MA31093B1 - Vaccin - Google Patents

Vaccin

Info

Publication number
MA31093B1
MA31093B1 MA32087A MA32087A MA31093B1 MA 31093 B1 MA31093 B1 MA 31093B1 MA 32087 A MA32087 A MA 32087A MA 32087 A MA32087 A MA 32087A MA 31093 B1 MA31093 B1 MA 31093B1
Authority
MA
Morocco
Prior art keywords
fusion
protein
partner
proteins
antigen
Prior art date
Application number
MA32087A
Other languages
Arabic (ar)
English (en)
Inventor
Normand Blais
Denis Martin
Remi M Palmantier
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39300029&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA31093(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0700760A external-priority patent/GB0700760D0/en
Priority claimed from GB0701262A external-priority patent/GB0701262D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of MA31093B1 publication Critical patent/MA31093B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001189—PRAME
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE DES PROTÉINES DE FUSION COMPRENANT UN ANTIGÈNE DÉRIVÉ DE L'ANTIGÈNE DIT DE REJET DES TUMEURS PRAME (ÉGALEMENT NOMMÉ DAGE) LIÉ À UN PARTENAIRE DE FUSION IMMUNOLOGIQUE QUI FOURNIT DES ÉPITOPES DE LYMPHOCYTES T AUXILIAIRES, TELS QUE, PAR EXEMPLE, LA PROTÉINE D DE HAEMOPHILUS INFLUENZAE B, DES PROTÉINES PARTENAIRES DE FUSION COMPRENANT DES FRAGMENTS DE LA PROTÉINE D, DES PROCÉDÉS POUR LEUR PRÉPARATION ET LA FORMULATION DE VACCINS AINSI QUE LEUR UTILISATION DANS LE TRAITEMENT DE TOUT UN ÉVENTAIL DE CANCERS.
MA32087A 2007-01-15 2009-07-10 Vaccin MA31093B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0700760A GB0700760D0 (en) 2007-01-15 2007-01-15 Vaccine
GB0701262A GB0701262D0 (en) 2007-01-23 2007-01-23 Vaccine
PCT/EP2008/050290 WO2008087102A1 (fr) 2007-01-15 2008-01-11 Vaccin

Publications (1)

Publication Number Publication Date
MA31093B1 true MA31093B1 (fr) 2010-01-04

Family

ID=39300029

Family Applications (1)

Application Number Title Priority Date Filing Date
MA32087A MA31093B1 (fr) 2007-01-15 2009-07-10 Vaccin

Country Status (31)

Country Link
US (1) US20080187535A1 (fr)
EP (1) EP2114993B1 (fr)
JP (1) JP5391080B2 (fr)
KR (1) KR20090101313A (fr)
CN (1) CN101668770B (fr)
AR (1) AR064862A1 (fr)
AU (1) AU2008207025B2 (fr)
BR (1) BRPI0806463A2 (fr)
CA (1) CA2674552A1 (fr)
CL (1) CL2008000104A1 (fr)
CO (1) CO6210757A2 (fr)
CR (1) CR10971A (fr)
CY (1) CY1113760T1 (fr)
DK (1) DK2114993T3 (fr)
DO (1) DOP2009000167A (fr)
EA (1) EA016326B1 (fr)
ES (1) ES2393812T3 (fr)
HR (1) HRP20120828T1 (fr)
IL (1) IL199663A0 (fr)
JO (1) JO2840B1 (fr)
MA (1) MA31093B1 (fr)
MX (1) MX2009007571A (fr)
MY (1) MY153679A (fr)
NZ (1) NZ578285A (fr)
PE (2) PE20081686A1 (fr)
PL (1) PL2114993T3 (fr)
PT (1) PT2114993E (fr)
SI (1) SI2114993T1 (fr)
TW (1) TWI434697B (fr)
WO (1) WO2008087102A1 (fr)
ZA (1) ZA200904923B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009007572A (es) * 2007-01-15 2009-10-13 Glaxosmithkline Biolog Sa Proteinas de fusion que contienen los antigenos de rechazo de tumor ny-eso-1 y.
EP2408933A2 (fr) 2009-03-17 2012-01-25 MDxHealth SA Détection améliorée de l'expression de gènes
JP2012529269A (ja) * 2009-06-05 2012-11-22 ジ オハイオ ステイト ユニヴァーシティ リサーチ ファウンデーション 生体材料、組成物及び方法
GB0910046D0 (en) 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
GB201008682D0 (en) * 2010-05-25 2010-07-07 Vib Vzw Epitope tag for affinity based applications
GB201101331D0 (en) * 2011-01-26 2011-03-09 Glaxosmithkline Biolog Sa Compositions and uses
EP2734539A1 (fr) 2011-07-22 2014-05-28 GlaxoSmithKline Biologicals S.A. Purification de prame
GB201114919D0 (en) * 2011-08-30 2011-10-12 Glaxosmithkline Biolog Sa Method
GB201116248D0 (en) 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
RU2590701C2 (ru) * 2013-04-29 2016-07-10 Общество с ограниченной ответственностью "ГеноТехнология" Антигенная композиция и ее терапевтическое применение для профилактики и лечения онкологических заболеваний, рекомбинантная плазмидная днк, обеспечивающая синтез гибридного белка, а также способ получения белка
WO2015050158A1 (fr) 2013-10-01 2015-04-09 国立大学法人三重大学 Vaccin d'induction de lymphocytes t contenant une séquence interépitope favorisant une présentation d'antigène
CN105254767A (zh) * 2015-11-17 2016-01-20 重庆科润生物医药研发有限公司 一种Protein D与HER2融合蛋白及其制备方法和应用
EP3415159B1 (fr) 2016-02-08 2023-12-13 Mie University Médicament de prétraitement pour thérapie par perfusion de lymphocytes t pour tumeur résistante aux inhibiteurs de point de contrôle immunitaire
CA3035591A1 (fr) 2016-11-30 2018-06-07 Advaxis, Inc. Compositions immunogenes ciblant des mutations recurrentes du cancer et leurs procedes d'utilisation
CN108264550B (zh) * 2017-01-04 2021-04-23 香雪生命科学技术（广东）有限公司 一种识别源自于prame抗原短肽的tcr
CN108948184B (zh) * 2017-05-22 2021-04-23 香雪生命科学技术（广东）有限公司 一种识别衍生自prame抗原短肽的t细胞受体
CN109400697B (zh) * 2017-08-17 2021-04-23 香雪生命科学技术（广东）有限公司 一种识别prame抗原短肽的tcr及其相关组合物
WO2019061297A1 (fr) * 2017-09-29 2019-04-04 苏州工业园区唯可达生物科技有限公司 Peptide de fusion d'épitope de lymphocyte t auxiliaire cd4 et vaccin associé
CN111655714A (zh) * 2017-11-08 2020-09-11 阿德瓦希斯公司 来自癌症相关蛋白的免疫原性异变肽及其使用方法
CN109879957B (zh) * 2017-12-06 2022-03-18 香雪生命科学技术（广东）有限公司 针对prame的高亲和力t细胞受体
US20230190902A1 (en) * 2020-05-29 2023-06-22 Children's National Medical Center Identification of hla-restricted prame peptide epitopes, prame-specific t cells suitable for "off-the-shelf" treatment of cancer expressing prame
BR112023022765A2 (pt) 2021-05-05 2024-01-02 Immatics Biotechnologies Gmbh Proteínas de ligação ao antígeno que ligam especificamente o prame

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
KR100372375B1 (ko) * 1993-12-23 2003-04-21 머클한스피터 면역반응의강화방법
US5830753A (en) * 1994-09-30 1998-11-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof.
GB9717953D0 (en) * 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
ATE513042T1 (de) * 1998-02-05 2011-07-15 Glaxosmithkline Biolog Sa Tumorassoziierte antigenderivate der mage-familie,nukleinsäuresequenzen, die dafür kodieren, zur herstellung von fusionsproteinen und zusammensetzungen zur impfung
AU3158900A (en) * 1999-02-25 2000-09-14 Smithkline Beecham Biologicals (Sa) Immunogens comprising a peptide and a carrier derived from h.influenzae protein
WO2001000232A2 (fr) * 1999-06-29 2001-01-04 Smithkline Beecham Biologicals S.A. Vaccin
EP1196772A2 (fr) * 1999-07-08 2002-04-17 Stressgen Biotechnologies Corporation Stimulation d'une reponse de type th-1 in vitro

Also Published As

Publication number Publication date
AU2008207025A1 (en) 2008-07-24
AR064862A1 (es) 2009-04-29
MX2009007571A (es) 2009-07-22
ZA200904923B (en) 2012-12-27
HRP20120828T1 (hr) 2012-11-30
EP2114993B1 (fr) 2012-08-29
CO6210757A2 (es) 2010-10-20
CN101668770B (zh) 2013-06-12
WO2008087102A1 (fr) 2008-07-24
CA2674552A1 (fr) 2008-07-24
HK1138853A1 (en) 2010-09-03
PT2114993E (pt) 2012-11-28
BRPI0806463A2 (pt) 2011-09-06
SI2114993T1 (sl) 2012-12-31
MY153679A (en) 2015-03-13
PE20130324A1 (es) 2013-03-05
DOP2009000167A (es) 2009-07-15
CY1113760T1 (el) 2016-07-27
AU2008207025B2 (en) 2012-08-23
PE20081686A1 (es) 2008-12-25
EA200900795A1 (ru) 2010-02-26
TWI434697B (zh) 2014-04-21
IL199663A0 (en) 2010-04-15
KR20090101313A (ko) 2009-09-24
EA016326B1 (ru) 2012-04-30
CR10971A (es) 2009-09-09
PL2114993T3 (pl) 2013-01-31
JP2010515444A (ja) 2010-05-13
NZ578285A (en) 2011-12-22
JP5391080B2 (ja) 2014-01-15
DK2114993T3 (da) 2012-10-22
ES2393812T3 (es) 2012-12-28
CL2008000104A1 (es) 2008-07-18
CN101668770A (zh) 2010-03-10
US20080187535A1 (en) 2008-08-07
JO2840B1 (en) 2014-09-15
EP2114993A1 (fr) 2009-11-11
TW200902048A (en) 2009-01-16

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