KR970703128A - 초미세립자에 의한 치아 과민증의 완화(relief of dentinal hypersensitivity by submicron particles) - Google Patents

초미세립자에 의한 치아 과민증의 완화(relief of dentinal hypersensitivity by submicron particles) Download PDF

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KR970703128A
KR970703128A KR1019960706962A KR19960706962A KR970703128A KR 970703128 A KR970703128 A KR 970703128A KR 1019960706962 A KR1019960706962 A KR 1019960706962A KR 19960706962 A KR19960706962 A KR 19960706962A KR 970703128 A KR970703128 A KR 970703128A
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phosphate
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제임스 엘. 징골드
켄네쓰 제이. 마르코비쯔
쿠오-첸 예흐
아도니스 부엘로
제임스 케이 험스
조셉 시노디스
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불리트 리차드 에스.
블록 드러그 컴퍼니, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/28—Zirconium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5426—Polymers characterized by specific structures/properties characterized by the charge cationic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/919—Dental

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  • General Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Abstract

본 발명은 양이온으로 하전된 콜로이드를 함유하는 비인산염계의 경구용 조성물에 관한 것인데, 이 조성물은 치아의 과민증을 치료하는 데 효과적이다.

Description

초미세립자에 의한 치아 과민증의 완화(RELⅠEF OF DENTⅠNAL HYPERSENSTIVITY BY SUBMICRON PARTICLES)
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (20)

  1. 양이온으로 하전된 콜로이드를 함유하는 치아의 과민증을 치료용 비인산염계 조성물.
  2. 제l항에 있어서, 상기 콜로이드가 주기율표의 ⅠB, ⅡA, ⅡB, ⅢA, ⅢB, ⅣA, ⅣB, ⅤA, ⅤB, ⅥB, ⅦB 및 ⅧB 족의 금속 및 란탄족 원소 중에서 선택된 금속 화합물을 함유하는 조성물.
  3. 제2항에 있어서, 상기 콜로이드가 Y, Ce, A1 및 Zr 화합물 중에서 선택된 금속 화합물을 함유하는 조성물.
  4. 제2항에 있어서, 상기 콜로이드가 금속의 할로겐화물, 산화물, 수산화물, 규산염 또는 아세트산염을 함유하는 조성물.
  5. 제1항에 있어서, 상기 조성물이 수용성 현탁액, 치약, 겔, 함수제, 정제, 구강 접착용 패치 및 껌 중에서 선택된, 상기 양이온으로 하전된 콜로이드에 대한 적절한 담체를 추가적으로 함유하는 조성물.
  6. 제5항에 있어서, 이차 제감제를 추가적으로 함유하는 조성물.
  7. 제1항에 있어서, 상기 양이온으로 하전된 콜로이드의 입자 크기가 약 0.001μm∼0.2μm인 조성물.
  8. 제7항에 있어서, 상기 양이온으로 하전된 콜로이드를 상기 조성물의 약 10중량%까지 함유하는 조성물.
  9. 양이온으로 하전된 콜로이드의 양을 최소한 과민증 치아를 국부적으로 제감시키는데 충분하게 함유한 비인산염계 조성물을 상기 치아의 표면에 적용하는 단계로 이루어진 과민증 치아의 치료 방법.
  10. 제9항에 있어서, 상기 조성물이 수용성 현탄액, 치약, 겔, 함수제, 정제, 구강 접착용 패치 및 껌 중에서 선택된, 상기 양이온으로 하전된 콜로이드에 대한 적절한 담체를 추가적으로 함유하는 방법.
  11. 제9항에 있어서, 이차 제감제를 추가적으로 함유하는 방법.
  12. 제9항에 있어서, 상기 양이온으로 하전된 콜로이드의 입자 크기가 약 0.001μm∼0.2μm인 방법.
  13. 양이온으로 하전된 콜로이드의 유효량을 적절한 비인산염계 담체로 현탁액을 만들어 제감성 조성물을 형성시키는 단계로 이루어진 과민증 치아 치료제의 제조 방법.
  14. 제13항에 있어서, 추가적으로 상기 조성물에 이차 제감제를 배합시키는 단계로 이루어지는 방법.
  15. 제13항에 있어서, 상기 양이온으로 하전된 콜로이드의 입자 크기가 약 0.001μm∼0.2μm인 방법.
  16. 환자의 과민증 치아의 최소한 하나에, 양이온으로 하전된 콜로이드를 함유한 비인산염계 조성물의 유효량을 투여하는 것으로 이루어지는 환자에게 유효한 방법이며, 이 효과가 상기 치아의 적어도 국부적이 되는 제감 방법.
  17. 제16항에 있어서, 상기 양이온으로 하전된 콜로이드의 입자 크기가 약 0.001μm∼0.2μm인 방법.
  18. 마모성 감소제로서의 비인산염계 양이온 하전 콜로이드의 용도.
  19. 비인산염계 양이옴 하전 콜로이드가 알루미나, 지르코니아, 세리아 및 이트리아 중에서 선택된 화합물을 함유하는, 비인산염계 양이온 하전 콜로이드를 함유하는 치약.
  20. 양이온으로 하전된 콜로이드가 알루미나, 지르코니아, 세리아 및 이트리아 중에서 선택된 화합물을 함유하는, 양이온으로 하전된 콜로이드를 함유하는 비인산염계 구강 린스제, 함수제 또는 제감성 밀봉제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960706962A 1994-06-06 1995-06-05 초미세립자에 의한 치아 과민증의 완화(relief of dentinal hypersensitivity by submicron particles) Ceased KR970703128A (ko)

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Application Number Priority Date Filing Date Title
US25417894A 1994-06-06 1994-06-06
US08/254,178 1994-06-06
PCT/US1995/007149 WO1995033441A1 (en) 1994-06-06 1995-06-05 Relief of dentinal hypersensitivity by submicron particles

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KR970703128A true KR970703128A (ko) 1997-07-03

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US (1) US5718885A (ko)
EP (1) EP0760647B1 (ko)
JP (1) JPH10504528A (ko)
KR (1) KR970703128A (ko)
AT (1) ATE210956T1 (ko)
AU (1) AU686831B2 (ko)
BR (1) BR9508360A (ko)
CA (1) CA2192315A1 (ko)
DE (1) DE69524747T2 (ko)
DK (1) DK0760647T3 (ko)
ES (1) ES2170154T3 (ko)
FI (1) FI964844A7 (ko)
NZ (1) NZ288826A (ko)
PT (1) PT760647E (ko)
WO (1) WO1995033441A1 (ko)

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AU686831B2 (en) 1998-02-12
JPH10504528A (ja) 1998-05-06
BR9508360A (pt) 1997-10-28
DK0760647T3 (da) 2002-03-18
ATE210956T1 (de) 2002-01-15
US5718885A (en) 1998-02-17
NZ288826A (en) 1998-09-24
EP0760647B1 (en) 2001-12-19
AU2817695A (en) 1996-01-04
FI964844A0 (fi) 1996-12-04
DE69524747D1 (de) 2002-01-31
FI964844L (fi) 1997-01-28
WO1995033441A1 (en) 1995-12-14
ES2170154T3 (es) 2002-08-01
EP0760647A1 (en) 1997-03-12
FI964844A7 (fi) 1997-01-28
EP0760647A4 (en) 1997-05-21
CA2192315A1 (en) 1995-12-14
DE69524747T2 (de) 2002-08-08
PT760647E (pt) 2002-05-31

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