LT3097929T - Pooperaciniai adhezijos barjerai - Google Patents

Pooperaciniai adhezijos barjerai

Info

Publication number
LT3097929T
LT3097929T LTEP16170678.3T LT16170678T LT3097929T LT 3097929 T LT3097929 T LT 3097929T LT 16170678 T LT16170678 T LT 16170678T LT 3097929 T LT3097929 T LT 3097929T
Authority
LT
Lithuania
Prior art keywords
post
adhesion barriers
operative adhesion
operative
barriers
Prior art date
Application number
LTEP16170678.3T
Other languages
English (en)
Inventor
Heike Heckroth
Hartmut Nefzger
Christian Wamprecht
Original Assignee
Adhesys Medical Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adhesys Medical Gmbh filed Critical Adhesys Medical Gmbh
Publication of LT3097929T publication Critical patent/LT3097929T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3819—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen
    • C08G18/3821—Carboxylic acids; Esters thereof with monohydroxyl compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3225—Polyamines
    • C08G18/3253—Polyamines being in latent form
    • C08G18/3256—Reaction products of polyamines with aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3225—Polyamines
    • C08G18/3253—Polyamines being in latent form
    • C08G18/3259—Reaction products of polyamines with inorganic or organic acids or derivatives thereof other than metallic salts
    • C08G18/3262—Reaction products of polyamines with inorganic or organic acids or derivatives thereof other than metallic salts with carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4244—Polycondensates having carboxylic or carbonic ester groups in the main chain containing oxygen in the form of ether groups
    • C08G18/4247—Polycondensates having carboxylic or carbonic ester groups in the main chain containing oxygen in the form of ether groups derived from polyols containing at least one ether group and polycarboxylic acids
    • C08G18/4252—Polycondensates having carboxylic or carbonic ester groups in the main chain containing oxygen in the form of ether groups derived from polyols containing at least one ether group and polycarboxylic acids derived from polyols containing polyether groups and polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C08G18/4837—Polyethers containing oxyethylene units and other oxyalkylene units
    • C08G18/4841—Polyethers containing oxyethylene units and other oxyalkylene units containing oxyethylene end groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4833—Polyethers containing oxyethylene units
    • C08G18/4837—Polyethers containing oxyethylene units and other oxyalkylene units
    • C08G18/485—Polyethers containing oxyethylene units and other oxyalkylene units containing mixed oxyethylene-oxypropylene or oxyethylene-higher oxyalkylene end groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/76—Polyisocyanates or polyisothiocyanates cyclic aromatic
    • C08G18/7614—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring
    • C08G18/7621—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring being toluene diisocyanate including isomer mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]
    • Y10T428/31594—Next to aldehyde or ketone condensation product [phenol-aldehyde, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
LTEP16170678.3T 2008-02-28 2009-02-17 Pooperaciniai adhezijos barjerai LT3097929T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20080003620 EP2095832A1 (de) 2008-02-28 2008-02-28 Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.

Publications (1)

Publication Number Publication Date
LT3097929T true LT3097929T (lt) 2020-04-10

Family

ID=39832767

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP16170678.3T LT3097929T (lt) 2008-02-28 2009-02-17 Pooperaciniai adhezijos barjerai

Country Status (18)

Country Link
US (3) US9000089B2 (lt)
EP (4) EP2095832A1 (lt)
JP (1) JP5611842B2 (lt)
KR (1) KR20100117627A (lt)
CN (1) CN101959543B (lt)
AU (1) AU2009218841A1 (lt)
BR (1) BRPI0908339A2 (lt)
CA (1) CA2716807A1 (lt)
CY (1) CY1122778T1 (lt)
DK (2) DK3097929T3 (lt)
ES (2) ES2608756T3 (lt)
HR (1) HRP20200346T1 (lt)
HU (1) HUE048940T2 (lt)
LT (1) LT3097929T (lt)
PL (1) PL3097929T3 (lt)
PT (1) PT3097929T (lt)
SI (1) SI3097929T1 (lt)
WO (1) WO2009106245A2 (lt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2011808A1 (de) * 2007-07-03 2009-01-07 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie
EP2145634A1 (de) 2008-07-17 2010-01-20 Bayer MaterialScience AG Medizinische Klebstoffe zur Stillung schwerwiegender Blutungen und Abdichtung von Leckagen
BR112012009266A2 (pt) 2009-10-21 2016-05-31 Bayer Materialscience Ag hidrogel biodegradável
DK2338529T3 (da) * 2009-12-24 2013-08-26 Hartmann Paul Ag Hydrogelmatrix med forbedrede klæbeegenskaber
EP2338528B1 (de) * 2009-12-24 2013-05-29 Paul Hartmann AG Hydrogelmatrix mit erhöhter Absorptionskapazität für Flüssigkeiten
WO2012107376A1 (de) 2011-02-09 2012-08-16 Bayer Materialscience Ag Gewebekleber auf basis aminosubstituierter triacetale
DK2673310T3 (en) 2011-02-09 2015-02-23 Medical Adhesive Revolution Gmbh Tissue adhesives based on nitrogen-modified aspartates
WO2012107385A1 (de) * 2011-02-09 2012-08-16 Bayer Materialscience Ag Bioabbaubare prepolymere
PT2673311E (pt) * 2011-02-09 2014-11-12 Bayer Materialscience Ag Adesivo para tecido à base de aspartatos trifuncionais
WO2012123425A1 (de) 2011-03-16 2012-09-20 Bayer Materialscience Ag Gewebekleber auf basis estergruppenhaltiger prepolymere
JP5873931B2 (ja) 2011-12-20 2016-03-01 メディカル・アドヒーシブ・レボリューション・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングMedical Adhesive Revolution GmbH ヒドロキシアミノポリマーおよびポリ尿素/ポリウレタン組織接着剤におけるその使用
DK3385294T3 (da) 2011-12-20 2021-02-08 Adhesys Medical Gmbh Isocyanat-funktionel præpolymer til et biologisk nedbrydeligt vævsklæbemiddel
CN110041486A (zh) * 2012-01-09 2019-07-23 阿德希西斯医疗有限公司 β-氨基酸酯改性的(天冬氨酸酯)硬化剂及其在聚脲组织粘合剂中的用途
CN109923151B (zh) 2016-11-03 2021-08-20 3M创新有限公司 有机硅共聚物、制备方法和制品
KR102347848B1 (ko) * 2017-03-06 2022-01-07 주식회사 케이씨씨 자동차용 도료 조성물
US20210039359A1 (en) * 2019-08-08 2021-02-11 Covestro Llc Flexibilized polyurethanes for flexible packaging adhesive without aromatic amine migration
WO2022013345A1 (de) * 2020-07-17 2022-01-20 Adhesys Medical Gmbh Kit aus einem zwei-komponenten gewebekleber und einer textilen struktur zur stärkung des bindegewebes nach einer operation sowie dessen verwendung
CN111944115B (zh) * 2020-08-27 2023-01-06 深圳飞扬骏研新材料股份有限公司 一种聚天门冬氨酸酯预聚体及其制备方法、及相应涂料
CN117776943B (zh) * 2023-12-25 2026-02-06 北新嘉宝莉涂料集团股份有限公司 一种聚天门冬氨酸酯的合成方法及其应用和一种聚脲涂料
CN118006274B (zh) * 2024-02-04 2025-04-11 浙江巅峰建材有限公司 一种环氧树脂改性天冬聚脲美缝剂的制备方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
DE2550860C2 (de) * 1975-11-12 1983-05-26 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von stabilen Dispersionen
DE2638759A1 (de) * 1976-08-27 1978-03-09 Bayer Ag Loesungen von polyisocyanat-polyadditionsprodukten
US4532134A (en) 1981-04-06 1985-07-30 Malette William Graham Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound
SE456346B (sv) 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4701480A (en) * 1985-09-23 1987-10-20 Mobay Corporation Stable, aqueous dispersions of polyurethane-ureas
US4911926A (en) 1988-11-16 1990-03-27 Mediventures Inc. Method and composition for reducing postsurgical adhesions
US5681576A (en) 1988-11-16 1997-10-28 Mdv Technologies, Inc. Method and composition for post surgical adhesion reduction
US5135751A (en) 1988-11-16 1992-08-04 Mediventures Incorporated Composition for reducing postsurgical adhesions
ES2062188T3 (es) * 1989-06-23 1994-12-16 Bayer Ag Procedimiento para la elaboracion de revestimientos.
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
US4994277A (en) 1989-10-31 1991-02-19 Pfizer Hospital Products Group, Inc. Use of xanthan gum for preventing adhesions
US5093319A (en) 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
US5246698A (en) 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5605938A (en) 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
JP2855307B2 (ja) 1992-02-05 1999-02-10 生化学工業株式会社 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
US5243012A (en) 1992-06-10 1993-09-07 Miles Inc. Polyurea coating compositions having improved pot lives
US5266326A (en) 1992-06-30 1993-11-30 Pfizer Hospital Products Group, Inc. In situ modification of alginate
US5466771A (en) * 1993-12-21 1995-11-14 Bayer Corporation Coating compositions based on aldimines and polyisocyanates containing allophanate groups
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US5674942A (en) * 1995-03-31 1997-10-07 Johnson & Johnson Vision Products, Inc. Interpenetrating polymer networks for contact lens production
US5612052A (en) 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6551610B2 (en) 1995-04-13 2003-04-22 Poly-Med, Inc. Multifaceted compositions for post-surgical adhesion prevention
US6413539B1 (en) 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US5679658A (en) 1995-05-08 1997-10-21 Chitogenics, Inc. N,O-carbonxymethylchitosan for prevention of surgical adhesions
US5605939A (en) * 1996-01-26 1997-02-25 Arco Chemical Technology, L.P. Poly(oxypropylene/oxyethylene) random polyols useful in preparing flexible high resilience foam with reduced tendencies toward shrinkage and foam prepared therewith
US5711958A (en) 1996-07-11 1998-01-27 Life Medical Sciences, Inc. Methods for reducing or eliminating post-surgical adhesion formation
US6013755A (en) * 1997-03-11 2000-01-11 Huntsman Petrochemical Corporation Method of preparing an aliphatic polyurea spray elastomer system
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6063863A (en) * 1998-12-23 2000-05-16 Bayer Corporation Aqueous compositions containing colloidal silica and compounds with alkoxysilane and/or silanol groups
DE19914879A1 (de) * 1999-04-01 2000-10-05 Bayer Ag Polyurethanlösungen mit Alkoxysilanstruktureinheiten
US6174984B1 (en) * 1999-06-14 2001-01-16 Uniroyal Chemical Company, Inc. Clear, resilient polyurethane elastomers
US6355829B2 (en) 1999-09-02 2002-03-12 Bayer Corporation Aspartate-terminated urea/urethane prepolymers and their use in coating compositions
US6586483B2 (en) * 2001-01-08 2003-07-01 3M Innovative Properties Company Foam including surface-modified nanoparticles
US7001948B2 (en) * 2001-05-16 2006-02-21 American Polymer Corporation Polyurea coating compositions
EP2462939A3 (en) 2001-07-31 2012-08-15 Tyco Healthcare Group LP Bioabsorbable adhesive compounds and compositions
US20040068078A1 (en) 2001-12-12 2004-04-08 Milbocker Michael T. In situ polymerizing medical compositions
WO2004021983A2 (en) 2002-09-03 2004-03-18 Promethean Surgical Devices Llc In situ polymerizing medical compositions
DE10246708A1 (de) 2002-10-07 2004-04-15 Bayer Ag Zweikomponenten-Systeme für die Herstellung elastischer Beschichtungen
US20040167255A1 (en) * 2003-01-14 2004-08-26 Everlight Usa, Inc. Stabilizer composition
US20050175659A1 (en) 2004-02-09 2005-08-11 Macomber Laurel R. Collagen device and method of preparing the same
US20050266086A1 (en) 2004-06-01 2005-12-01 Sawhney Amarpreet S Intrauterine applications of materials formed in situ
US20050271727A1 (en) 2004-06-07 2005-12-08 Callisyn Pharmaceuticals, Inc. Biodegradable and biocompatible crosslinked polymer hydrogel prepared from PVA and/or PEG macromer mixtures
CA2574933C (en) 2004-07-26 2015-05-19 Synthes (U.S.A.) Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio
US8044234B2 (en) 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20070100112A1 (en) * 2005-10-27 2007-05-03 Bayer Materialscience Llc Polyurethane-urea elastomers
EP1960469B1 (en) * 2005-12-06 2016-07-13 Covidien LP Bioabsorbable compounds and compositions containing them
US8703167B2 (en) * 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
DE102007025659A1 (de) * 2007-06-01 2008-12-11 Bayer Materialscience Ag NCO-Prepolymere mit niedrigem Gehalt an freiem monomerem Diisocyanat und ihre Herstellung
EP2011808A1 (de) * 2007-07-03 2009-01-07 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie
US8772407B2 (en) * 2007-09-17 2014-07-08 Ppg Industries Ohio, Inc. One component polysiloxane coating compositions and related coated substrates
EP2083025A1 (de) * 2008-01-24 2009-07-29 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie

Also Published As

Publication number Publication date
CY1122778T1 (el) 2021-05-05
CN101959543B (zh) 2015-01-28
EP2259808B1 (de) 2016-09-28
ES2772924T3 (es) 2020-07-08
HUE048940T2 (hu) 2020-09-28
ES2608756T3 (es) 2017-04-12
DK3097929T3 (da) 2020-02-24
AU2009218841A1 (en) 2009-09-03
HRP20200346T1 (hr) 2020-06-12
PT3097929T (pt) 2020-03-06
JP2011514413A (ja) 2011-05-06
EP3653235A1 (de) 2020-05-20
US20090221071A1 (en) 2009-09-03
US20200223973A1 (en) 2020-07-16
SI3097929T1 (sl) 2020-04-30
EP3097929B1 (de) 2020-01-15
EP3097929A1 (de) 2016-11-30
US10633481B2 (en) 2020-04-28
EP2259808A2 (de) 2010-12-15
CN101959543A (zh) 2011-01-26
JP5611842B2 (ja) 2014-10-22
US9000089B2 (en) 2015-04-07
DK2259808T3 (en) 2017-01-23
PL3097929T3 (pl) 2020-06-29
BRPI0908339A2 (pt) 2015-08-04
WO2009106245A3 (de) 2010-06-17
CA2716807A1 (en) 2009-09-03
KR20100117627A (ko) 2010-11-03
EP2095832A1 (de) 2009-09-02
US20150166715A1 (en) 2015-06-18
WO2009106245A2 (de) 2009-09-03

Similar Documents

Publication Publication Date Title
HUE048940T2 (hu) Posztoperatív tapadásgátlók
GB0814304D0 (en) Asphalt rejuenation
ZA200808637B (en) Polymers
GB0812185D0 (en) Polymers modified by silanes
GB0817391D0 (en) Direction estimate
EP2026825A4 (en) FURANON-INITIATED POLYMERS
GB2459193B (en) Adhesion improver
GB0604911D0 (en) Polymers
GB2462354B (en) Barrier
GB0908014D0 (en) Paving
GB0816532D0 (en) Barrier
TWI370472B (en) Press-button
PL121333U1 (pl) Futryna
AU2008905604A0 (en) Barrier
AU2008903011A0 (en) Barrier
AU2008903062A0 (en) Barrier
GB0617918D0 (en) Polymers
AU322513S (en) Door stop
GB0811679D0 (en) Panellised Building
AU2008902089A0 (en) Sleeper unit
PH32008000218S1 (en) Road barrier
AU323519S (en) Barrier
AU323520S (en) Barrier
GB0801505D0 (en) Barrier
GB0814313D0 (en) Barrier