MA40458A - Méthodes de traitement du cancer du col de l'utérus - Google Patents

Méthodes de traitement du cancer du col de l'utérus

Info

Publication number
MA40458A
MA40458A MA040458A MA40458A MA40458A MA 40458 A MA40458 A MA 40458A MA 040458 A MA040458 A MA 040458A MA 40458 A MA40458 A MA 40458A MA 40458 A MA40458 A MA 40458A
Authority
MA
Morocco
Prior art keywords
methods
cervical cancer
treating cervical
cervical tumor
treatment
Prior art date
Application number
MA040458A
Other languages
English (en)
Inventor
Hyun-Tak Jin
Hye Seong Lim
Eun Joo Nam
You Suk Suh
Original Assignee
Genexine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genexine Inc filed Critical Genexine Inc
Publication of MA40458A publication Critical patent/MA40458A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20071—Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)

Abstract

La présente invention concerne le traitement d'une tumeur du col de l'utérus provoquée par une infection à papillomavirus humain (hpv). En particulier, l'invention concerne des méthodes pour améliorer le traitement de tumeurs du col de l'utérus et des méthodes pour le traitement des tumeurs du col de l'utérus provoquée par une infection par le hpv à l'aide d'un polynucléotide codant pour une protéine de fusion e6/e7.
MA040458A 2014-08-15 2015-08-14 Méthodes de traitement du cancer du col de l'utérus MA40458A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462038134P 2014-08-15 2014-08-15
US201462039270P 2014-08-19 2014-08-19

Publications (1)

Publication Number Publication Date
MA40458A true MA40458A (fr) 2016-02-18

Family

ID=55303926

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040458A MA40458A (fr) 2014-08-15 2015-08-14 Méthodes de traitement du cancer du col de l'utérus

Country Status (11)

Country Link
US (2) US11135262B2 (fr)
EP (1) EP3193905B1 (fr)
JP (2) JP2017525760A (fr)
KR (1) KR102523984B1 (fr)
CN (1) CN107073070A (fr)
AU (1) AU2015302930C1 (fr)
BR (1) BR112017002809A2 (fr)
CA (1) CA2957128C (fr)
MA (1) MA40458A (fr)
MX (1) MX2017002081A (fr)
WO (1) WO2016024255A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015302930C1 (en) 2014-08-15 2023-06-01 Genexine, Inc. Methods of treating cervical cancer
CN106632694B (zh) * 2017-01-24 2021-02-12 南京益康生物医药有限公司 一种重组蛋白及药物组合物与应用
JP7457642B2 (ja) * 2017-04-03 2024-03-28 ビオンテック ユーエス インコーポレイテッド タンパク質抗原およびその使用
KR102286397B1 (ko) 2018-02-02 2021-08-05 주식회사 에스엘백시젠 신규 백신 면역보조제
KR102222582B1 (ko) * 2018-02-02 2021-03-04 주식회사 에스엘백시젠 신규 다가 hpv 백신 조성물
EP3752195A4 (fr) * 2018-02-14 2021-11-17 Viela Bio, Inc. Anticorps dirigés contre le ligand du récepteur 3 de la tyrosine kinase 3 du sarcome de mcdonough félin (fms) (flt3l) et leurs utilisations pour le traitement de maladies auto-immunes et inflammatoires
US12404306B2 (en) 2018-03-06 2025-09-02 Precigen, Inc. Human papillomavirus vaccines and uses of the same
WO2019204634A1 (fr) * 2018-04-20 2019-10-24 Stc. Unm Rap1-gtp, rac1-gtp et ligand de tyrosine kinase 3 de type fms (flt3-l) en tant que biomarqueurs pour la détection précoce d'une septicémie
AU2020234003B2 (en) * 2019-03-11 2026-02-12 Evaxion A/S Nucleic acid vaccination using neo-epitope encoding constructs
EP3860316A1 (fr) * 2020-01-30 2021-08-04 Erbe Elektromedizin GmbH Plasmas, médias, espèces, systèmes, procédés
US11883479B2 (en) * 2020-04-24 2024-01-30 Genexine, Inc. Method for treating cervical cancer
WO2023172036A1 (fr) 2022-03-10 2023-09-14 주식회사 제넥신 Thérapie de dosage de médicament de triple association pour le traitement du cancer de la tête et du cou
AU2023414262B2 (en) * 2022-12-29 2025-08-14 Rinuagene Biotechnology Co., Ltd. Polynucleotide molecule for preventing or treating hpv infection-related diseases
TW202440933A (zh) * 2023-03-01 2024-10-16 大陸商仁景（蘇州）生物科技有限公司 編碼ｒｎａ的工程化ｄｎａ分子及其用途
WO2025092908A1 (fr) * 2023-11-01 2025-05-08 仁景(苏州)生物科技有限公司 Vaccin à arnm pour le traitement de maladies associées à une infection par vph

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
EP0279582A3 (fr) 1987-02-17 1989-10-18 Pharming B.V. Séquences d'ADN pour diriger des protéines vers les glandes mammaires afin d'être sécrétées efficacement
US5633076A (en) 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5827690A (en) 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
AUPN015794A0 (en) 1994-12-20 1995-01-19 Csl Limited Variants of human papilloma virus antigens
KR100201584B1 (ko) 1996-07-12 1999-06-15 손경식 사람 파필로마 바이러스 18형 이6 단백질에 대한 인체의 면역성 조절 기능을 갖는 펩타이드
GB9717953D0 (en) 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
EP2100620A1 (fr) 1999-09-16 2009-09-16 Eisai Corporation of North America Acides nucléiques codant les polypeptides de polyépitopes
ES2284559T3 (es) 2001-03-23 2007-11-16 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Genes y proteinas e6 y e7 modificados del vph utiles como vacuna.
KR100900249B1 (ko) 2001-12-07 2009-05-29 포항공과대학교 산학협력단 ＳＩＶｍａｃ239의 면역원성 플라스미드 및 이들을 함유한ＡＩＤＳ ＤＮＡ 백신
US7223408B2 (en) 2002-10-03 2007-05-29 Wyeth Holdings Corporation Human papillomavirus polypeptides and immunogenic compositions
CN1299769C (zh) 2005-01-31 2007-02-14 中国医学科学院肿瘤医院肿瘤研究所 人乳头瘤病毒和热休克蛋白重组蛋白疫苗及其用途
EP1757615B1 (fr) 2005-08-24 2011-08-24 Healthbanks Biotech Co., Ltd. Protéine de fusion pour inhiber le cancer du cervix
US7732166B2 (en) 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US8137674B2 (en) 2006-04-19 2012-03-20 Postech Foundation Compositions comprising HPV polypeptides and immunoenhancement peptides for the treatment and prevention of cervical cancer
WO2008046251A1 (fr) * 2006-10-19 2008-04-24 Sunbio Biotech Pharmaceuticals(Tianjin) Co., Ltd. Protéines hybrides contenant un domaine n de la calréticuline humaine et des protéines e6 ou e7 du papillomavirus humain de type 16, et utilisations associées
DE102008010954A1 (de) 2008-02-25 2009-08-27 Cichon, Günter, Prof.Dr. DNA-Vakzine zur Therapie und Prophylaxe von Gebärmutterhalskrebs und seinen prämalignen Vorstufen
KR101166516B1 (ko) * 2009-07-02 2012-07-20 주식회사 바이오드 사람 파필로마바이러스 변형체 및 면역 증강제를 포함하는 자궁경부암 예방 또는 치료용 조성물
EP2377879A1 (fr) 2010-04-14 2011-10-19 Deutsches Krebsforschungszentrum Protéines de fusion HPV E7 à terminaison N
PL2604629T3 (pl) * 2010-08-13 2018-08-31 Genexine, Inc. Kompozycja do zapobiegania lub leczenia raka szyjki macicy ze wzmacniaczem odporności przeciwko wirusowi brodawczaka ludzkiego
CN102154325B (zh) * 2011-01-01 2013-08-21 上海生物制品研究所有限责任公司 针对人乳头瘤状病毒的疫苗及其制法和用途
KR102057265B1 (ko) * 2011-12-21 2019-12-18 백시바디 에이에스 Ｈｐｖ에 대한 백신들
AU2015302930C1 (en) 2014-08-15 2023-06-01 Genexine, Inc. Methods of treating cervical cancer

Also Published As

Publication number Publication date
US20170304385A1 (en) 2017-10-26
AU2015302930C1 (en) 2023-06-01
CA2957128C (fr) 2023-09-26
BR112017002809A2 (pt) 2017-12-19
EP3193905A4 (fr) 2018-05-09
AU2015302930B2 (en) 2020-11-26
US20220096589A1 (en) 2022-03-31
CA2957128A1 (fr) 2016-02-18
US11135262B2 (en) 2021-10-05
MX2017002081A (es) 2017-05-23
AU2015302930A1 (en) 2017-02-23
EP3193905A1 (fr) 2017-07-26
EP3193905B1 (fr) 2024-04-03
CN107073070A (zh) 2017-08-18
JP2017525760A (ja) 2017-09-07
JP7355399B2 (ja) 2023-10-03
KR20170045254A (ko) 2017-04-26
KR102523984B1 (ko) 2023-04-20
WO2016024255A1 (fr) 2016-02-18
JP2021119174A (ja) 2021-08-12

Similar Documents

Publication Publication Date Title
JOP20200192A1 (ar) أجسام مضادة لـ tigit
MX2017002081A (es) Metodo para tratar cancer de cuello uterino.
MX2022007522A (es) Anticuerpos anti-cd27.
MX2021006581A (es) Bacterias modificadas para tratar enfermedades asociadas con hiperamonemia.
MX2018012880A (es) Metodos para proporcionar arn de hebra sencilla.
GB2541571A (en) Pharmaceutical compositions
NZ731467A (en) Anti-tim3 antibodies and methods of use
MX2022008523A (es) Compuestos que interactuan con glicanos y metodos de uso.
GEP20217317B (en) Combination therapy for the treatment of cancer
NZ723884A (en) Methods of treating alzheimer’s disease
EA201800148A1 (ru) Оспенная вакцина для лечения рака
WO2017079570A3 (fr) Oligonucléotides à permutation épissage et méthodes d'utilisation
TW201613587A (en) Medical treatments based on anamorelin
MX2017006026A (es) Apilimod para uso en el tratamiento de cancer colorrectal.
MX2017000306A (es) Metodos para tratar hipotension.
ZA201708686B (en) Nanoparticles for use as a therapeutic vaccine
WO2013162981A3 (fr) Écarteurs d'implants mammaires pour le traitement des infections périprothétiques des implants mammaires
EP3549582A3 (fr) Nouveaux analogues de la capsazépine pour le traitement du cancer et d'autres maladies prolifératives
MX2017013666A (es) Terapia de combinacion de agente anti-fuctactico y agente de inmunoterapia y composiciones para el tratamiento de cancer.
SG10201903630UA (en) Iminosugars useful for the treatment of viral diseases
MA39718A (fr) Compositions et méthodes d'utilisation de celles-ci
GB2546703A (en) Compounds
UA107743C2 (ru) Способ лечения аденокарциномы
UA105871C2 (uk) Спосіб хірургічної корекції вродженої вентральної девіації статевого члена за горпинченком-ситенком