LT3056492T - Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos - Google Patents

Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos

Info

Publication number: LT3056492T
Authority: LT; Lithuania
Prior art keywords: delafloxacin; drug; crystalline forms; meglumine salt; meglumine
Prior art date: 2004-10-08

Application number

LTEP15199355.7T

Other languages

English (en)

Inventor

Geoff Zhang

Michael Bradley

David Barnes

Rodger Henry

Original Assignee

Abbvie Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-10-08

Filing date

2005-10-07

Publication date

2022-01-25

2005-10-07 Application filed by Abbvie Inc. filed Critical Abbvie Inc.

2022-01-25 Publication of LT3056492T publication Critical patent/LT3056492T/lt

Links

MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical class CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 title 1
DYDCPNMLZGFQTM-UHFFFAOYSA-N delafloxacin Chemical compound C1=C(F)C(N)=NC(N2C3=C(Cl)C(N4CC(O)C4)=C(F)C=C3C(=O)C(C(O)=O)=C2)=C1F DYDCPNMLZGFQTM-UHFFFAOYSA-N 0.000 title 1
229950006412 delafloxacin Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/18—Polyhydroxylic acyclic alcohols
- C07C31/26—Hexahydroxylic alcohols

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

LTEP15199355.7T 2004-10-08 2005-10-07 Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos LT3056492T (lt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US61733404P	2004-10-08	2004-10-08

Publications (1)

Publication Number	Publication Date
LT3056492T true LT3056492T (lt)	2022-01-25

Family

ID=36129950

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP15199355.7T LT3056492T (lt)	2004-10-08	2005-10-07	Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos

Country Status (13)

Country	Link
US (8)	US7728143B2 (lt)
EP (3)	EP3957632A1 (lt)
CA (1)	CA2582954C (lt)
CY (1)	CY1125048T1 (lt)
DK (1)	DK3056492T3 (lt)
ES (1)	ES2901955T3 (lt)
HU (1)	HUE056718T2 (lt)
LT (1)	LT3056492T (lt)
MX (1)	MX2007004111A (lt)
PL (1)	PL3056492T3 (lt)
PT (1)	PT3056492T (lt)
SI (1)	SI3056492T1 (lt)
WO (1)	WO2006042034A2 (lt)

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US7576216B2 (en)	2004-07-30	2009-08-18	Abbott Laboratories	Preparation of pyridonecarboxylic acid antibacterials
US7728143B2 (en) *	2004-10-08	2010-06-01	Abbott Laboratories	Salt and crystalline forms thereof of a drug
WO2006110815A1 (en) *	2005-04-11	2006-10-19	Abbott Laboratories	Pharmaceutical compositions having improved dissolution profiles for poorly soluble drugs
US8497378B2 (en)	2008-09-24	2013-07-30	Rib-X Pharmaceuticals, Inc.	Process for making quinolone compounds
MX2011005117A (es) *	2008-11-15	2011-10-21	Rib X Pharmaceuticals Inc	Composiciones antimicrobianas.
MX2015011651A (es) *	2013-03-08	2016-08-08	Melinta Therapeutics Inc	Formas cristalinas de d-glucitol,1-desoxi-1-(metilamino)-,1-(6-ami no-3,5-difluoropiridin-2-il)-8-cloro-6-fluoro-1,4-dihidro-7-(3-hi droxiazetidin-1-il)-4-oxo-3-quinolincarboxilato.
CA2904387C (en)	2013-03-15	2021-12-07	Melinta Therapeutics, Inc.	Methods of treating infections in overweight and obese patients using antibiotics
TW201605447A (zh) *	2014-06-20	2016-02-16	美林塔治療學有限公司	處理感染的方法
TWI705814B (zh) *	2014-06-20	2020-10-01	美商梅琳塔有限責任公司	醫藥組成物及其用途
HK1244211A1 (zh)	2014-11-14	2018-08-03	Melinta Therapeutics, Inc.	治疗、预防或降低皮肤感染风险的方法
CN105693695A (zh) *	2014-11-24	2016-06-22	重庆医药工业研究院有限责任公司	一种德拉沙星葡甲胺盐的晶型及其制备方法
CN106256824B (zh) *	2015-06-18	2020-10-27	重庆医药工业研究院有限责任公司	一种高纯度德拉沙星葡甲胺盐的制备方法
CN105017223B (zh) *	2015-07-08	2017-08-01	扬子江药业集团有限公司	德拉沙星葡甲胺晶型i及其制备方法
CN105017224A (zh) *	2015-07-10	2015-11-04	扬子江药业集团有限公司	一种德拉沙星葡甲胺晶型的制备方法
CN106916142A (zh) *	2015-12-25	2017-07-04	江苏奥赛康药业股份有限公司	一种制备高纯度德拉沙星的方法
CN111718330A (zh) *	2019-03-23	2020-09-29	南京海润医药有限公司	一种德拉沙星杂质iii及产品精制方法
CN111718331A (zh) *	2019-03-23	2020-09-29	南京海润医药有限公司	德拉沙星的杂质i和ii及产品精制方法
CN111718329A (zh) *	2019-03-23	2020-09-29	南京海润医药有限公司	一种德拉沙星杂质iv及产品精制方法
WO2022240897A1 (en)	2021-05-10	2022-11-17	Sepelo Therapeutics, Llc	Pharmaceutical composition comprising delafloxacin for administration into the lung
CN116514775B (zh) *	2022-01-20	2024-11-29	安徽普利药业有限公司	一种徳拉沙星葡甲胺盐新晶型及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1207994B (it)	1986-01-03	1989-06-01	Therapicon Srl	Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US5578609A (en) *	1994-03-25	1996-11-26	The Dupont Merck Pharmaceutical Company	2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents
ATE221533T1 (de)	1994-04-12	2002-08-15	Arakis Ltd	Verfahren zur racematspaltung von etodolac unter verwendung von glucamin-derivaten
ES2169811T3 (es)	1995-09-22	2002-07-16	Wakunaga Pharma Co Ltd	Nuevos derivados del acido piridonacarboxilico o sus sales y agente antibacteriano que comprende el mismo como ingrediente activo.
EP0945134A1 (de)	1998-03-27	1999-09-29	Boehringer Ingelheim Pharma KG	Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
JP2005097116A (ja)	1999-11-11	2005-04-14	Wakunaga Pharmaceut Co Ltd	キノリンカルボン酸誘導体アルカリ金属塩及びこれを用いたキノリンカルボン酸誘導体の精製法
GB9929037D0 (en) *	1999-12-08	2000-02-02	Glaxo Wellcome Spa	Heterocyclic derivatives
EE200200426A (et)	2000-01-31	2003-12-15	Pfizer Products Inc.	PDE4 isosüümide inhibiitoritena kasulikud pürimidiinkarboksamiidid
JP4337283B2 (ja)	2001-07-11	2009-09-30	ソニー株式会社	光ピックアップ装置及び記録及び／又は再生装置
JP4290381B2 (ja)	2002-04-11	2009-07-01	学校法人聖マリアンナ医科大学	ピリドンカルボン酸化合物含有エマルション
JP2004168772A (ja)	2002-11-06	2004-06-17	Takeda Chem Ind Ltd	受容体調節剤
US7728143B2 (en) *	2004-10-08	2010-06-01	Abbott Laboratories	Salt and crystalline forms thereof of a drug

2005
- 2005-10-07 US US11/245,561 patent/US7728143B2/en active Active
- 2005-10-07 PT PT151993557T patent/PT3056492T/pt unknown
- 2005-10-07 HU HUE15199355A patent/HUE056718T2/hu unknown
- 2005-10-07 PL PL15199355T patent/PL3056492T3/pl unknown
- 2005-10-07 WO PCT/US2005/036024 patent/WO2006042034A2/en not_active Ceased
- 2005-10-07 EP EP21196428.3A patent/EP3957632A1/en not_active Withdrawn
- 2005-10-07 DK DK15199355.7T patent/DK3056492T3/da active
- 2005-10-07 EP EP05825344A patent/EP1802607A2/en not_active Withdrawn
- 2005-10-07 ES ES15199355T patent/ES2901955T3/es not_active Expired - Lifetime
- 2005-10-07 MX MX2007004111A patent/MX2007004111A/es active IP Right Grant
- 2005-10-07 EP EP15199355.7A patent/EP3056492B1/en not_active Expired - Lifetime
- 2005-10-07 LT LTEP15199355.7T patent/LT3056492T/lt unknown
- 2005-10-07 SI SI200532302T patent/SI3056492T1/sl unknown
- 2005-10-09 CA CA2582954A patent/CA2582954C/en not_active Expired - Lifetime
2010
- 2010-02-05 US US12/701,254 patent/US8252813B2/en active Active
- 2010-04-20 US US12/763,476 patent/US8273892B2/en active Active
2012
- 2012-08-27 US US13/595,585 patent/US8648093B2/en not_active Expired - Lifetime
2014
- 2014-02-07 US US14/175,621 patent/US8969569B2/en not_active Expired - Lifetime
2015
- 2015-02-03 US US14/612,879 patent/US9539250B2/en not_active Expired - Lifetime
2016
- 2016-11-23 US US15/359,734 patent/US9873681B2/en not_active Expired - Lifetime
2017
- 2017-12-18 US US15/844,904 patent/US10329276B2/en not_active Expired - Lifetime
2021
- 2021-12-21 CY CY20211101121T patent/CY1125048T1/el unknown

Also Published As

Publication number	Publication date
US10329276B2 (en)	2019-06-25
EP1802607A2 (en)	2007-07-04
WO2006042034A2 (en)	2006-04-20
US20070043019A1 (en)	2007-02-22
US20170073329A1 (en)	2017-03-16
EP3957632A1 (en)	2022-02-23
US20150196547A1 (en)	2015-07-16
WO2006042034A3 (en)	2006-06-22
CA2582954A1 (en)	2006-04-20
WO2006042034A8 (en)	2007-09-07
EP3056492B1 (en)	2021-09-22
DK3056492T3 (da)	2021-12-13
US9873681B2 (en)	2018-01-23
US8648093B2 (en)	2014-02-11
ES2901955T3 (es)	2022-03-24
US9539250B2 (en)	2017-01-10
SI3056492T1 (sl)	2022-03-31
HUE056718T2 (hu)	2022-03-28
US20100261703A1 (en)	2010-10-14
US7728143B2 (en)	2010-06-01
US8969569B2 (en)	2015-03-03
JP5294633B2 (ja)	2013-09-18
EP3056492A1 (en)	2016-08-17
JP2008515910A (ja)	2008-05-15
PL3056492T3 (pl)	2022-03-21
US20100286397A1 (en)	2010-11-11
US20130060040A1 (en)	2013-03-07
US20140155380A1 (en)	2014-06-05
US8252813B2 (en)	2012-08-28
US20180105510A1 (en)	2018-04-19
CA2582954C (en)	2014-07-29
CY1125048T1 (el)	2023-06-09
PT3056492T (pt)	2021-12-27
MX2007004111A (es)	2007-06-14
US8273892B2 (en)	2012-09-25

Publication	Publication Date	Title
LT3056492T (lt)	2022-01-25	Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos
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IL181524A0 (en)	2007-07-04	Heterocyclic compounds and methods of use
IL176958A0 (en)	2006-12-10	Compounds and methods of use
ZA200703975B (en)	2009-01-28	Thiadiazole compounds and methods of use
PL370481A1 (en)	2005-05-30	Salts of valsartan
SI1802579T1 (sl)	2014-03-31	Derivati 3-arilaminopiridina
IL183245A0 (en)	2007-08-19	Process for preparing phamaceutically acceptable salts of duloxetine and intermediates thereof
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EP1812451A4 (en)	2009-10-21	COMPOUNDS AND METHODS OF USE THEREOF
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PL1802329T3 (pl)	2015-10-30	Formulacja farmaceutyczna zawierająca krystaliczną insulinę oraz rozpuszczoną insulinę
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PT1833810T (pt)	2017-12-11	Modificações cristalinas de n-alfa-(2,4,6-triisopropil-fenilsulfonil)-3-hidroxiamidino-(l)-fenilalanina-4--etoxicarbonilpiperazida e/ou seus sais
IL178201A0 (en)	2006-12-31	Pharmaceutical composition comprising a salt of mirtazapine
EP1744742A4 (en)	2008-04-16	CRYSTALLINE FORMS AND AMORPHOUS SODIUM EFAPROXIRAL
IL177451A0 (en)	2006-12-10	Crystalline forms of a pharmaceutical compound
HK1095098A (en)	2007-04-27	Pharmaceutical composition comprising a salt of mirtazapine
GB0313207D0 (en)	2003-07-16	Use of a basic curd composition and derivatives thereof
IL177990A0 (en)	2006-12-31	Rotatable head of enarthrotic prosthesis