MA29542B1 - Traitement des maladies hepatiques dans la pathogenese desquelles le fer joue un role - Google Patents

Traitement des maladies hepatiques dans la pathogenese desquelles le fer joue un role

Info

Publication number
MA29542B1
MA29542B1 MA30467A MA30467A MA29542B1 MA 29542 B1 MA29542 B1 MA 29542B1 MA 30467 A MA30467 A MA 30467A MA 30467 A MA30467 A MA 30467A MA 29542 B1 MA29542 B1 MA 29542B1
Authority
MA
Morocco
Prior art keywords
treatment
pathogenesis
role
hepatic diseases
iron plays
Prior art date
Application number
MA30467A
Other languages
English (en)
Inventor
Daniele Alberti
Peter Marks
Hanspeter Nick
Lisa Grace Rojkjaer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29542B1 publication Critical patent/MA29542B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'INVENTION CONCERNE L'UTILISATION D'ACIDE 4-[3,5-BIS-(2-HYDROXYPHÉNYL)-[1,2,4]-TRIAZOL-1-YL]BENZOÏQUE (APPELÉ ICI 'COMPOSÉ I') DANS LA FABRICATION DE COMPOSITIONS PHARMACEUTIQUES UTILES DANS LE TRAITEMENT DE MALADIES HÉPATIQUES HUMAINES DANS LA PATHOGENÈSE DESQUELLES LE FER JOUE UN RÔLE, NOTAMMENT DES MALADIES VIRALES, TELLES QUE L'HÉPATITE C CHRONIQUE, FACULTATIVEMENT ASSOCIÉES À DES AGENTS ANTIVIRAUX, ET DANS LE TRAITEMENT DE MALADIES NON VIRALES, TELLES QUE LA STÉATOHÉPATITE NON ALCOOLIQUE ET LA STÉATOSE HÉPATIQUE NON ALCOOLIQUE.
MA30467A 2005-05-31 2007-12-10 Traitement des maladies hepatiques dans la pathogenese desquelles le fer joue un role MA29542B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68584805P 2005-05-31 2005-05-31
US69280805P 2005-06-22 2005-06-22
US74678606P 2006-05-09 2006-05-09

Publications (1)

Publication Number Publication Date
MA29542B1 true MA29542B1 (fr) 2008-06-02

Family

ID=37106984

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30467A MA29542B1 (fr) 2005-05-31 2007-12-10 Traitement des maladies hepatiques dans la pathogenese desquelles le fer joue un role

Country Status (16)

Country Link
US (3) US20080199428A1 (fr)
EP (1) EP1893198A2 (fr)
JP (2) JP2008542380A (fr)
KR (2) KR20080003933A (fr)
AU (1) AU2006252718B2 (fr)
BR (1) BRPI0610873A2 (fr)
CA (1) CA2608709A1 (fr)
CR (1) CR9454A (fr)
EA (1) EA014772B1 (fr)
IL (1) IL187000A0 (fr)
MA (1) MA29542B1 (fr)
MX (1) MX2007015085A (fr)
NO (1) NO20076595L (fr)
SM (1) SMAP200700061A (fr)
TN (1) TNSN07447A1 (fr)
WO (1) WO2006130532A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
EP1736478B1 (fr) 2000-05-26 2015-07-22 IDENIX Pharmaceuticals, Inc. Procédés et compositions de traitement des flavivirus et des pestivirus
CN1678326A (zh) 2002-06-28 2005-10-05 埃迪尼克斯(开曼)有限公司 用于治疗黄病毒感染的2'－c－甲基－3'－o－l－缬氨酸酯核糖呋喃基胞苷
NZ537662A (en) 2002-06-28 2007-10-26 Idenix Cayman Ltd 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
LT1576138T (lt) 2002-11-15 2017-06-26 Idenix Pharmaceuticals Llc 2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija
AU2003300901A1 (en) 2002-12-12 2004-06-30 Idenix (Cayman) Limited Process for the production of 2'-branched nucleosides
CN101242857A (zh) * 2005-08-15 2008-08-13 弗·哈夫曼-拉罗切有限公司 用于HBV治疗的PEG-IFNa和利巴韦林
WO2008065123A2 (fr) * 2006-11-29 2008-06-05 Novartis Ag Sels et formes cristallines de l'acide 4-[3,5-bis(2-hydroxyphényl)-[1,2,4]triazol-1-yl]benzoïque
EP1927591A1 (fr) * 2006-11-29 2008-06-04 Novartis AG Formes polymorphes de deferasirox (ICL670)
EP2680859B1 (fr) * 2011-03-02 2022-04-27 Jerome Schentag Compositions, méthodes de traitement et diagnostics dans le traitement de la stéatose hépatique seule ou en association avec une infection par le virus de l'hépatite c
EP2583677A3 (fr) 2011-10-21 2013-07-03 Abbvie Inc. Procédés pour le traitement du VHC avec au moins deux agent antiviral à action direct, ribavirin mais sans interferon.
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
DE202012012955U1 (de) 2011-10-21 2014-07-14 Abbvie Inc. Eine Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen (DAAs) für die Verwendung zur Behandlung von HCV
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
US20130108573A1 (en) * 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc. Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease
EP3119401A4 (fr) * 2014-03-21 2017-12-13 Tobira Therapeutics, Inc. Cenicriviroc pour le traitement de la fibrose
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
GB202005054D0 (en) 2020-04-06 2020-05-20 Nemysis Ltd Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY129541A (en) * 1996-06-25 2007-04-30 Novartis Ag Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
JP4125011B2 (ja) * 2002-01-22 2008-07-23 株式会社 伊藤園 過剰鉄起因肝障害予防・治療剤及び過剰鉄起因肝障害予防・治療飲食物

Also Published As

Publication number Publication date
EA014772B1 (ru) 2011-02-28
WO2006130532A2 (fr) 2006-12-07
JP2008542380A (ja) 2008-11-27
US20080199428A1 (en) 2008-08-21
KR20080003933A (ko) 2008-01-08
NO20076595L (no) 2007-12-20
TNSN07447A1 (en) 2009-03-17
JP2013082726A (ja) 2013-05-09
MX2007015085A (es) 2008-01-17
CR9454A (es) 2008-04-16
KR20100018057A (ko) 2010-02-16
KR101174966B1 (ko) 2012-08-17
EP1893198A2 (fr) 2008-03-05
EA200702384A1 (ru) 2008-06-30
CA2608709A1 (fr) 2006-12-07
AU2006252718B2 (en) 2010-04-15
WO2006130532A3 (fr) 2007-11-22
SMAP200700061A (it) 2007-12-28
JP5869469B2 (ja) 2016-02-24
IL187000A0 (en) 2008-02-09
AU2006252718A1 (en) 2006-12-07
US20130109730A1 (en) 2013-05-02
US20100098662A1 (en) 2010-04-22
BRPI0610873A2 (pt) 2010-08-03

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