LU80437A1 - Procede et dispositif pour le dosage de la malondialdehyde - Google Patents

Procede et dispositif pour le dosage de la malondialdehyde Download PDF

Info

Publication number: LU80437A1
Authority: LU; Luxembourg
Prior art keywords: malondialdehyde; determination; platelets; samples; acid
Prior art date: 1978-10-27

Application number

LU80437A

Other languages

English (en)

French (fr)

Inventor

R Roncucci

J Lansen

Original Assignee

Continental Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-10-27

Filing date

1978-10-27

Publication date

1980-05-07

1978-10-27 Application filed by Continental Pharma filed Critical Continental Pharma

1978-10-27 Priority to LU80437A priority Critical patent/LU80437A1/fr

1979-10-22 Priority to DE2942617A priority patent/DE2942617C2/de

1979-10-22 Priority to FI793270A priority patent/FI71431C/fi

1979-10-23 Priority to NL7907787A priority patent/NL7907787A/nl

1979-10-24 Priority to SE7908794A priority patent/SE441548B/sv

1979-10-24 Priority to GB7936880A priority patent/GB2036310B/en

1979-10-25 Priority to IT26792/79A priority patent/IT1125601B/it

1979-10-26 Priority to BE0/197844A priority patent/BE879668A/fr

1979-10-26 Priority to FR7926684A priority patent/FR2439996A1/fr

1979-10-26 Priority to DK452879A priority patent/DK452879A/da

1979-10-26 Priority to US06/088,726 priority patent/US4318706A/en

1979-10-26 Priority to CH963779A priority patent/CH632845A5/fr

1979-10-26 Priority to IN1111/CAL/79A priority patent/IN151553B/en

1979-10-26 Priority to CA000338590A priority patent/CA1121702A/en

1979-10-26 Priority to JP13785079A priority patent/JPS5589751A/ja

1979-10-26 Priority to AR278640A priority patent/AR225295A1/es

1979-10-26 Priority to NO793463A priority patent/NO154287C/no

1979-10-26 Priority to MX179809A priority patent/MX153877A/es

1980-05-07 Publication of LU80437A1 publication Critical patent/LU80437A1/fr

Links

229940118019 malondialdehyde Drugs 0.000 title claims description 36
WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical compound O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 title claims description 35
238000000034 method Methods 0.000 title claims description 11
210000001772 blood platelet Anatomy 0.000 claims description 26
238000000502 dialysis Methods 0.000 claims description 11
RVBUGGBMJDPOST-UHFFFAOYSA-N 2-thiobarbituric acid Chemical compound O=C1CC(=O)NC(=S)N1 RVBUGGBMJDPOST-UHFFFAOYSA-N 0.000 claims description 8
YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims description 6
238000004519 manufacturing process Methods 0.000 claims description 5
229940114079 arachidonic acid Drugs 0.000 claims description 3
235000021342 arachidonic acid Nutrition 0.000 claims description 3
210000004369 blood Anatomy 0.000 claims description 3
239000008280 blood Substances 0.000 claims description 3
239000003795 chemical substances by application Substances 0.000 claims description 2
238000004737 colorimetric analysis Methods 0.000 claims description 2
239000012530 fluid Substances 0.000 claims description 2
230000002572 peristaltic effect Effects 0.000 claims description 2
239000008363 phosphate buffer Substances 0.000 claims description 2
PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 claims 1
230000004931 aggregating effect Effects 0.000 claims 1
239000003153 chemical reaction reagent Substances 0.000 claims 1
101150006061 neur gene Proteins 0.000 claims 1
230000004936 stimulating effect Effects 0.000 claims 1
VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 32
239000000243 solution Substances 0.000 description 10
239000002253 acid Substances 0.000 description 6
BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 5
229960001138 acetylsalicylic acid Drugs 0.000 description 5
102000004169 proteins and genes Human genes 0.000 description 5
108090000623 proteins and genes Proteins 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
238000003556 assay Methods 0.000 description 3
238000002156 mixing Methods 0.000 description 3
230000035945 sensitivity Effects 0.000 description 3
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
HDFGOPSGAURCEO-UHFFFAOYSA-N N-ethylmaleimide Chemical compound CCN1C(=O)C=CC1=O HDFGOPSGAURCEO-UHFFFAOYSA-N 0.000 description 2
102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 description 2
108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 description 2
238000005119 centrifugation Methods 0.000 description 2
238000010586 diagram Methods 0.000 description 2
238000011534 incubation Methods 0.000 description 2
239000000203 mixture Substances 0.000 description 2
125000000896 monocarboxylic acid group Chemical group 0.000 description 2
239000008188 pellet Substances 0.000 description 2
230000008929 regeneration Effects 0.000 description 2
238000011069 regeneration method Methods 0.000 description 2
238000005070 sampling Methods 0.000 description 2
DSPDJPFEBQTXDO-UHFFFAOYSA-N 1-[2-(3-pyrrolidin-1-ylprop-1-ynyl)piperidin-1-yl]ethanone Chemical compound CC(=O)N1CCCCC1C#CCN1CCCC1 DSPDJPFEBQTXDO-UHFFFAOYSA-N 0.000 description 1
IEQAICDLOKRSRL-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO IEQAICDLOKRSRL-UHFFFAOYSA-N 0.000 description 1
BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 description 1
206010011224 Cough Diseases 0.000 description 1
GHAZCVNUKKZTLG-UHFFFAOYSA-N N-ethyl-succinimide Natural products CCN1C(=O)CCC1=O GHAZCVNUKKZTLG-UHFFFAOYSA-N 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000003321 amplification Effects 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
230000033228 biological regulation Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000001185 bone marrow Anatomy 0.000 description 1
230000005587 bubbling Effects 0.000 description 1
238000011088 calibration curve Methods 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
238000004040 coloring Methods 0.000 description 1
230000007797 corrosion Effects 0.000 description 1
238000005260 corrosion Methods 0.000 description 1
230000006378 damage Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
238000007865 diluting Methods 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
239000008240 homogeneous mixture Substances 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
238000005259 measurement Methods 0.000 description 1
239000012528 membrane Substances 0.000 description 1
230000002503 metabolic effect Effects 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
230000004048 modification Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
239000010413 mother solution Substances 0.000 description 1
238000003199 nucleic acid amplification method Methods 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
238000010186 staining Methods 0.000 description 1
230000029305 taxis Effects 0.000 description 1
230000009466 transformation Effects 0.000 description 1
HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
229940038773 trisodium citrate Drugs 0.000 description 1
238000002604 ultrasonography Methods 0.000 description 1
238000005406 washing Methods 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

LU80437A 1978-10-27 1978-10-27 Procede et dispositif pour le dosage de la malondialdehyde LU80437A1 (fr)

Priority Applications (18)

Application Number	Priority Date	Filing Date	Title
LU80437A LU80437A1 (fr)	1978-10-27	1978-10-27	Procede et dispositif pour le dosage de la malondialdehyde
DE2942617A DE2942617C2 (de)	1978-10-27	1979-10-22	Verfahren und Vorrichtung zur quantitativen Bestimmung des Malondialdehyds von Blutplättchen
FI793270A FI71431C (fi)	1978-10-27	1979-10-22	Foerfarande foer bestaemning av malondialdehyd
NL7907787A NL7907787A (nl)	1978-10-27	1979-10-23	Werkwijze en inrichting voor de bepaling van malondialdehyde.
SE7908794A SE441548B (sv)	1978-10-27	1979-10-24	Forfaringssett for kvantitativ bestemning av malondialdehyd i blodplettar
GB7936880A GB2036310B (en)	1978-10-27	1979-10-24	Process and apparatus for determination of malondialdehyde
IT26792/79A IT1125601B (it)	1978-10-27	1979-10-25	Procedimento e dispositivo per il dosaggio della dialdeide malonica
BE0/197844A BE879668A (fr)	1978-10-27	1979-10-26	Procede et dispositif pour le dosage du dialdehyde malonique.
FR7926684A FR2439996A1 (fr)	1978-10-27	1979-10-26	Procede et dispositif pour le dosage du dialdehyde malonique
DK452879A DK452879A (da)	1978-10-27	1979-10-26	Fremgangsmaade og apparat til bestemmelse af malondialdehyd ved titrering
US06/088,726 US4318706A (en)	1978-10-27	1979-10-26	Process for determining malondialdehyde
CH963779A CH632845A5 (fr)	1978-10-27	1979-10-26	Procede et dispositif pour le dosage du dialdehyde malonique de plaquettes sanguines.
IN1111/CAL/79A IN151553B (da)	1978-10-27	1979-10-26
CA000338590A CA1121702A (en)	1978-10-27	1979-10-26	Process and apparatus for proportioning malondialdehyde
JP13785079A JPS5589751A (en)	1978-10-27	1979-10-26	Method and apparatus for measuring malondialdehyde
AR278640A AR225295A1 (es)	1978-10-27	1979-10-26	Dispositivo mejorado para determinar malondialdehido
NO793463A NO154287C (no)	1978-10-27	1979-10-26	Fremgangsmaate ved bestemmelse av malondialdehyd.
MX179809A MX153877A (es)	1978-10-27	1979-10-26	Aparato para cuantificar malondialdehido a partir de las plaquetas de la sangre

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
LU80437A LU80437A1 (fr)	1978-10-27	1978-10-27	Procede et dispositif pour le dosage de la malondialdehyde
LU80437		1978-10-27

Publications (1)

Publication Number	Publication Date
LU80437A1 true LU80437A1 (fr)	1980-05-07

Family

ID=19729031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU80437A LU80437A1 (fr)	1978-10-27	1978-10-27	Procede et dispositif pour le dosage de la malondialdehyde

Country Status (18)

Country	Link
US (1)	US4318706A (da)
JP (1)	JPS5589751A (da)
AR (1)	AR225295A1 (da)
BE (1)	BE879668A (da)
CA (1)	CA1121702A (da)
CH (1)	CH632845A5 (da)
DE (1)	DE2942617C2 (da)
DK (1)	DK452879A (da)
FI (1)	FI71431C (da)
FR (1)	FR2439996A1 (da)
GB (1)	GB2036310B (da)
IN (1)	IN151553B (da)
IT (1)	IT1125601B (da)
LU (1)	LU80437A1 (da)
MX (1)	MX153877A (da)
NL (1)	NL7907787A (da)
NO (1)	NO154287C (da)
SE (1)	SE441548B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5205988A (en) *	1989-04-06	1993-04-27	Nihon Bunko Kogyo Kabushiki Kaisha	Apparatus for measuring gaseous aldehyde
FR2800874B1 (fr) *	1999-11-09	2001-12-21	Jean Morelle	Procede permettant de mettre rapidement en evidence le malondialdehyde (mda) dans l'urine, dans les produits alimentaires et cosmetiques
KR102614951B1 (ko) *	2015-12-10	2023-12-19	삼성전자주식회사	색상 변화로 검출 대상의 농도를 측정하기 위한 패드를 제조하는 방법, 그 패드 제작용 용액 및 그 패드를 이용한 스트립

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2797149A (en) *	1953-01-08	1957-06-25	Technicon International Ltd	Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
DE1065635B (da)	1956-03-23
NL130069C (da)	1962-09-07
US3804593A (en) *	1964-05-25	1974-04-16	Technicon Instr	Automatic analysis apparatus and method
US3604814A (en) *	1969-06-20	1971-09-14	Technicon Corp	Method and apparatus for the sequential analysis of fluid samples
JPS5014147A (da) *	1973-06-08	1975-02-14
US3876374A (en) *	1974-03-22	1975-04-08	Technicon Instr	Method and apparatus for automated quantitative fluid analysis
SE396819B (sv) *	1975-12-31	1977-10-03	Gambro Ab	Sett och anordning for bestemning av koncentrationen av en lagmolekyler forening i ett komplext medium genom dialys

1978
- 1978-10-27 LU LU80437A patent/LU80437A1/fr unknown
1979
- 1979-10-22 DE DE2942617A patent/DE2942617C2/de not_active Expired
- 1979-10-22 FI FI793270A patent/FI71431C/fi not_active IP Right Cessation
- 1979-10-23 NL NL7907787A patent/NL7907787A/nl not_active Application Discontinuation
- 1979-10-24 GB GB7936880A patent/GB2036310B/en not_active Expired
- 1979-10-24 SE SE7908794A patent/SE441548B/sv not_active IP Right Cessation
- 1979-10-25 IT IT26792/79A patent/IT1125601B/it active
- 1979-10-26 DK DK452879A patent/DK452879A/da not_active Application Discontinuation
- 1979-10-26 BE BE0/197844A patent/BE879668A/fr not_active IP Right Cessation
- 1979-10-26 US US06/088,726 patent/US4318706A/en not_active Expired - Lifetime
- 1979-10-26 MX MX179809A patent/MX153877A/es unknown
- 1979-10-26 IN IN1111/CAL/79A patent/IN151553B/en unknown
- 1979-10-26 CA CA000338590A patent/CA1121702A/en not_active Expired
- 1979-10-26 NO NO793463A patent/NO154287C/no unknown
- 1979-10-26 JP JP13785079A patent/JPS5589751A/ja active Pending
- 1979-10-26 AR AR278640A patent/AR225295A1/es active
- 1979-10-26 FR FR7926684A patent/FR2439996A1/fr active Granted
- 1979-10-26 CH CH963779A patent/CH632845A5/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO154287B (no)	1986-05-12
SE441548B (sv)	1985-10-14
FI793270A7 (fi)	1980-04-28
DE2942617A1 (de)	1980-05-08
FI71431C (fi)	1986-12-19
IT1125601B (it)	1986-05-14
FI71431B (fi)	1986-09-09
JPS5589751A (en)	1980-07-07
GB2036310B (en)	1983-03-02
BE879668A (fr)	1980-04-28
GB2036310A (en)	1980-06-25
NO154287C (no)	1986-08-20
DK452879A (da)	1980-04-28
DE2942617C2 (de)	1983-12-29
IT7926792A0 (it)	1979-10-25
AR225295A1 (es)	1982-03-15
FR2439996A1 (fr)	1980-05-23
NL7907787A (nl)	1980-04-29
IN151553B (da)	1983-05-21
SE7908794L (sv)	1980-04-28
MX153877A (es)	1987-01-30
CH632845A5 (fr)	1982-10-29
FR2439996B1 (da)	1984-11-16
US4318706A (en)	1982-03-09
CA1121702A (en)	1982-04-13
NO793463L (no)	1980-04-29

Legal Events

Date	Code	Title	Description
1991-10-14	TP	Transfer of rights	Free format text: 860109 CONTINENTAL PHARMA INC. BRUXELLES

Publication	Publication Date	Title
Gillis et al.	2002	Development and validation of a biosensor-based immunoassay for progesterone in bovine milk
CN102692507B (zh)	2015-09-16	脂蛋白相关磷脂酶a2(lppla2)测定试剂盒(胶乳增强免疫比浊法)
US7002670B2 (en)	2006-02-21	Optical sensor and method for measuring concentration of a chemical constituent using its intrinsic optical absorbance
Chaiyarit et al.	2017	Defining and systematic analyses of aggregation indices to evaluate degree of calcium oxalate crystal aggregation
USH1344H (en)	1994-08-02	Portable automatic sensor for toxic gases
CN105929156A (zh)	2016-09-07	一种抗双链DNA抗体IgG的磁微粒化学发光定量测定试剂盒及制备和检测方法
Pitot et al.	1964	The automated assay of complete enzyme reaction rates: I. Methods and results
LU80437A1 (fr)	1980-05-07	Procede et dispositif pour le dosage de la malondialdehyde
CN205786321U (zh)	2016-12-07	一种在线检测海水中氨氮含量的装置
Rinderknecht et al.	1970	A new automated method for the determination of serum α-amylase
CN106124769A (zh)	2016-11-16	一种一步均相il‑6检测试剂盒及其制备和使用方法
Takenaka	1964	of Leucine Aminopeptidase in Serum (use of p-dimethylaminobenzaldehyde
Killingsworth et al.	1971	Automated immunoprecipitin technique for analysis of the third component of complement (C'3) in human serum
Zender et al.	1972	A kinetic method for analysis of creatinine using the DSA-560
Toffaletti et al.	1980	Spectrophotometric micro method for measurement of dialyzable calcium by use of cresolphthalein complexone and continuous-flow analysis.
Sterling et al.	1964	An automated determination of alkaline phosphatase utilizing p-nitrophenol phosphate
Blom et al.	1973	A turbidimetric continuous-flow system for immunochemical quantitation of blood proteins by use of a modified photometer
Schwartz et al.	1968	Utilization of automation for studies of enzyme kinetics
Reynolds	2000	[3H](+) MK801 radioligand binding assay at the N‐methyl‐D‐aspartate receptor
Keay et al.	1964	Automated determination of serum alkaline phosphatase using a modified bodansky technic
SU1456850A1 (ru)	1989-02-07	Способ определени пирокатехина
SU1252728A1 (ru)	1986-08-23	Способ диагностики гломерулонефрита у детей
Schaffert et al.	1964	Automated determination of serum glutamic oxalacetic and glutamic pyruvic transaminase
Amador et al.	1972	Automated serum calcium analyses corrected for dialysis effects
SU1573430A1 (ru)	1990-06-23	Способ определени активности ингибиторов трипсина в плазме крови