LT2566505T - Cholesterilo esterio tiekimas į steroidogeninius audinius - Google Patents

Cholesterilo esterio tiekimas į steroidogeninius audinius

Info

Publication number: LT2566505T
Authority: LT; Lithuania
Prior art keywords: supply; cholesteryl ester; steroidogenic tissues; steroidogenic; tissues
Prior art date: 2010-05-06

Application number

LTEP11720265.5T

Other languages

English (en)

Inventor

Bruce. J. AUERBACH

Reynold Homan

Brian Krause

Original Assignee

Alphacore Pharma Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-05-06

Filing date

2011-05-06

Publication date

2020-02-10

2011-05-06 Application filed by Alphacore Pharma Llc filed Critical Alphacore Pharma Llc

2020-02-10 Publication of LT2566505T publication Critical patent/LT2566505T/lt

Links

OWTYWMJVQZQWFH-JQTKPCACSA-N CE(20:1(11Z)) Chemical compound C12CC[C@]3(C)C([C@H](C)CCCC(C)C)CCC3C2CC=C2[C@]1(C)CC[C@H](OC(=O)CCCCCCCCC\C=C/CCCCCCCC)C2 OWTYWMJVQZQWFH-JQTKPCACSA-N 0.000 title 1
230000000365 steroidogenetic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01043—Phosphatidylcholine-sterol O-acyltransferase (2.3.1.43), i.e. lecithin-cholesterol acyltransferase or LCAT

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Zoology (AREA)
Dermatology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

LTEP11720265.5T 2010-05-06 2011-05-06 Cholesterilo esterio tiekimas į steroidogeninius audinius LT2566505T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33190910P	2010-05-06	2010-05-06
PCT/US2011/035500 WO2011140429A1 (en)	2010-05-06	2011-05-06	Delivery of cholesteryl ester to steroidogenic tissues

Publications (1)

Publication Number	Publication Date
LT2566505T true LT2566505T (lt)	2020-02-10

Family

ID=44121177

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP11720265.5T LT2566505T (lt)	2010-05-06	2011-05-06	Cholesterilo esterio tiekimas į steroidogeninius audinius

Country Status (23)

Country	Link
US (2)	US20130045194A1 (lt)
EP (1)	EP2566505B1 (lt)
JP (1)	JP6174995B2 (lt)
CN (1)	CN103025348B (lt)
AU (1)	AU2011247985B2 (lt)
BR (1)	BR112012028462A2 (lt)
CA (1)	CA2797126C (lt)
CY (1)	CY1122827T1 (lt)
DK (1)	DK2566505T3 (lt)
ES (1)	ES2764733T3 (lt)
HR (1)	HRP20200008T1 (lt)
HU (1)	HUE047288T2 (lt)
LT (1)	LT2566505T (lt)
ME (1)	ME03682B (lt)
MX (1)	MX336872B (lt)
NZ (1)	NZ603453A (lt)
PL (1)	PL2566505T3 (lt)
PT (1)	PT2566505T (lt)
RS (1)	RS59867B1 (lt)
RU (1)	RU2012152320A (lt)
SI (1)	SI2566505T1 (lt)
SM (1)	SMT202000011T1 (lt)
WO (1)	WO2011140429A1 (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2853259A1 (en) *	2013-09-30	2015-04-01	Université Pierre et Marie Curie (Paris 6)	Reconstituted high density lipoproteins composition and uses thereof
WO2019092584A1 (en) *	2017-11-07	2019-05-16	Alphacore Pharma Llc	Methods of treating and protecting against cardiac disease, cardiovascular disease and related conditions and symptoms
WO2022125878A1 (en) *	2020-12-11	2022-06-16	The Regents Of The University Of Michigan	Compositions and methods for preventing, attenuating, and treating medical conditions with shdl nanoparticles
WO2026087915A1 (en) *	2024-10-25	2026-04-30	Newamsterdam Pharma B.V.	Treatment and prevention of sepsis or other dysregulated inflammatory responses using cetp inhibitor obicetrapib

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998000110A1 (en) *	1996-07-03	1998-01-08	University Of Pittsburgh	Emulsion formulations for hydrophilic active agents
EP0973914B1 (en) *	1997-04-11	2006-12-13	Takeda Pharmaceutical Company Limited	Proteins having lecithin-cholesterol acyltransferase-like activity, their production and use
AU2002319961A1 (en) *	2001-07-27	2003-02-17	N.V. Nutricia	Enteral compositions for the prevention and/or treatment of sepsis
IL158554A0 (en) *	2003-10-22	2004-05-12	Enzymotec Ltd	Mimetic lipids as dietary supplements
EA200601785A1 (ru)	2004-03-26	2007-02-27	Эли Лилли Энд Компани	Соединения и способы лечения дислипидемии
ATE540681T1 (de)	2006-06-26	2012-01-15	Amgen Inc	Verfahren zur behandlung von atherosklerose
NZ582794A (en) *	2007-07-26	2012-09-28	Amgen Inc	Modified lecithin-cholesterol acyltransferase enzymes
WO2009124055A1 (en) *	2008-03-31	2009-10-08	University Of Chicago	Human apoa-i mutants
MX2011013065A (es) *	2009-06-12	2012-01-20	Alphacore Pharma Llc	Uso de enzima lecitina-colesterol aciltransferasa (lcat) para tratar anemia y difucion de globulos rojos.

2011
- 2011-05-06 DK DK11720265.5T patent/DK2566505T3/da active
- 2011-05-06 RU RU2012152320/15A patent/RU2012152320A/ru not_active Application Discontinuation
- 2011-05-06 AU AU2011247985A patent/AU2011247985B2/en not_active Ceased
- 2011-05-06 SI SI201131832T patent/SI2566505T1/sl unknown
- 2011-05-06 HR HRP20200008TT patent/HRP20200008T1/hr unknown
- 2011-05-06 US US13/695,919 patent/US20130045194A1/en not_active Abandoned
- 2011-05-06 LT LTEP11720265.5T patent/LT2566505T/lt unknown
- 2011-05-06 SM SM20200011T patent/SMT202000011T1/it unknown
- 2011-05-06 PL PL11720265T patent/PL2566505T3/pl unknown
- 2011-05-06 CA CA2797126A patent/CA2797126C/en not_active Expired - Fee Related
- 2011-05-06 MX MX2012012711A patent/MX336872B/es active IP Right Grant
- 2011-05-06 WO PCT/US2011/035500 patent/WO2011140429A1/en not_active Ceased
- 2011-05-06 JP JP2013509288A patent/JP6174995B2/ja not_active Expired - Fee Related
- 2011-05-06 EP EP11720265.5A patent/EP2566505B1/en active Active
- 2011-05-06 RS RS20200004A patent/RS59867B1/sr unknown
- 2011-05-06 BR BR112012028462A patent/BR112012028462A2/pt not_active IP Right Cessation
- 2011-05-06 CN CN201180022792.7A patent/CN103025348B/zh not_active Expired - Fee Related
- 2011-05-06 ES ES11720265T patent/ES2764733T3/es active Active
- 2011-05-06 ME MEP-2020-1A patent/ME03682B/me unknown
- 2011-05-06 PT PT117202655T patent/PT2566505T/pt unknown
- 2011-05-06 HU HUE11720265A patent/HUE047288T2/hu unknown
- 2011-05-06 NZ NZ603453A patent/NZ603453A/en not_active IP Right Cessation
2014
- 2014-09-05 US US14/478,456 patent/US20150190479A1/en not_active Abandoned
2020
- 2020-01-09 CY CY20201100021T patent/CY1122827T1/el unknown

Also Published As

Publication number	Publication date
AU2011247985B2 (en)	2015-12-03
NZ603453A (en)	2014-12-24
JP6174995B2 (ja)	2017-08-02
CN103025348A (zh)	2013-04-03
US20150190479A1 (en)	2015-07-09
JP2013528594A (ja)	2013-07-11
RS59867B1 (sr)	2020-03-31
HUE047288T2 (hu)	2020-04-28
CY1122827T1 (el)	2021-05-05
AU2011247985A1 (en)	2012-11-29
HRP20200008T1 (hr)	2020-03-20
PT2566505T (pt)	2020-01-15
WO2011140429A1 (en)	2011-11-10
MX336872B (es)	2016-02-04
SMT202000011T1 (it)	2020-03-13
RU2012152320A (ru)	2014-06-20
CN103025348B (zh)	2015-09-02
EP2566505B1 (en)	2019-10-16
EP2566505A1 (en)	2013-03-13
CA2797126C (en)	2020-06-02
BR112012028462A2 (pt)	2016-07-19
ES2764733T3 (es)	2020-06-04
MX2012012711A (es)	2012-11-21
US20130045194A1 (en)	2013-02-21
CA2797126A1 (en)	2011-11-10
DK2566505T3 (da)	2020-01-20
SI2566505T1 (sl)	2020-03-31
PL2566505T3 (pl)	2020-06-29
ME03682B (me)	2021-01-20

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EP2622818A4 (en)	2016-12-28	EXPANSION OF ATTENTION COMMANDS
EP2633007A4 (en)	2014-12-10	RENEWABLE BIO-ESSENCE PRODUCTION
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PT2550095T (pt)	2017-12-18	Ácidos silícicos de suporte de partículas grosseiras
IL244076A0 (en)	2016-04-21	Phosphonate ester derivatives and methods of their synthesis
PL3400958T3 (pl)	2022-01-03	Kompozycje i metody leczenia celiakii
FR2955473B1 (fr)	2012-03-02	Structure de presentoir
EP2563347A4 (en)	2013-04-10	TRANSDERMAL PROPYNYLAMINOINDANE COMPOSITIONS
IT1403611B1 (it)	2013-10-31	Composizione di poliesteri
EP2563379A4 (en)	2013-11-06	SOX9 INHIBITORS
HUE047288T2 (hu)	2020-04-28	Koleszteril-észter szteroidogén szövetekbe juttatása