MA37432A1 - Virus modifié de la maladie de marek, et vaccins préparés à partir de celui-ci - Google Patents

Virus modifié de la maladie de marek, et vaccins préparés à partir de celui-ci

Info

Publication number
MA37432A1
MA37432A1 MA37432A MA37432A MA37432A1 MA 37432 A1 MA37432 A1 MA 37432A1 MA 37432 A MA37432 A MA 37432A MA 37432 A MA37432 A MA 37432A MA 37432 A1 MA37432 A1 MA 37432A1
Authority
MA
Morocco
Prior art keywords
marke
modified
disease virus
prepared therefrom
viral agent
Prior art date
Application number
MA37432A
Other languages
English (en)
Inventor
Joyce Pritchard
Teshome Mebatsion
Michel Bublot
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of MA37432A1 publication Critical patent/MA37432A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/255Marek's disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne un vaccin efficace contre la maladie de marek, qui est préparé en utilisant un virus de la maladie de marek (mdv) recombinant, souche cvi988, ayant été transformé avec une construction d'adn étranger qui comprend une longue séquence répétée terminale d'un virus de la réticuloendothéliose. Cet agent viral inoffensif élicite une réponse immunitaire très protectrice dans un poulet contre une exposition au mdv virulent sans entraîner de degré significatif de pathogénicité. Des formulations adaptées du vaccin destiné à être utilisé chez les poulets comprennent une dose immunisante efficace de ce nouvel agent viral, conjointement à un véhicule ou un diluant pharmaceutiquement acceptables.
MA37432A 2012-03-22 2013-03-15 Virus modifié de la maladie de marek, et vaccins préparés à partir de celui-ci MA37432A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261614142P 2012-03-22 2012-03-22
PCT/US2013/032539 WO2013142377A2 (fr) 2012-03-22 2013-03-15 Virus modifié de la maladie de marek, et vaccins préparés à partir de celui-ci

Publications (1)

Publication Number Publication Date
MA37432A1 true MA37432A1 (fr) 2016-03-31

Family

ID=48045766

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37432A MA37432A1 (fr) 2012-03-22 2013-03-15 Virus modifié de la maladie de marek, et vaccins préparés à partir de celui-ci

Country Status (28)

Country Link
US (3) US20130251737A1 (fr)
EP (2) EP2827898B1 (fr)
JP (1) JP2015512396A (fr)
KR (5) KR102951567B1 (fr)
CN (1) CN104602706A (fr)
AP (1) AP2014007955A0 (fr)
AR (1) AR090472A1 (fr)
BR (1) BR112014023398A8 (fr)
CA (1) CA2868099C (fr)
CR (1) CR20140432A (fr)
DO (1) DOP2014000215A (fr)
EA (1) EA030866B1 (fr)
EC (1) ECSP14023407A (fr)
ES (1) ES2663610T3 (fr)
GE (1) GEP201706650B (fr)
GT (1) GT201400199A (fr)
HK (1) HK1255682A1 (fr)
IL (1) IL234721B (fr)
MA (1) MA37432A1 (fr)
MX (1) MX355332B (fr)
MY (1) MY169061A (fr)
NL (1) NL301087I2 (fr)
PE (1) PE20150323A1 (fr)
PH (1) PH12014502085B1 (fr)
TN (1) TN2014000393A1 (fr)
UA (1) UA117345C2 (fr)
WO (1) WO2013142377A2 (fr)
ZA (1) ZA201406884B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169061A (en) 2012-03-22 2019-02-12 Merial Inc Modified marek's disease virus, and vaccines made therefrom
CN106397602B (zh) * 2016-08-02 2019-06-18 青岛明勤生物科技有限公司 一种分子佐剂加强型鸡马立克氏病蛋白工程疫苗
WO2018119142A1 (fr) 2016-12-21 2018-06-28 Amgen Inc. Formulations d'anticorps anti-tnf alpha

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642574A (en) 1970-04-29 1972-02-15 Us Agriculture Method for producing vaccine for immunization of poultry against marek{3 s disease
US4160024A (en) 1978-05-01 1979-07-03 Cornell Research Foundation, Inc. Marek's disease vaccine
NL8401120A (nl) 1984-04-09 1985-11-01 Centraal Diergeneeskundig Inst Viruspreparaat, waarmee gevaccineerd kan worden tegen de ziekte van marek.
US4895718A (en) 1987-07-10 1990-01-23 The United States Of America, As Represented By The Secretary Of Agriculture Serotype 2 Marek's disease vaccine
US4895717A (en) 1987-07-10 1990-01-23 The United States Of America As Represented By The Secretary Of Agriculture Revertant serotype 1 Marek's disease vaccine
AU8444798A (en) 1997-06-30 1999-01-25 Centre National De La Recherche Scientifique Improved method for transferring nucleic acid into the striped muscle and combination therefor
US20050019348A1 (en) * 2003-07-21 2005-01-27 Reddy Sanjay M. Marek's disease virus vaccine
MY169061A (en) 2012-03-22 2019-02-12 Merial Inc Modified marek's disease virus, and vaccines made therefrom
US9113301B1 (en) 2014-06-13 2015-08-18 Snapchat, Inc. Geo-location based event gallery

Also Published As

Publication number Publication date
HK1255682A1 (en) 2019-08-23
WO2013142377A2 (fr) 2013-09-26
MY169061A (en) 2019-02-12
ES2663610T3 (es) 2018-04-16
PE20150323A1 (es) 2015-03-05
MX355332B (es) 2018-04-16
IL234721B (en) 2018-05-31
WO2013142377A3 (fr) 2014-01-23
ZA201406884B (en) 2015-11-25
UA117345C2 (uk) 2018-07-25
JP2015512396A (ja) 2015-04-27
EP2827898B1 (fr) 2017-12-20
CA2868099A1 (fr) 2013-09-26
ECSP14023407A (es) 2015-06-30
US20230310589A1 (en) 2023-10-05
KR102503316B1 (ko) 2023-02-23
GT201400199A (es) 2018-10-15
AP2014007955A0 (en) 2014-09-30
EP2827898A2 (fr) 2015-01-28
PH12014502085A1 (en) 2014-11-24
EA201401044A1 (ru) 2015-01-30
TN2014000393A1 (en) 2015-12-21
KR20140146136A (ko) 2014-12-24
AR090472A1 (es) 2014-11-12
CN104602706A (zh) 2015-05-06
US11510978B2 (en) 2022-11-29
US20190216920A1 (en) 2019-07-18
PH12014502085B1 (en) 2014-11-24
EP3326646A1 (fr) 2018-05-30
US12280106B2 (en) 2025-04-22
KR102951567B1 (ko) 2026-04-10
BR112014023398A2 (pt) 2017-07-11
BR112014023398A8 (pt) 2022-08-16
KR20190100431A (ko) 2019-08-28
KR20220008945A (ko) 2022-01-21
GEP201706650B (en) 2017-03-27
NL301087I2 (nl) 2022-03-11
CA2868099C (fr) 2020-12-15
KR20230028595A (ko) 2023-02-28
KR102586316B1 (ko) 2023-10-06
DOP2014000215A (es) 2015-04-15
MX2014011388A (es) 2014-10-14
CR20140432A (es) 2015-01-09
US20130251737A1 (en) 2013-09-26
EA030866B1 (ru) 2018-10-31
KR20230145532A (ko) 2023-10-17

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