MA28337A1 - Derives de l'acide 7-phenylamino-4-quinolone-3-carboxylique, methodes pour leur production et leur utilisation en tant que medicaments - Google Patents

Derives de l'acide 7-phenylamino-4-quinolone-3-carboxylique, methodes pour leur production et leur utilisation en tant que medicaments

Info

Publication number: MA28337A1
Authority: MA; Morocco
Prior art keywords: quinolone; phenylamino; medicaments; production; methods
Prior art date: 2004-01-31

Application number

MA29216A

Other languages

English (en)

Inventor

Elisabeth Defossa

Dieter Kadereit

Sven Ruf

Thomas Klabunde

Dieter Schmoll

Andreas Herling

Karl-Ulrich Wendt

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-31

Filing date

2006-07-28

Publication date

2006-12-01

2004-01-31 Priority claimed from DE102004004973A external-priority patent/DE102004004973A1/de

2004-07-10 Priority claimed from DE102004033405A external-priority patent/DE102004033405A1/de

2006-07-28 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2006-12-01 Publication of MA28337A1 publication Critical patent/MA28337A1/fr

Links

UANVNDSRTZUBNX-UHFFFAOYSA-N 7-anilino-4-oxo-3h-quinoline-3-carboxylic acid Chemical class C=1C=C2C(=O)C(C(=O)O)C=NC2=CC=1NC1=CC=CC=C1 UANVNDSRTZUBNX-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/60—Quinoline or hydrogenated quinoline ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

MA29216A 2004-01-31 2006-07-28 Derives de l'acide 7-phenylamino-4-quinolone-3-carboxylique, methodes pour leur production et leur utilisation en tant que medicaments MA28337A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102004004973A DE102004004973A1 (de)	2004-01-31	2004-01-31	7-Phenylamino-4-chinolon-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102004033405A DE102004033405A1 (de)	2004-07-10	2004-07-10	7-Phenylamino-4-chinolon-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number	Publication Date
MA28337A1 true MA28337A1 (fr)	2006-12-01

Family

ID=34828328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA29216A MA28337A1 (fr)	2004-01-31	2006-07-28	Derives de l'acide 7-phenylamino-4-quinolone-3-carboxylique, methodes pour leur production et leur utilisation en tant que medicaments

Country Status (19)

Country	Link
EP (1)	EP1713803B1 (fr)
JP (1)	JP2007519648A (fr)
KR (1)	KR20060132671A (fr)
AR (1)	AR047516A1 (fr)
AT (1)	ATE438645T1 (fr)
AU (1)	AU2005209365A1 (fr)
BR (1)	BRPI0507309A (fr)
CA (1)	CA2554522A1 (fr)
DE (1)	DE502005007840D1 (fr)
EC (1)	ECSP066734A (fr)
IL (1)	IL176913A0 (fr)
MA (1)	MA28337A1 (fr)
OA (1)	OA13364A (fr)
PA (1)	PA8622401A1 (fr)
PE (1)	PE20051094A1 (fr)
RU (1)	RU2006131306A (fr)
TW (1)	TW200533353A (fr)
UY (1)	UY28732A1 (fr)
WO (1)	WO2005073229A1 (fr)

Families Citing this family (31)

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CN101300248A (zh) *	2005-04-21	2008-11-05	塔甘塔治疗公司	膦酸酯化的氟喹诺酮、其抗菌类似物以及预防和治疗骨和关节感染的方法
NZ566877A (en)	2005-09-29	2010-05-28	Sanofi Aventis	Phenyl-1,2,4-oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals
PE20080251A1 (es)	2006-05-04	2008-04-25	Boehringer Ingelheim Int	Usos de inhibidores de dpp iv
JP2010500300A (ja)	2006-08-08	2010-01-07	サノフィ−アベンティス	アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
US10954231B2 (en)	2006-10-16	2021-03-23	Bionomics Limited	Anxiolytic compounds
SI2074123T1 (sl)	2006-10-16	2013-03-29	Bionomics Limited	Nove anksiolitične spojine
DE102007005045B4 (de)	2007-01-26	2008-12-18	Sanofi-Aventis	Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2025674A1 (fr)	2007-08-15	2009-02-18	sanofi-aventis	Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
WO2010003624A2 (fr)	2008-07-09	2010-01-14	Sanofi-Aventis	Composés hétérocycliques, leurs procédés de préparation, médicaments comprenant lesdits composés et leur utilisation
WO2010073078A2 (fr) *	2008-12-22	2010-07-01	Orchid Research Laboratories Ltd.	Composés hétérocycliques comme inhibiteurs de hdac
WO2011107494A1 (fr)	2010-03-03	2011-09-09	Sanofi	Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
EP2582709B1 (fr)	2010-06-18	2018-01-24	Sanofi	Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2012116415A1 (fr)	2011-03-02	2012-09-07	Bionomics Limited	Nouvelles petites molécules en tant que produits thérapeutiques
WO2012120055A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683704B1 (fr)	2011-03-08	2014-12-17	Sanofi	Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
US8846666B2 (en)	2011-03-08	2014-09-30	Sanofi	Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2766349B1 (fr)	2011-03-08	2016-06-01	Sanofi	Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
WO2012120056A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120054A1 (fr)	2011-03-08	2012-09-13	Sanofi	Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683703B1 (fr)	2011-03-08	2015-05-27	Sanofi	Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation
EP2683698B1 (fr)	2011-03-08	2017-10-04	Sanofi	Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation
US8809324B2 (en)	2011-03-08	2014-08-19	Sanofi	Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
CN103649086A (zh)	2011-05-12	2014-03-19	生态学有限公司	制备萘啶的方法
EP2567959B1 (fr)	2011-09-12	2014-04-16	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
WO2013037390A1 (fr)	2011-09-12	2013-03-21	Sanofi	Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr)	2011-09-27	2015-10-21	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
BR112021002207A2 (pt)	2018-08-10	2021-05-04	Diapin Therapeutics, Llc	tri-peptídeos e tratamento de distúrbios metabólicos, cardiovasculares e inflamatórios

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Publication number	Priority date	Publication date	Assignee	Title
GB0205165D0 (en) *	2002-03-06	2002-04-17	Astrazeneca Ab	Chemical compounds

2005
- 2005-01-15 JP JP2006549988A patent/JP2007519648A/ja not_active Abandoned
- 2005-01-15 BR BRPI0507309-0A patent/BRPI0507309A/pt not_active Application Discontinuation
- 2005-01-15 DE DE502005007840T patent/DE502005007840D1/de not_active Expired - Lifetime
- 2005-01-15 KR KR1020067015355A patent/KR20060132671A/ko not_active Withdrawn
- 2005-01-15 AU AU2005209365A patent/AU2005209365A1/en not_active Abandoned
- 2005-01-15 RU RU2006131306/04A patent/RU2006131306A/ru unknown
- 2005-01-15 WO PCT/EP2005/000363 patent/WO2005073229A1/fr not_active Ceased
- 2005-01-15 OA OA1200600243A patent/OA13364A/en unknown
- 2005-01-15 CA CA002554522A patent/CA2554522A1/fr not_active Abandoned
- 2005-01-15 EP EP05700953A patent/EP1713803B1/fr not_active Expired - Lifetime
- 2005-01-15 AT AT05700953T patent/ATE438645T1/de not_active IP Right Cessation
- 2005-01-27 TW TW094102386A patent/TW200533353A/zh unknown
- 2005-01-28 AR ARP050100321A patent/AR047516A1/es unknown
- 2005-01-28 PE PE2005000109A patent/PE20051094A1/es not_active Application Discontinuation
- 2005-01-31 UY UY28732A patent/UY28732A1/es unknown
- 2005-01-31 PA PA20058622401A patent/PA8622401A1/es unknown
2006
- 2006-07-17 IL IL176913A patent/IL176913A0/en unknown
- 2006-07-28 EC EC2006006734A patent/ECSP066734A/es unknown
- 2006-07-28 MA MA29216A patent/MA28337A1/fr unknown

Also Published As

Publication number	Publication date
TW200533353A (en)	2005-10-16
DE502005007840D1 (de)	2009-09-17
EP1713803A1 (fr)	2006-10-25
WO2005073229A1 (fr)	2005-08-11
KR20060132671A (ko)	2006-12-21
EP1713803B1 (fr)	2009-08-05
ATE438645T1 (de)	2009-08-15
AR047516A1 (es)	2006-01-25
AU2005209365A1 (en)	2005-08-11
OA13364A (en)	2007-04-13
IL176913A0 (en)	2006-12-10
PE20051094A1 (es)	2006-02-07
JP2007519648A (ja)	2007-07-19
CA2554522A1 (fr)	2005-08-11
PA8622401A1 (es)	2005-08-10
ECSP066734A (es)	2006-10-31
BRPI0507309A (pt)	2007-06-26
RU2006131306A (ru)	2008-03-10
UY28732A1 (es)	2005-08-31

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DE502005000428D1 (de)	2007-04-19	Verfahren zur Herstellung von 1,2-Diaminocyclohexan-Platin(II)-Komplexen
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