LT3709996T - Kumarino darinys, skirtas ląstelių proliferacijos sutrikimo terapijai arba profilaktikai - Google Patents

Kumarino darinys, skirtas ląstelių proliferacijos sutrikimo terapijai arba profilaktikai

Info

Publication number
LT3709996T
LT3709996T LTEPPCT/EP2018/062805T LTEP2018062805T LT3709996T LT 3709996 T LT3709996 T LT 3709996T LT EP2018062805 T LTEP2018062805 T LT EP2018062805T LT 3709996 T LT3709996 T LT 3709996T
Authority
LT
Lithuania
Prior art keywords
prophylaxis
therapy
cell proliferation
coumarin derivative
proliferation disorders
Prior art date
Application number
LTEPPCT/EP2018/062805T
Other languages
English (en)
Inventor
Udai BANERJI
Original Assignee
The Institute Of Cancer Research: Royal Cancer Hospital
The Royal Marsden Nhs Foundation Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Institute Of Cancer Research: Royal Cancer Hospital, The Royal Marsden Nhs Foundation Trust filed Critical The Institute Of Cancer Research: Royal Cancer Hospital
Publication of LT3709996T publication Critical patent/LT3709996T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEPPCT/EP2018/062805T 2017-11-16 2018-05-16 Kumarino darinys, skirtas ląstelių proliferacijos sutrikimo terapijai arba profilaktikai LT3709996T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2017/079506 WO2019096397A1 (en) 2017-11-16 2017-11-16 Coumarin derivative for therapy or prophylaxis of a cell proliferative disorder
PCT/EP2018/062805 WO2019096449A1 (en) 2017-11-16 2018-05-16 Coumarin derivative for therapy or prophylaxis of a cell proliferative disorder

Publications (1)

Publication Number Publication Date
LT3709996T true LT3709996T (lt) 2024-06-25

Family

ID=60331633

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2018/062805T LT3709996T (lt) 2017-11-16 2018-05-16 Kumarino darinys, skirtas ląstelių proliferacijos sutrikimo terapijai arba profilaktikai

Country Status (22)

Country Link
US (3) US11400090B2 (lt)
EP (2) EP3709996B1 (lt)
KR (3) KR20250159077A (lt)
CN (1) CN111542317A (lt)
AU (2) AU2018369325B2 (lt)
BR (1) BR112020009452A2 (lt)
CA (1) CA3082619A1 (lt)
DK (1) DK3709996T3 (lt)
ES (1) ES2975294T3 (lt)
FI (1) FI3709996T3 (lt)
HR (1) HRP20240400T1 (lt)
HU (1) HUE066867T2 (lt)
LT (1) LT3709996T (lt)
MX (2) MX2020005006A (lt)
PL (1) PL3709996T3 (lt)
PT (1) PT3709996T (lt)
RS (1) RS65501B1 (lt)
RU (1) RU2760006C1 (lt)
SG (1) SG11202004376TA (lt)
SI (1) SI3709996T1 (lt)
TW (1) TWI795405B (lt)
WO (2) WO2019096397A1 (lt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2760006C1 (ru) 2017-11-16 2021-11-22 Дзе Инститьют оф Кансер Рисерч: Ройал Кансер Хоспитал Производное кумарина для лечения или профилактики расстройства пролиферации клеток
JP2022547358A (ja) 2019-09-13 2022-11-14 ジ インスティテュート オブ キャンサー リサーチ：ロイヤル キャンサー ホスピタル 治療組成物、組み合わせ、及び使用方法
AU2021206684B2 (en) 2020-01-10 2024-01-18 Immuneering Corporation MEK inhibitors and therapeutic uses thereof
CN118647382A (zh) * 2021-11-02 2024-09-13 维瑞斯特姆股份有限公司 治疗异常细胞生长的方法
US11873296B2 (en) * 2022-06-07 2024-01-16 Verastem, Inc. Solid forms of a dual RAF/MEK inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920908D0 (en) * 1999-09-03 1999-11-10 Indena Spa Chalcone coumarins
AR059339A1 (es) 2006-02-09 2008-03-26 Chugai Pharmaceutical Co Ltd Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene
US8569378B2 (en) 2007-07-20 2013-10-29 Toshiyuki Sakai p27 protein inducer
CN103458970A (zh) * 2011-03-07 2013-12-18 泰莱托恩基金会 Tfeb磷酸化抑制剂及其应用
EP2754654B1 (en) 2011-09-05 2018-05-30 Chugai Seiyaku Kabushiki Kaisha Method for producing coumarin derivative
RU2760006C1 (ru) 2017-11-16 2021-11-22 Дзе Инститьют оф Кансер Рисерч: Ройал Кансер Хоспитал Производное кумарина для лечения или профилактики расстройства пролиферации клеток

Also Published As

Publication number Publication date
US20250345331A1 (en) 2025-11-13
KR20240093888A (ko) 2024-06-24
HRP20240400T1 (hr) 2024-08-30
AU2024219534A1 (en) 2024-10-03
KR20200096538A (ko) 2020-08-12
TWI795405B (zh) 2023-03-11
HUE066867T2 (hu) 2024-09-28
AU2018369325A1 (en) 2020-06-18
ES2975294T3 (es) 2024-07-04
EP3709996A1 (en) 2020-09-23
AU2018369325B2 (en) 2024-09-12
FI3709996T3 (fi) 2024-03-22
PL3709996T3 (pl) 2024-09-02
KR102669822B1 (ko) 2024-05-28
KR20250159077A (ko) 2025-11-07
TW201922254A (zh) 2019-06-16
MX2020005006A (es) 2020-10-12
US20210330670A1 (en) 2021-10-28
SG11202004376TA (en) 2020-06-29
SI3709996T1 (sl) 2024-08-30
BR112020009452A2 (pt) 2020-12-22
CA3082619A1 (en) 2019-05-23
US20230012116A1 (en) 2023-01-12
EP4364807A3 (en) 2024-08-14
EP4364807A2 (en) 2024-05-08
PT3709996T (pt) 2024-04-15
EP3709996B1 (en) 2024-02-28
US12390465B2 (en) 2025-08-19
US11400090B2 (en) 2022-08-02
WO2019096449A1 (en) 2019-05-23
RU2760006C1 (ru) 2021-11-22
CN111542317A (zh) 2020-08-14
RS65501B1 (sr) 2024-06-28
MX2023011203A (es) 2023-10-02
DK3709996T3 (da) 2024-03-11
WO2019096397A1 (en) 2019-05-23

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