MA29244B1 - Compositions permettant d'immuniser contre une mycobacterie - Google Patents

Compositions permettant d'immuniser contre une mycobacterie

Info

Publication number
MA29244B1
MA29244B1 MA30124A MA30124A MA29244B1 MA 29244 B1 MA29244 B1 MA 29244B1 MA 30124 A MA30124 A MA 30124A MA 30124 A MA30124 A MA 30124A MA 29244 B1 MA29244 B1 MA 29244B1
Authority
MA
Morocco
Prior art keywords
antigen
compositions
immunizing against
vector expressing
against mycobacteria
Prior art date
Application number
MA30124A
Other languages
English (en)
Inventor
Helen Mcshane
Ansar A Pathan
Adrian Hill
Sarah C Gilbert
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0500102.9A external-priority patent/GB0500102D0/en
Application filed by Isis Innovation filed Critical Isis Innovation
Publication of MA29244B1 publication Critical patent/MA29244B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE UNE MÉTHODE PERMETTANT DE GÉNÉRER UNE RÉPONSE IMMUNITAIRE DES LYMPHOCYTES T CHEZ UN HÔTE. CETTE MÉTHODE CONSISTE À ADMINISTRER UN VACCIN VECTORISÉ QUI COMPREND UN VECTEUR VIRAL NON RÉPLIQUANT OU À RÉPLICATION ALTÉRÉE EXPRIMANT LE PRODUIT DE TRADUCTION D'UN GÈNE 85A DE L'ANTIGÈNE MYCOBACTÉRIEN. L'INVENTION CONCERNE ÉGALEMENT DES VACCINS VECTORISÉS ET LEURS UTILISATIONS. L'INVENTION CONCERNE ENFIN UNE MÉTHODE PERMETTANT D'INDUIRE UNE RÉPONSE DES LYMPHOCYTES T MÉMOIRE CD8 ET CD4 CONTRE UN ANTIGÈNE AU MOYEN D'UN VECTEUR EXPRIMANT UN ANTIGÈNE OU UN FRAGMENT IMMUNOGÈNE DE CE DERNIER.
MA30124A 2005-01-05 2007-08-03 Compositions permettant d'immuniser contre une mycobacterie MA29244B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0500102.9A GB0500102D0 (en) 2005-01-05 2005-01-05 Method for generating a memory t cell response
US64980405P 2005-02-03 2005-02-03

Publications (1)

Publication Number Publication Date
MA29244B1 true MA29244B1 (fr) 2008-02-01

Family

ID=36062509

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30124A MA29244B1 (fr) 2005-01-05 2007-08-03 Compositions permettant d'immuniser contre une mycobacterie

Country Status (16)

Country Link
EP (1) EP1833507B1 (fr)
JP (2) JP2008526823A (fr)
KR (1) KR20070108518A (fr)
AP (1) AP2007004059A0 (fr)
AU (1) AU2006204382B2 (fr)
BR (1) BRPI0606165A2 (fr)
CA (1) CA2592756A1 (fr)
CY (1) CY1111549T1 (fr)
EA (1) EA012436B1 (fr)
HR (1) HRP20110402T1 (fr)
IL (2) IL184414A (fr)
MA (1) MA29244B1 (fr)
MX (1) MX2007008182A (fr)
NZ (1) NZ560468A (fr)
PL (1) PL1833507T3 (fr)
WO (1) WO2006072787A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005312062B2 (en) * 2004-12-01 2011-11-17 Aeras Global Tb Vaccine Foundation Electroporation of Mycobacterium and overexpression of antigens in Mycobacteria
US8691502B2 (en) 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
MX2011011186A (es) * 2009-04-24 2012-02-13 Una vacuna antituberculosis tb para evitar la reactivacion.
SG184103A1 (en) * 2010-03-19 2012-10-30 Red Flag Diagnostics Gmbh In vitro process for the quick determination of a patient's status relating to infection with mycobacterium tuberculosis
TWI638829B (zh) 2012-07-10 2018-10-21 法商傳斯堅公司 分枝桿菌抗原疫苗
WO2015104380A1 (fr) * 2014-01-09 2015-07-16 Transgene Sa Fusion d'antigènes mycobactériens hétérooligomères
AU2015353581A1 (en) * 2014-11-25 2017-06-15 Adaptive Biotechnologies Corporation Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
RU2665817C1 (ru) * 2017-10-25 2018-09-04 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации Вакцина рекомбинантная противотуберкулезная и адъювант для нее
US12398179B2 (en) 2019-03-14 2025-08-26 Sanford Burnham Prebys Medical Discovery Institute Nanomolar peptides and derivatives to differentially modulate ephrin receptors

Also Published As

Publication number Publication date
IL184414A (en) 2012-01-31
HRP20110402T1 (hr) 2011-07-31
CY1111549T1 (el) 2015-08-05
CA2592756A1 (fr) 2006-07-13
IL184414A0 (en) 2007-10-31
NZ560468A (en) 2010-05-28
JP2008526823A (ja) 2008-07-24
EA012436B1 (ru) 2009-10-30
WO2006072787A1 (fr) 2006-07-13
KR20070108518A (ko) 2007-11-12
MX2007008182A (es) 2008-02-19
EP1833507A1 (fr) 2007-09-19
AP2007004059A0 (en) 2007-08-31
JP2013010775A (ja) 2013-01-17
EP1833507B1 (fr) 2011-03-16
PL1833507T3 (pl) 2011-08-31
BRPI0606165A2 (pt) 2009-06-02
AU2006204382A1 (en) 2006-07-13
WO2006072787A8 (fr) 2006-09-14
IL217235A0 (en) 2012-01-31
AU2006204382B2 (en) 2011-05-12
EA200701440A1 (ru) 2008-02-28

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