MA32556B1 - Composition pharmaceutique - Google Patents
Composition pharmaceutiqueInfo
- Publication number
- MA32556B1 MA32556B1 MA33607A MA33607A MA32556B1 MA 32556 B1 MA32556 B1 MA 32556B1 MA 33607 A MA33607 A MA 33607A MA 33607 A MA33607 A MA 33607A MA 32556 B1 MA32556 B1 MA 32556B1
- Authority
- MA
- Morocco
- Prior art keywords
- active ingredient
- pharmaceutically active
- pharmaceutical composition
- stabilized
- preparation containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 4
- 239000007787 solid Substances 0.000 abstract 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
La présente invention concerne une composition pharmaceutique ou une préparation solide contenant un principe pharmaceutiquement actif stabilisé et un procédé de stabilisation de celle-ci. Selon la présente invention, une composition peut être pharmaceutiquement stabilisée par un contenu de principe pharmaceutiquement actif non peptidique possédant un groupe amino primaire ou secondaire, un excipient et un composé acide. Par ailleurs, une préparation solide contenant un principe pharmaceutiquement actif, un oxyde de titane, un plastifiant et un acide organique à chaîne peut renforcer la stabilité du principe pharmaceutiquement actif pendant une irradiation lumineuse.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008194219 | 2008-07-28 | ||
| PCT/JP2009/063708 WO2010013823A2 (fr) | 2008-07-28 | 2009-07-27 | Composition pharmaceutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA32556B1 true MA32556B1 (fr) | 2011-08-01 |
Family
ID=41327301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA33607A MA32556B1 (fr) | 2008-07-28 | 2011-02-11 | Composition pharmaceutique |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US9186411B2 (fr) |
| EP (2) | EP2309985B1 (fr) |
| JP (2) | JP5295356B2 (fr) |
| KR (1) | KR20110042334A (fr) |
| CN (3) | CN102743330B (fr) |
| AR (1) | AR072842A1 (fr) |
| AU (1) | AU2009277443A1 (fr) |
| BR (1) | BRPI0916689A2 (fr) |
| CA (2) | CA2936400C (fr) |
| CL (1) | CL2011000170A1 (fr) |
| CO (1) | CO6290638A2 (fr) |
| CR (1) | CR20110110A (fr) |
| DO (2) | DOP2011000033A (fr) |
| EA (2) | EA201201451A1 (fr) |
| EC (1) | ECSP11010855A (fr) |
| ES (2) | ES2660962T3 (fr) |
| GE (2) | GEP20146166B (fr) |
| IL (2) | IL210735A0 (fr) |
| MA (1) | MA32556B1 (fr) |
| MX (1) | MX2011000757A (fr) |
| MY (2) | MY156305A (fr) |
| NZ (2) | NZ602592A (fr) |
| PE (3) | PE20110591A1 (fr) |
| SG (1) | SG186685A1 (fr) |
| TW (2) | TW201010992A (fr) |
| UA (1) | UA103332C2 (fr) |
| UY (1) | UY32008A (fr) |
| WO (1) | WO2010013823A2 (fr) |
| ZA (1) | ZA201101198B (fr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013122260A1 (fr) | 2012-02-15 | 2013-08-22 | Takeda Pharmaceutical Company Limited | Comprimé |
| AR091567A1 (es) | 2012-06-27 | 2015-02-11 | Takeda Pharmaceutical | Preparacion liquida, metodo, kit de inyeccion |
| MY183976A (en) | 2012-09-19 | 2021-03-17 | Taiho Pharmaceutical Co Ltd | Pharmaceutical composition for oral administration with improved dissolution and/or absorption |
| EP3632482A1 (fr) * | 2013-03-14 | 2020-04-08 | Allergan, Inc. | Système en polymère pour fixer des implants dans des aiguilles de seringue |
| CN105330647A (zh) * | 2014-08-14 | 2016-02-17 | 江苏柯菲平医药股份有限公司 | 吡咯磺酰类衍生物、其制备方法及其在医药上的应用 |
| CN105985278A (zh) * | 2015-01-27 | 2016-10-05 | 江苏柯菲平医药股份有限公司 | 吡咯磺酰类衍生物、其制备方法及其在医药上的应用 |
| MA41850A (fr) | 2015-03-31 | 2018-02-06 | Takeda Pharmaceuticals Co | Nouvelles utilisations pharmaceutiques |
| CN108135915B (zh) | 2015-07-30 | 2021-06-25 | 武田药品工业株式会社 | 片剂 |
| CN105106203B (zh) * | 2015-08-17 | 2019-04-05 | 江苏豪森药业集团有限公司 | 富马酸沃诺拉赞的药物组合物及其制备方法 |
| CN105030725B (zh) * | 2015-08-26 | 2019-12-10 | 迪沙药业集团有限公司 | 一种富马酸沃诺拉赞肠溶组合物及其制备方法 |
| CN105030720B (zh) * | 2015-08-26 | 2019-12-10 | 迪沙药业集团有限公司 | 一种富马酸沃诺拉赞肠溶片及其制备方法 |
| CN107224438B (zh) * | 2016-03-25 | 2021-04-06 | 江苏豪森药业集团有限公司 | 富马酸沃诺拉赞药物组合物 |
| US11331316B2 (en) * | 2016-10-12 | 2022-05-17 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| CN106580903B (zh) * | 2016-11-17 | 2019-12-13 | 江苏豪森药业集团有限公司 | 罗红霉素缓释药物组合物 |
| CN106860852A (zh) * | 2017-02-17 | 2017-06-20 | 王清华 | 一种用于结合治疗胃病的粘液西药 |
| KR20200013714A (ko) | 2017-05-31 | 2020-02-07 | 베링거 인겔하임 인터내셔날 게엠베하 | (e)-4-(2-(아미노메틸)-3-플루오로알릴옥시)-n-3급-부틸벤즈아미드를 포함하는 약제학적 조성물 및 약제학적 투여 형태, 이들의 제조 방법, 이의 치료 방법 및 용도 |
| BR112020000318A2 (pt) | 2017-07-10 | 2020-07-14 | Takeda Pharmaceutical Company Limited | preparação |
| CN108558831B (zh) * | 2018-06-08 | 2021-07-27 | 上海璃道医药科技有限公司 | 取代吡咯-4-烷基胺类化合物及其用途 |
| KR102126576B1 (ko) | 2018-09-19 | 2020-06-24 | 주식회사 대웅제약 | 4-메톡시 피롤 유도체의 제조 방법 |
| CN109288722B (zh) * | 2018-11-09 | 2021-03-30 | 伯德创研(广州)生物科技有限公司 | 一种变色修正肤色的粉底及其制备方法 |
| CN110538153B (zh) * | 2019-09-26 | 2022-04-26 | 扬子江药业集团四川海蓉药业有限公司 | 一种高稳定性、快速释放的固体制剂及其制备方法 |
| CN115867260B (zh) * | 2020-04-24 | 2024-10-01 | 福尔克博士药物有限责任公司 | 用于乳糜泻的吡啶酮衍生物的全身制剂 |
| CN111973565A (zh) * | 2020-07-07 | 2020-11-24 | 南京海纳医药科技股份有限公司 | 一种含有富马酸沃诺拉赞的片剂及其溶出度测定方法 |
| CN114053239A (zh) * | 2020-08-01 | 2022-02-18 | 吉林汇康制药有限公司 | 一种富马酸伏诺拉生药物组合物及制备方法 |
| CN111943932B (zh) * | 2020-08-06 | 2023-07-14 | 四川国康药业有限公司 | 一种可以治疗消化性溃疡的3-吡啶磺酰-1-n-杂吡咯衍生物及其制备方法和用途 |
| EP4221704B1 (fr) * | 2020-10-01 | 2025-09-24 | Imago Biosciences Inc. | Formulations pharmaceutiques pour le traitement de maladies médiées par kdm1a |
| CN114853728B (zh) * | 2022-05-07 | 2023-11-07 | 四川制药制剂有限公司 | 一种富马酸伏诺拉生片及其制备方法 |
| CN115364065B (zh) * | 2022-08-23 | 2024-03-15 | 宁波高新区美诺华医药创新研究院有限公司 | 富马酸伏诺拉生片 |
| CN115944743B (zh) * | 2023-01-18 | 2025-08-08 | 山东诚成医药科技有限公司 | 一种富马酸伏诺拉生组合物及其制备方法 |
| CN116687873A (zh) * | 2023-05-26 | 2023-09-05 | 四川制药制剂有限公司 | 一种富马酸伏诺拉生片及其制备方法 |
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| CN117462507B (zh) * | 2023-12-28 | 2024-03-15 | 山东齐都药业有限公司 | 富马酸伏诺拉生药物组合物及其制备方法 |
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| AU2005291302A1 (en) | 2004-10-05 | 2006-04-13 | Altana Pharma Ag | Oral pharmaceutical preparation comprising a proton pump antagonist and a basic excipient |
| CN101247801B (zh) * | 2005-08-25 | 2012-08-22 | 协和发酵生化株式会社 | 血中酒精浓度上升抑制用组合物 |
| AU2006285641A1 (en) * | 2005-08-30 | 2007-03-08 | Takeda Pharmaceutical Company Limited | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors |
| CA2634637A1 (fr) | 2005-12-28 | 2007-07-05 | Takeda Pharmaceutical Company Limited | Preparation solide a liberation controlee |
| CN101516367A (zh) | 2006-09-15 | 2009-08-26 | 安斯泰来制药有限公司 | 对光稳定的雷莫司琼的固态医药组合物 |
| JP5074052B2 (ja) | 2007-02-13 | 2012-11-14 | 有限会社愛和ライト | 遊技機 |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| WO2009041705A2 (fr) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| WO2009041447A1 (fr) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| EP2226075A1 (fr) | 2007-11-22 | 2010-09-08 | The University of Tokyo | Matériau destiné à la prévention de l'adhérence tissulaire et matériau destiné à la prévention des contractures articulaires |
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2009
- 2009-07-27 EP EP09788013.2A patent/EP2309985B1/fr active Active
- 2009-07-27 AU AU2009277443A patent/AU2009277443A1/en not_active Abandoned
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- 2009-07-27 CN CN201210251154.9A patent/CN102743330B/zh active Active
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- 2009-07-27 CN CN201510088695.8A patent/CN104784180A/zh active Pending
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- 2009-07-27 CA CA2732243A patent/CA2732243C/fr active Active
- 2009-07-27 TW TW103115778A patent/TW201431552A/zh unknown
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