LV15575A - Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana - Google Patents

Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Info

Publication number
LV15575A
LV15575A LVP-19-75A LV190075A LV15575A LV 15575 A LV15575 A LV 15575A LV 190075 A LV190075 A LV 190075A LV 15575 A LV15575 A LV 15575A
Authority
LV
Latvia
Prior art keywords
methods
selenophenochromenes
synthesis
same agents
deuterated analogues
Prior art date
Application number
LVP-19-75A
Other languages
English (en)
Inventor
Pāvels ARSENJANS
Original Assignee
Latvijas Organiskās Sintēzes Institūts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Latvijas Organiskās Sintēzes Institūts filed Critical Latvijas Organiskās Sintēzes Institūts
Priority to LVP-19-75A priority Critical patent/LV15575A/lv
Priority to DE112020006237.6T priority patent/DE112020006237T5/de
Priority to PCT/IB2020/056817 priority patent/WO2021123928A1/en
Priority to US17/785,205 priority patent/US12612417B2/en
Publication of LV15575A publication Critical patent/LV15575A/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Šis izgudrojums attiecas uz jauniem deiterētiem selenofēnhromēna atvasinājumiem kā pretaudzēju aģentiem, kā arī šo savienojumu sintēzes metodēm un šo savienojumu izmantošanu dažādos farmaceitiskajos sastāvos, lai ārstētu vēzi.
LVP-19-75A 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana LV15575A (lv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana
DE112020006237.6T DE112020006237T5 (de) 2019-12-20 2020-07-21 Deuterierte Analoga von Selenophenochromenen, deren Synthese und Verfahren zur Verwendung dieser Mittel
PCT/IB2020/056817 WO2021123928A1 (en) 2019-12-20 2020-07-21 Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents
US17/785,205 US12612417B2 (en) 2019-12-20 2020-07-21 Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Publications (1)

Publication Number Publication Date
LV15575A true LV15575A (lv) 2021-06-20

Family

ID=69063841

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Country Status (3)

Country Link
DE (1) DE112020006237T5 (lv)
LV (1) LV15575A (lv)
WO (1) WO2021123928A1 (lv)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS56096B1 (sr) 2011-05-18 2017-10-31 Concert Pharmaceuticals Inc Deuterisani derivati ivakaftora
US20160024084A1 (en) 2013-03-15 2016-01-28 Concert Pharmaceuticals, Inc. Deuterated palbociclib
US10561681B2 (en) 2016-07-21 2020-02-18 Latvian Institute Of Organic Synthesis Antimetastatic 2H-selenopheno[3,2-h]chromenes, synthesis thereof, and methods of using same agents
JOP20190209A1 (ar) * 2017-03-16 2019-09-12 Astrazeneca Ab مركبات إيميدازو [ 4، 5-c ] كينولين-2-أون ديوترومية واستخدامها في علاج السرطان
WO2019183403A1 (en) 2018-03-21 2019-09-26 Izumi Technology, Llc , Deuterated analogs of elacridar

Also Published As

Publication number Publication date
US20230002411A1 (en) 2023-01-05
WO2021123928A1 (en) 2021-06-24
DE112020006237T5 (de) 2022-11-03

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