MA38318A1 - Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer - Google Patents

Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Info

Publication number
MA38318A1
MA38318A1 MA38318A MA38318A MA38318A1 MA 38318 A1 MA38318 A1 MA 38318A1 MA 38318 A MA38318 A MA 38318A MA 38318 A MA38318 A MA 38318A MA 38318 A1 MA38318 A1 MA 38318A1
Authority
MA
Morocco
Prior art keywords
ionizing radiation
inorganic nanoparticles
cancer
compositions
treatment
Prior art date
Application number
MA38318A
Other languages
English (en)
Inventor
Agnès Pottier
Laurent Levy
Elsa Borghi
Original Assignee
Nanobiotix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobiotix filed Critical Nanobiotix
Publication of MA38318A1 publication Critical patent/MA38318A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1089—Electrons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des nanoparticules inorganiques activables pouvant être utilisées dans le secteur de la santé, en particulier de la santé humaine, pour perturber, modifier ou détruire des cellules, tissus ou organes cibles cancéreux. Elle concerne plus particulièrement des nanoparticules pouvant générer un effet thérapeutique significativement efficace, lorsqu'elles sont concentrées à l'intérieur de la tumeur et exposées à des rayonnements ionisants. L'invention concerne également des compositions pharmaceutiques contenant un ensemble de nanoparticules telles que définies précédemment, ainsi que leurs utilisations.
MA38318A 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer MA38318A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13305087 2013-01-25
PCT/EP2014/051367 WO2014114732A1 (fr) 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Publications (1)

Publication Number Publication Date
MA38318A1 true MA38318A1 (fr) 2017-02-28

Family

ID=47710064

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38318A MA38318A1 (fr) 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Country Status (22)

Country Link
US (4) US10098952B2 (fr)
EP (1) EP2948179B1 (fr)
JP (2) JP6619231B2 (fr)
KR (2) KR102225239B1 (fr)
CN (1) CN105120897B (fr)
AR (1) AR094577A1 (fr)
AU (1) AU2014209899B2 (fr)
BR (1) BR112015017490A2 (fr)
CA (3) CA3251146A1 (fr)
CY (1) CY1121838T1 (fr)
EA (1) EA034242B1 (fr)
IL (1) IL239767B (fr)
MA (1) MA38318A1 (fr)
MX (1) MX369664B (fr)
PL (1) PL2948179T3 (fr)
RS (1) RS59042B1 (fr)
SG (1) SG11201505277VA (fr)
SI (1) SI2948179T1 (fr)
TW (1) TW201442726A (fr)
UA (1) UA116007C2 (fr)
WO (1) WO2014114732A1 (fr)
ZA (1) ZA201505510B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1203353A1 (en) 2011-12-16 2015-10-30 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
UA116007C2 (uk) 2013-01-25 2018-01-25 Нанобіотікс Композиції неорганічних наночастинок у комбінації з іонізуючим випромінюванням для лікування раку
EP3043863B1 (fr) 2013-09-11 2019-12-04 The Board of Trustees of the Leland Stanford Junior University Réseaux de structures d'accélération et imagerie rapide pour faciliter des radiothérapies rapides
EP2886128A1 (fr) * 2013-12-20 2015-06-24 Nanobiotix Compositions pharmaceutiques comportant des nanoparticules, leur préparation et leur utilisation
US11096962B2 (en) 2015-05-28 2021-08-24 Nanobiotix Nanoparticles for use as a therapeutic vaccine
EA201991489A1 (ru) * 2016-12-21 2019-12-30 Нанобиотикс Наночастицы для применения для лечения нейронального нарушения
CA3047651A1 (fr) * 2016-12-21 2018-06-28 Nanobiotix Nanoparticules destinees a etre utilisees pour ameliorer les performances cerebrales ou pour traiter le stress
EP3424533A1 (fr) * 2017-07-05 2019-01-09 Nh Theraguix Procédés de traitement de la dépendance
CN111479571A (zh) 2017-07-21 2020-07-31 瓦里安医疗系统公司 超高剂量率辐射和治疗剂的使用方法
US20220249389A1 (en) 2019-07-12 2022-08-11 Oregon Health & Science University Immunotherapeutic constructs and methods of their use
WO2021011496A1 (fr) * 2019-07-12 2021-01-21 Oregon Health & Science University Constructions immunothérapeutiques et leurs procédés d'utilisation
JP2022540652A (ja) 2019-07-12 2022-09-16 オレゴン ヘルス アンド サイエンス ユニバーシティ 分裂期キナーゼ阻害剤と免疫チェックポイント阻害剤との同時送達のための治療用構築物
WO2021215952A1 (fr) 2020-04-24 2021-10-28 Общество С Ограниченной Ответственностью "Индженик" Procédé de production de particules de bactériophages de la famille levivirus
FR3160407A1 (fr) 2024-03-25 2025-09-26 Gcs Institut De Cancerologie Strasbourg Europe Complexe peptidique radiosensibilisant

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006244A2 (fr) 1998-07-30 2000-02-10 Hainfeld James F Particules metalliques de chargement dans des vesicules membranaires cellulaires et particule metallique utilisee pour l'imagerie et la therapie
IL154758A0 (en) * 2000-11-20 2003-10-31 Oncolytics Biotech Inc Method for optimally delivering virus to a solid tumor mass
US6756063B2 (en) * 2001-03-29 2004-06-29 Zoltan Laboratories, Llc Methods and compositions for the treatment of human and animal cancers
FR2884149B1 (fr) * 2005-04-12 2007-06-08 Henri Mehier Tube implantable destine a l'injection notamment de fluide caloporteur dans tout ou partie d'un tissu humain ou animal
EP2130553A1 (fr) * 2008-06-05 2009-12-09 Nanobiotix Nanoparticules inorganiques de haute densité pour détruire des cellules in-vivo
US8395131B2 (en) * 2009-06-20 2013-03-12 Xiaodong Wu Method for three dimensional (3D) lattice radiotherapy
EP2275137A1 (fr) 2009-07-10 2011-01-19 Nanobiotix Nanoparticules métalliques, leur préparation et utilisations
US20130225901A1 (en) 2010-04-05 2013-08-29 Nanospectra Biosciences, Inc. Enhancement of radiation therapy by targeted high-z nanoparticles
HK1203353A1 (en) * 2011-12-16 2015-10-30 Nanobiotix Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof
UA116007C2 (uk) 2013-01-25 2018-01-25 Нанобіотікс Композиції неорганічних наночастинок у комбінації з іонізуючим випромінюванням для лікування раку

Also Published As

Publication number Publication date
US20150374818A1 (en) 2015-12-31
CA3251146A1 (fr) 2025-07-09
US10098952B2 (en) 2018-10-16
TW201442726A (zh) 2014-11-16
UA116007C2 (uk) 2018-01-25
CA2897362C (fr) 2023-02-14
SG11201505277VA (en) 2015-08-28
SI2948179T1 (sl) 2019-09-30
ZA201505510B (en) 2016-12-21
CY1121838T1 (el) 2020-07-31
US20210283256A1 (en) 2021-09-16
AU2014209899A1 (en) 2015-07-23
WO2014114732A1 (fr) 2014-07-31
JP2016505061A (ja) 2016-02-18
MX2015009409A (es) 2016-03-16
MX369664B (es) 2019-11-14
BR112015017490A2 (pt) 2017-07-11
EP2948179B1 (fr) 2019-06-19
JP6619231B2 (ja) 2019-12-11
US20240100163A1 (en) 2024-03-28
CA3179586A1 (fr) 2014-07-31
RS59042B1 (sr) 2019-08-30
KR102225239B1 (ko) 2021-03-09
US11020480B2 (en) 2021-06-01
US11819548B2 (en) 2023-11-21
IL239767A0 (en) 2015-08-31
CN105120897A (zh) 2015-12-02
CA3179586C (fr) 2025-07-08
US20190008962A1 (en) 2019-01-10
HK1216609A1 (en) 2016-11-25
EA201591378A1 (ru) 2016-04-29
IL239767B (en) 2018-10-31
KR20150108923A (ko) 2015-09-30
KR20210027536A (ko) 2021-03-10
EP2948179A1 (fr) 2015-12-02
CN105120897B (zh) 2017-12-05
CA2897362A1 (fr) 2014-07-31
AU2014209899B2 (en) 2018-05-24
EA034242B1 (ru) 2020-01-21
PL2948179T3 (pl) 2019-10-31
AR094577A1 (es) 2015-08-12
KR102385193B1 (ko) 2022-04-12
JP2018168162A (ja) 2018-11-01

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