LV15575A - Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana - Google Patents

Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Info

Publication number
LV15575A
LV15575A LVP-19-75A LV190075A LV15575A LV 15575 A LV15575 A LV 15575A LV 190075 A LV190075 A LV 190075A LV 15575 A LV15575 A LV 15575A
Authority
LV
Latvia
Prior art keywords
methods
selenophenochromenes
synthesis
same agents
deuterated analogues
Prior art date
Application number
LVP-19-75A
Other languages
English (en)
Inventor
Pāvels ARSENJANS
Original Assignee
Latvijas Organiskās Sintēzes Institūts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Latvijas Organiskās Sintēzes Institūts filed Critical Latvijas Organiskās Sintēzes Institūts
Priority to LVP-19-75A priority Critical patent/LV15575A/lv
Priority to US17/785,205 priority patent/US12612417B2/en
Priority to DE112020006237.6T priority patent/DE112020006237T5/de
Priority to PCT/IB2020/056817 priority patent/WO2021123928A1/en
Publication of LV15575A publication Critical patent/LV15575A/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Šis izgudrojums attiecas uz jauniem deiterētiem selenofēnhromēna atvasinājumiem kā pretaudzēju aģentiem, kā arī šo savienojumu sintēzes metodēm un šo savienojumu izmantošanu dažādos farmaceitiskajos sastāvos, lai ārstētu vēzi.
LVP-19-75A 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana LV15575A (lv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana
US17/785,205 US12612417B2 (en) 2019-12-20 2020-07-21 Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents
DE112020006237.6T DE112020006237T5 (de) 2019-12-20 2020-07-21 Deuterierte Analoga von Selenophenochromenen, deren Synthese und Verfahren zur Verwendung dieser Mittel
PCT/IB2020/056817 WO2021123928A1 (en) 2019-12-20 2020-07-21 Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Publications (1)

Publication Number Publication Date
LV15575A true LV15575A (lv) 2021-06-20

Family

ID=69063841

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-19-75A LV15575A (lv) 2019-12-20 2019-12-20 Selenofēnhromēnu deiterēti analogi, to iegūšana un izmantošana

Country Status (4)

Country Link
US (1) US12612417B2 (lv)
DE (1) DE112020006237T5 (lv)
LV (1) LV15575A (lv)
WO (1) WO2021123928A1 (lv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LV15485B (lv) * 2018-09-13 2020-06-20 Latvijas Organiskās Sintēzes Institūts Selenofēnhromenonu hidroksāmskābes, to izgatavošana un izmantošana angioģenēzes inhibīcijā

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME03652B (me) 2011-05-18 2020-07-20 Vertex Pharmaceuticals Europe Ltd Deuterisani derivati ivakaftora
JP2016512831A (ja) 2013-03-15 2016-05-09 コンサート ファーマシューティカルズ インコーポレイテッド 重水素化されたパルボシクリブ
AU2016415412B2 (en) 2016-07-21 2019-07-11 Latvian Institute Of Organic Synthesis Antimetastatic 2H-selenopheno[3,2-h]chromenes, synthesis thereof, and methods of using same agents
JOP20190209A1 (ar) 2017-03-16 2019-09-12 Astrazeneca Ab مركبات إيميدازو [ 4، 5-c ] كينولين-2-أون ديوترومية واستخدامها في علاج السرطان
JP7436375B2 (ja) 2018-03-21 2024-02-21 イズミ テクノロジー，エルエルシー エラクリダールの重水素化類似体

Also Published As

Publication number Publication date
DE112020006237T5 (de) 2022-11-03
US20230002411A1 (en) 2023-01-05
US12612417B2 (en) 2026-04-28
WO2021123928A1 (en) 2021-06-24

Similar Documents

Publication Publication Date Title
ZA202001564B (en) Anti- folate receptor alpha antibody conjugates and their uses
UA130338C2 (uk) Кон'югат ліганд-лікарський засіб аналога ексатекану, спосіб його отримання та його застосування
NZ777871A (en) Small molecule modulators of il-17
MX2018005019A (es) Derivado benzofurano, su metodo de preparacion, y sus usos en medicinas.
EP4420728A3 (en) Novel chroman derivatives having estrogen receptor degradation activity and uses thereof
MX391180B (es) Derivado de pirazolo-heteroarilo, metodo de preparacion y uso medico del mismo
TW200621777A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
GEAP201914679A (en) New aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them
TN2017000511A1 (en) New hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them.
TN2017000524A1 (en) New bicyclic derivatives, a process for their preparation and pharmaceutical compositions containing them
CR20220207A (es) Compuestos terapéuticos y métodos de uso
TW200621262A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
CR10056A (es) [(1h-indol-5-il)-heteroariloxi]-(1-aza-biciclo[3.3.1]nonanos como ligandos colinérgicos del n-achr para el tratamiento de trastornos piscóticos y neurodegenerativos
TNSN07360A1 (en) Substituted pyrrolo-pyridines, composition containing them, method for their producing and use thereof
BR112012013431A8 (pt) composto, composição farmacêutica e seu uso
BR112019001253A2 (pt) composto, composição farmacêutica, e, métodos de tratamento de câncer ou de atrofia muscular e de doença de parkinson.
MX2010002210A (es) Derivados de catecolamina y profarmacos de los mismos.
MY209035A (en) Tricyclic compounds and their use
MX2017015879A (es) Composiciones de hidroxipropil beta-ciclodextrina y metodos.
MX2018007844A (es) Derivado de benzopiperidina, metodo de preparacion del mismo y su uso medico del mismo.
GEP20247585B (en) Furoindazole derivatives
MY206745A (en) Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
GEP20166450B (en) Cyclic n,n'-diarylthioureas and n,n'-diarylureas as androgen receptor antagonists, anti-cancer agent, method for producing and using same
EA202191515A1 (ru) Фармацевтическая композиция, содержащая апиксабан
EP4477265A3 (en) Methods of treating new-onset plaque type psoriasis using il-17 antagonists