LT2900675T - Tienopirimidino darinių gamybos būdas - Google Patents

Tienopirimidino darinių gamybos būdas

Info

Publication number: LT2900675T
Authority: LT; Lithuania
Prior art keywords: production method; thienopyrimidine derivative; thienopyrimidine; derivative; production
Prior art date: 2012-09-28

Application number

LTEP13779938.3T

Other languages

English (en)

Inventor

Koichiro Fukuoka

Kazuhiro Miwa

Tsuyoshi Sasaki

Fumiya KOMURA

Original Assignee

Takeda Pharmaceutical Company Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-09-28

Filing date

2013-09-27

Publication date

2019-05-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49448235&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2900675(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-09-27 Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited

2019-05-27 Publication of LT2900675T publication Critical patent/LT2900675T/lt

Links

238000004519 manufacturing process Methods 0.000 title 1
RBNBDIMXFJYDLQ-UHFFFAOYSA-N thieno[3,2-d]pyrimidine Chemical class C1=NC=C2SC=CC2=N1 RBNBDIMXFJYDLQ-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

LTEP13779938.3T 2012-09-28 2013-09-27 Tienopirimidino darinių gamybos būdas LT2900675T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2012217679		2012-09-28
PCT/JP2013/077013 WO2014051164A2 (en)	2012-09-28	2013-09-27	Production method of thienopyrimidine derivative

Publications (1)

Publication Number	Publication Date
LT2900675T true LT2900675T (lt)	2019-05-27

Family

ID=49448235

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LTEP18185835.8T LT3415517T (lt)	2012-09-28	2013-09-27	Kristalinė 1-(4-(1-(2,6-difluorbenzil)-5-dimetilaminometil-3-(6-metoksipiridazin-3-il)-2,4-diokso-1,2,3,4- tetrahidrotieno(2,3-d)pirimidin-6-il)fenil)-3-metoksikarbamido forma
LTEP13779938.3T LT2900675T (lt)	2012-09-28	2013-09-27	Tienopirimidino darinių gamybos būdas

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
LTEP18185835.8T LT3415517T (lt)	2012-09-28	2013-09-27	Kristalinė 1-(4-(1-(2,6-difluorbenzil)-5-dimetilaminometil-3-(6-metoksipiridazin-3-il)-2,4-diokso-1,2,3,4- tetrahidrotieno(2,3-d)pirimidin-6-il)fenil)-3-metoksikarbamido forma

Country Status (21)

Country	Link
US (10)	US9758528B2 (lt)
EP (3)	EP4119564A1 (lt)
JP (1)	JP6250564B2 (lt)
CN (3)	CN113372358B (lt)
AR (1)	AR092707A1 (lt)
CA (1)	CA2881132C (lt)
CY (2)	CY1121641T1 (lt)
DK (2)	DK3415517T3 (lt)
ES (2)	ES2724206T3 (lt)
HR (2)	HRP20220622T1 (lt)
HU (2)	HUE044048T2 (lt)
LT (2)	LT3415517T (lt)
PL (2)	PL3415517T3 (lt)
PT (2)	PT2900675T (lt)
RS (2)	RS58703B1 (lt)
SI (2)	SI2900675T1 (lt)
SM (2)	SMT201900255T1 (lt)
TR (1)	TR201906318T4 (lt)
TW (3)	TWI602819B (lt)
UY (1)	UY35058A (lt)
WO (1)	WO2014051164A2 (lt)

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JP2022551316A (ja)	2019-10-10	2022-12-08	ミオバントサイエンシズゲーエムベーハー	Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形
CN112745304A (zh) *	2019-10-29	2021-05-04	上海度德医药科技有限公司	一种Relugolix的制备方法及中间体化合物
CN111423452B (zh) *	2020-03-26	2023-08-22	江西青峰药业有限公司	瑞卢戈利的中间体及其制备方法和应用
CN113444105A (zh) *	2020-03-27	2021-09-28	南京海润医药有限公司	一种Relugolix的制备方法
CN111333633B (zh) *	2020-04-01	2023-10-20	江西科睿药业有限公司	一种瑞卢戈利的中间体化合物及其制备方法和用途
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CN115594688B (zh) *	2021-06-28	2023-11-17	成都倍特药业股份有限公司	瑞卢戈利中间体的制备方法
US20240287090A1 (en) *	2021-09-15	2024-08-29	Cipla Limited	Solid state forms of relugolix
JP2024540922A (ja) *	2021-10-18	2024-11-06	スミトモファーマスウィッツァーランドゲーエムベーハー	Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素のエタノール溶媒和物の結晶形
CN114230576A (zh) *	2021-12-21	2022-03-25	伊诺药物研究(南京)有限公司	一种瑞卢戈利的制备方法
WO2023119333A1 (en) *	2021-12-25	2023-06-29	Dr. Reddy’S Laboratories Limited	Process for preparation of relugolix and its intermediates
CN114409629B (zh) *	2022-02-22	2023-12-29	浙江科聚生物医药有限公司	一种高纯度Relugolix关键中间体的制备方法及应用
CN114790189B (zh) *	2022-02-24	2023-06-09	海化生命(厦门)科技有限公司	瑞卢戈利中间体的制备方法
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2013
- 2013-09-27 AR ARP130103480A patent/AR092707A1/es unknown
- 2013-09-27 CN CN202110609164.4A patent/CN113372358B/zh active Active
- 2013-09-27 CA CA2881132A patent/CA2881132C/en not_active Expired - Fee Related
- 2013-09-27 CN CN201380051107.2A patent/CN104703992B/zh active Active
- 2013-09-27 RS RS20190473A patent/RS58703B1/sr unknown
- 2013-09-27 HU HUE13779938A patent/HUE044048T2/hu unknown
- 2013-09-27 TW TW102134983A patent/TWI602819B/zh active
- 2013-09-27 SI SI201331414T patent/SI2900675T1/sl unknown
- 2013-09-27 LT LTEP18185835.8T patent/LT3415517T/lt unknown
- 2013-09-27 US US14/432,188 patent/US9758528B2/en active Active
- 2013-09-27 ES ES13779938T patent/ES2724206T3/es active Active
- 2013-09-27 JP JP2014557263A patent/JP6250564B2/ja active Active
- 2013-09-27 EP EP22168256.0A patent/EP4119564A1/en active Pending
- 2013-09-27 TW TW107136006A patent/TWI663171B/zh active
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Also Published As

Publication number	Publication date
US9758528B2 (en)	2017-09-12
PL2900675T3 (pl)	2019-08-30
HUE059077T2 (hu)	2022-11-28
SMT202200255T1 (it)	2022-07-21
UY35058A (es)	2014-04-30
TWI641611B (zh)	2018-11-21
US20250368660A1 (en)	2025-12-04
PT2900675T (pt)	2019-05-28
DK3415517T3 (da)	2022-05-30
ES2724206T3 (es)	2019-09-09
US10464945B2 (en)	2019-11-05
CN113372358B (zh)	2024-05-14
TWI602819B (zh)	2017-10-21
US20150266891A1 (en)	2015-09-24
CY1125151T1 (el)	2024-12-13
LT3415517T (lt)	2022-06-10
US10150778B2 (en)	2018-12-11
EP4119564A1 (en)	2023-01-18
CN113372358A (zh)	2021-09-10
RS63199B1 (sr)	2022-06-30
TW201808962A (zh)	2018-03-16
DK2900675T3 (da)	2019-06-03
EP2900675A2 (en)	2015-08-05
RS58703B1 (sr)	2019-06-28
US20220204525A1 (en)	2022-06-30
JP6250564B2 (ja)	2017-12-20
SI3415517T1 (sl)	2022-06-30
US11053257B2 (en)	2021-07-06
US20220135585A1 (en)	2022-05-05
US10544160B2 (en)	2020-01-28
WO2014051164A3 (en)	2014-05-22
CY1121641T1 (el)	2020-07-31
US20190055261A1 (en)	2019-02-21
US20230212184A1 (en)	2023-07-06
CN104703992A (zh)	2015-06-10
EP2900675B1 (en)	2019-03-06
US12180224B2 (en)	2024-12-31
HUE044048T2 (hu)	2019-09-30
ES2913753T3 (es)	2022-06-06
HRP20220622T1 (hr)	2022-06-24
SI2900675T1 (sl)	2019-06-28
HRP20190729T1 (hr)	2019-06-14
US20250051353A1 (en)	2025-02-13
US11795178B2 (en)	2023-10-24
CN109053766B (zh)	2021-06-22
CA2881132C (en)	2020-11-24
SMT201900255T1 (it)	2019-07-11
TWI663171B (zh)	2019-06-21
CA2881132A1 (en)	2014-04-03
WO2014051164A2 (en)	2014-04-03
EP3415517B1 (en)	2022-04-20
US20170210753A1 (en)	2017-07-27
US20200361953A1 (en)	2020-11-19
US12325714B2 (en)	2025-06-10
US20180319816A1 (en)	2018-11-08
JP2015532262A (ja)	2015-11-09
EP3415517A1 (en)	2018-12-19
PL3415517T3 (pl)	2022-07-04
CN109053766A (zh)	2018-12-21
AR092707A1 (es)	2015-04-29
PT3415517T (pt)	2022-05-13
TW201418262A (zh)	2014-05-16
US11731983B2 (en)	2023-08-22
TW201906847A (zh)	2019-02-16
TR201906318T4 (tr)	2019-05-21
CN104703992B (zh)	2019-03-05

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