
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JP2020517657A (ja)	2017-04-20	2020-06-18	ノヴォノルディスクアー／エス	アルブミン融合タンパク質の精製方法
TWI710377B (zh)	2017-05-23	2020-11-21	丹麥商諾佛儂迪克股份有限公司	Ｍｉｃ－１化合物及其用途
CN111163795A (zh)	2017-09-10	2020-05-15	诺沃挪第克公司	用于治疗肥胖症的mic-1和glp-1
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TWI724392B (zh)	2018-04-06	2021-04-11	美商美國禮來大藥廠	生長分化因子15促效劑化合物及其使用方法
CR20200510A (es)	2018-04-09	2020-11-26	Amgen Inc	Protreínas de fusión del factor de diferenciación de crecimiento 15
EP3833974A2 (en)	2018-08-10	2021-06-16	Novartis AG	Gfral extracellular domains and methods of use
US12268733B2 (en)	2018-08-10	2025-04-08	Alexion Pharmaceuticals, Inc.	Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
EA202191105A1 (ru)	2018-10-22	2021-08-03	Янссен Фармацевтика Нв	Слитые белки, полученные из глюкагоноподобного пептида 1 (glp1) и ростового фактора дифференцировки 15 (gdf15), и их применение
EP4041281B1 (en)	2019-10-04	2025-11-26	Amgen Inc.	Use of gdf15 for treating cardiometabolic syndrome and other conditions
CA3161302A1 (en) *	2019-11-26	2021-06-03	Yuhan Corporation	Long-acting gdf15 fusion protein and pharmaceutical composition comprising same
CA3161266A1 (en) *	2019-12-09	2021-06-17	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof
CA3159979A1 (en) *	2019-12-11	2021-06-17	Yeonchul Kim	Fusion polypeptide comprising gdf15 and polypeptide region capable of o-glycosylation
CN115379850A (zh) *	2019-12-24	2022-11-22	裘美娜治疗公司	再生性多肽及其用途
EP4085077A4 (en) *	2019-12-31	2024-01-17	Beijing QL Biopharmaceutical Co., Ltd.	Fusion proteins of glp-1 and gdf15 and conjugates thereof
AU2021337652B2 (en)	2020-09-04	2025-01-30	Alexion Pharmaceuticals, Inc.	Methods for treating bone mineralization disorders
EP4237438A4 (en)	2020-10-27	2024-11-27	Beijing QL Biopharmaceutical Co., Ltd.	GDF15 FUSION PROTEINS AND THEIR USE
CN112694520B (zh) *	2020-12-02	2023-01-17	图凌(杭州)生物医药有限公司	一种人工多肽hm、其抗体及在病理检测中的应用
BR112023016048A2 (pt)	2021-02-12	2023-11-14	Alexion Pharma Inc	Polipeptídeos de fosfatase alcalina e métodos de uso dos mesmos
WO2022219495A1 (en)	2021-04-12	2022-10-20	Novartis Ag	2-((4-((s)-2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-imidazole derivatives as activators of the glp1 receptor for the treatment of obesity
EP4476212A1 (en)	2022-02-10	2024-12-18	Novartis AG	2-((4-((s)-2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-imidazole derivatives as activators of the glp1 receptor for the treatment of obesity
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2015
- 2015-06-17 RU RU2017101436A patent/RU2017101436A/ru unknown
- 2015-06-17 MX MX2016016063A patent/MX2016016063A/es unknown
- 2015-06-17 EP EP15730140.9A patent/EP3160496B1/en not_active Withdrawn - After Issue
- 2015-06-17 CA CA2952293A patent/CA2952293A1/en not_active Withdrawn
- 2015-06-17 AU AU2015279525A patent/AU2015279525A1/en not_active Withdrawn
- 2015-06-17 TW TW104119532A patent/TW201613958A/zh unknown
- 2015-06-17 KR KR1020167037059A patent/KR20170020383A/ko not_active Withdrawn
- 2015-06-17 JP JP2016574944A patent/JP6696915B2/ja not_active Expired - Fee Related
- 2015-06-17 BR BR112016029848A patent/BR112016029848A2/pt not_active Application Discontinuation
- 2015-06-17 CN CN201580033507.XA patent/CN106459222A/zh not_active Withdrawn
- 2015-06-17 WO PCT/EP2015/063596 patent/WO2015197446A1/en not_active Ceased
- 2015-06-17 US US14/742,159 patent/US9272019B2/en not_active Expired - Fee Related
- 2015-06-23 AR ARP150102007A patent/AR100945A1/es active IP Right Grant
2016
- 2016-01-19 US US15/000,637 patent/US9956264B2/en not_active Expired - Fee Related
- 2016-11-28 ZA ZA2016/08214A patent/ZA201608214B/en unknown
- 2016-12-01 IL IL249327A patent/IL249327A0/en unknown

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR102195740B1 (ko) *	2020-03-25	2020-12-28	서울대학교산학협력단	세포 투과성 펩티드 이량체, 이의 제조방법 및 이를 이용한 카고 전달 시스템
WO2021194257A1 (ko) *	2020-03-25	2021-09-30	(주) 업테라	세포 투과성 펩티드 이량체, 이의 제조방법 및 이를 이용한 카고 전달 시스템

Also Published As

Publication number	Publication date
RU2017101436A (ru)	2018-07-24
TW201613958A (en)	2016-04-16
CA2952293A1 (en)	2015-12-30
JP2017528419A (ja)	2017-09-28
BR112016029848A2 (pt)	2017-10-24
CN106459222A (zh)	2017-02-22
WO2015197446A1 (en)	2015-12-30
MX2016016063A (es)	2017-03-10
RU2017101436A3 (2)	2019-02-13
EP3160496B1 (en)	2021-03-03
EP3160496A1 (en)	2017-05-03
AU2015279525A1 (en)	2016-12-15
JP6696915B2 (ja)	2020-05-20
US9956264B2 (en)	2018-05-01
US20160129083A1 (en)	2016-05-12
US20160015784A1 (en)	2016-01-21
US9272019B2 (en)	2016-03-01
ZA201608214B (en)	2018-11-28
AR100945A1 (es)	2016-11-09
IL249327A0 (en)	2017-02-28

Legal Events

Date	Code	Title	Description
2016-12-30	PA0105	International application	Patent event date: 20161230 Patent event code: PA01051R01D Comment text: International Patent Application
2017-02-22	PG1501	Laying open of application
2019-09-04	PC1202	Submission of document of withdrawal before decision of registration	Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment) Patent event code: PC12021R01D Patent event date: 20190904
2019-09-04	WITB	Written withdrawal of application

Publication	Publication Date	Title
KR20170020383A (ko)	2017-02-22	Mic-1 융합 단백질 및 그것의 사용
US12006344B2 (en)	2024-06-11	MIC-1 compounds and use thereof
KR102085605B1 (ko)	2020-03-06	대사 장애를 치료하기 위한 융합 단백질
US8809499B2 (en)	2014-08-19	Fusion protein of human fibroblast growth factor-21 and exendin-4
JP6182600B2 (ja)	2017-08-16	線維芽細胞増殖因子２１タンパク質
EP2468858B1 (en)	2016-05-11	Fusion protein regulating plasma glucose and lipid, its preparation method and use
KR20130115305A (ko)	2013-10-21	Fgf21-연관 장애의 치료 방법
CA2871656A1 (en)	2013-12-19	Fibroblast growth factor 21 variants
EP3481412A1 (en)	2019-05-15	Fusion proteins with extended serum half life
US20170334971A1 (en)	2017-11-23	Alpha-1-Antitrypsin (A1AT) Fusion Proteins and Uses Thereof
KR20240126875A (ko)	2024-08-21	Glp-1과 gdf15의 융합 단백질 및 이의 용도
RU2776529C2 (ru)	2022-07-21	Соединения mic-1 и их применение
HK1235013A1 (en)	2018-03-02	Composition for treating diabetes mellitus comprising insulin and a glp-1/ glucagon dual agonist

KR20170020383A - Mic-1 융합 단백질 및 그것의 사용 - Google Patents

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