LT2566505T - Cholesterilo esterio tiekimas į steroidogeninius audinius - Google Patents

Cholesterilo esterio tiekimas į steroidogeninius audinius

Info

Publication number: LT2566505T
Authority: LT; Lithuania
Prior art keywords: supply; cholesteryl ester; steroidogenic tissues; steroidogenic; tissues
Prior art date: 2010-05-06

Application number

LTEP11720265.5T

Other languages

English (en)

Inventor

Bruce. J. AUERBACH

Reynold Homan

Brian Krause

Original Assignee

Alphacore Pharma Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-05-06

Filing date

2011-05-06

Publication date

2020-02-10

2011-05-06 Application filed by Alphacore Pharma Llc filed Critical Alphacore Pharma Llc

2020-02-10 Publication of LT2566505T publication Critical patent/LT2566505T/lt

Links

OWTYWMJVQZQWFH-JQTKPCACSA-N CE(20:1(11Z)) Chemical compound C12CC[C@]3(C)C([C@H](C)CCCC(C)C)CCC3C2CC=C2[C@]1(C)CC[C@H](OC(=O)CCCCCCCCC\C=C/CCCCCCCC)C2 OWTYWMJVQZQWFH-JQTKPCACSA-N 0.000 title 1
230000000365 steroidogenetic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01043—Phosphatidylcholine-sterol O-acyltransferase (2.3.1.43), i.e. lecithin-cholesterol acyltransferase or LCAT

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Zoology (AREA)
Transplantation (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

LTEP11720265.5T 2010-05-06 2011-05-06 Cholesterilo esterio tiekimas į steroidogeninius audinius LT2566505T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33190910P	2010-05-06	2010-05-06
PCT/US2011/035500 WO2011140429A1 (en)	2010-05-06	2011-05-06	Delivery of cholesteryl ester to steroidogenic tissues

Publications (1)

Publication Number	Publication Date
LT2566505T true LT2566505T (lt)	2020-02-10

Family

ID=44121177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP11720265.5T LT2566505T (lt)	2010-05-06	2011-05-06	Cholesterilo esterio tiekimas į steroidogeninius audinius

Country Status (23)

Country	Link
US (2)	US20130045194A1 (lt)
EP (1)	EP2566505B1 (lt)
JP (1)	JP6174995B2 (lt)
CN (1)	CN103025348B (lt)
AU (1)	AU2011247985B2 (lt)
BR (1)	BR112012028462A2 (lt)
CA (1)	CA2797126C (lt)
CY (1)	CY1122827T1 (lt)
DK (1)	DK2566505T3 (lt)
ES (1)	ES2764733T3 (lt)
HR (1)	HRP20200008T1 (lt)
HU (1)	HUE047288T2 (lt)
LT (1)	LT2566505T (lt)
ME (1)	ME03682B (lt)
MX (1)	MX336872B (lt)
NZ (1)	NZ603453A (lt)
PL (1)	PL2566505T3 (lt)
PT (1)	PT2566505T (lt)
RS (1)	RS59867B1 (lt)
RU (1)	RU2012152320A (lt)
SI (1)	SI2566505T1 (lt)
SM (1)	SMT202000011T1 (lt)
WO (1)	WO2011140429A1 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2853259A1 (en) *	2013-09-30	2015-04-01	Université Pierre et Marie Curie (Paris 6)	Reconstituted high density lipoproteins composition and uses thereof
JP2021501793A (ja) *	2017-11-07	2021-01-21	アルファコアファーマリミテッドライアビリティカンパニーＡｌｐｈａｃｏｒｅＰｈａｒｍａＬｌｃ	心疾患、心血管疾患及び関連する病状と症状を治療し保護する方法
EP4259280A4 (en) *	2020-12-11	2025-02-12	The Regents Of The University Of Michigan	Compositions and methods for preventing, attenuating, and treating medical conditions with shdl nanoparticles

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998000110A1 (en) *	1996-07-03	1998-01-08	University Of Pittsburgh	Emulsion formulations for hydrophilic active agents
DE69836626T2 (de) *	1997-04-11	2007-04-05	Takeda Pharmaceutical Co. Ltd.	Proteine mit lecithin-cholesterin acetyltransferase-ähnlicher aktivität, deren herstellung und verwendung
CN1561218A (zh) *	2001-07-27	2005-01-05	努特里奇亚有限公司	用于预防和/或治疗败血症的肠道组合物
IL158554A0 (en) *	2003-10-22	2004-05-12	Enzymotec Ltd	Mimetic lipids as dietary supplements
WO2005097805A1 (en)	2004-03-26	2005-10-20	Eli Lilly And Company	Compounds and methods for treating dyslipidemia
EP2452683A3 (en)	2006-06-26	2012-08-22	Amgen Inc.	Methods for treating atherosclerosis
ES2559353T3 (es) *	2007-07-26	2016-02-11	Amgen, Inc	Enzimas lecitina-colesterol aciltransferasa modificadas
WO2009124055A1 (en) *	2008-03-31	2009-10-08	University Of Chicago	Human apoa-i mutants
US8492108B2 (en) *	2009-06-12	2013-07-23	Bruce J. Auerbach	Methods of treating anemia and red blood cell dysfunction with lecithin cholesterol acyltransferase

2011
- 2011-05-06 LT LTEP11720265.5T patent/LT2566505T/lt unknown
- 2011-05-06 US US13/695,919 patent/US20130045194A1/en not_active Abandoned
- 2011-05-06 WO PCT/US2011/035500 patent/WO2011140429A1/en not_active Ceased
- 2011-05-06 SI SI201131832T patent/SI2566505T1/sl unknown
- 2011-05-06 DK DK11720265.5T patent/DK2566505T3/da active
- 2011-05-06 RS RS20200004A patent/RS59867B1/sr unknown
- 2011-05-06 AU AU2011247985A patent/AU2011247985B2/en not_active Ceased
- 2011-05-06 NZ NZ603453A patent/NZ603453A/en not_active IP Right Cessation
- 2011-05-06 BR BR112012028462A patent/BR112012028462A2/pt not_active IP Right Cessation
- 2011-05-06 CN CN201180022792.7A patent/CN103025348B/zh not_active Expired - Fee Related
- 2011-05-06 JP JP2013509288A patent/JP6174995B2/ja not_active Expired - Fee Related
- 2011-05-06 HR HRP20200008TT patent/HRP20200008T1/hr unknown
- 2011-05-06 CA CA2797126A patent/CA2797126C/en not_active Expired - Fee Related
- 2011-05-06 RU RU2012152320/15A patent/RU2012152320A/ru not_active Application Discontinuation
- 2011-05-06 SM SM20200011T patent/SMT202000011T1/it unknown
- 2011-05-06 MX MX2012012711A patent/MX336872B/es active IP Right Grant
- 2011-05-06 PT PT117202655T patent/PT2566505T/pt unknown
- 2011-05-06 HU HUE11720265A patent/HUE047288T2/hu unknown
- 2011-05-06 ME MEP-2020-1A patent/ME03682B/me unknown
- 2011-05-06 ES ES11720265T patent/ES2764733T3/es active Active
- 2011-05-06 EP EP11720265.5A patent/EP2566505B1/en active Active
- 2011-05-06 PL PL11720265T patent/PL2566505T3/pl unknown
2014
- 2014-09-05 US US14/478,456 patent/US20150190479A1/en not_active Abandoned
2020
- 2020-01-09 CY CY20201100021T patent/CY1122827T1/el unknown

Also Published As

Publication number	Publication date
CN103025348A (zh)	2013-04-03
ME03682B (me)	2021-01-20
JP2013528594A (ja)	2013-07-11
EP2566505A1 (en)	2013-03-13
SI2566505T1 (sl)	2020-03-31
CA2797126C (en)	2020-06-02
EP2566505B1 (en)	2019-10-16
NZ603453A (en)	2014-12-24
WO2011140429A1 (en)	2011-11-10
CN103025348B (zh)	2015-09-02
RU2012152320A (ru)	2014-06-20
CY1122827T1 (el)	2021-05-05
MX2012012711A (es)	2012-11-21
ES2764733T3 (es)	2020-06-04
US20130045194A1 (en)	2013-02-21
US20150190479A1 (en)	2015-07-09
PL2566505T3 (pl)	2020-06-29
DK2566505T3 (da)	2020-01-20
SMT202000011T1 (it)	2020-03-13
AU2011247985B2 (en)	2015-12-03
RS59867B1 (sr)	2020-03-31
BR112012028462A2 (pt)	2016-07-19
HUE047288T2 (hu)	2020-04-28
JP6174995B2 (ja)	2017-08-02
HRP20200008T1 (hr)	2020-03-20
AU2011247985A1 (en)	2012-11-29
PT2566505T (pt)	2020-01-15
CA2797126A1 (en)	2011-11-10
MX336872B (es)	2016-02-04

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LT2596786T (lt)	2020-01-10	Eikozapentaeno rūgšties etilo esterio naudojimas hipertriglicidemijai gydyti
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SI2561218T1 (sl)	2015-02-27	Snemljiva konica rotorske lopate
EP2622818A4 (en)	2016-12-28	EXPANSION OF ATTENTION COMMANDS
EP2633007A4 (en)	2014-12-10	RENEWABLE BIO-ESSENCE PRODUCTION
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SG11201400668SA (en)	2014-04-28	Wnt compositions and therapeutic uses of such compositions
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EP2566439A4 (en)	2013-09-25	SKIN CONDITIONING COMPOSITIONS CONTAINING 12-HYDROXYSTEARIC ACID
PT2550095T (pt)	2017-12-18	Ácidos silícicos de suporte de partículas grosseiras
IL244076A0 (en)	2016-04-21	Phosphonate ester derivatives and methods of their synthesis
PL3400958T3 (pl)	2022-01-03	Kompozycje i metody leczenia celiakii
FR2955473B1 (fr)	2012-03-02	Structure de presentoir
EP2563347A4 (en)	2013-04-10	TRANSDERMAL PROPYNYLAMINOINDANE COMPOSITIONS
IT1403611B1 (it)	2013-10-31	Composizione di poliesteri
EP2563379A4 (en)	2013-11-06	SOX9 INHIBITORS
BR112013014291A2 (pt)	2016-09-20	formulação lipossômica de calcetrapib