MA27183A1 - Composes oxo-azabicycliques - Google Patents

Composes oxo-azabicycliques

Info

Publication number: MA27183A1
Authority: MA; Morocco
Prior art keywords: group; atom; description; chosen; inclusive
Prior art date: 2002-03-08

Application number

MA27842A

Other languages

English (en)

French (fr)

Inventor

Bernard Gaudilliere

Catherine Kostlan

Wen-Song Yue

Henry Jacobelli

Jack Li

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-08

Filing date

2004-08-31

Publication date

2005-01-03

2004-08-31 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2005-01-03 Publication of MA27183A1 publication Critical patent/MA27183A1/fr

Links

150000001875 compounds Chemical class 0.000 title abstract 3
102000005741 Metalloproteases Human genes 0.000 abstract 1
108010006035 Metalloproteases Proteins 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
239000002585 base Substances 0.000 abstract 1
239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
229940126534 drug product Drugs 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000011159 matrix material Substances 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004426 substituted alkynyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA27842A 2002-03-08 2004-08-31 Composes oxo-azabicycliques MA27183A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2002/003240 WO2003076416A1 (en)	2002-03-08	2002-03-08	Oxo azabicyclic compounds

Publications (1)

Publication Number	Publication Date
MA27183A1 true MA27183A1 (fr)	2005-01-03

Family

ID=27798761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA27842A MA27183A1 (fr)	2002-03-08	2004-08-31	Composes oxo-azabicycliques

Country Status (25)

Country	Link
EP (1)	EP1492775A2 (es)
JP (1)	JP2005526070A (es)
KR (1)	KR20040095270A (es)
CN (1)	CN1738806A (es)
AP (1)	AP2004003125A0 (es)
AR (1)	AR039562A1 (es)
AU (2)	AU2002249275A1 (es)
BR (1)	BR0308280A (es)
CA (1)	CA2478706A1 (es)
CO (1)	CO5601020A2 (es)
EA (1)	EA200401053A1 (es)
EC (1)	ECSP045278A (es)
IL (1)	IL163818A0 (es)
IS (1)	IS7414A (es)
MA (1)	MA27183A1 (es)
MX (1)	MXPA04008681A (es)
NO (1)	NO20044041L (es)
OA (1)	OA12782A (es)
PA (1)	PA8568501A1 (es)
PE (1)	PE20031018A1 (es)
PL (1)	PL372622A1 (es)
SV (1)	SV2003001495A (es)
TN (1)	TNSN04169A1 (es)
UY (1)	UY27700A1 (es)
WO (2)	WO2003076416A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PA8539501A1 (es)	2001-02-14	2002-09-30	Warner Lambert Co	Compuestos triazolo como inhibidores de mmp
US6962922B2 (en)	2001-10-12	2005-11-08	Warner-Lambert Company Llc	Alkynylated quinazoline compounds
US6894057B2 (en)	2002-03-08	2005-05-17	Warner-Lambert Company	Oxo-azabicyclic compounds
AU2003249539A1 (en) *	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
EP1539709A1 (en)	2002-08-13	2005-06-15	Warner-Lambert Company LLC	Azaisoquinoline derivatives as matrix metalloproteinase inhibitors
WO2004014378A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	3-isoquinolinone derivatives as matrix metalloproteinase inhiitors
WO2004014892A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Monocyclic derivatives as matrix metalloproteinase inhibitors
JP2005539020A (ja)	2002-08-13	2005-12-22	ワーナー−ランバートカンパニーリミティドライアビリティーカンパニー	マトリクスメタロプロテイナーゼ阻害物質としてのクロモン誘導体
WO2004014375A2 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Fused bicyclic metalloproteinase inhibitors
PA8578101A1 (es)	2002-08-13	2004-05-07	Warner Lambert Co	Derivados de heterobiarilo como inhibidores de metaloproteinasa de la matriz
AU2003250470A1 (en)	2002-08-13	2004-02-25	Warner-Lambert Company Llc	Pyrimidinone fused bicyclic metalloproteinase inhibitors
MXPA05001783A (es)	2002-08-13	2005-04-25	Warner Lambert Co	Derivados de pirimidina-2,4-diona como inhibidores de las metaloproteinasas de matriz.
WO2004014909A1 (en)	2002-08-13	2004-02-19	Warner-Lambert Company Llc	Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors
WO2005016926A1 (en) *	2003-08-19	2005-02-24	Warner-Lambert Company Llc	Pyrido [3,4-d] pyrimidine derivatives as matrix metalloproteinase-13 inhibitors
DE10360835A1 (de) *	2003-12-23	2005-07-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclische Imidazolverbindungen, deren Herstellung und deren Verwendung als Arzneimittel
BRPI0510305A (pt) *	2004-04-30	2007-10-02	Takeda Pharmaceutical	composto ou um sal do mesmo, pródroga ou um sal da mesma, agente farmacêutico, método de produção do composto ou um sal do mesmo, inibidor de metaloproteinase de matriz ou um sal do mesmo ou uma pródroga do mesmo, método de inibir uma metaloproteinase de matriz, e, uso de um composto ou de um sal do mesmo ou de uma pródroga do mesmo
CA2568756A1 (en) *	2004-06-15	2005-12-29	Astrazeneca Ab	Substituted quinazolones as anti-cancer agents
CN101522676A (zh)	2006-10-05	2009-09-02	Cv医药有限公司	用作硬脂酰-CoA脱氢酶抑制剂的双环含氮杂环化合物
WO2012052451A1 (en)	2010-10-18	2012-04-26	Merz Pharma Gmbh & Co. Kgaa	Metabotropic glutamate receptor modulators
CN103524431B (zh) *	2013-09-24	2016-01-13	西安交通大学	3-苄基-4-喹唑啉酮类化合物及其合成方法和应用
JO3512B1 (ar)	2014-03-26	2020-07-05	Astex Therapeutics Ltd	مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
AU2016328693B2 (en)	2015-09-23	2021-03-11	Janssen Pharmaceutica Nv	Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer
DK3353177T3 (da)	2015-09-23	2020-08-24	Janssen Pharmaceutica Nv	Tricykliske heterocykler til behandling af cancer
FR3046793B1 (fr) *	2016-01-14	2018-01-05	Les Laboratoires Servier	Nouveaux derives de phosphinanes et azaphosphinanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR9714222A (pt) *	1996-12-17	2000-04-18	Du Pont	Método para o controle de doenças de plantas
PA8539401A1 (es) *	2001-02-14	2002-10-28	Warner Lambert Co	Quinazolinas como inhibidores de mmp-13
PA8539301A1 (es) *	2001-02-14	2002-09-30	Warner Lambert Co	Inhibidores de la metaloproteinasa de la matriz

2002
- 2002-03-08 AU AU2002249275A patent/AU2002249275A1/en not_active Abandoned
- 2002-03-08 WO PCT/EP2002/003240 patent/WO2003076416A1/en not_active Ceased
2003
- 2003-03-04 SV SV2003001495A patent/SV2003001495A/es not_active Application Discontinuation
- 2003-03-06 PE PE2003000218A patent/PE20031018A1/es not_active Application Discontinuation
- 2003-03-06 EP EP03708181A patent/EP1492775A2/en not_active Withdrawn
- 2003-03-06 IL IL16381803A patent/IL163818A0/xx unknown
- 2003-03-06 AP APAP/P/2004/003125A patent/AP2004003125A0/en unknown
- 2003-03-06 KR KR10-2004-7013994A patent/KR20040095270A/ko not_active Ceased
- 2003-03-06 MX MXPA04008681A patent/MXPA04008681A/es unknown
- 2003-03-06 WO PCT/EP2003/002277 patent/WO2003076417A2/en not_active Ceased
- 2003-03-06 EA EA200401053A patent/EA200401053A1/ru unknown
- 2003-03-06 JP JP2003574636A patent/JP2005526070A/ja not_active Withdrawn
- 2003-03-06 CN CNA038048752A patent/CN1738806A/zh active Pending
- 2003-03-06 AU AU2003212307A patent/AU2003212307A1/en not_active Abandoned
- 2003-03-06 AR ARP030100749A patent/AR039562A1/es not_active Application Discontinuation
- 2003-03-06 CA CA002478706A patent/CA2478706A1/en not_active Abandoned
- 2003-03-06 UY UY27700A patent/UY27700A1/es not_active Application Discontinuation
- 2003-03-06 PL PL03372622A patent/PL372622A1/xx not_active Application Discontinuation
- 2003-03-06 PA PA20038568501A patent/PA8568501A1/es unknown
- 2003-03-06 BR BR0308280-6A patent/BR0308280A/pt not_active IP Right Cessation
- 2003-03-06 OA OA1200400234A patent/OA12782A/en unknown
2004
- 2004-08-19 IS IS7414A patent/IS7414A/is unknown
- 2004-08-25 CO CO04082792A patent/CO5601020A2/es not_active Application Discontinuation
- 2004-08-31 MA MA27842A patent/MA27183A1/fr unknown
- 2004-09-03 EC EC2004005278A patent/ECSP045278A/es unknown
- 2004-09-03 TN TNP2004000169A patent/TNSN04169A1/fr unknown
- 2004-09-24 NO NO20044041A patent/NO20044041L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2003076417A2 (en)	2003-09-18
BR0308280A (pt)	2004-12-28
EP1492775A2 (en)	2005-01-05
JP2005526070A (ja)	2005-09-02
AU2003212307A1 (en)	2003-09-22
EA200401053A1 (ru)	2005-04-28
CO5601020A2 (es)	2006-01-31
WO2003076417A3 (en)	2003-11-13
KR20040095270A (ko)	2004-11-12
MXPA04008681A (es)	2004-12-06
TNSN04169A1 (fr)	2007-03-12
PL372622A1 (en)	2005-07-25
AP2004003125A0 (en)	2004-09-30
CA2478706A1 (en)	2003-09-18
NO20044041L (no)	2004-10-07
AR039562A1 (es)	2005-02-23
IL163818A0 (en)	2005-12-18
PA8568501A1 (es)	2003-12-19
ECSP045278A (es)	2004-10-26
OA12782A (en)	2006-07-10
CN1738806A (zh)	2006-02-22
UY27700A1 (es)	2003-10-31
PE20031018A1 (es)	2004-01-09
IS7414A (is)	2004-08-19
AU2002249275A1 (en)	2003-09-22
WO2003076416A1 (en)	2003-09-18
SV2003001495A (es)	2003-11-04

Publication	Publication Date	Title
MA27183A1 (fr)	2005-01-03	Composes oxo-azabicycliques
CA2481461A1 (en)	2003-10-30	Derivatives of n-[phenyl(piperidin-2-yl) methyl] benzamide, the preparation method thereof and application of same in therapeutics
MA27439A1 (fr)	2005-07-01	Quinazolinones spirocondensees nouvelles et leur utilisation comme inhibiteurs de phosphodiesterase
MA27774A1 (fr)	2006-02-01	Inhibiteurs de phosphatidylinositol 3-kinase
CA2656716C (fr)	2014-10-14	Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
LU90011I2 (fr)	1997-03-11	Remifentanil facultativement sous la forme d'un sel d'addition d'acide pharmaceutiquement acceptable y compris le chlorhydrate de remifentanil
MA56883B1 (fr)	2025-04-30	Dérivés de 2-hydroxycycloalcane-1-carbamoyle
MA30014B1 (fr)	2008-12-01	Derives spirocycliques
MA30784B1 (fr)	2009-10-01	Derives phenyliques et utilisation de ceux-ci en tant qu'immunomodulateurs.
MA27138A1 (fr)	2005-01-03	Composes heteroaryliques condenses a substituant azabicyclique pour le traitement d'une maladie
TNSN07145A1 (fr)	2008-11-21	Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
MA27573A1 (fr)	2005-10-03	Sinomenine et derives de sinomenine, synthese et utilisation.
KR970701698A (ko)	1997-04-12	프로스타글란딘 i₂작용물질로서의 나프탈렌 유도체(naphthalene derivatives as prostaglandin i₂agonists)
CA2496040A1 (en)	2004-03-11	Derivatives of dioxan-2-alkyl carbamates, preparation method thereof and application of same in therapeutics
MXPA04003192A (es)	2004-07-27	Sales de acido succinico de 5, 7, 14-triazatetraciclo ?10.3.1.02,11.04,9? -hexadeca-2(11), 3, 5, 7, 9-pentaeno y composiciones farmacetucias de las mismas.
MA27135A1 (fr)	2005-01-03	Agents antidiabetiques oraux
MA57000B1 (fr)	2024-03-29	Dérivés d'alpha-d-galactopyranoside
MA31674B1 (fr)	2010-09-01	Dérivés de 7 -alkynyl-1,8-naphthyridones, leur préparation et leur application en thérapeutique
FR2870541A1 (fr)	2005-11-25	Derives de pyrimidines antigonistes du recepteur de la vitronectine
MA26858A1 (fr)	2004-12-20	Acides ox(adi)azolyl-hydroxamiques utiles comme inhibiteurs de procollagene c-proteinase.
MA26953A1 (fr)	2004-12-20	Derives de pipérazine pontés.
MA27887A1 (fr)	2006-05-02	Dicetopiperazines substituees et leur utilisation comme antagonistes de l'ocytocine
MA27712A1 (fr)	2006-01-02	Triazoles utiles en therapeutique
CA2489723A1 (fr)	2003-12-24	Nouveaux derives d'aryl-{4-halogeno-4-[(heteroaryl-methylamino)-methyl]-piperidin-1-yl}-methanone, leur procede de preparation et leur utilisation a titre de medicaments
CA2225780A1 (fr)	1998-06-16	Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent