MA32841B1 - Composés de cycloundeca depsipeptides et leur utilisation comme médicament - Google Patents

Composés de cycloundeca depsipeptides et leur utilisation comme médicament

Info

Publication number
MA32841B1
MA32841B1 MA33902A MA33902A MA32841B1 MA 32841 B1 MA32841 B1 MA 32841B1 MA 33902 A MA33902 A MA 33902A MA 33902 A MA33902 A MA 33902A MA 32841 B1 MA32841 B1 MA 32841B1
Authority
MA
Morocco
Prior art keywords
compounds
dipseibeptides
cyclondica
drugs
hepatitis
Prior art date
Application number
MA33902A
Other languages
Arabic (ar)
English (en)
Inventor
Roland Wenger
Manfred Mutter
Patrick Garrouste
Robert Lysek
Olivier Turpin
Grégoire Vuagniaux
Valérie Nicolas
Zanolari Laura Novaroli
Rafael Crabbé
Original Assignee
Debio Rech Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debio Rech Pharma Sa filed Critical Debio Rech Pharma Sa
Publication of MA32841B1 publication Critical patent/MA32841B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention concerne des nouveaux composés de cycloundeca depsipeptides et leur utilisation comme médicament, en particulier comme agents antiviraux, et plus particulièrement pour la prévention ou le traitement des infections dues à l'hépatite C ou de troubles induits par l'éhpatite C.
MA33902A 2008-11-06 2011-05-31 Composés de cycloundeca depsipeptides et leur utilisation comme médicament MA32841B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2008002982 2008-11-06
PCT/IB2009/007361 WO2010052559A1 (fr) 2008-11-06 2009-11-06 Composés de cycloundeca depsipeptides et leur utilisation comme médicament.

Publications (1)

Publication Number Publication Date
MA32841B1 true MA32841B1 (fr) 2011-11-01

Family

ID=40795063

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33902A MA32841B1 (fr) 2008-11-06 2011-05-31 Composés de cycloundeca depsipeptides et leur utilisation comme médicament

Country Status (20)

Country Link
US (1) US8501683B2 (fr)
EP (1) EP2355837A1 (fr)
JP (1) JP5758806B2 (fr)
KR (1) KR20110093858A (fr)
CN (1) CN102202679B (fr)
AU (1) AU2009312535B2 (fr)
BR (1) BRPI0920502A2 (fr)
CA (1) CA2741829A1 (fr)
CO (1) CO6361943A2 (fr)
CR (1) CR20110284A (fr)
EA (1) EA020896B1 (fr)
EC (1) ECSP11011101A (fr)
IL (1) IL212672A (fr)
MA (1) MA32841B1 (fr)
MX (1) MX2011004881A (fr)
NZ (1) NZ593204A (fr)
TN (1) TN2011000204A1 (fr)
UA (1) UA102414C2 (fr)
WO (1) WO2010052559A1 (fr)
ZA (1) ZA201103752B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
WO2012145427A1 (fr) 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Méthodes de traitement du cancer à l'aide de cyclosporine et de dérivés de cyclosporine
WO2013169616A1 (fr) * 2012-05-07 2013-11-14 Novartis Ag Modulation pharmacocinétique par de l'alisporivir
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos
WO2014049540A2 (fr) * 2012-09-29 2014-04-03 Novartis Ag Peptides cycliques et utilisations en tant que médicaments
GB201217560D0 (en) * 2012-10-02 2012-11-14 Mitopharm Ltd Novel cyclic depsipeptide compounds and their uses
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
TWI780152B (zh) 2017-05-12 2022-10-11 日商中外製藥股份有限公司 環狀有機化合物的製造方法
RU2716706C1 (ru) * 2019-12-04 2020-03-16 Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" Способ получения полимерсодержащей композиции силибина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE110784T1 (de) * 1987-06-19 1994-09-15 Sandoz Ag Zyklische peptolide.
KR100695611B1 (ko) 2001-05-17 2007-03-14 주식회사 엘지생활건강 [감마 히드록시 엔-메틸 엘-루신4] 사이클로스포린유도체를 유효성분으로 하는 모발 성장 촉진제
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
ATE490778T1 (de) * 2004-10-01 2010-12-15 Debiopharm Sa Verwendung von äd-mealaü3-äetvalü4-ciclosporin zur behandlung von hepatitis-c-infektion

Also Published As

Publication number Publication date
CO6361943A2 (es) 2012-01-20
AU2009312535B2 (en) 2015-03-26
EA201170605A1 (ru) 2011-12-30
CN102202679A (zh) 2011-09-28
TN2011000204A1 (en) 2012-12-17
NZ593204A (en) 2013-02-22
US8501683B2 (en) 2013-08-06
AU2009312535A1 (en) 2011-06-23
JP5758806B2 (ja) 2015-08-05
WO2010052559A8 (fr) 2011-06-09
UA102414C2 (ru) 2013-07-10
CA2741829A1 (fr) 2010-05-14
CR20110284A (es) 2011-09-19
JP2012507576A (ja) 2012-03-29
US20110212057A1 (en) 2011-09-01
CN102202679B (zh) 2014-05-07
HK1167592A1 (en) 2012-12-07
IL212672A0 (en) 2011-07-31
ECSP11011101A (es) 2011-10-31
WO2010052559A1 (fr) 2010-05-14
KR20110093858A (ko) 2011-08-18
EP2355837A1 (fr) 2011-08-17
BRPI0920502A2 (pt) 2015-12-22
IL212672A (en) 2016-10-31
ZA201103752B (en) 2012-03-28
MX2011004881A (es) 2011-08-12
EA020896B1 (ru) 2015-02-27

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