MA27607A1 - Peptides cyto-modulateurs pour traiter la cystite interstitielle - Google Patents
Peptides cyto-modulateurs pour traiter la cystite interstitielleInfo
- Publication number
- MA27607A1 MA27607A1 MA28336A MA28336A MA27607A1 MA 27607 A1 MA27607 A1 MA 27607A1 MA 28336 A MA28336 A MA 28336A MA 28336 A MA28336 A MA 28336A MA 27607 A1 MA27607 A1 MA 27607A1
- Authority
- MA
- Morocco
- Prior art keywords
- interstitial cystitis
- cyto
- treatment
- methods
- modulating peptides
- Prior art date
Links
- 208000005615 Interstitial Cystitis Diseases 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 208000029162 bladder disease Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- CWWARWOPSKGELM-SARDKLJWSA-N methyl (2s)-2-[[(2s)-2-[[2-[[(2s)-2-[[(2s)-2-[[(2s)-5-amino-2-[[(2s)-5-amino-2-[[(2s)-1-[(2s)-6-amino-2-[[(2s)-1-[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5 Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)OC)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 CWWARWOPSKGELM-SARDKLJWSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Les méthodes et compositions concernent le traitement de troubles de la vessie, en particulier, les méthodes fournissent un traitement contre la cystite interstitielle et les troubles y relatifs. Les méthodes comprennent en outre le traitement pour affecter plusieurs manifestations associées à la cystite interstitielle, y compris, la réduction de la libération d'histamine, la modulation de l'expression de la Substance P, la modulation de l'expression du facteur de croissance des neurones, la modulation des niveaux de plusieurs cytokines, et le maintien de l'intégrité de la barrière urine/sang.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42668402P | 2002-11-15 | 2002-11-15 | |
| US47083903P | 2003-05-15 | 2003-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27607A1 true MA27607A1 (fr) | 2005-11-01 |
Family
ID=32329122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28336A MA27607A1 (fr) | 2002-11-15 | 2005-06-14 | Peptides cyto-modulateurs pour traiter la cystite interstitielle |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7671026B2 (fr) |
| EP (1) | EP1594519A4 (fr) |
| JP (1) | JP2006516546A (fr) |
| KR (1) | KR20050086676A (fr) |
| AU (1) | AU2003294357A1 (fr) |
| BR (1) | BR0316290A (fr) |
| CA (1) | CA2505922A1 (fr) |
| CO (1) | CO5640064A2 (fr) |
| MA (1) | MA27607A1 (fr) |
| MX (1) | MXPA05005101A (fr) |
| NO (1) | NO20052814L (fr) |
| RU (1) | RU2005118425A (fr) |
| WO (1) | WO2004045554A2 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100055113A1 (en) * | 2006-07-27 | 2010-03-04 | The University Of Maryland, Baltimore | Cellular receptor for antiproliferative factor |
| KR101863136B1 (ko) * | 2008-01-24 | 2018-05-31 | 에스퍼란스 파마슈티컬스, 인코포레이티드 | 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법 |
| EP2328603A4 (fr) | 2008-08-18 | 2013-01-02 | Univ Maryland | Dérivés d'apf et méthodes d'utilisation afférentes |
| WO2012048721A1 (fr) | 2010-10-14 | 2012-04-19 | Xigen S.A. | Utilisation d'inhibiteurs peptidiques, aptes à pénétrer dans les cellules, de la voie de transduction du signal jnk pour le traitement de maladies oculaires inflammatoires chroniques ou non-chroniques |
| US20160304617A1 (en) | 2013-06-17 | 2016-10-20 | Asana Biosciences, Llc | 5t4-targeted immunofusion molecule and methods |
| WO2014206426A1 (fr) * | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | Nouvelle utilisation des molécules inhibitrices de la jnk pour le traitement de diverses maladies |
| WO2014206427A1 (fr) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | Nouvelle utilisation d'inhibiteurs de peptides à perméabilité cellulaire dans la voie de transduction du signal jnk pour le traitement de diverses maladies |
| WO2015197097A1 (fr) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | Nouvelle utilisation pour des molécules inhibitrices de la jnk, pour le traitement de diverses maladies |
| AU2015281361A1 (en) * | 2014-06-26 | 2016-11-17 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases |
| US10859579B2 (en) * | 2016-03-31 | 2020-12-08 | William Beaumont Hospital | Methods for detecting, diagnosing and treating ulcerative interstitial cystitis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1216900C (zh) * | 1997-04-11 | 2005-08-31 | 桑斯塔特医学有限公司 | 用于调节免疫系统活性和抑制炎症的细胞调节性亲脂肽 |
| US6696545B1 (en) * | 1997-04-11 | 2004-02-24 | Sangstat Medical Corporation | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
| US6232289B1 (en) * | 1998-04-17 | 2001-05-15 | University Of Maryland, Baltimore | Method of treating interstitial cytitis with recombinant heparin-binding epidermal growth factor-like growth factor (HB-EGF) |
| EP1542768A1 (fr) * | 2002-09-20 | 2005-06-22 | Alcon, Inc. | Utilisation d'inhibiteurs de la synthese des cytokines dans le traitement des troubles associes a la keratoconjonctivite seche |
-
2003
- 2003-11-17 JP JP2004570638A patent/JP2006516546A/ja active Pending
- 2003-11-17 US US10/535,167 patent/US7671026B2/en not_active Expired - Fee Related
- 2003-11-17 MX MXPA05005101A patent/MXPA05005101A/es not_active Application Discontinuation
- 2003-11-17 AU AU2003294357A patent/AU2003294357A1/en not_active Abandoned
- 2003-11-17 RU RU2005118425/14A patent/RU2005118425A/ru not_active Application Discontinuation
- 2003-11-17 EP EP03789840A patent/EP1594519A4/fr not_active Ceased
- 2003-11-17 KR KR1020057008774A patent/KR20050086676A/ko not_active Withdrawn
- 2003-11-17 CA CA002505922A patent/CA2505922A1/fr not_active Abandoned
- 2003-11-17 BR BR0316290-7A patent/BR0316290A/pt not_active Application Discontinuation
- 2003-11-17 WO PCT/US2003/037043 patent/WO2004045554A2/fr not_active Ceased
-
2005
- 2005-06-10 NO NO20052814A patent/NO20052814L/no unknown
- 2005-06-14 MA MA28336A patent/MA27607A1/fr unknown
- 2005-06-14 CO CO05057644A patent/CO5640064A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2005118425A (ru) | 2006-02-10 |
| EP1594519A2 (fr) | 2005-11-16 |
| MXPA05005101A (es) | 2005-09-08 |
| CO5640064A2 (es) | 2006-05-31 |
| WO2004045554A2 (fr) | 2004-06-03 |
| KR20050086676A (ko) | 2005-08-30 |
| CA2505922A1 (fr) | 2004-06-03 |
| WO2004045554A3 (fr) | 2005-07-07 |
| AU2003294357A1 (en) | 2004-06-15 |
| NO20052814D0 (no) | 2005-06-10 |
| JP2006516546A (ja) | 2006-07-06 |
| NO20052814L (no) | 2005-08-04 |
| US7671026B2 (en) | 2010-03-02 |
| BR0316290A (pt) | 2005-10-11 |
| EP1594519A4 (fr) | 2006-08-16 |
| US20060194738A1 (en) | 2006-08-31 |
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