LU88574I2 - CEFEPIME and its pharmaceutically acceptable salts (Maxipime R) - Google Patents

CEFEPIME and its pharmaceutically acceptable salts (Maxipime R)

Info

Publication number: LU88574I2
Authority: LU; Luxembourg
Prior art keywords: maxipime; cefepime; pharmaceutically acceptable; acceptable salts; salts
Prior art date: 1985-08-05

Application number

LU88574C

Other languages

French (fr)

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-05

Filing date

1986-08-04

Publication date

1995-03-01

1986-08-04 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1995-03-01 Publication of LU88574I2 publication Critical patent/LU88574I2/en

Links

JFPVXVDWJQMJEE-QMTHXVAHSA-N Cefuroxime Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)C(=NOC)C1=CC=CO1 JFPVXVDWJQMJEE-QMTHXVAHSA-N 0.000 title 1
HVFLCNVBZFFHBT-ZKDACBOMSA-N cefepime Chemical compound S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1C[N+]1(C)CCCC1 HVFLCNVBZFFHBT-ZKDACBOMSA-N 0.000 title 1
229960002100 cefepime Drugs 0.000 title 1
229940021422 maxipime Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Medicinal Preparation (AREA)

LU88574C 1985-08-05 1986-08-04 CEFEPIME and its pharmaceutically acceptable salts (Maxipime R) LU88574I2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US76223585A	1985-08-05	1985-08-05

Publications (1)

Publication Number	Publication Date
LU88574I2 true LU88574I2 (en)	1995-03-01

Family

ID=25064475

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LU88574C LU88574I2 (en)	1985-08-05	1986-08-04	CEFEPIME and its pharmaceutically acceptable salts (Maxipime R)
LU86540A LU86540A1 (en)	1985-08-05	1986-08-04	CEPHALOSPORIN SALTS AND INJECTABLE COMPOSITIONS

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
LU86540A LU86540A1 (en)	1985-08-05	1986-08-04	CEPHALOSPORIN SALTS AND INJECTABLE COMPOSITIONS

Country Status (34)

Country	Link
JP (1)	JPH0615548B2 (en)
KR (1)	KR930003121B1 (en)
AR (1)	AR243894A1 (en)
AT (1)	AT390957B (en)
AU (1)	AU597262B2 (en)
BE (1)	BE905219A (en)
CA (1)	CA1284994C (en)
CH (1)	CH675581A5 (en)
CS (2)	CS276717B6 (en)
CY (1)	CY1614A (en)
DD (2)	DD254941A5 (en)
DE (1)	DE3626375A1 (en)
DK (1)	DK162053C (en)
EG (1)	EG18003A (en)
ES (1)	ES2002112A6 (en)
FI (1)	FI84484C (en)
FR (1)	FR2585705B1 (en)
GB (1)	GB2179936B (en)
GR (1)	GR862055B (en)
HK (1)	HK99691A (en)
HU (1)	HU196602B (en)
IE (1)	IE59222B1 (en)
IL (1)	IL79608A (en)
IT (1)	IT1197067B (en)
LU (2)	LU88574I2 (en)
MY (1)	MY102212A (en)
NL (1)	NL8601991A (en)
OA (1)	OA08672A (en)
PT (1)	PT83134B (en)
SE (1)	SE469633B (en)
SG (1)	SG79791G (en)
SU (1)	SU1516013A3 (en)
YU (1)	YU45793B (en)
ZA (1)	ZA865842B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4883868A (en) *	1984-12-27	1989-11-28	Banyu Pharmaceutical Co., Ltd.	7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) *	1984-12-27	1990-09-25	Banyu Pharmaceutical Company, Ltd.	Crystalline cephalosporin compounds
US5244891A (en) *	1985-08-05	1993-09-14	Bristol-Myers Squibb Company	Injectable compositions of cefepime dihydrochloride hydrate
US4910301A (en) *	1985-08-05	1990-03-20	Bristol-Myers Company	Cefepime cephalosporin salts
US4808617A (en) *	1985-12-18	1989-02-28	Bristol-Myers Company	Lyophilized or precipitated cephalosporin zwitterion and salt combination
KR950010084B1 (en) *	1987-06-25	1995-09-06	반유세이야꾸 가부시끼가이샤	Crystalline Cephalosporin Compounds, Preparations thereof and Intermediates thereof
JPH02101081A (en) *	1988-10-08	1990-04-12	Meiji Seika Kaisha Ltd	Crystalline dihydrochloride of cephalosporin derivative and production thereof
CA2011116C (en) *	1989-03-06	1999-11-16	Murray A. Kaplan	Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) *	1992-09-08	1994-03-09	Elizabeth A. Garofalo	Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
ATE202109T1 (en) *	1993-03-12	2001-06-15	Upjohn Co	CRYSTALLINE CEFTIOFUR (FREE ACID)
EP0638573A1 (en) *	1993-08-10	1995-02-15	Lucky Ltd.	Crystalline hydrates of cephalosporin and process for preparation thereof
ES2298850T3 (en)	2003-12-23	2008-05-16	Sandoz Gmbh	PROCESS FOR THE PRODUCTION OF INTERMEDIATES TO USE IN THE SYNTHESIS OF CEPHALOSPORINE.
WO2008056221A2 (en) *	2006-11-06	2008-05-15	Orchid Chemicals & Pharmaceuticals Limited	Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (en) *	2012-02-29	2013-08-29	Aicuris Gmbh & Co. Kg	Pharmaceutical preparation containing an antiviral dihydroquinazoline derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151588A (en) *	1979-05-14	1980-11-26	Takeda Chem Ind Ltd	Preparation of cephalosporin salt crystal
CA1213882A (en) *	1982-03-04	1986-11-12	Jun Okumura	Cephalosporins
US4406899A (en) *	1982-03-04	1983-09-27	Bristol-Myers Company	Cephalosporins
US4525473A (en) *	1983-03-30	1985-06-25	Bristol-Myers Company	Cephalosporins
DE3419015A1 (en) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING CEPHALOSPORINES
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds
GB2165245B (en) *	1984-10-01	1988-05-25	Glaxo Group Ltd	Chemical compounds

1986
- 1986-07-28 CA CA000514766A patent/CA1284994C/en not_active Expired - Lifetime
- 1986-07-28 FR FR8610892A patent/FR2585705B1/en not_active Expired
- 1986-07-29 AR AR86304717A patent/AR243894A1/en active
- 1986-07-30 AU AU60694/86A patent/AU597262B2/en not_active Expired
- 1986-07-31 YU YU137186A patent/YU45793B/en unknown
- 1986-08-01 IE IE207886A patent/IE59222B1/en not_active IP Right Cessation
- 1986-08-01 FI FI863155A patent/FI84484C/en not_active IP Right Cessation
- 1986-08-04 JP JP61183288A patent/JPH0615548B2/en not_active Expired - Lifetime
- 1986-08-04 DE DE19863626375 patent/DE3626375A1/en not_active Ceased
- 1986-08-04 GR GR862055A patent/GR862055B/en unknown
- 1986-08-04 ZA ZA865842A patent/ZA865842B/en unknown
- 1986-08-04 SE SE8603308A patent/SE469633B/en not_active IP Right Cessation
- 1986-08-04 DK DK371886A patent/DK162053C/en not_active IP Right Cessation
- 1986-08-04 BE BE07217010A patent/BE905219A/en not_active IP Right Cessation
- 1986-08-04 LU LU88574C patent/LU88574I2/en unknown
- 1986-08-04 CS CS865827A patent/CS276717B6/en unknown
- 1986-08-04 GB GB8618989A patent/GB2179936B/en not_active Expired
- 1986-08-04 CH CH3117/86A patent/CH675581A5/de not_active IP Right Cessation
- 1986-08-04 LU LU86540A patent/LU86540A1/en unknown
- 1986-08-04 CS CS903570A patent/CS276849B6/en unknown
- 1986-08-04 SU SU864027914A patent/SU1516013A3/en active
- 1986-08-04 PT PT83134A patent/PT83134B/en unknown
- 1986-08-04 IT IT21409/86A patent/IT1197067B/en active Protection Beyond IP Right Term
- 1986-08-04 IL IL79608A patent/IL79608A/en not_active IP Right Cessation
- 1986-08-04 NL NL8601991A patent/NL8601991A/en not_active Application Discontinuation
- 1986-08-05 ES ES8600872A patent/ES2002112A6/en not_active Expired
- 1986-08-05 AT AT0211086A patent/AT390957B/en not_active IP Right Cessation
- 1986-08-05 OA OA58918A patent/OA08672A/en unknown
- 1986-08-05 DD DD86293433A patent/DD254941A5/en unknown
- 1986-08-05 HU HU863376A patent/HU196602B/en unknown
- 1986-08-05 KR KR1019860006445A patent/KR930003121B1/en not_active Expired - Lifetime
1987
- 1987-09-29 MY MYPI87002279A patent/MY102212A/en unknown
1988
- 1988-03-30 DD DD88314213A patent/DD268395A5/en unknown
1989
- 1989-08-04 EG EG489/86A patent/EG18003A/en active
1991
- 1991-10-02 SG SG797/91A patent/SG79791G/en unknown
- 1991-12-05 HK HK996/91A patent/HK99691A/en not_active IP Right Cessation
1992
- 1992-07-10 CY CY1614A patent/CY1614A/en unknown

Also Published As

Publication number	Publication date
AU6069486A (en)	1987-02-12
ATA211086A (en)	1990-01-15
CA1284994C (en)	1991-06-18
FI863155A7 (en)	1987-02-06
CS276717B6 (en)	1992-08-12
SU1516013A3 (en)	1989-10-15
CY1614A (en)	1992-07-10
SE8603308D0 (en)	1986-08-04
BE905219A (en)	1987-02-04
IL79608A (en)	1991-07-18
CH675581A5 (en)	1990-10-15
LU86540A1 (en)	1987-03-06
DK162053B (en)	1991-09-09
DD268395A5 (en)	1989-05-31
IE862078L (en)	1987-02-05
AR243894A1 (en)	1993-09-30
DE3626375A1 (en)	1987-02-12
IT1197067B (en)	1988-11-25
DK371886D0 (en)	1986-08-04
ZA865842B (en)	1987-04-29
AU597262B2 (en)	1990-05-31
FR2585705A1 (en)	1987-02-06
PT83134A (en)	1986-09-01
FI84484C (en)	1991-12-10
KR930003121B1 (en)	1993-04-19
SE8603308L (en)	1987-02-06
YU137186A (en)	1987-12-31
OA08672A (en)	1989-03-31
GB8618989D0 (en)	1986-09-17
YU45793B (en)	1992-07-20
AT390957B (en)	1990-07-25
JPH0615548B2 (en)	1994-03-02
KR880002530A (en)	1988-05-09
JPS62103090A (en)	1987-05-13
HUT41802A (en)	1987-05-28
SE469633B (en)	1993-08-09
NL8601991A (en)	1987-03-02
IL79608A0 (en)	1986-11-30
HK99691A (en)	1991-12-13
HU196602B (en)	1988-12-28
DK162053C (en)	1992-02-10
DK371886A (en)	1987-02-06
CS276849B6 (en)	1992-08-12
FI863155A0 (en)	1986-08-01
GB2179936B (en)	1989-04-26
FR2585705B1 (en)	1989-01-13
MY102212A (en)	1992-05-15
PT83134B (en)	1989-07-31
FI84484B (en)	1991-08-30
SG79791G (en)	1991-11-15
IT8621409A0 (en)	1986-08-04
GB2179936A (en)	1987-03-18
EG18003A (en)	1991-08-30
IT8621409A1 (en)	1988-02-04
DD254941A5 (en)	1988-03-16
ES2002112A6 (en)	1988-07-16
IE59222B1 (en)	1994-01-26
GR862055B (en)	1986-12-24

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DK346486D0 (en)	1986-07-21	AMINOSALICYLIC ACID DERIVATIVES AND PHARMACEUTICAL AGENTS
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DK139286A (en)	1986-10-03	INSIDE AND NAPHTHALENDER DERIVATIVES
GR862032B (en)	1986-12-24	Dopamine-b-hydroxylase inhibitors
ZW21586A1 (en)	1987-06-24	Dopamine-b-hydroxylase inhibitors
DK518085A (en)	1987-05-12	hammer mill
GB2173183B (en)	1988-12-07	Scale inhibitors
DK172486D0 (en)	1986-04-16	HETEROCYCLYL-PENEM COMPOUNDS AND THEIR PREPARATION AND USE
FI860123A7 (en)	1986-07-12	Process for the preparation of 1-2-/5-dimethylaminomethyl-2-(furylmethylthio)ethyl/amino-1-methylamino-2-nitroethylene and its hydrochloride
IT1200125B (en)	1989-01-05	Cephalosporin compounds and procedure to produce them
PT87198A (en)	1989-05-12	MILL OF HAMMERS
AT386967B (en)	1988-11-10	STORAGE OF A SWING MILL
IT1200094B (en)	1989-01-05	ISOKINOLINE DERIVATIVES AND ITS THERAPEUTICALLY ACCEPTABLE SALTS