MA28151A1 - Derives de pyrazolyle et d'imidazolyle bicycliques et leurs utilisations - Google Patents

Derives de pyrazolyle et d'imidazolyle bicycliques et leurs utilisations

Info

Publication number
MA28151A1
MA28151A1 MA29005A MA29005A MA28151A1 MA 28151 A1 MA28151 A1 MA 28151A1 MA 29005 A MA29005 A MA 29005A MA 29005 A MA29005 A MA 29005A MA 28151 A1 MA28151 A1 MA 28151A1
Authority
MA
Morocco
Prior art keywords
imidazolyl derivatives
bicyclic pyrazolyl
pyrazolyl
bicyclic
imidazolyl
Prior art date
Application number
MA29005A
Other languages
English (en)
Inventor
Philip Albert Carpino
Robert Lee Dow
David Andrew Griffith
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA28151A1 publication Critical patent/MA28151A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Dérivés de pyrazolyle et d¿imidazolyle bicycliques et leurs utilisations Des composés de formule (I) sont décrits dans le présent mémoire. Les composés se sont révélés jouer le rôle de ligands des récepteurs de cannabinoïdes et sont donc utiles dans le traitement de maladies liées à la médiation des récepteurs de cannabinoïdes chez des animaux.
MA29005A 2003-11-07 2006-05-05 Derives de pyrazolyle et d'imidazolyle bicycliques et leurs utilisations MA28151A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51828003P 2003-11-07 2003-11-07

Publications (1)

Publication Number Publication Date
MA28151A1 true MA28151A1 (fr) 2006-09-01

Family

ID=34572986

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29005A MA28151A1 (fr) 2003-11-07 2006-05-05 Derives de pyrazolyle et d'imidazolyle bicycliques et leurs utilisations

Country Status (29)

Country Link
US (2) US7151097B2 (fr)
EP (1) EP1682554A1 (fr)
JP (2) JP4056549B2 (fr)
KR (1) KR20060086396A (fr)
CN (1) CN1886407A (fr)
AP (1) AP2006003601A0 (fr)
AR (1) AR046831A1 (fr)
AU (1) AU2004286909A1 (fr)
BR (1) BRPI0416299A (fr)
CA (1) CA2544752A1 (fr)
CR (1) CR8387A (fr)
DO (1) DOP2004001024A (fr)
EA (1) EA009742B1 (fr)
EC (1) ECSP066549A (fr)
GT (1) GT200400226A (fr)
HR (1) HRP20060166A2 (fr)
IL (1) IL175283A0 (fr)
IS (1) IS8426A (fr)
MA (1) MA28151A1 (fr)
MX (1) MXPA06005023A (fr)
NL (1) NL1027434C2 (fr)
NO (1) NO20062618L (fr)
OA (1) OA13280A (fr)
PA (1) PA8616801A1 (fr)
PE (1) PE20050576A1 (fr)
TN (1) TNSN06129A1 (fr)
TW (2) TWI280245B (fr)
WO (1) WO2005044822A1 (fr)
ZA (1) ZA200603594B (fr)

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DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
US7094572B2 (en) * 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
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ITMI20041032A1 (it) * 2004-05-24 2004-08-24 Neuroscienze S C A R L Compositi farmaceutici
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
EP1797041A2 (fr) * 2004-09-27 2007-06-20 Pfizer Products Inc. Procede permettant de preparer des composes de pyrazolyle bicycliques
PA8660701A1 (es) 2005-02-04 2006-09-22 Pfizer Prod Inc Agonistas de pyy y sus usos
CA2605479A1 (fr) * 2005-04-20 2006-10-26 Pfizer Products Inc. Composes acylaminobicycliques comportant un heteroatome et leurs utilisations
JP2008542255A (ja) * 2005-05-27 2008-11-27 ファイザー・プロダクツ・インク 肥満症の治療または体重減量の維持のためのカンナビノイド−１受容体アンタゴニストおよびミクロソームトリグリセリド輸送タンパク質阻害物質の併用
US8378117B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
US7825151B2 (en) * 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
US8378096B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
WO2007046550A1 (fr) * 2005-10-21 2007-04-26 Mitsubishi Tanabe Pharma Corporation Composes pyrazole presentant une activite antagoniste du recepteur cannabinoide (cb1)
WO2007060525A2 (fr) 2005-11-28 2007-05-31 Pfizer Products Inc. Procédé de synthèse de composés bicycliques de type pyrazolyle et imidazolyle
AP2008004602A0 (en) * 2006-02-23 2008-10-31 Pfizer Ltd Melanocortin type 4 receptor agonist piperidinoylpyrrolidines
EP2727585A1 (fr) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited Méthode de dépistage in-vivo
WO2008048648A2 (fr) * 2006-10-17 2008-04-24 Acadia Pharmaceuticals Inc. Composés modulant cb1 et utilisation de ces derniers
CA2669311C (fr) 2006-11-13 2011-09-20 Pfizer Products Inc. Derives diaryle, dipyridinyle et aryl-pyridinyle et leurs utilisations
US20090062253A1 (en) * 2007-08-31 2009-03-05 Kalypsys, Inc. Heterocyclodiazepine cannabinoid receptor modulators for treatment of disease
SG176464A1 (en) 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
CA2731897C (fr) * 2008-08-06 2013-07-02 Pfizer Limited Composes diazepines et diazocanes en tant qu'agonistes de mc4
US9549006B2 (en) * 2013-07-31 2017-01-17 Cisco Technology, Inc. Self-adaptive sample period for content sharing in communication sessions
EA201991770A1 (ru) * 2013-11-08 2019-12-30 Инсайт Холдингс Корпорейшн Способ синтеза ингибитора индоламин-2,3-диоксигеназы
US11504416B2 (en) 2018-09-04 2022-11-22 Paw Power, Inc. Formulation with cannabinoids
WO2020060761A2 (fr) 2018-09-04 2020-03-26 Skodda Anja Formulation d'aliment pour animaux de compagnie contenant des cannabinoïdes
MY206471A (en) * 2019-08-09 2024-12-18 Nihon Nohyaku Co Ltd Oxazepinone derivative, agricultural/horticultural insecticide containing the same, and method for using the same

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AU2002331766A1 (en) 2001-08-31 2003-03-18 University Of Connecticut Novel pyrazole analogs acting on cannabinoid receptors
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US20040259887A1 (en) 2003-06-18 2004-12-23 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US20050026983A1 (en) 2003-07-30 2005-02-03 Pfizer Inc Imidazole compounds and uses thereof
US7151097B2 (en) * 2003-11-07 2006-12-19 Pfizer Inc. Bicyclic pyrazolyl and imidazolyl compounds and uses thereof
EP1797041A2 (fr) * 2004-09-27 2007-06-20 Pfizer Products Inc. Procede permettant de preparer des composes de pyrazolyle bicycliques

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US20070027133A1 (en) 2007-02-01
TNSN06129A1 (fr) 2007-11-15
NO20062618L (no) 2006-08-07
GT200400226A (es) 2005-09-06
JP4056549B2 (ja) 2008-03-05
US7151097B2 (en) 2006-12-19
EA200600647A1 (ru) 2006-10-27
OA13280A (en) 2007-01-31
JP2007510707A (ja) 2007-04-26
IL175283A0 (en) 2006-09-05
US20050101592A1 (en) 2005-05-12
EP1682554A1 (fr) 2006-07-26
DOP2004001024A (es) 2005-05-14
NL1027434A1 (nl) 2005-05-10
JP2007302685A (ja) 2007-11-22
AU2004286909A1 (en) 2005-05-19
TW200716135A (en) 2007-05-01
WO2005044822A1 (fr) 2005-05-19
MXPA06005023A (es) 2006-07-06
ZA200603594B (en) 2007-09-26
NL1027434C2 (nl) 2007-11-27
CR8387A (es) 2007-05-30
HRP20060166A2 (en) 2006-10-31
BRPI0416299A (pt) 2007-01-23
AR046831A1 (es) 2005-12-28
AP2006003601A0 (en) 2006-04-30
EA009742B1 (ru) 2008-04-28
TW200526669A (en) 2005-08-16
ECSP066549A (es) 2006-10-17
PE20050576A1 (es) 2005-09-14
PA8616801A1 (es) 2006-05-16
CN1886407A (zh) 2006-12-27
KR20060086396A (ko) 2006-07-31
IS8426A (is) 2006-04-21
TWI280245B (en) 2007-05-01
CA2544752A1 (fr) 2005-05-19

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