MA32622B1 - Derives de carbonate de quinuclidine et composition medicinale les comprenant - Google Patents

Derives de carbonate de quinuclidine et composition medicinale les comprenant

Info

Publication number
MA32622B1
MA32622B1 MA33683A MA33683A MA32622B1 MA 32622 B1 MA32622 B1 MA 32622B1 MA 33683 A MA33683 A MA 33683A MA 33683 A MA33683 A MA 33683A MA 32622 B1 MA32622 B1 MA 32622B1
Authority
MA
Morocco
Prior art keywords
same
medicinal composition
carbonate derivatives
quinuclidine
quinuclidine carbonate
Prior art date
Application number
MA33683A
Other languages
Arabic (ar)
English (en)
Inventor
Gabriele Amari
Maurizio Delcanale
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of MA32622B1 publication Critical patent/MA32622B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention porte sur des dérivés de carbonate de quinuclidine agissant en tant qu'antagonistes des récepteurs muscariniques, sur des procédés de préparation de tels dérivés, sur des compositions les comprenant et sur leur utilisation thérapeutique.
MA33683A 2008-08-08 2011-03-08 Derives de carbonate de quinuclidine et composition medicinale les comprenant MA32622B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08162066A EP2154136A1 (fr) 2008-08-08 2008-08-08 Dérivés de carbone de quinuclidine et ses compositions médicales
PCT/EP2009/005272 WO2010015324A1 (fr) 2008-08-08 2009-07-21 Dérivés de carbonate de quinuclidine et composition médicinale les comprenant

Publications (1)

Publication Number Publication Date
MA32622B1 true MA32622B1 (fr) 2011-09-01

Family

ID=40228074

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33683A MA32622B1 (fr) 2008-08-08 2011-03-08 Derives de carbonate de quinuclidine et composition medicinale les comprenant

Country Status (31)

Country Link
US (3) US8039483B2 (fr)
EP (2) EP2154136A1 (fr)
JP (1) JP2011530489A (fr)
KR (1) KR20110044221A (fr)
CN (1) CN102112474B (fr)
AR (1) AR072994A1 (fr)
AT (1) ATE551341T1 (fr)
AU (1) AU2009278306B2 (fr)
CA (1) CA2733380A1 (fr)
CO (1) CO6351790A2 (fr)
CY (1) CY1112724T1 (fr)
DK (1) DK2313404T3 (fr)
EA (1) EA019166B1 (fr)
ES (1) ES2384914T3 (fr)
GE (1) GEP20135744B (fr)
HR (1) HRP20120394T1 (fr)
IL (1) IL211103A (fr)
JO (1) JO2831B1 (fr)
MA (1) MA32622B1 (fr)
ME (1) ME01283A (fr)
MX (1) MX2011001504A (fr)
MY (1) MY156332A (fr)
NZ (1) NZ590987A (fr)
PL (1) PL2313404T3 (fr)
PT (1) PT2313404E (fr)
RS (1) RS52370B (fr)
SI (1) SI2313404T1 (fr)
TW (1) TWI455938B (fr)
UA (1) UA102857C2 (fr)
WO (1) WO2010015324A1 (fr)
ZA (1) ZA201100963B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2534957B1 (fr) 2007-12-14 2015-05-27 AeroDesigns, Inc Administration de produits sous forme d'aérosols
EP2154136A1 (fr) 2008-08-08 2010-02-17 CHIESI FARMACEUTICI S.p.A. Dérivés de carbone de quinuclidine et ses compositions médicales
EP2206712A1 (fr) 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. Dérivés d'amino-ester d'alcaloïde et sa composition médicale
RU2580312C2 (ru) 2010-04-21 2016-04-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ получения частиц с пониженным электростатическим зарядом
WO2011160919A1 (fr) 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Dérivés aminoester d'alkaloïdes et composition médicinale les comprenant
KR20130111968A (ko) 2010-06-22 2013-10-11 키에시 파르마슈티시 엣스. 피. 에이. 알칼로이드 아미노에스테르 유도체 및 이의 의약 조성물
CA2803459A1 (fr) 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Derives aminoester d'alcaloides et compositions medicinales les comprenant
WO2012041717A1 (fr) * 2010-09-30 2012-04-05 Chiesi Farmaceutici S.P.A. Utilisation de stéarate de magnésium dans des préparations en poudre sèche destinées à être inhalées
CN103168038A (zh) * 2010-10-20 2013-06-19 奇斯药制品公司 用于治疗咳嗽的碳酸酯衍生物
KR20130141534A (ko) 2010-11-26 2013-12-26 키에시 파르마슈티시 엣스. 피. 에이. 글리신 유도체 및 무스카린 수용체 길항제로서의 이들의 용도
LT2685986T (lt) * 2011-03-18 2020-03-10 Genzyme Corporation Gliukozilceramido sintazės slopiklis
RU2611627C2 (ru) * 2011-04-29 2017-02-28 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Алкалоидный эфир и карбаматные производные и их медицинские композиции
KR20140105746A (ko) 2011-12-30 2014-09-02 키에시 파르마슈티시 엣스. 피. 에이. 항무스카린제로서 1-아자헤테로시클릴아세트산의 퀴누클리딘 에스터, 이들의 제조 방법 및 이들의 의약 조성물
MA37975B2 (fr) * 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide
US9427376B2 (en) 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
PT3920912T (pt) 2019-02-04 2025-09-09 Genzyme Corp Tratamento de ciliopatias usando inibidores da glucosilceramida sintase (gcs)
IL295255A (en) 2020-02-03 2022-10-01 Genzyme Corp Methods for treating neurological symptoms associated with lysosomal storage diseases
IL300090A (en) 2020-07-24 2023-03-01 Genzyme Corp Pharmaceutical preparations containing VENGLUSTAT

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1345937B1 (fr) 2000-12-22 2005-09-28 Almirall Prodesfarma AG Derives de carbamate quinuclidine et leur utilisation comme antagonistes m3
CA2443346A1 (fr) * 2001-04-03 2002-12-05 Aryx Therapeutics Nouveaux composes anticholinergiques et procedes d'utilisation
CA2470956C (fr) 2001-12-20 2011-08-02 Laboratorios S.A.L.V.A.T., S.A. Derives de 1-alkyl-1- azoniabicyclo[2.2.2]octane carbamate
EP1882691A1 (fr) * 2006-07-26 2008-01-30 CHIESI FARMACEUTICI S.p.A. Dérivés de quinuclidine comme antagonistes M3
EP2154136A1 (fr) 2008-08-08 2010-02-17 CHIESI FARMACEUTICI S.p.A. Dérivés de carbone de quinuclidine et ses compositions médicales
EP2206712A1 (fr) 2008-12-23 2010-07-14 CHIESI FARMACEUTICI S.p.A. Dérivés d'amino-ester d'alcaloïde et sa composition médicale
CA2803418A1 (fr) 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Formulation de poudre seche comprenant un medicament antimuscarinique
CN103168038A (zh) 2010-10-20 2013-06-19 奇斯药制品公司 用于治疗咳嗽的碳酸酯衍生物
US20120220557A1 (en) 2011-02-17 2012-08-30 Chiesi Farmaceutici S.P.A. Liquid propellant-free formulation comprising an antimuscarinic drug
RU2611627C2 (ru) 2011-04-29 2017-02-28 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Алкалоидный эфир и карбаматные производные и их медицинские композиции

Also Published As

Publication number Publication date
MY156332A (en) 2016-02-15
RS52370B (sr) 2012-12-31
HRP20120394T1 (hr) 2012-06-30
CN102112474B (zh) 2014-01-29
EP2154136A1 (fr) 2010-02-17
UA102857C2 (en) 2013-08-27
ME01283A (fr) 2013-06-20
SI2313404T1 (sl) 2012-07-31
HK1156032A1 (en) 2012-06-01
US20110319444A1 (en) 2011-12-29
US8404712B2 (en) 2013-03-26
GEP20135744B (en) 2013-02-11
AR072994A1 (es) 2010-10-06
US20100035922A1 (en) 2010-02-11
AU2009278306A1 (en) 2010-02-11
KR20110044221A (ko) 2011-04-28
EA019166B1 (ru) 2014-01-30
CA2733380A1 (fr) 2010-02-11
JP2011530489A (ja) 2011-12-22
IL211103A (en) 2014-04-30
CN102112474A (zh) 2011-06-29
TW201011022A (en) 2010-03-16
NZ590987A (en) 2012-11-30
MX2011001504A (es) 2011-03-29
DK2313404T3 (da) 2012-06-04
EA201100161A1 (ru) 2011-10-31
WO2010015324A1 (fr) 2010-02-11
AU2009278306B2 (en) 2014-06-26
IL211103A0 (en) 2011-04-28
EP2313404A1 (fr) 2011-04-27
US20120004258A1 (en) 2012-01-05
JO2831B1 (en) 2014-09-15
US8440690B2 (en) 2013-05-14
PT2313404E (pt) 2012-07-02
PL2313404T3 (pl) 2012-09-28
CO6351790A2 (es) 2011-12-20
US8039483B2 (en) 2011-10-18
ZA201100963B (en) 2012-05-30
ATE551341T1 (de) 2012-04-15
TWI455938B (zh) 2014-10-11
ES2384914T3 (es) 2012-07-13
CY1112724T1 (el) 2016-02-10
EP2313404B1 (fr) 2012-03-28

Similar Documents

Publication Publication Date Title
CY1122853T1 (el) Σταθερα σκευασματα λινακλοτιδης
EA201190017A1 (ru) Аминоэфирные производные алкалоидов и их медицинские композиции
EA201100161A1 (ru) Производные хинуклидина карбоната и их медицинские композиции
CY1121843T1 (el) Σκευασματα ετανερσεπτης σταθεροποιημενα με ιοντα μαγνησιου
CY1123365T1 (el) Ενωσεις που εχουν δραστικοτητα ανταγωνιστη μουσκαρινικου υποδοχεα και αγωνιστη βητα2 αδρενεργικου υποδοχεα
CY1116328T1 (el) Παραγωγα 4 - αμινοπυριμιδινης και η χρηση τους ως ανταγωνιστων α2α υποδοχεων αδενοσινης
CL2012003604A1 (es) Compuestos heterociclicos derivados de piridina carboxamida sustituida; proceso de preparacion; composicion farmaceutica; combinacion farmaceutica; uso en el tratamiento de trastornos proliferativos celulares, enfermedad de parkinson, cancer, entre otros.
MY163055A (en) Polycyclic antagonists of lysophosphatidic acid receptors
IN2012DN02735A (fr)
IN2012DN02702A (fr)
IN2012DN00754A (fr)
PH12013501136A1 (en) Lysophosphatidic acid receptor antagonists and uses thereof
ME01532B (me) Jedinjenja
BR112012027743A2 (pt) ciclopropil dicarboxamidas e análogos exibindo atividades anticâncer e antiproliferativas
EA201100691A1 (ru) Антагонисты рецепторов лизофосфатидной кислоты
DOP2010000234A (es) Antagonistas n,n-disustituidos de aminoalquilbifenilo de receptores d2 de prostaglandina
CO6620050A2 (es) Derivados de aminopirimidina como moduladores de la lrrk2
UA98839C2 (en) N,n-disubstituted aminoalkylbiphenyl antagonists of prostaglandin d2 receptors
EA201270741A1 (ru) Пероральные композиции и липофильные соли метилналтрексона
EA201190142A1 (ru) Производные пиразола, используемые в качестве антагонистов рецептора ccr4
EA201290394A1 (ru) Морфолинотиазолы в качестве позитивных аллостерических модуляторов альфа 7
MY167575A (en) Heterocyclic compounds and use thereof as modulators of type iii receptor tyrosine kinases
CO6331304A2 (es) Derivados de tienopiridonas como activadores de proteina quinasa activados por amp (ampk)
MX381967B (es) Compuestos de 2,3-dihidrobenzofuran-5-ilo como inhibidores de quinasas dyrk.
MX2014000964A (es) Derivados aza heterociclicos sustituidos.