MA25761A1 - Preparations d'antibiotiques a base de quinolone a liberation retardee, et leur procede de fabrication - Google Patents

Preparations d'antibiotiques a base de quinolone a liberation retardee, et leur procede de fabrication

Info

Publication number
MA25761A1
MA25761A1 MA26979A MA26979A MA25761A1 MA 25761 A1 MA25761 A1 MA 25761A1 MA 26979 A MA26979 A MA 26979A MA 26979 A MA26979 A MA 26979A MA 25761 A1 MA25761 A1 MA 25761A1
Authority
MA
Morocco
Prior art keywords
manufacturing
delayed release
quinolone antibiotic
antibiotic preparations
preparations
Prior art date
Application number
MA26979A
Other languages
English (en)
Inventor
Venkata-Rangarao Kanikanti
Roland Rupp
Wolfgang Weber
Peter Deuringer
Jan-Olav Henk
Takaaki Nishioka
Yoshifumi Katakawa
Chika Taniguchi
Hitoshi Ichihashi
Heino Stass
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MA25761A1 publication Critical patent/MA25761A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MA26979A 2000-06-26 2002-12-26 Preparations d'antibiotiques a base de quinolone a liberation retardee, et leur procede de fabrication MA25761A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10031043A DE10031043A1 (de) 2000-06-26 2000-06-26 Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
MA25761A1 true MA25761A1 (fr) 2003-04-01

Family

ID=7646816

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26979A MA25761A1 (fr) 2000-06-26 2002-12-26 Preparations d'antibiotiques a base de quinolone a liberation retardee, et leur procede de fabrication

Country Status (40)

Country Link
US (3) US7709022B2 (fr)
EP (1) EP1296685B1 (fr)
JP (1) JP4958373B2 (fr)
KR (1) KR100939617B1 (fr)
CN (1) CN1273138C (fr)
AR (1) AR029688A1 (fr)
AT (1) ATE355062T1 (fr)
AU (1) AU2001270573A1 (fr)
BG (1) BG65914B1 (fr)
BR (1) BRPI0111911B8 (fr)
CA (1) CA2414271C (fr)
CU (1) CU23264B7 (fr)
CY (1) CY1107574T1 (fr)
CZ (1) CZ301812B6 (fr)
DE (2) DE10031043A1 (fr)
DK (1) DK1296685T3 (fr)
DO (1) DOP2001000199A (fr)
EE (1) EE04992B1 (fr)
ES (1) ES2282270T3 (fr)
GT (1) GT200100126A (fr)
HN (1) HN2001000132A (fr)
HR (1) HRP20030050B1 (fr)
HU (1) HU229806B1 (fr)
IL (2) IL153333A0 (fr)
MA (1) MA25761A1 (fr)
MX (1) MXPA02012727A (fr)
MY (1) MY140994A (fr)
NO (1) NO325415B1 (fr)
NZ (1) NZ523352A (fr)
PE (1) PE20020207A1 (fr)
PL (1) PL203710B1 (fr)
PT (1) PT1296685E (fr)
RU (1) RU2332204C2 (fr)
SI (1) SI1296685T1 (fr)
SK (1) SK287384B6 (fr)
SV (1) SV2002000505A (fr)
TW (1) TWI279232B (fr)
UA (1) UA83616C2 (fr)
WO (1) WO2002000219A1 (fr)
ZA (1) ZA200210350B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US7491768B2 (en) * 2002-06-25 2009-02-17 Woong-Sig Moon Polymer resin formulation having anti-microbial or anti-coagulability and preparation method thereof
NZ541681A (en) * 2003-02-10 2009-02-28 Bayer Healthcare Ag Treatment of bacterial diseases of the respiratory organs by locally applying ciprofloxacin and its salts
US7638138B2 (en) * 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
WO2004087243A1 (fr) 2003-03-27 2004-10-14 Bioactis Limited Applicateur de medicament en poudre pour cavite nasale
JP4884772B2 (ja) * 2003-08-04 2012-02-29 杏林製薬株式会社 経口徐放性錠剤
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
WO2006007323A2 (fr) * 2004-06-28 2006-01-19 Alza Corporation Formes posologiques pour agents pharmaceutiques exempts d'acides a taux de dissolution et/ou de solubilite bas
CA2589551A1 (fr) * 2004-12-03 2006-06-08 Dr. Reddy's Laboratories Ltd. Compositions de ciprofloxacine a liberation modifiee
ATE549016T1 (de) * 2005-04-11 2012-03-15 Abbott Lab Pharmazeutische zusammensetzungen mit verbesserten auflöseprofilen für schwerlösliche wirkstoffe
EP1880722B1 (fr) * 2006-07-19 2010-03-17 Tabuk Pharmaceutical Manufacturing Co. Préparations pharmaceutiques des Ciprofloxacin
ES2652415T3 (es) 2006-12-26 2018-02-02 Shin Nippon Biomedical Laboratories, Ltd. Preparación para aplicación transnasal
WO2009117130A2 (fr) * 2008-03-21 2009-09-24 Mylan Pharmaceuticals, Inc. Formulation à libération prolongée contenant une cire
BRPI1007945C8 (pt) 2009-02-13 2021-05-25 Romark Laboratories Lc formulação farmacêutica de liberação controlada de nitazoxanida, tizoxanida ou uma combinação dos mesmos, e, comprimido de bicamada para administração oral
EP2429495A4 (fr) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd Compositions pharmaceutiques intranasales avec pharmacocinétique améliorée
US11033624B2 (en) * 2010-06-02 2021-06-15 Novaflux Inc. Medical item for prevention and treatment of ear infection
CN102247313A (zh) * 2010-06-11 2011-11-23 北京润德康医药技术有限公司 一种以莫西沙星为活性成分的口服缓释固体制剂
WO2015168642A1 (fr) 2014-05-02 2015-11-05 Labib Mohamed E Dispositif de libération de médicament pouvant être utilisé dans des cavités corporelles muqueuses
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
JP7857044B2 (ja) * 2021-10-19 2026-05-12 ニューロセンス セラピューティックス リミテッド シプロフロキサシン及びセレコキシブを含む組成物
CN120815189A (zh) * 2025-09-18 2025-10-21 浙江奥翔药业股份有限公司 一种西他沙星包衣片的包衣液配制方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951792A (en) 1959-11-18 1960-09-06 Smith Kline French Lab Sustained release pharmaceutical tablets
FR2100858B1 (fr) 1970-07-03 1975-06-06 Daiichi Seiyaku Co
US4122157A (en) * 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
US4293539A (en) 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
FR2470599A1 (fr) 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
DE3142854A1 (de) 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4370313A (en) 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
US4369172A (en) 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4530928A (en) 1982-01-13 1985-07-23 Merck & Co., Inc. Quinoline carboxylic acid complexes with guanidinium carbonate
US4440740A (en) 1982-04-26 1984-04-03 Merck & Co., Inc. α-Keto aldehydes as enhancing agents of gastro-intestinal drug absorption
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
IT1198386B (it) 1982-07-06 1988-12-21 Lepetit Spa Un prodotto a rilascio protratto contenente il suloctidile
IL70071A (en) 1982-11-01 1987-12-31 Merrell Dow Pharma Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4639458A (en) 1985-01-22 1987-01-27 Merck & Co., Inc. Tablet and formulation
NL8500724A (nl) 1985-03-13 1986-10-01 Univ Groningen Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
FR2585246A1 (fr) 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US5188840A (en) 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4734285A (en) 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
IT1188212B (it) 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US5286754A (en) * 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
DE3601566A1 (de) * 1986-01-21 1987-07-23 Bayer Ag Pharmazeutische zubereitungen von ciprofloxacin
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
EP0265061B1 (fr) 1986-09-18 1992-01-08 London School of Pharmacy Innovations Ltd Formulation pharmaceutique
US4869908A (en) 1987-01-09 1989-09-26 K.V. Pharmaceutical Co. Fibre formulations
US4786503A (en) 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US5200193A (en) 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
DE3720757A1 (de) 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
US5472710A (en) * 1988-04-16 1995-12-05 Schwarz Pharma Ag Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
US5032406A (en) 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5085865A (en) 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
DK469989D0 (da) 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
IT1237904B (it) 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
JPH0624959A (ja) * 1991-10-04 1994-02-01 Bayer Yakuhin Kk 胃内浮遊型薬物徐放性固形製剤
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
JP2958731B2 (ja) * 1992-02-14 1999-10-06 日本特殊陶業株式会社 酸化アルミニウム基焼結体及びその製造方法
US5582837A (en) 1992-03-25 1996-12-10 Depomed, Inc. Alkyl-substituted cellulose-based sustained-release oral drug dosage forms
IT1255522B (it) 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1256393B (it) 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
JP2686215B2 (ja) 1993-04-28 1997-12-08 信越化学工業株式会社 徐放性錠剤
IT1264696B1 (it) 1993-07-09 1996-10-04 Applied Pharma Res Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata
DE4406424A1 (de) * 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5464633A (en) 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
US5900425A (en) 1995-05-02 1999-05-04 Bayer Aktiengesellschaft Pharmaceutical preparations having controlled release of active compound and processes for their preparation
CN1048628C (zh) 1995-07-06 2000-01-26 东北制药总厂 环丙沙星注射液的制备方法
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
IT1282650B1 (it) 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US5972389A (en) 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
ES2248908T7 (es) 1997-06-06 2014-11-24 Depomed, Inc. Formas de dosificación de fármacos por vía oral y retención gástrica para liberación continuada de fármacos altamente solubles
IN186245B (fr) * 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
WO1999015172A1 (fr) 1997-09-25 1999-04-01 Bayer Aktiengesellschaft Formulation medicamenteuse a liberation controlee du principe actif
PA8466701A1 (es) * 1998-01-21 2000-09-29 Pfizer Prod Inc Comprimido de mesilato de trovafloxacino
CA2343760A1 (fr) 1998-09-14 2000-03-23 Ranbaxy Laboratories Limited Systeme d'apport medicamenteux regule administre oralement pour une regulation spatiale et temporelle
NZ518739A (en) 1999-11-02 2004-12-24 Depomed Inc Pharmacological inducement of the fed mode for enhanced drug administration to the stomach
PT1251832E (pt) 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6780057B2 (en) * 2001-12-21 2004-08-24 Intel Corporation Coaxial dual pin sockets for high speed I/O applications

Also Published As

Publication number Publication date
CY1107574T1 (el) 2013-03-13
KR20030023883A (ko) 2003-03-20
IL153333A (en) 2010-05-31
BRPI0111911B1 (pt) 2015-08-25
TWI279232B (en) 2007-04-21
BRPI0111911B8 (pt) 2021-05-25
DE10031043A1 (de) 2002-02-14
CN1438889A (zh) 2003-08-27
NO20026160L (no) 2002-12-20
DK1296685T3 (da) 2007-05-07
EP1296685B1 (fr) 2007-02-28
EE200200707A (et) 2004-08-16
NZ523352A (en) 2004-08-27
DE50112123D1 (de) 2007-04-12
SI1296685T1 (sl) 2007-06-30
ES2282270T3 (es) 2007-10-16
NO20026160D0 (no) 2002-12-20
MY140994A (en) 2010-02-12
UA83616C2 (uk) 2008-08-11
HU229806B1 (en) 2014-07-28
JP2004504278A (ja) 2004-02-12
AU2001270573A1 (en) 2002-01-08
BG65914B1 (bg) 2010-05-31
HK1058479A1 (en) 2004-05-21
NO325415B1 (no) 2008-04-21
EE04992B1 (et) 2008-04-15
US7780986B2 (en) 2010-08-24
US8187632B2 (en) 2012-05-29
HUP0300953A3 (en) 2009-04-28
SV2002000505A (es) 2002-12-02
MXPA02012727A (es) 2003-05-14
GT200100126A (es) 2002-01-31
CZ301812B6 (cs) 2010-06-30
SK18212002A3 (sk) 2003-04-01
PL360632A1 (en) 2004-09-20
BG107372A (bg) 2003-09-30
US20070065509A1 (en) 2007-03-22
US20040024018A1 (en) 2004-02-05
CA2414271A1 (fr) 2002-12-23
US20070237824A1 (en) 2007-10-11
RU2332204C2 (ru) 2008-08-27
WO2002000219A1 (fr) 2002-01-03
SK287384B6 (sk) 2010-08-09
IL153333A0 (en) 2003-07-06
ZA200210350B (en) 2004-02-10
HN2001000132A (es) 2001-09-11
US7709022B2 (en) 2010-05-04
AR029688A1 (es) 2003-07-10
CN1273138C (zh) 2006-09-06
JP4958373B2 (ja) 2012-06-20
EP1296685A1 (fr) 2003-04-02
HUP0300953A2 (hu) 2003-08-28
CU23264B7 (es) 2008-03-14
BR0111911A (pt) 2003-05-13
CZ20024216A3 (cs) 2003-04-16
HRP20030050A2 (en) 2004-06-30
HRP20030050B1 (en) 2011-07-31
DOP2001000199A (es) 2002-05-15
KR100939617B1 (ko) 2010-02-01
PE20020207A1 (es) 2002-04-27
PL203710B1 (pl) 2009-11-30
CA2414271C (fr) 2005-09-27
PT1296685E (pt) 2007-05-31
ATE355062T1 (de) 2006-03-15

Similar Documents

Publication Publication Date Title
NO20026160D0 (no) Preparater med langvarig frigivelse av kinolonantibiotika og fremgangsmåterfor fremstilling derav
AU2001291032A1 (en) Rolling socks
AU2001236820A1 (en) Semiconductor structure
AUPR174800A0 (en) Semiconductor processing
EE200000438A (et) Farmatseutiliselt aktiivne morfolinool
MXPA03004925A (es) Introduccion de componentes dentro de un proceso de fabricacion a traves de recirculacion.
AU2637801A (en) Methods of forming semiconductor structures
NO20004722D0 (no) Faste, hurtigdesintegrerende cetirizin-formuleringer
AU2001234089A1 (en) Cancer remedy comprising anthranilic acid derivative as active ingredient
GB0105893D0 (en) Pharmaceutically active compounds
NO20032657L (no) Mikropartikler med forbedret frigivelsesprofil og fremgangsmåte for fremstilling av slike
IT1319686B1 (it) Procedimento di preparazione di citalopram.
GB0017822D0 (en) Pharmaceutically active compound
DK1133495T3 (da) Semihydrochlorid af 8-cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyre
WO2001074787A3 (fr) Produit pharmaceutique cristallise
AU2000243673A1 (en) Wafer stage with magnetic bearings
AU2002365112A1 (en) Deuterium-based chemiluminescent 1,2-dioxetanes
ITPD20000167A0 (it) Struttura di iniettore particolarmente per impianto di pressofusione sottovuoto.
MXPA03005933A (es) Proceso para la fabricacion de formulaciones solidas.
ATE259577T1 (de) Elektronenbeschleuniger
PT1179650E (pt) Palco aperfeicoado
FR2818174B1 (fr) Procede de fabrication d'une cage d'allumage
ITRM20000434A0 (it) Procedimento per la preparazione di 9,10-diidro-pirrolo [2,1-b] [1,3]benzotiazepine 9-ammino sostituite.
FR2782930B1 (fr) Boule de jeu, notamment pour jeu de petanque, et procede de fabrication de ladite boule
SE0000645D0 (sv) New pharmaceutically active compounds