MA29265B1 - Derives de 3-aryl-1, 2-benzisoxazole, et leur utilisation comme medicaments contre le cancer - Google Patents

Derives de 3-aryl-1, 2-benzisoxazole, et leur utilisation comme medicaments contre le cancer

Info

Publication number
MA29265B1
MA29265B1 MA30161A MA30161A MA29265B1 MA 29265 B1 MA29265 B1 MA 29265B1 MA 30161 A MA30161 A MA 30161A MA 30161 A MA30161 A MA 30161A MA 29265 B1 MA29265 B1 MA 29265B1
Authority
MA
Morocco
Prior art keywords
aryl
nr5r6
nitro
halogen
cancer drugs
Prior art date
Application number
MA30161A
Other languages
English (en)
Inventor
Luc Bertin
Chantal Carrez
Fabienne Thompson
Patrick Maillet
Jean-Marie Ruxer
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35058405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29265(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of MA29265B1 publication Critical patent/MA29265B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION CONCERNE LES NOUVEAUX PRODUITS DE FORMULE (I): DANS LAQUELLE A1 ET A2 REPRÉSENTENT CH OU N; X REPRÉSENTE CRA OU N; Y REPRÉSENTE CRB OU N; R1, R2, R3 ET R4 IDENTIQUES OU DIFFÉRENTS REPRÉSENTENT NOTAMMENT HYDROGÈNE, HALOGÈNE, CYANO, NITRO, TRIFLUOROMÉTHYLE, OR5, SR5, NR5R6, C(O)R5, C(O)OR5, C(O) NR5R6, S(O)R5, S(O)2R5, S(O)NR5R6, S(O)2NR5R6, NR6C(O)R5, NR6C(O)OR5, ALKYLES, ALKÉNYLES, ALKYNYLES, ARYLES, HÉTÉROARYLES, ARALKYLES OU HÉTÉROARALKYLES, TOUS ÉVENTUELLEMENT SUBSTITUÉS; RA REPRÉSENTE NOTAMMENT HALOGÈNE, HYDROXYLE, ALCOXY, NITRO; RB REPRÉSENTE NOTAMMENT HYDROGÈNE, HALOGÈNE, CYANO, NITRO, TRIFLUOROMÉTHYLE, -W-(CI- C3ALKYLE)M- R5 ; R5 ET R6 REPRÉSENTE NOTAMMENT ALKYLE, ARALKYLE OU HÉTÉROARALKYLES ÉVENTUELLEMENT SUBSTITUÉS; CES PRODUITS ÉTANT SOUS TOUTES LES FORMES ISOMÈRES ET LES SELS, À TITRE DE MÉDICAMENTS.
MA30161A 2005-02-22 2007-08-23 Derives de 3-aryl-1, 2-benzisoxazole, et leur utilisation comme medicaments contre le cancer MA29265B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501801A FR2882361A1 (fr) 2005-02-22 2005-02-22 Nouveaux derives de 3-aryl-1,2-benzisoxazole, compositions les contenant et leur utilisation

Publications (1)

Publication Number Publication Date
MA29265B1 true MA29265B1 (fr) 2008-02-01

Family

ID=35058405

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30161A MA29265B1 (fr) 2005-02-22 2007-08-23 Derives de 3-aryl-1, 2-benzisoxazole, et leur utilisation comme medicaments contre le cancer

Country Status (19)

Country Link
US (1) US20080070960A1 (fr)
EP (1) EP1861381A1 (fr)
JP (1) JP2008531493A (fr)
KR (1) KR20070110102A (fr)
CN (1) CN101146780A (fr)
AR (1) AR053684A1 (fr)
AU (1) AU2006217799A1 (fr)
BR (1) BRPI0606178A2 (fr)
CA (1) CA2597781A1 (fr)
EA (1) EA200701798A1 (fr)
FR (1) FR2882361A1 (fr)
IL (1) IL185166A0 (fr)
MA (1) MA29265B1 (fr)
MX (1) MX2007010278A (fr)
NO (1) NO20074631L (fr)
TW (1) TW200640884A (fr)
UY (1) UY29390A1 (fr)
WO (1) WO2006090052A1 (fr)
ZA (1) ZA200707080B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2907453B1 (fr) * 2006-10-24 2008-12-26 Sanofi Aventis Sa Nouveaux derives du fluorene,compositions les contenant et utilisation
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
FR2949467B1 (fr) 2009-09-03 2011-11-25 Sanofi Aventis Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
HUE037312T2 (hu) * 2012-12-19 2018-08-28 Celgene Quanticel Res Inc Hiszton demetiláz inhibitorok

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884814B2 (en) * 2001-12-13 2005-04-26 Wyeth Phenyl benzisoxazoles as estrogenic agents
CA2515726C (fr) * 2003-02-11 2012-07-10 Vernalis (Cambridge) Limited Isoxazoles
CA2530374C (fr) * 2003-06-27 2012-05-15 Kyowa Hakko Kogyo Co., Ltd. Inhibiteur de proteines de la famille hsp90
US20060257987A1 (en) * 2003-08-20 2006-11-16 Gonzalez Valcarcel Isabel Cris Ppar modulators

Also Published As

Publication number Publication date
CN101146780A (zh) 2008-03-19
CA2597781A1 (fr) 2006-08-31
UY29390A1 (es) 2006-10-02
AR053684A1 (es) 2007-05-16
AU2006217799A1 (en) 2006-08-31
EA200701798A1 (ru) 2008-02-28
TW200640884A (en) 2006-12-01
FR2882361A1 (fr) 2006-08-25
IL185166A0 (en) 2007-12-03
KR20070110102A (ko) 2007-11-15
ZA200707080B (en) 2008-11-26
EP1861381A1 (fr) 2007-12-05
NO20074631L (no) 2007-11-20
MX2007010278A (es) 2007-11-07
BRPI0606178A2 (pt) 2009-06-02
JP2008531493A (ja) 2008-08-14
WO2006090052A1 (fr) 2006-08-31
US20080070960A1 (en) 2008-03-20

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