LU79891A1 - Procede de culture de virus - Google Patents

Procede de culture de virus Download PDF

Info

Publication number: LU79891A1
Authority: LU; Luxembourg
Prior art keywords: culture; virus; carried out; fermenter; cells
Prior art date: 1977-06-30

Application number

LU79891A

Other languages

English (en)

French (fr)

Inventor

G Zwingelstein

M Bugand

P Precausta

P Comte

Original Assignee

Merieux Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-06-30

Filing date

1978-06-29

Publication date

1980-01-22

1978-06-29 Application filed by Merieux Inst filed Critical Merieux Inst

1980-01-22 Publication of LU79891A1 publication Critical patent/LU79891A1/fr

Links

241000700605 Viruses Species 0.000 title claims description 18
238000000034 method Methods 0.000 title claims description 17
239000000835 fiber Substances 0.000 claims description 24
239000000725 suspension Substances 0.000 claims description 22
102000008186 Collagen Human genes 0.000 claims description 14
108010035532 Collagen Proteins 0.000 claims description 14
229920001436 collagen Polymers 0.000 claims description 14
238000003756 stirring Methods 0.000 claims description 10
239000006228 supernatant Substances 0.000 claims description 10
235000015097 nutrients Nutrition 0.000 claims description 9
241000711798 Rabies lyssavirus Species 0.000 claims description 7
230000006978 adaptation Effects 0.000 claims description 3
238000012136 culture method Methods 0.000 claims description 2
101100245379 Arabidopsis thaliana PBF1 gene Proteins 0.000 claims 1
238000010899 nucleation Methods 0.000 claims 1
238000009331 sowing Methods 0.000 claims 1
238000005273 aeration Methods 0.000 description 11
230000003612 virological effect Effects 0.000 description 8
238000013019 agitation Methods 0.000 description 6
108090000631 Trypsin Proteins 0.000 description 4
102000004142 Trypsin Human genes 0.000 description 4
239000012528 membrane Substances 0.000 description 4
230000000050 nutritive effect Effects 0.000 description 4
238000002360 preparation method Methods 0.000 description 4
239000012588 trypsin Substances 0.000 description 4
239000007788 liquid Substances 0.000 description 3
210000002966 serum Anatomy 0.000 description 3
230000001954 sterilising effect Effects 0.000 description 3
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
206010037742 Rabies Diseases 0.000 description 2
239000000427 antigen Substances 0.000 description 2
108091007433 antigens Proteins 0.000 description 2
102000036639 antigens Human genes 0.000 description 2
VEZXCJBBBCKRPI-UHFFFAOYSA-N beta-propiolactone Chemical compound O=C1CCO1 VEZXCJBBBCKRPI-UHFFFAOYSA-N 0.000 description 2
239000006285 cell suspension Substances 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
229960000380 propiolactone Drugs 0.000 description 2
238000003860 storage Methods 0.000 description 2
229960005486 vaccine Drugs 0.000 description 2
241000283690 Bos taurus Species 0.000 description 1
241000699800 Cricetinae Species 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
108091005804 Peptidases Proteins 0.000 description 1
102000035195 Peptidases Human genes 0.000 description 1
239000001888 Peptone Substances 0.000 description 1
108010080698 Peptones Proteins 0.000 description 1
108010059712 Pronase Proteins 0.000 description 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
239000002671 adjuvant Substances 0.000 description 1
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
229940024606 amino acid Drugs 0.000 description 1
235000001014 amino acid Nutrition 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
230000002528 anti-freeze Effects 0.000 description 1
244000309466 calf Species 0.000 description 1
229940077731 carbohydrate nutrients Drugs 0.000 description 1
235000014633 carbohydrates Nutrition 0.000 description 1
150000001720 carbohydrates Chemical class 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
238000004113 cell culture Methods 0.000 description 1
230000001413 cellular effect Effects 0.000 description 1
239000000470 constituent Substances 0.000 description 1
238000012258 culturing Methods 0.000 description 1
230000009089 cytolysis Effects 0.000 description 1
238000010908 decantation Methods 0.000 description 1
210000004207 dermis Anatomy 0.000 description 1
AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 1
210000002257 embryonic structure Anatomy 0.000 description 1
238000004108 freeze drying Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
238000011534 incubation Methods 0.000 description 1
238000009776 industrial production Methods 0.000 description 1
239000008101 lactose Substances 0.000 description 1
239000010985 leather Substances 0.000 description 1
229960005030 other vaccine in atc Drugs 0.000 description 1
235000019319 peptone Nutrition 0.000 description 1
229940066779 peptones Drugs 0.000 description 1
229960003127 rabies vaccine Drugs 0.000 description 1
210000003491 skin Anatomy 0.000 description 1
239000000758 substrate Substances 0.000 description 1
238000011282 treatment Methods 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
239000011782 vitamin Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20151—Methods of production or purification of viral material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Mycology (AREA)
Public Health (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

LU79891A 1977-06-30 1978-06-29 Procede de culture de virus LU79891A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7720115		1977-06-30
FR7720115A FR2396083A1 (fr)	1977-06-30	1977-06-30	Procede de culture de virus

Publications (1)

Publication Number	Publication Date
LU79891A1 true LU79891A1 (fr)	1980-01-22

Family

ID=9192781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU79891A LU79891A1 (fr)	1977-06-30	1978-06-29	Procede de culture de virus

Country Status (11)

Country	Link
US (1)	US4169761A (it)
AR (1)	AR216331A1 (it)
BE (1)	BE868573A (it)
DE (1)	DE2828073C2 (it)
DK (1)	DK147889C (it)
FR (1)	FR2396083A1 (it)
GB (1)	GB1604003A (it)
IE (1)	IE47060B1 (it)
IT (1)	IT1097352B (it)
LU (1)	LU79891A1 (it)
NL (1)	NL7806899A (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE456164B (sv) *	1980-08-20	1988-09-12	Kjell Nilsson	Forfarande for immobilisering, odling och efterfoljande frigoring av animala celler samt mikroberare av gelatin med absorberade animala celler
JPS5832876B2 (ja) *	1981-03-27	1983-07-15	呉羽化学工業株式会社	組織培養基材
JPS5928472A (ja) *	1982-08-09	1984-02-15	Koken:Kk	細胞培養用基質およびこの基質を用いた細胞培養・分離法
US4560655A (en) *	1982-12-16	1985-12-24	Immunex Corporation	Serum-free cell culture medium and process for making same
SE454518B (sv) *	1984-05-21	1988-05-09	Statens Bakteriologiska Lab	Forfarande for odling av diploida celler i nervaro av cellulosafibrer
US4748121A (en) *	1984-11-30	1988-05-31	Ppg Industries, Inc.	Porous glass fibers with immobilized biochemically active material
US4861714A (en) *	1985-04-04	1989-08-29	Verax Corporation	Weighted collagen microsponge for immobilizing bioactive material
US5100783A (en) *	1985-05-10	1992-03-31	Verax Corporation	Weighted microsponge for immobilizing bioactive material
DE3526809A1 (de) *	1985-07-26	1987-04-02	Behringwerke Ag	Tollwut-lebendimpfstoff
EP0513803A2 (en) *	1991-05-17	1992-11-19	Japan Vilene Company, Ltd.	Carrier for immobilization of animal cells, process for manufacture thereof, and methods for cultivation

1977
- 1977-06-30 FR FR7720115A patent/FR2396083A1/fr active Granted
1978
- 1978-05-30 GB GB24289/78A patent/GB1604003A/en not_active Expired
- 1978-06-23 US US05/918,962 patent/US4169761A/en not_active Expired - Lifetime
- 1978-06-27 IT IT25037/78A patent/IT1097352B/it active
- 1978-06-27 DE DE2828073A patent/DE2828073C2/de not_active Expired
- 1978-06-27 DK DK289378A patent/DK147889C/da active
- 1978-06-27 NL NL7806899A patent/NL7806899A/xx not_active Application Discontinuation
- 1978-06-29 BE BE188933A patent/BE868573A/xx not_active IP Right Cessation
- 1978-06-29 AR AR272761A patent/AR216331A1/es active
- 1978-06-29 LU LU79891A patent/LU79891A1/fr unknown
- 1978-06-29 IE IE1315/78A patent/IE47060B1/en unknown

Also Published As

Publication number	Publication date
FR2396083A1 (fr)	1979-01-26
DK147889B (da)	1985-01-02
NL7806899A (nl)	1979-01-03
IE47060B1 (en)	1983-12-14
FR2396083B1 (it)	1980-03-07
GB1604003A (en)	1981-12-02
US4169761A (en)	1979-10-02
IT7825037A0 (it)	1978-06-27
IT1097352B (it)	1985-08-31
IE781315L (en)	1978-12-30
BE868573A (fr)	1978-12-29
DE2828073C2 (de)	1983-05-05
DK289378A (da)	1978-12-31
DK147889C (da)	1985-06-10
AR216331A1 (es)	1979-12-14
DE2828073A1 (de)	1979-01-11

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