MA27879A1 - Derives de tetrahydrocarbazole et leur utilisation pharmaceutique - Google Patents

Derives de tetrahydrocarbazole et leur utilisation pharmaceutique

Info

Publication number
MA27879A1
MA27879A1 MA28645A MA28645A MA27879A1 MA 27879 A1 MA27879 A1 MA 27879A1 MA 28645 A MA28645 A MA 28645A MA 28645 A MA28645 A MA 28645A MA 27879 A1 MA27879 A1 MA 27879A1
Authority
MA
Morocco
Prior art keywords
pharmaceutical use
tetrahydrocarbazole derivatives
tetrahydrocarbazole
derivatives
pharmaceutical
Prior art date
Application number
MA28645A
Other languages
English (en)
Inventor
Sharon Davis Boggs
Kristjan Gudmundsson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MA27879A1 publication Critical patent/MA27879A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA28645A 2003-06-12 2005-12-09 Derives de tetrahydrocarbazole et leur utilisation pharmaceutique MA27879A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47797203P 2003-06-12 2003-06-12
US49778703P 2003-08-26 2003-08-26

Publications (1)

Publication Number Publication Date
MA27879A1 true MA27879A1 (fr) 2006-05-02

Family

ID=34068099

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28645A MA27879A1 (fr) 2003-06-12 2005-12-09 Derives de tetrahydrocarbazole et leur utilisation pharmaceutique

Country Status (15)

Country Link
US (1) US7419997B2 (fr)
EP (1) EP1646610B1 (fr)
JP (1) JP2007500750A (fr)
KR (1) KR20060017544A (fr)
AU (1) AU2004256052A1 (fr)
BR (1) BRPI0411245A (fr)
CA (1) CA2528336A1 (fr)
CO (1) CO5660264A2 (fr)
DE (1) DE602004022169D1 (fr)
ES (1) ES2327416T3 (fr)
IL (1) IL172087A0 (fr)
MA (1) MA27879A1 (fr)
NO (1) NO20055750L (fr)
RU (1) RU2005138126A (fr)
WO (1) WO2005005386A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509057A (ja) * 2003-10-15 2007-04-12 カイロン コーポレイション ウイルス阻害のための組成物および方法
US7767689B2 (en) 2004-03-15 2010-08-03 Ptc Therapeutics, Inc. Carboline derivatives useful in the treatment of cancer
UA92317C2 (ru) 2004-03-15 2010-10-25 Пи-Ти-Си ТЕРАПЬЮТИКС, ИНК. Производные карболина, пригодные для ингибирования развития кровеносных сосудов
US8076352B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Administration of carboline derivatives useful in the treatment of cancer and other diseases
US8076353B2 (en) 2004-03-15 2011-12-13 Ptc Therapeutics, Inc. Inhibition of VEGF translation
WO2006012310A2 (fr) * 2004-06-25 2006-02-02 Genzyme Corporation Derives de carbazole pour le traitement de la polykystose renale
EP1819671A2 (fr) * 2004-11-22 2007-08-22 SmithKline Beecham Corporation Inhibiteurs du virus de l'hepatite c de structure carbazole
WO2006058088A2 (fr) * 2004-11-23 2006-06-01 Ptc Therapeutics, Inc. Derives de carbazole, de carboline et d'indole utilises dans l'inhibition de la production de vegf
WO2019005841A1 (fr) * 2017-06-26 2019-01-03 Rutgers, The State University Of New Jersey Composés thérapeutiques et méthodes pour traiter une infection
US10882821B1 (en) 2017-09-26 2021-01-05 The Board Of Trustees Of The Leland Stanford Junior University Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes
EP4725481A1 (fr) * 2024-10-10 2026-04-15 Leibniz-Institut für Virologie Dérivés de 1,2,3,4-tétrahydrocarbazole pour leur utilisation dans le traitement d'une infection adénovirale

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008108D0 (en) * 1990-04-10 1990-06-06 Bayer Ag Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
GB0015904D0 (en) 2000-06-28 2000-08-23 Hoffmann La Roche Inhibitors of HPV E1 helicase enzyme
DE10164564B4 (de) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)

Also Published As

Publication number Publication date
EP1646610B1 (fr) 2009-07-22
CA2528336A1 (fr) 2005-01-20
NO20055750D0 (no) 2005-12-05
EP1646610A1 (fr) 2006-04-19
RU2005138126A (ru) 2006-07-27
DE602004022169D1 (de) 2009-09-03
US20060148857A1 (en) 2006-07-06
ES2327416T3 (es) 2009-10-29
CO5660264A2 (es) 2006-07-31
IL172087A0 (en) 2009-02-11
KR20060017544A (ko) 2006-02-23
US7419997B2 (en) 2008-09-02
AU2004256052A1 (en) 2005-01-20
JP2007500750A (ja) 2007-01-18
NO20055750L (no) 2006-01-06
BRPI0411245A (pt) 2006-07-18
WO2005005386A1 (fr) 2005-01-20

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