LU86004A1 - Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose - Google Patents

Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose Download PDF

Info

Publication number: LU86004A1
Authority: LU; Luxembourg
Prior art keywords: vitamin; none; oxytetracycline; composition according; hydrochloride
Prior art date: 1985-07-15

Application number

LU86004A

Other languages

English (en)

French (fr)

Inventor

Andre Speecke

Original Assignee

Ssm Int Chem Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-15

Filing date

1985-07-15

Publication date

1987-02-04

1985-07-15 Application filed by Ssm Int Chem Co Ltd filed Critical Ssm Int Chem Co Ltd

1985-07-15 Priority to LU86004A priority Critical patent/LU86004A1/fr

1986-06-24 Priority to EP86870092A priority patent/EP0214947A1/de

1986-06-25 Priority to ZA864740A priority patent/ZA864740B/xx

1986-06-27 Priority to IL79272A priority patent/IL79272A0/xx

1986-07-14 Priority to CA000513736A priority patent/CA1279013C/fr

1986-07-14 Priority to PT82982A priority patent/PT82982B/pt

1987-02-04 Publication of LU86004A1 publication Critical patent/LU86004A1/fr

Links

239000000203 mixture Substances 0.000 title claims description 26
201000008482 osteoarthritis Diseases 0.000 title claims description 10
230000000202 analgesic effect Effects 0.000 title description 3
230000003110 anti-inflammatory effect Effects 0.000 title description 2
229940088594 vitamin Drugs 0.000 claims description 21
229930003231 vitamin Natural products 0.000 claims description 21
235000013343 vitamin Nutrition 0.000 claims description 21
239000011782 vitamin Substances 0.000 claims description 21
150000003722 vitamin derivatives Chemical class 0.000 claims description 19
239000000470 constituent Substances 0.000 claims description 16
235000019156 vitamin B Nutrition 0.000 claims description 13
DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 12
AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 12
IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 claims description 12
239000011720 vitamin B Substances 0.000 claims description 12
239000004100 Oxytetracycline Substances 0.000 claims description 11
229960000625 oxytetracycline Drugs 0.000 claims description 11
IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 claims description 11
235000019366 oxytetracycline Nutrition 0.000 claims description 11
YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 10
229930003270 Vitamin B Natural products 0.000 claims description 9
AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 8
229960002477 riboflavin Drugs 0.000 claims description 8
MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 claims description 7
229960002061 ergocalciferol Drugs 0.000 claims description 7
235000001892 vitamin D2 Nutrition 0.000 claims description 7
239000011653 vitamin D2 Substances 0.000 claims description 7
MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims description 7
229960004368 oxytetracycline hydrochloride Drugs 0.000 claims description 6
JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 claims description 6
MWKJTNBSKNUMFN-UHFFFAOYSA-N trifluoromethyltrimethylsilane Chemical compound C[Si](C)(C)C(F)(F)F MWKJTNBSKNUMFN-UHFFFAOYSA-N 0.000 claims description 6
SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 5
239000003242 anti bacterial agent Substances 0.000 claims description 5
230000003115 biocidal effect Effects 0.000 claims description 5
229960002685 biotin Drugs 0.000 claims description 5
235000020958 biotin Nutrition 0.000 claims description 5
239000011616 biotin Substances 0.000 claims description 5
235000020374 simple syrup Nutrition 0.000 claims description 5
235000019157 thiamine Nutrition 0.000 claims description 5
239000011721 thiamine Substances 0.000 claims description 5
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 4
239000011703 D-panthenol Substances 0.000 claims description 4
235000004866 D-panthenol Nutrition 0.000 claims description 4
FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 4
229930003471 Vitamin B2 Natural products 0.000 claims description 4
FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 4
FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 4
229960002079 calcium pantothenate Drugs 0.000 claims description 4
RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 4
229960003949 dexpanthenol Drugs 0.000 claims description 4
CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims description 4
239000000395 magnesium oxide Substances 0.000 claims description 4
AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 claims description 4
229960003966 nicotinamide Drugs 0.000 claims description 4
235000005152 nicotinamide Nutrition 0.000 claims description 4
239000011570 nicotinamide Substances 0.000 claims description 4
LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims description 4
235000019192 riboflavin Nutrition 0.000 claims description 4
239000002151 riboflavin Substances 0.000 claims description 4
230000002195 synergetic effect Effects 0.000 claims description 4
235000019155 vitamin A Nutrition 0.000 claims description 4
239000011719 vitamin A Substances 0.000 claims description 4
235000019164 vitamin B2 Nutrition 0.000 claims description 4
239000011716 vitamin B2 Substances 0.000 claims description 4
235000019160 vitamin B3 Nutrition 0.000 claims description 4
239000011708 vitamin B3 Substances 0.000 claims description 4
229940045997 vitamin a Drugs 0.000 claims description 4
206010061218 Inflammation Diseases 0.000 claims description 3
230000004054 inflammatory process Effects 0.000 claims description 3
210000003127 knee Anatomy 0.000 claims description 3
230000005499 meniscus Effects 0.000 claims description 3
229960000344 thiamine hydrochloride Drugs 0.000 claims description 3
235000019190 thiamine hydrochloride Nutrition 0.000 claims description 3
239000011747 thiamine hydrochloride Substances 0.000 claims description 3
DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 3
208000008035 Back Pain Diseases 0.000 claims description 2
239000004322 Butylated hydroxytoluene Substances 0.000 claims description 2
NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 2
208000003618 Intervertebral Disc Displacement Diseases 0.000 claims description 2
208000008930 Low Back Pain Diseases 0.000 claims description 2
208000008765 Sciatica Diseases 0.000 claims description 2
208000010040 Sprains and Strains Diseases 0.000 claims description 2
229940095259 butylated hydroxytoluene Drugs 0.000 claims description 2
235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 2
229960002104 cyanocobalamin Drugs 0.000 claims description 2
235000000639 cyanocobalamin Nutrition 0.000 claims description 2
239000011666 cyanocobalamin Substances 0.000 claims description 2
210000003205 muscle Anatomy 0.000 claims description 2
235000008160 pyridoxine Nutrition 0.000 claims description 2
239000011677 pyridoxine Substances 0.000 claims description 2
229940011671 vitamin b6 Drugs 0.000 claims description 2
206010070817 Bone decalcification Diseases 0.000 claims 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
229960003495 thiamine Drugs 0.000 claims 1
229940046001 vitamin b complex Drugs 0.000 claims 1
235000020357 syrup Nutrition 0.000 description 5
239000006188 syrup Substances 0.000 description 5
239000002552 dosage form Substances 0.000 description 4
239000003814 drug Substances 0.000 description 4
230000003902 lesion Effects 0.000 description 4
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
229940079593 drug Drugs 0.000 description 3
239000000546 pharmaceutical excipient Substances 0.000 description 3
239000000243 solution Substances 0.000 description 3
GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
241000894006 Bacteria Species 0.000 description 2
-1 Oxytetracycline compound Chemical class 0.000 description 2
208000002193 Pain Diseases 0.000 description 2
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
241000589516 Pseudomonas Species 0.000 description 2
241000607142 Salmonella Species 0.000 description 2
229940088710 antibiotic agent Drugs 0.000 description 2
210000000988 bone and bone Anatomy 0.000 description 2
239000003246 corticosteroid Substances 0.000 description 2
230000001079 digestive effect Effects 0.000 description 2
239000003085 diluting agent Substances 0.000 description 2
201000010099 disease Diseases 0.000 description 2
201000004595 synovitis Diseases 0.000 description 2
230000001988 toxicity Effects 0.000 description 2
231100000419 toxicity Toxicity 0.000 description 2
241000186361 Actinobacteria <class> Species 0.000 description 1
208000006820 Arthralgia Diseases 0.000 description 1
241000193830 Bacillus <bacterium> Species 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
108010078777 Colistin Proteins 0.000 description 1
208000035473 Communicable disease Diseases 0.000 description 1
206010063045 Effusion Diseases 0.000 description 1
208000037147 Hypercalcaemia Diseases 0.000 description 1
206010033971 Paratyphoid fever Diseases 0.000 description 1
241000187419 Streptomyces rimosus Species 0.000 description 1
206010042674 Swelling Diseases 0.000 description 1
229930003316 Vitamin D Natural products 0.000 description 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
KIPLYOUQVMMOHB-MXWBXKMOSA-L [Ca++].CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O.CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O Chemical compound [Ca++].CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O.CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O KIPLYOUQVMMOHB-MXWBXKMOSA-L 0.000 description 1
USDJGQLNFPZEON-UHFFFAOYSA-N [[4,6-bis(hydroxymethylamino)-1,3,5-triazin-2-yl]amino]methanol Chemical compound OCNC1=NC(NCO)=NC(NCO)=N1 USDJGQLNFPZEON-UHFFFAOYSA-N 0.000 description 1
208000005298 acute pain Diseases 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
229940124599 anti-inflammatory drug Drugs 0.000 description 1
206010003246 arthritis Diseases 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
239000011575 calcium Substances 0.000 description 1
239000000969 carrier Substances 0.000 description 1
208000037976 chronic inflammation Diseases 0.000 description 1
230000006020 chronic inflammation Effects 0.000 description 1
229960001127 colistin sulfate Drugs 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
229960001334 corticosteroids Drugs 0.000 description 1
230000003412 degenerative effect Effects 0.000 description 1
208000035475 disorder Diseases 0.000 description 1
230000000694 effects Effects 0.000 description 1
208000010227 enterocolitis Diseases 0.000 description 1
230000000148 hypercalcaemia Effects 0.000 description 1
208000030915 hypercalcemia disease Diseases 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
230000002458 infectious effect Effects 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
208000014674 injury Diseases 0.000 description 1
230000000968 intestinal effect Effects 0.000 description 1
230000002427 irreversible effect Effects 0.000 description 1
210000003734 kidney Anatomy 0.000 description 1
210000000629 knee joint Anatomy 0.000 description 1
230000004807 localization Effects 0.000 description 1
238000002483 medication Methods 0.000 description 1
230000004060 metabolic process Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
ZESIAEVDVPWEKB-ORCFLVBFSA-N n-[(2s)-4-amino-1-[[(2s,3r)-1-[[(2s)-4-amino-1-oxo-1-[[(3s,6s,9s,12s,15r,18s,21s)-6,9,18-tris(2-aminoethyl)-3-[(1r)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-h Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O ZESIAEVDVPWEKB-ORCFLVBFSA-N 0.000 description 1
230000000926 neurological effect Effects 0.000 description 1
229940055726 pantothenic acid Drugs 0.000 description 1
239000011713 pantothenic acid Substances 0.000 description 1
235000019161 pantothenic acid Nutrition 0.000 description 1
229940056360 penicillin g Drugs 0.000 description 1
244000144977 poultry Species 0.000 description 1
230000035755 proliferation Effects 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
230000008961 swelling Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
239000011885 synergistic combination Substances 0.000 description 1
229940063650 terramycin Drugs 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
230000008733 trauma Effects 0.000 description 1
235000019166 vitamin D Nutrition 0.000 description 1
239000011710 vitamin D Substances 0.000 description 1
150000003710 vitamin D derivatives Chemical class 0.000 description 1
229940046008 vitamin d Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

LU86004A 1985-07-15 1985-07-15 Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose LU86004A1 (fr)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
LU86004A LU86004A1 (fr)	1985-07-15	1985-07-15	Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose
EP86870092A EP0214947A1 (de)	1985-07-15	1986-06-24	Schmerzstillende und entzündungshemmende Zusammensetzung für die Behandlung von Arthrose
ZA864740A ZA864740B (en)	1985-07-15	1986-06-25	Antalgic and antiinflammatory composition for healing arthritis
IL79272A IL79272A0 (en)	1985-07-15	1986-06-27	Oxytetracycline type antibiotic composition
CA000513736A CA1279013C (fr)	1985-07-15	1986-07-14	Composition antibiotique pour soigner l'arthrite
PT82982A PT82982B (pt)	1985-07-15	1986-07-14	Processo de producao de uma composicao antibiotica sinergica dum composto de oxitetraciclina

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
LU86004A LU86004A1 (fr)	1985-07-15	1985-07-15	Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose
LU86004		1985-07-15

Publications (1)

Publication Number	Publication Date
LU86004A1 true LU86004A1 (fr)	1987-02-04

Family

ID=19730511

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU86004A LU86004A1 (fr)	1985-07-15	1985-07-15	Composition antalgique et anti-inflammatoire destinee au traitement de l'arthrose

Country Status (5)

Country	Link
EP (1)	EP0214947A1 (de)
CA (1)	CA1279013C (de)
LU (1)	LU86004A1 (de)
PT (1)	PT82982B (de)
ZA (1)	ZA864740B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8906966B2 (en)	2006-07-13	2014-12-09	Paul Sherwood	Medicaments containing panthenol
WO2009010707A1 (en) *	2007-07-13	2009-01-22	Prototype Bioforum Limited	Injectable pharmaceutical compositions containing panthenol

1985
- 1985-07-15 LU LU86004A patent/LU86004A1/fr unknown
1986
- 1986-06-24 EP EP86870092A patent/EP0214947A1/de not_active Withdrawn
- 1986-06-25 ZA ZA864740A patent/ZA864740B/xx unknown
- 1986-07-14 PT PT82982A patent/PT82982B/pt not_active IP Right Cessation
- 1986-07-14 CA CA000513736A patent/CA1279013C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA864740B (en)	1987-02-25
PT82982A (en)	1986-08-01
PT82982B (pt)	1988-07-01
CA1279013C (fr)	1991-01-15
EP0214947A1 (de)	1987-03-18

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