MA38318A1 - Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer - Google Patents

Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Info

Publication number
MA38318A1
MA38318A1 MA38318A MA38318A MA38318A1 MA 38318 A1 MA38318 A1 MA 38318A1 MA 38318 A MA38318 A MA 38318A MA 38318 A MA38318 A MA 38318A MA 38318 A1 MA38318 A1 MA 38318A1
Authority
MA
Morocco
Prior art keywords
ionizing radiation
inorganic nanoparticles
cancer
compositions
treatment
Prior art date
Application number
MA38318A
Other languages
English (en)
Inventor
Agnès Pottier
Laurent Levy
Elsa Borghi
Original Assignee
Nanobiotix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobiotix filed Critical Nanobiotix
Publication of MA38318A1 publication Critical patent/MA38318A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1089—Electrons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des nanoparticules inorganiques activables pouvant être utilisées dans le secteur de la santé, en particulier de la santé humaine, pour perturber, modifier ou détruire des cellules, tissus ou organes cibles cancéreux. Elle concerne plus particulièrement des nanoparticules pouvant générer un effet thérapeutique significativement efficace, lorsqu'elles sont concentrées à l'intérieur de la tumeur et exposées à des rayonnements ionisants. L'invention concerne également des compositions pharmaceutiques contenant un ensemble de nanoparticules telles que définies précédemment, ainsi que leurs utilisations.
MA38318A 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer MA38318A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13305087 2013-01-25
PCT/EP2014/051367 WO2014114732A1 (fr) 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Publications (1)

Publication Number Publication Date
MA38318A1 true MA38318A1 (fr) 2017-02-28

Family

ID=47710064

Family Applications (1)

Application Number Title Priority Date Filing Date
MA38318A MA38318A1 (fr) 2013-01-25 2014-01-24 Compositions de nanoparticules inorganiques combinées à des rayonnements ionisants pour le traitement du cancer

Country Status (22)

Country Link
US (4) US10098952B2 (fr)
EP (1) EP2948179B1 (fr)
JP (2) JP6619231B2 (fr)
KR (2) KR102385193B1 (fr)
CN (1) CN105120897B (fr)
AR (1) AR094577A1 (fr)
AU (1) AU2014209899B2 (fr)
BR (1) BR112015017490A2 (fr)
CA (3) CA2897362C (fr)
CY (1) CY1121838T1 (fr)
EA (1) EA034242B1 (fr)
IL (1) IL239767B (fr)
MA (1) MA38318A1 (fr)
MX (1) MX369664B (fr)
PL (1) PL2948179T3 (fr)
RS (1) RS59042B1 (fr)
SG (1) SG11201505277VA (fr)
SI (1) SI2948179T1 (fr)
TW (1) TW201442726A (fr)
UA (1) UA116007C2 (fr)
WO (1) WO2014114732A1 (fr)
ZA (1) ZA201505510B (fr)

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JP6042450B2 (ja) 2011-12-16 2016-12-14 ナノビオティックスＮａｎｏｂｉｏｔｉｘ 金属材料および酸化ハフニウム材料を含むナノ粒子、その製造および使用
PL2948179T3 (pl) 2013-01-25 2019-10-31 Nanobiotix Kompozycje zawierające nanocząstki tlenku hafnu(iv) lub tlenku renu(iv) w połączeniu z promieniowaniem jonizującym do leczenia nowotworu
WO2015102680A2 (fr) 2013-09-11 2015-07-09 The Board Of Trustees Of The Leland Stanford Junior University Méthodes et systèmes de modulation de l'intensité d'un faisceau pour faciliter des traitements radiothérapeutiques rapides
EP2886128A1 (fr) * 2013-12-20 2015-06-24 Nanobiotix Compositions pharmaceutiques comportant des nanoparticules, leur préparation et leur utilisation
JP2018516256A (ja) 2015-05-28 2018-06-21 ナノビオティックスＮａｎｏｂｉｏｔｉｘ 治療用ワクチンとしての使用のためのナノ粒子
US11247054B2 (en) * 2016-12-21 2022-02-15 Nanobiotix S.A. Nanoparticles for use for enhancing brain performances or for treating stress
AU2017384425B2 (en) * 2016-12-21 2023-08-31 Nanobiotix Nanoparticles for use for treating a neuronal disorder
EP3424533A1 (fr) * 2017-07-05 2019-01-09 Nh Theraguix Procédés de traitement de la dépendance
US11173325B2 (en) 2017-07-21 2021-11-16 Varian Medical Systems, Inc. Methods of use of ultra-high dose rate radiation and therapeutic agent
JP2022540652A (ja) 2019-07-12 2022-09-16 オレゴン ヘルス アンド サイエンス ユニバーシティ 分裂期キナーゼ阻害剤と免疫チェックポイント阻害剤との同時送達のための治療用構築物
US20220249389A1 (en) * 2019-07-12 2022-08-11 Oregon Health & Science University Immunotherapeutic constructs and methods of their use
EP4141110A4 (fr) 2020-04-24 2025-04-09 Sf Biotech Laboratuvar Danismanlik Anonim Sirketi Procédé de production de particules de bactériophages de la famille levivirus
FR3160407A1 (fr) 2024-03-25 2025-09-26 Gcs Institut De Cancerologie Strasbourg Europe Complexe peptidique radiosensibilisant

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AU2002218087A1 (en) * 2000-11-20 2002-05-27 Oncolytics Biotech Inc. Method for optimally delivering virus to a solid tumor mass
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EP2670393B8 (fr) 2011-01-31 2016-10-05 Nanobiotix Procédé de surveillance de la libération par des liposomes d'un produit d'intérêt au moyen de nanoparticules superparamagnétiques
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JP6042450B2 (ja) 2011-12-16 2016-12-14 ナノビオティックスＮａｎｏｂｉｏｔｉｘ 金属材料および酸化ハフニウム材料を含むナノ粒子、その製造および使用
PL2948179T3 (pl) 2013-01-25 2019-10-31 Nanobiotix Kompozycje zawierające nanocząstki tlenku hafnu(iv) lub tlenku renu(iv) w połączeniu z promieniowaniem jonizującym do leczenia nowotworu
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AU2017384425B2 (en) 2016-12-21 2023-08-31 Nanobiotix Nanoparticles for use for treating a neuronal disorder
AU2017384538A1 (en) 2016-12-21 2019-08-01 Nanobiotix Coated nanoparticles for use for modulating electrical polarization of neurons
US11247054B2 (en) 2016-12-21 2022-02-15 Nanobiotix S.A. Nanoparticles for use for enhancing brain performances or for treating stress
PT3727402T (pt) 2017-12-19 2024-11-07 Nanobiotix Nanopartículas para utilização na melhoria dos desempenhos cerebrais ou no tratamento do stress
CN111886004A (zh) 2017-12-19 2020-11-03 纳米生物技术公司 用于治疗神经元障碍的纳米粒子
EP4157457A1 (fr) 2020-05-26 2023-04-05 Nanobiotix Nanoparticules, rayonnement ionisant et leurs combinaisons thérapeutiques innovantes

Also Published As

Publication number Publication date
CA3251146A1 (fr) 2025-07-09
UA116007C2 (uk) 2018-01-25
CN105120897B (zh) 2017-12-05
EP2948179A1 (fr) 2015-12-02
US20190008962A1 (en) 2019-01-10
WO2014114732A1 (fr) 2014-07-31
US20150374818A1 (en) 2015-12-31
US20210283256A1 (en) 2021-09-16
US10098952B2 (en) 2018-10-16
KR102225239B1 (ko) 2021-03-09
TW201442726A (zh) 2014-11-16
US12653890B2 (en) 2026-06-16
AU2014209899A1 (en) 2015-07-23
SG11201505277VA (en) 2015-08-28
US20240100163A1 (en) 2024-03-28
JP2016505061A (ja) 2016-02-18
IL239767A0 (en) 2015-08-31
CN105120897A (zh) 2015-12-02
AR094577A1 (es) 2015-08-12
CA3179586C (fr) 2025-07-08
EA201591378A1 (ru) 2016-04-29
ZA201505510B (en) 2016-12-21
MX2015009409A (es) 2016-03-16
JP6619231B2 (ja) 2019-12-11
CY1121838T1 (el) 2020-07-31
JP2018168162A (ja) 2018-11-01
RS59042B1 (sr) 2019-08-30
IL239767B (en) 2018-10-31
US11819548B2 (en) 2023-11-21
PL2948179T3 (pl) 2019-10-31
MX369664B (es) 2019-11-14
KR20150108923A (ko) 2015-09-30
CA2897362A1 (fr) 2014-07-31
KR102385193B1 (ko) 2022-04-12
EA034242B1 (ru) 2020-01-21
CA3179586A1 (fr) 2014-07-31
HK1216609A1 (en) 2016-11-25
SI2948179T1 (sl) 2019-09-30
US11020480B2 (en) 2021-06-01
AU2014209899B2 (en) 2018-05-24
EP2948179B1 (fr) 2019-06-19
CA2897362C (fr) 2023-02-14
BR112015017490A2 (pt) 2017-07-11
KR20210027536A (ko) 2021-03-10

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