KR860001097A - 4-아미노-2-페닐퀴놀린의 제조방법 - Google Patents
4-아미노-2-페닐퀴놀린의 제조방법 Download PDFInfo
- Publication number
- KR860001097A KR860001097A KR1019850005110A KR850005110A KR860001097A KR 860001097 A KR860001097 A KR 860001097A KR 1019850005110 A KR1019850005110 A KR 1019850005110A KR 850005110 A KR850005110 A KR 850005110A KR 860001097 A KR860001097 A KR 860001097A
- Authority
- KR
- South Korea
- Prior art keywords
- formula
- process according
- phenylquinoline
- piperidinecarboxamide
- quinolinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US631971 | 1984-07-18 | ||
| US06/631,971 US4560692A (en) | 1984-07-18 | 1984-07-18 | 4-Piperidino-2-phenylquinolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR860001097A true KR860001097A (ko) | 1986-02-22 |
Family
ID=24533539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019850005110A Withdrawn KR860001097A (ko) | 1984-07-18 | 1985-07-18 | 4-아미노-2-페닐퀴놀린의 제조방법 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4560692A (2) |
| EP (1) | EP0168812A1 (2) |
| JP (1) | JPS6136283A (2) |
| KR (1) | KR860001097A (2) |
| AU (1) | AU4508085A (2) |
| CS (1) | CS252830B2 (2) |
| DK (1) | DK326085A (2) |
| ES (2) | ES8609302A1 (2) |
| FI (1) | FI852790L (2) |
| GR (1) | GR851761B (2) |
| HU (1) | HU194207B (2) |
| IL (1) | IL75825A0 (2) |
| MC (1) | MC1691A1 (2) |
| NO (1) | NO852854L (2) |
| PH (1) | PH21022A (2) |
| PT (1) | PT80824B (2) |
| ZA (1) | ZA854718B (2) |
| ZW (1) | ZW11785A1 (2) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3800868A1 (de) * | 1988-01-14 | 1989-07-27 | Thomae Gmbh Dr K | Mittel zur behandlung von bradycardien und bradyarrhythmien |
| US5304554A (en) * | 1990-04-27 | 1994-04-19 | Emory University | 4-[(alkyl or dialkyl)amino]quinolines and their method of preparation |
| US6166203A (en) * | 1998-02-26 | 2000-12-26 | Neurogen Corporation | Heterocyclic amino substituted heteroaryl fused pyridines; GABA brain receptor ligands |
| WO1999043681A1 (en) | 1998-02-26 | 1999-09-02 | Neurogen Corporation | 4-(4-piperidylmethylamino) substituted heteroaryl fused pyridines: gaba brain receptor ligands |
| US6297256B1 (en) * | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
| US6440995B1 (en) | 1999-10-01 | 2002-08-27 | Hoffman-La Roche Inc. | Quinolin-4-yl derivatives |
| US6339093B1 (en) * | 1999-10-08 | 2002-01-15 | Hoffmann-La Roche Inc. | Isoquinoline derivatives |
| AU5261001A (en) | 2000-04-27 | 2001-11-12 | Imperial Cancer Research Technology Ltd | Condensed heteroaryl derivatives |
| US7825389B2 (en) | 2007-12-04 | 2010-11-02 | Tel Epion Inc. | Method and apparatus for controlling a gas cluster ion beam formed from a gas mixture |
| CA2902734A1 (en) | 2013-03-18 | 2014-09-25 | Genoscience Pharma | Quinolines derivatives as novel anticancer agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1510009A (fr) * | 1966-12-02 | 1968-01-19 | Dérivés de l'amino-4 quinoléine | |
| PT66682B (pt) * | 1976-06-18 | 1978-11-15 | Ind Biolog Francaise | /(quinolyl-4)-propyl-1/-4 piperidines leur preparation et leur utilisation comme medicaments /(quinolyl-4)-propyl/-4 piperidines leur preparation et leur utilisation comme medicaments |
| FR2485014A1 (fr) * | 1980-06-20 | 1981-12-24 | Pharmindustrie | Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments |
| HU190796B (en) * | 1981-06-12 | 1986-11-28 | Roussel Uclaf,Fr | Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives |
-
1984
- 1984-07-18 US US06/631,971 patent/US4560692A/en not_active Expired - Fee Related
-
1985
- 1985-06-17 MC MC851783A patent/MC1691A1/fr unknown
- 1985-06-21 ZA ZA854718A patent/ZA854718B/xx unknown
- 1985-07-16 PH PH32528A patent/PH21022A/en unknown
- 1985-07-16 GR GR851761A patent/GR851761B/el unknown
- 1985-07-16 EP EP85108885A patent/EP0168812A1/de not_active Withdrawn
- 1985-07-16 FI FI852790A patent/FI852790L/fi not_active Application Discontinuation
- 1985-07-16 ZW ZW117/85A patent/ZW11785A1/xx unknown
- 1985-07-16 CS CS855274A patent/CS252830B2/cs unknown
- 1985-07-16 IL IL75825A patent/IL75825A0/xx unknown
- 1985-07-17 HU HU852742A patent/HU194207B/hu unknown
- 1985-07-17 NO NO852854A patent/NO852854L/no unknown
- 1985-07-17 JP JP15617185A patent/JPS6136283A/ja active Pending
- 1985-07-17 DK DK326085A patent/DK326085A/da not_active Application Discontinuation
- 1985-07-17 PT PT80824A patent/PT80824B/pt unknown
- 1985-07-17 AU AU45080/85A patent/AU4508085A/en not_active Abandoned
- 1985-07-17 ES ES545298A patent/ES8609302A1/es not_active Expired
- 1985-07-18 KR KR1019850005110A patent/KR860001097A/ko not_active Withdrawn
-
1986
- 1986-02-17 ES ES552402A patent/ES8705421A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO852854L (no) | 1986-01-20 |
| FI852790A7 (fi) | 1986-01-19 |
| IL75825A0 (en) | 1985-11-29 |
| AU4508085A (en) | 1986-01-23 |
| PH21022A (en) | 1987-06-30 |
| ZW11785A1 (en) | 1986-02-12 |
| DK326085A (da) | 1986-01-19 |
| MC1691A1 (fr) | 1986-07-18 |
| GR851761B (2) | 1985-11-26 |
| ES552402A0 (es) | 1987-05-01 |
| ZA854718B (en) | 1986-03-26 |
| HU194207B (en) | 1988-01-28 |
| PT80824B (en) | 1987-05-27 |
| US4560692A (en) | 1985-12-24 |
| JPS6136283A (ja) | 1986-02-20 |
| CS252830B2 (en) | 1987-10-15 |
| ES8705421A1 (es) | 1987-05-01 |
| EP0168812A1 (de) | 1986-01-22 |
| CS527485A2 (en) | 1987-03-12 |
| FI852790L (fi) | 1986-01-19 |
| ES8609302A1 (es) | 1986-09-01 |
| HUT38333A (en) | 1986-05-28 |
| ES545298A0 (es) | 1986-09-01 |
| FI852790A0 (fi) | 1985-07-16 |
| PT80824A (en) | 1985-08-01 |
| DK326085D0 (da) | 1985-07-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR860001793A (ko) | 벤즈 이미다졸 유도체의 제조방법 | |
| KR860003206A (ko) | 벤조일 페닐우레아의 제조방법 | |
| KR850004482A (ko) | 인돌-3-카르복사미드 유도체의 제조방법 | |
| KR850004492A (ko) | 옥시캄의 엔올 에테르 유도체의 제조방법 | |
| KR830007686A (ko) | 세팔로 스포린 유도체의 제조방법 | |
| KR860004049A (ko) | 퀴놀론카복실산 유도체의 제조방법 | |
| KR850004754A (ko) | 3-인돌 카르복사미드 화합물류의 제조방법 | |
| KR860001064A (ko) | β-락탐 화합물의 제조방법 | |
| KR880011103A (ko) | 5-아미노-4,6-디할로게노피리딘의 제조방법 | |
| KR850007257A (ko) | 테트라 하이드로 퀴놀린-1-알카보닐 이미다졸 유도체의 제조방법 | |
| KR850002460A (ko) | 카르바메이트 화합물의 제조방법 | |
| KR840001152A (ko) | 신규 복소환(複素環) 화합물의 제법 | |
| KR860004037A (ko) | 페닐하이드라진의 제조방법 | |
| KR860001795A (ko) | 트리아진 유도체의 제조방법 | |
| KR830006302A (ko) | 신규 피리미딘 유도체의 제조방법 | |
| KR840002821A (ko) | N-(2,3-에폭시프로필렌)-n-아르알킬술폰아미드 유도체의 제조방법 | |
| KR850004491A (ko) | 아릴벤조티아졸린 유도체의 제조방법 | |
| KR860002474A (ko) | 치환된 페닐술포닐아졸의 제조방법 | |
| KR860002451A (ko) | 아미드 화합물의 제조방법 | |
| KR850005441A (ko) | 3-알콕시-2-(n-피롤리디노)-n-피리딜-n-푸릴메틸(또는 푸릴티에닐)-프로필아민의 제조방법 | |
| KR840004105A (ko) | N,n- 치환된 아졸 카복스 아미드 유도체의 제조방법 | |
| KR850007247A (ko) | 바이페닐릴설포닐 우레아의 제조방법 | |
| KR850004581A (ko) | α,α-디메틸페닐아세트아닐리드 유도체의 제조방법 | |
| KR840003639A (ko) | 이속사졸로피리미딘 유도체의 제조방법 | |
| KR850004471A (ko) | 유기 화합물의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19850718 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |